Gert Mayer

Summary

Affiliation: University of Innsbruck
Country: Austria

Publications

  1. pmc Bloodstream infection following 217 consecutive systemic-enteric drained pancreas transplants
    Natalie Berger
    Department of General and Transplant Surgery, Medical University, Innsbruck, Austria
    BMC Infect Dis 6:127. 2006
  2. ncbi request reprint ACE genotype and ACE inhibitor response in kidney disease: a perspective
    Gert Mayer
    Division of Nephrology, University of Innsbruck, Austria
    Am J Kidney Dis 40:227-35. 2002
  3. doi request reprint Markers of cellular senescence in zero hour biopsies predict outcome in renal transplantation
    Christian Koppelstaetter
    Division of Nephrology, Department of Internal Medicine, Medical University Innsbruck, Innsbruck, Austria
    Aging Cell 7:491-7. 2008
  4. ncbi request reprint Failure of BCL-2 up-regulation in proximal tubular epithelial cells of donor kidney biopsy specimens is associated with apoptosis and delayed graft function
    Christoph Schwarz
    Department of Internal Medicine III, Division of Nephrology, University of Vienna, Austria
    Lab Invest 82:941-8. 2002
  5. ncbi request reprint Reliability of t7-based mRNA linear amplification validated by gene expression analysis of human kidney cells using cDNA microarrays
    Michael Rudnicki
    Department of Nephrology, University Hospital of Innsbruck, Innsbruck, Austria
    Nephron Exp Nephrol 97:e86-95. 2004
  6. ncbi request reprint Neutrophil transmigration in renal proximal tubular LLC-PK1 cells
    Michael Joannidis
    Department of General Internal Medicine, University Hospital, Innsbruck, Austria
    Cell Physiol Biochem 14:101-12. 2004
  7. ncbi request reprint Effect of iron treatment on circulating cytokine levels in ESRD patients receiving recombinant human erythropoietin
    Gunter Weiss
    Department of Internal Medicine and Division of Nephrology, University Hospital of Innsbruck, Innsbruck, Austria
    Kidney Int 64:572-8. 2003
  8. ncbi request reprint Membranous nephropathy in a patient with hereditary complete complement C4 deficiency
    Karl Lhotta
    Division of Clinical Nephrology, Department of Internal Medicine, Innsbruck University Hospital, Anichstrasse 35, A 6020 Innsbruck, Austria
    Nephrol Dial Transplant 19:990-3. 2004
  9. ncbi request reprint Age and renal transplantation: an interim analysis
    Gabriele Schratzberger
    University Hospital, Department of Internal Medicine, Division of Nephrology, Innsbruck, Austria
    Nephrol Dial Transplant 18:471-6. 2003
  10. ncbi request reprint Proteinuria and hemoglobin levels in patients with primary glomerular disease
    Nina Mähr
    Division of Nephrology, Department of Medical Genetics, Molecular and Clinical Pharmacology, Innsbruck Medical University, Innsbruck, Austria
    Am J Kidney Dis 46:424-31. 2005

Collaborators

Detail Information

Publications50

  1. pmc Bloodstream infection following 217 consecutive systemic-enteric drained pancreas transplants
    Natalie Berger
    Department of General and Transplant Surgery, Medical University, Innsbruck, Austria
    BMC Infect Dis 6:127. 2006
    ..Combined kidney pancreas transplantation (PTx) evolved as excellent treatment for diabetic nephropathy. Infections remain common and serious complications...
  2. ncbi request reprint ACE genotype and ACE inhibitor response in kidney disease: a perspective
    Gert Mayer
    Division of Nephrology, University of Innsbruck, Austria
    Am J Kidney Dis 40:227-35. 2002
    ..Nonetheless, the rapidly evolving area of pharmacogenomics soon will also affect therapeutic decisions in the field of nephrology and hypertension...
