J Marksteiner

Summary

Affiliation: University of Innsbruck
Country: Austria

Publications

  1. ncbi request reprint Synaptic proteins in Alzheimer's disease
    Josef Marksteiner
    Institute for Biochemical Pharmacology, Department of Psychiatry, University Innsbruck, Austria
    J Mol Neurosci 18:53-63. 2002
  2. ncbi request reprint Cerebrovascular damage as a cause for Alzheimer's disease
    Christian Humpel
    Laboratory of Exp Alzheimer s Research, Department of Psychiatry, Innsbruck Medical University, Austria
    Curr Neurovasc Res 2:341-7. 2005
  3. ncbi request reprint Treatment strategies in Alzheimer's disease with a focus on early pharmacological interventions
    Josef Marksteiner
    Department of Psychiatry, Medical University Innsbruck, Innsbruck, Austria
    Drugs Aging 21:415-26. 2004
  4. ncbi request reprint Distribution of chromogranin B-like immunoreactivity in the human hippocampus and its changes in Alzheimer's disease
    J Marksteiner
    Department of Psychiatry, University of Innsbruck, Austria
    Acta Neuropathol 100:205-12. 2000
  5. ncbi request reprint Differential regulation of chromogranin A, chromogranin B and secretogranin II in rat brain by phencyclidine treatment
    J Marksteiner
    Department of Psychiatry, University of Innsbruck, A 6020, Innsbruck, Austria
    Neuroscience 104:325-33. 2001
  6. ncbi request reprint [Alcohol-induced cognitive disorder: alcohol dementia]
    J Marksteiner
    Universitätsklinik für Psychiatrie, Anichstrasse 35, A 6020 Innsbruck
    Wien Med Wochenschr 152:98-101. 2002
  7. ncbi request reprint Glial-cell-line-derived neurotrophic factor enhances biosynthesis of substance P in striatal neurons in vitro
    C Humpel
    Neurochemical Unit, Department of Psychiatry, University Hospital Innsbruck, Anichstrasse 35, A 6020 Innsbruck, Austria
    Cell Tissue Res 286:249-55. 1996
  8. doi request reprint Chromogranin peptides in amyotrophic lateral sclerosis
    A Schrott-Fischer
    Department of Otolaryngology, Medical University of Innsbruck, A 6020 Innsbruck, Austria
    Regul Pept 152:13-21. 2009
  9. ncbi request reprint Cognitive impairment: assessment with brain magnetic resonance imaging and proton magnetic resonance spectroscopy
    Ulrike Weiss
    Department of Psychiatry, University of Innsbruck, Austria
    J Clin Psychiatry 64:235-42. 2003
  10. ncbi request reprint First localization and biochemical identification of chromogranin B- and secretoneurin-like immunoreactivity in the fetal human vagal/nucleus solitary complex
    M Bitsche
    Department of Otolaryngology, Medical University of Innsbruck, A 6020 Innsbruck, Austria
    Regul Pept 134:97-104. 2006