  3. doi request reprint Markers of cellular senescence in zero hour biopsies predict outcome in renal transplantation
    Christian Koppelstaetter
    Division of Nephrology, Department of Internal Medicine, Medical University Innsbruck, Innsbruck, Austria
    Aging Cell 7:491-7. 2008
    ..We conclude that the molecular aging marker CDKN2A in combination with chronological donor age predict renal allograft function after 1 year significantly better than chronological donor age alone...
  4. ncbi request reprint Failure of BCL-2 up-regulation in proximal tubular epithelial cells of donor kidney biopsy specimens is associated with apoptosis and delayed graft function
    Christoph Schwarz
    Department of Internal Medicine III, Division of Nephrology, University of Vienna, Austria
    Lab Invest 82:941-8. 2002
    ..These data suggest that failure of proximal tubular cells to respond to injury by up-regulation of survival factors from the Bcl-2 family contributes to postischemic ARF in patients after cadaveric renal transplantation...
  5. ncbi request reprint Reliability of t7-based mRNA linear amplification validated by gene expression analysis of human kidney cells using cDNA microarrays
    Michael Rudnicki
    Department of Nephrology, University Hospital of Innsbruck, Innsbruck, Austria
    Nephron Exp Nephrol 97:e86-95. 2004
    ..868. These results indicate that linear amplification using RiboAmp kit yields amplified RNA with a high degree of linearity and reproducibility...
  6. ncbi request reprint Neutrophil transmigration in renal proximal tubular LLC-PK1 cells
    Michael Joannidis
    Department of General Internal Medicine, University Hospital, Innsbruck, Austria
    Cell Physiol Biochem 14:101-12. 2004
    ..The present study was performed to investigate whether incubation of tubular epithelia with cytokines or endotoxin (LPS) does stimulate adhesion and migration of leukocytes through these epithelia in vitro...
  7. ncbi request reprint Effect of iron treatment on circulating cytokine levels in ESRD patients receiving recombinant human erythropoietin
    Gunter Weiss
    Department of Internal Medicine and Division of Nephrology, University Hospital of Innsbruck, Innsbruck, Austria
    Kidney Int 64:572-8. 2003
    ..However, iron catalyzes the formation of toxic radicals, which might promote vascular damage, is a nutrient for microorganisms, and negatively affects immune pathways, thus increasing the risk for severe infections...
  8. ncbi request reprint Membranous nephropathy in a patient with hereditary complete complement C4 deficiency
    Karl Lhotta
    Division of Clinical Nephrology, Department of Internal Medicine, Innsbruck University Hospital, Anichstrasse 35, A 6020 Innsbruck, Austria
    Nephrol Dial Transplant 19:990-3. 2004
  9. ncbi request reprint Age and renal transplantation: an interim analysis
    Gabriele Schratzberger
    University Hospital, Department of Internal Medicine, Division of Nephrology, Innsbruck, Austria
    Nephrol Dial Transplant 18:471-6. 2003
  10. ncbi request reprint Proteinuria and hemoglobin levels in patients with primary glomerular disease
    Nina Mähr
    Division of Nephrology, Department of Medical Genetics, Molecular and Clinical Pharmacology, Innsbruck Medical University, Innsbruck, Austria
    Am J Kidney Dis 46:424-31. 2005
    ..Anemia in association with nephrotic syndrome has been described in small patient series and case reports. Whether nephrotic patients develop anemia has not been formally investigated...
  11. ncbi request reprint Effect of tissue fixatives on telomere length determination by quantitative PCR
    Christian Koppelstaetter
    Division of Nephrology, Department of Internal Medicine, Medical University Innsbruck, Anichstrasse 35, Innsbruck 6020, Austria
    Mech Ageing Dev 126:1331-3. 2005
    ..Unfortunately therefore, many easily accessible tissue samples from pathology laboratories are unsuitable for this technique...
  12. ncbi request reprint Cigarette smoking and vascular pathology in renal biopsies
    Karl Lhotta
    Clinical Nephrology Division, Department of Internal Medicine, Innsbruck University Hospital, Innsbruck, Austria
    Kidney Int 61:648-54. 2002
    ..The exact pathomechanism of nicotine-induced renal damage is, however, unknown. Autopsy studies and functional investigations suggest that the renal vasculature is primarily affected by smoking...
  13. ncbi request reprint Telomere length of in vivo expanded CD4(+)CD25 (+) regulatory T-cells is preserved in cancer patients
    Dominik Wolf
    Department of Hematology and Oncology, Innsbruck Medical University, Anichstr 35, 6020 Innsbruck, Austria
    Cancer Immunol Immunother 55:1198-208. 2006
    ..It remains unclear whether this is due to redistribution or active proliferation. The latter would require the upregulation of telomerase activity, whose regulation also remains unknown for Treg...
  14. ncbi request reprint Late referral defined by renal function: association with morbidity and mortality
    Karl Lhotta
    Division of Nephrology, Department of Internal Medicine, Innsbruck University Hospital, Innsbruck, Austria
    J Nephrol 16:855-61. 2003
    ..Many patients with chronic renal failure are referred very late to nephrology units. Late referral (LR) is reported to be associated with increased morbidity and mortality...
  15. ncbi request reprint Evaluation of the living kidney donor
    Hendrik Koller
    Division of Nephrology, Leopold Franzens University Innsbruck, Anichstrasse 35, A 6020 Innsbruck, Austria
    Nephrol Dial Transplant 19:iv41-4. 2004
    ..Such an approach, however, necessitates a post-donation follow-up programme to be offered...
  16. ncbi request reprint Oncostatin M-induced effects on EMT in human proximal tubular cells: differential role of ERK signaling
    Verena Pollack
    Division of Nephrology, Department of Internal Medicine, Innsbruck Medical University, Anichstrasse 35, A 6020 Innsbruck, Austria
    Am J Physiol Renal Physiol 293:F1714-26. 2007
    ..Furthermore, functional ERK1/2 signaling is necessary for basal claudin-2 expression...
  17. ncbi request reprint Regional variability in the incidence of end-stage renal disease: an epidemiological approach
    Florian Wimmer
    Division of Nephrology, Division of Clinical Epidemiology, Innsbruck University Hospital, Austria
    Nephrol Dial Transplant 18:1562-7. 2003
    ..Regional variability in the incidence of end-stage renal disease (ESRD) in Austria is reported. Our aim was to investigate the reason for low rates in the state of Tyrol...
  18. pmc Differential effects of rapamycin in anti-GBM glomerulonephritis
    Kathrin Hochegger
    Division of Nephrology, Tyrolean Cancer Research Institute, Innsbruck Medical University, Innsbruck, Austria
    J Am Soc Nephrol 19:1520-9. 2008
    ..Once disease is established, however, rapamycin seems to worsen glomerulonephritis by disturbing the endothelial cell/vascular endothelial growth factor system in the kidney...
  19. ncbi request reprint In vitro treatment of dendritic cells with tacrolimus: impaired T-cell activation and IP-10 expression
    Martin Tiefenthaler
    Department of Nephrology, University of Innsbruck, Innsbruck, Austria
    Nephrol Dial Transplant 19:553-60. 2004
    ..We used a therapeutic dose (2.4 x 10(-9 )M) of tacrolimus to investigate its effect on human monocyte-derived DC...
  20. ncbi request reprint Chronic allograft failure: a disease we don't understand and can't cure?
    Gabriele Schratzberger
    Division of Nephrology, Department of Internal Medicine, Anichstrasse 35, A 6020 Innsbruck, Austria
    Nephrol Dial Transplant 17:1384-90. 2002
  21. ncbi request reprint Antiproteinuric versus antihypertensive effects of high-dose ACE inhibitor therapy
    Martin Haas
    Department of Internal Medicine III, Division of Nephrology, University Vienna, Austria
    Am J Kidney Dis 40:458-63. 2002
    ..We conducted this study to determine whether an increase in ACE-inhibitor dose above the maximal antihypertensive effect has additional antiproteinuric potential...
  22. ncbi request reprint Genome-wide gene-expression patterns of donor kidney biopsies distinguish primary allograft function
    Peter Hauser
    Department of Nephrology, University of Vienna, Austria
    Lab Invest 84:353-61. 2004
    ..Thus, suppression of inflammation in the cadaveric donor might be a cheap and promising intervention for postischemic acute renal failure...
  23. ncbi request reprint Cigarette smoking and chronic allograft nephropathy
    Nina Zitt
    Clinical Division of Nephrology, Innsbruck Medical University, Anichstrasse 35, A 6020 Innsbruck, Austria
    Nephrol Dial Transplant 22:3034-9. 2007
    ..Smoking has been demonstrated to decrease patient and graft survival after kidney transplantation. Data on histological changes associated with smoking in renal allografts are lacking...
  24. ncbi request reprint ERK1/2-driven and MKP-mediated inhibition of EGF-induced ERK5 signaling in human proximal tubular cells
    Rita Sarközi
    Clinical Division of Nephrology, Department of Internal Medicine, Medical University of Innsbruck, Innsbruck, Austria
    J Cell Physiol 211:88-100. 2007
    ..These results suggest the existence of an ERK1/2-driven negative feed-back regulation of ERK5 signaling in EGF-stimulated HK-2 cells, which is mediated by MKP-3, DUSP5 and/or MKP-1...
  25. ncbi request reprint Gene-expression profiles and age of donor kidney biopsies obtained before transplantation distinguish medium term graft function
    Alexander Kainz
    Department of Nephrology, KH Elisabethinen Linz, and Medical University of Vienna, Vienna, Austria
    Transplantation 83:1048-54. 2007
    ..Donor factors such as age profoundly influence long-term graft function after cadaveric renal transplantation, but the molecular signature of these aspects in the allograft remains unknown...
  26. ncbi request reprint CD4+CD25+ regulatory T cells inhibit experimental anti-glomerular basement membrane glomerulonephritis in mice
    Dominik Wolf
    Clinical Division of Hematology and Oncology, Innsbruck Medical University, Anichstrasse 35, 6020 Innsbruck, Austria
    J Am Soc Nephrol 16:1360-70. 2005
    ..This report provides first evidence that Treg are potent suppressors of anti-GBM GN. Treg therefore might be of therapeutic value for the treatment of severe GN in humans...
  27. ncbi request reprint Apoptosis of human polymorphonuclear neutrophils accelerated by dialysis membranes via the activation of the complement system
    Hendrik Koller
    Medizinishe Universität Innsbruck, Universitatsklinik fur Innere Medizin, Klinische Abteilung für Nephrologie, Anichstrasse 35, A 6020 Innsbruck, Austria
    Nephrol Dial Transplant 19:3104-11. 2004
    ..The objective of this study was to study the effect of HD membranes on apoptosis induction in polymorphonuclear neutrophils (PMN)...
  28. ncbi request reprint Alterations in gene expression in cadaveric vs. live donor kidneys suggest impaired tubular counterbalance of oxidative stress at implantation
    Alexander Kainz
    Department of Nephrology, University of Vienna, Vienna, Austria
    Am J Transplant 4:1595-604. 2004
    ..These data suggest that CAD kidneys exhibit a distinctly different set of transcripts in the TI compartment but not in the G compartment when compared with LIV kidneys...
  29. ncbi request reprint [Remission of chronic kidney diseases. A realistic goal?]
    Gert Mayer
    Wien Klin Wochenschr 115:405-6. 2003
  30. ncbi request reprint Effects of microinjection of synthetic Bcl-2 domain peptides on apoptosis of renal tubular epithelial cells
    Elisabeth Peherstorfer
    Division of Nephrology and Dialysis, Department of Internal Medicine III, University of Vienna, A 1090 Vienna, Austria
    Am J Physiol Renal Physiol 283:F190-6. 2002
    ..Analogs to these regulatory peptides could therefore provide valuable lead compounds in the therapeutical context...
  31. ncbi request reprint One-year growth hormone therapy improves granulocyte function without major effects on nutritional and anthropometric parameters in malnourished hemodialysis patients
    Harald Kotzmann
    Division of Endocrinology and Metabolism, Department of Medicine III, University of Vienna, Austria
    Nephron Clin Pract 93:C75-82. 2003
    ..In short-term trials anabolic effects of rhGH therapy have been demonstrated in patients on chronic hemodialysis...
  32. ncbi request reprint Detrimental effects of controlled reperfusion on renal function after porcine autotransplantation are fully compensated by the use of Carolina rinse solution
    Peter Wamser
    Department of Surgery, University of Vienna, General Hospital, Wahringer Gurtel 18 20, 1090 Vienna, Austria
    Transpl Int 16:191-6. 2003
    ..The flushing of organs with CR prior to controlled reperfusion significantly improves ClCr as well as urine output...
  33. pmc Expression of granzyme A in human polymorphonuclear neutrophils
    Kathrin Hochegger
    Clinical Division of Nephrology, Innsbruck Medical University, Innsbruck, Austria
    Immunology 121:166-73. 2007
    ..In conclusion, we provide clear evidence that GzmA is constitutively expressed in human PMNs and can be up-regulated upon stimulation. These findings may also indicate a role for GzmA in PMNs in defence against invading pathogens...
  34. ncbi request reprint Regular physical exercise improves endothelial function in heart transplant recipients
    Alice Schmidt
    Department of Clinical Pharmacology, University of Vienna, Austria
    Clin Transplant 16:137-43. 2002
    ..We have studied whether endothelial function can be improved in HTX patients participating in a regular physical training program as demonstrated in patients with chronic heart failure, hypertension and coronary artery disease...
  35. ncbi request reprint Renal hemodynamic effects of somatostatin are not related to inhibition of endogenous insulin release
    Alice Schmidt
    Department of Clinical Pharmacology, Division of Nephrology and Dialysis, and Institute of Medical Physics, University of Vienna, Vienna, Austria
    Kidney Int 61:1788-93. 2002
    ..Since insulin can cause vasodilation, we hypothesized that removal of basal insulin release by somatostatin may contribute to somatostatin-induced renal vasoconstriction...
  36. ncbi request reprint Pharmacokinetic analysis of docetaxel during haemodialysis in a patient with locally advanced non-small cell lung cancer
    Kathrin Hochegger
    Nephrol Dial Transplant 22:289-90. 2007
  37. ncbi request reprint Role of alpha/beta and gamma/delta T cells in renal ischemia-reperfusion injury
    Kathrin Hochegger
    Clinical Division of Nephrology, Clinical Department of Internal Medicine, Innsbruck Medical University, Anichstrasse 35, A 6020 Innsbruck, Austria
    Am J Physiol Renal Physiol 293:F741-7. 2007
    ..This report provides further evidence that alpha/beta T cells are major effector cells in renal IRI, whereas gamma/delta T cells play a role as mediator cells in the first 72 h of renal IRI...
  38. ncbi request reprint Impact of ENPP1 genotype on arterial calcification in patients with end-stage renal failure
    Philipp Eller
    Department of Internal Medicine, Division of General Internal Medicine, Innsbruck Medical University, Innsbruck, Austria
    Nephrol Dial Transplant 23:321-7. 2008
    ..Inactivating mutations of ENPP1 are associated with generalized arterial calcification of infancy. We hypothesized the ENPP1 K121Q variant to be associated with increased vascular calcification in patients with end-stage renal failure...
  39. ncbi request reprint [Primary glomerulonephritis]
    Gabriele Schratzberger
    Klinische Abteilung für Nephrologie, Universitatsklinik fur Innere Medizin, Medizinische Universitat Innsbruck, Innsbruck, Osterreich
    Wien Klin Wochenschr 118:57-66; quiz 67. 2006
  40. ncbi request reprint p21 and mTERT are novel markers for determining different ischemic time periods in renal ischemia-reperfusion injury
    Kathrin Hochegger
    Innsbruck Medical University, Clinical Division of Nephrology, Anichstrasse 35, A 6020 Innsbruck, Austria
    Am J Physiol Renal Physiol 292:F762-8. 2007
    ..Taken together, we detected mTERT and p21 as "indicator" genes for short and long ischemic intervals, respectively. These two proteins might also be possible new therapeutic targets in the treatment and prevention of acute renal failure...
  41. ncbi request reprint Clearance of C4d deposition after successful treatment of acute humoral rejection in follow-up biopsies: a report of three cases
    Hendrik Koller
    Department of Nephrology, University Hospital of Innsbruck, Anichstrasse 35, 6020 Innsbruck, Austria
    Transpl Int 17:177-81. 2004
    ..We conclude that successful treatment of AHR is followed by complete resolution of serological and histological markers of AHR, displayed by the disappearance of C4d...
  42. ncbi request reprint Effects of 12 months of recombinant growth hormone therapy on parameters of bone metabolism and bone mineral density in patients on chronic hemodialysis
    Harald Kotzmann
    Division of Endocrinology and Metabolism, Department of Medicine III, Ludwig Boltzmann Institute for Experimental Endocrinology, University of Vienna, Vienna, Austria
    J Nephrol 17:87-94. 2004
    ....
  43. ncbi request reprint Effects of AT1 and AT2 receptor blockade on angiotensin II induced apoptosis of human renal proximal tubular epithelial cells
    Claudia Weidekamm
    Division of Nephrology and Dialysis, Department of Internal Medicine III, University of Vienna
    Wien Klin Wochenschr 114:725-9. 2002
    ....
  44. ncbi request reprint The immunomodulator FTY720 interferes with effector functions of human monocyte-derived dendritic cells
    Hansgeorg Muller
    Department of Nephrology, Innsbruck Medical School, Innsbruck, Austria
    Eur J Immunol 35:533-45. 2005
    ..This might represent a new aspect of the overall immunosuppressive action of FTY720 and makes DC potential targets of further sphingolipid-derived drugs...
  45. ncbi request reprint Role of mast cells in experimental anti-glomerular basement membrane glomerulonephritis
    Kathrin Hochegger
    Innsbruck Medical University, Clinical Division of Nephrology, Innsbruck, Austria
    Eur J Immunol 35:3074-82. 2005
    ..Our report provides the first direct evidence that MC are protective in anti-GBM GN, possibly by modulating the influx of effector T cells and macrophages to inflammatory sites in the kidney...
  46. ncbi request reprint Detection of coregulation in differential gene expression profiles
    Paul Perco
    Institute for Biomolecular Structural Chemistry, University of Vienna, Campus Vienna Biocenter 6, 1030 Vienna, Austria
    Biosystems 82:235-47. 2005
    ....
  47. ncbi request reprint Eurotransplant kidney allocation system (ETKAS): rationale and implementation
    Gert Mayer
    Nephrol Dial Transplant 21:2-3. 2006
  48. ncbi request reprint Antioxidant treatment of therapy-resistant idiopathic membranous nephropathy with probucol: a pilot study
    Martin Haas
    Division of Nephrology and Dialysis, University of Vienna, Austria
    Wien Klin Wochenschr 114:143-7. 2002
    ..Since the pathophysiology might be similar to idiopathic membranous nephropathy in humans, we performed a prospective multicenter trial to investigate the efficacy of the lipid peroxidation scavenger, probucol...
  49. ncbi request reprint Antioxidant therapy in glomerular disease
    Martin Haas
    Wien Klin Wochenschr 114:138-40. 2002
  50. doi request reprint An update on the relationship between the kidney, salt and hypertension
    Gert Mayer
    Division of Nephrology and Hypertensiology, Department of Internal Medicine IV, Innsbruck, Austria
    Wien Med Wochenschr 158:365-9. 2008
    ..As a conclusion, we have to remember that an elevation of arterial pressure can only be maintained if renal function as indicated by pressure natriuresis is impaired...