Collaborators

Detail Information

Publications57

  1. ncbi request reprint Synaptic proteins in Alzheimer's disease
    Josef Marksteiner
    Institute for Biochemical Pharmacology, Department of Psychiatry, University Innsbruck, Austria
    J Mol Neurosci 18:53-63. 2002
    ..Thee are particularly suitable to study nerve fibers, terminating at the inner molecular layer of the dentate gyrus. Chromogranin peptides have a potential as neuronal markers for synaptic degeneration in Alzheimer's disease...
  2. ncbi request reprint Cerebrovascular damage as a cause for Alzheimer's disease
    Christian Humpel
    Laboratory of Exp Alzheimer s Research, Department of Psychiatry, Innsbruck Medical University, Austria
    Curr Neurovasc Res 2:341-7. 2005
    ..An overlap with other forms of cognitive impairment, such as mild cognitive impairment, or vascular dementia will be discussed...
  3. ncbi request reprint Treatment strategies in Alzheimer's disease with a focus on early pharmacological interventions
    Josef Marksteiner
    Department of Psychiatry, Medical University Innsbruck, Innsbruck, Austria
    Drugs Aging 21:415-26. 2004
    ..No disease-modifying strategy can presently be offered to patients; however, given the pace of recent research there is optimism that slowing progression of Alzheimer's disease will soon be possible...
  4. ncbi request reprint Distribution of chromogranin B-like immunoreactivity in the human hippocampus and its changes in Alzheimer's disease
    J Marksteiner
    Department of Psychiatry, University of Innsbruck, Austria
    Acta Neuropathol 100:205-12. 2000
    ..It is particularly suitable for studying nerve fibers terminating at the inner molecular layer of the dentate gyrus. It is present in neuritic plaques, and its density is reduced in a layer-specific manner...
  5. ncbi request reprint Differential regulation of chromogranin A, chromogranin B and secretogranin II in rat brain by phencyclidine treatment
    J Marksteiner
    Department of Psychiatry, University of Innsbruck, A 6020, Innsbruck, Austria
    Neuroscience 104:325-33. 2001
    ..From these results we suggest that phencyclidine may induce synaptic alterations in specific brain areas and may contribute to a better understanding of synaptic dysfunction which may also occur in schizophrenia...
  6. ncbi request reprint [Alcohol-induced cognitive disorder: alcohol dementia]
    J Marksteiner
    Universitätsklinik für Psychiatrie, Anichstrasse 35, A 6020 Innsbruck
    Wien Med Wochenschr 152:98-101. 2002
    ..Some evidence is provided that nootropics might be of benefit. Alcohol abstinence is a most important step. Psychosocial interventions are essential to support the patients in their daily activities...
  7. ncbi request reprint Glial-cell-line-derived neurotrophic factor enhances biosynthesis of substance P in striatal neurons in vitro
    C Humpel
    Neurochemical Unit, Department of Psychiatry, University Hospital Innsbruck, Anichstrasse 35, A 6020 Innsbruck, Austria
    Cell Tissue Res 286:249-55. 1996
    ..This adds a previously unknown role to those that have been established for GDNF in the nigrostriatal system...
  8. doi request reprint Chromogranin peptides in amyotrophic lateral sclerosis
    A Schrott-Fischer
    Department of Otolaryngology, Medical University of Innsbruck, A 6020 Innsbruck, Austria
    Regul Pept 152:13-21. 2009
    ..The intracellular co-occurrence of superoxide dismutase 1 and chromogranins may suggest a functional interaction between these proteins. This study should prompt further experiments to elucidate the role of chromogranins in ALS patients...
  9. ncbi request reprint Cognitive impairment: assessment with brain magnetic resonance imaging and proton magnetic resonance spectroscopy
    Ulrike Weiss
    Department of Psychiatry, University of Innsbruck, Austria
    J Clin Psychiatry 64:235-42. 2003
    ..This study was designed to evaluate its role in routine application to reveal the diagnostic reasons for cognitive impairment...
  10. ncbi request reprint First localization and biochemical identification of chromogranin B- and secretoneurin-like immunoreactivity in the fetal human vagal/nucleus solitary complex
    M Bitsche
    Department of Otolaryngology, Medical University of Innsbruck, A 6020 Innsbruck, Austria
    Regul Pept 134:97-104. 2006
    ..These results demonstrate that each chromogranin peptide is expressed during human fetal life in neurons of the vagal/nucleus solitary complex indicating that these peptides could be important during prenatal development...
  11. ncbi request reprint Cerebrospinal fluid biomarkers for diagnosis of Alzheimer's disease: beta-amyloid(1-42), tau, phospho-tau-181 and total protein
    Josef Marksteiner
    Department of General Psychiatry, Innsbruck Medical University, Innsbruck, Austria
    Drugs Today (Barc) 43:423-31. 2007
    ..This article reviews the use of CSF biomarkers and of putative blood-related markers...
  12. doi request reprint Impairment in emotion recognition abilities in patients with mild cognitive impairment, early and moderate Alzheimer disease compared with healthy comparison subjects
    Elisabeth M Weiss
    Department of General Psychiatry, Innsbruck Medical University, Innsbruck, Austria
    Am J Geriatr Psychiatry 16:974-80. 2008
    ..To investigate emotion discrimination abilities in healthy comparison subjects, patients with mild cognitive impairment (MCI), early and moderate Alzheimer disease (AD)...
  13. ncbi request reprint Chromogranin peptides in Alzheimer's disease
    Theresa Lechner
    Department of Psychiatry, Anichstrasse 35, Innsbruck A 6020, Austria
    Exp Gerontol 39:101-13. 2004
    ..Chromogranin A is likely to be a mediator between neuronal, glial and inflammatory mechanisms found in Alzheimer disease...
  14. ncbi request reprint Beta-amyloid expression, release and extracellular deposition in aged rat brain slices
    J Marksteiner
    Laboratory of Psychiatry and Exp Alzheimer s Research, Department of General Psychiatry, Innsbruck Medical University, Innsbruck, Austria
    Mol Psychiatry 13:939-52. 2008
    ..This novel in vitro model may enable us to investigate further the pathological cascade for AD and may be useful to explore future therapeutics...
  15. ncbi request reprint Distribution of catestatin-like immunoreactivity in the human auditory system
    M Bitsche
    Department of Otolaryngology, University of Innsbruck, Anichstrasse 35, A 6020 Innsbruck, Austria
    Hear Res 184:16-26. 2003
    ..Further studies should elucidate a possible interaction with other neurotransmitters in the auditory system...
  16. ncbi request reprint [Gender differences in cognitive functions]
    E M Weiss
    Universitätsklinik für Psychiatrie, Abteilung für Allgemeine Psychiatrie, Medizinische Universitat Innsbruck, Osterreich
    Fortschr Neurol Psychiatr 73:587-95. 2005
    ..Furthermore we summarize the results from functional MRI experiments, which is a useful tool for noninvasively localizing areas in the brain involved in specific cognitive functions...
  17. ncbi request reprint Striatal dopamine transporter function in dementia with Lewy bodies and Parkinson's disease
    G Ransmayr
    Department of Neurology, University Hospital Innsbruck, Austria
    Eur J Nucl Med 28:1523-8. 2001
    ..Whether these findings are helpful in the differential diagnosis of DLB and PD needs to be examined in further studies...
  18. ncbi request reprint Diagnostic value of fine motor deficits in patients with low-grade hepatic encephalopathy
    Sergei Mechtcheriakov
    Department of General Psychiatry, Medical University Innsbruck, Anichstrasse 35, A 6020 Innsbruck, Austria
    World J Gastroenterol 11:2777-80. 2005
    ..We performed a pilot study to comparatively investigate the kinematic characteristics of small and large rapid alternating movements in patients with liver cirrhosis and low-grade hepatic encephalopathy...
  19. ncbi request reprint Motor dysfunction in patients with liver cirrhosis: impairment of handwriting
    Sergei Mechtcheriakov
    Department of General Psychiatry, Medical University Innsbruck, Anichstrasse 35, 6020, Innsbruck, Austria
    J Neurol 253:349-56. 2006
    ..Our findings suggest the application of kinematic analysis of handwriting for diagnostics of motor dysfunction in patients with mild forms of hepatic encephalopathy...
  20. ncbi request reprint Measurement of thirteen biological markers in CSF of patients with Alzheimer's disease and other dementias
    Imrich Blasko
    Department of Psychiatry, Innsbruck Medical University, Innsbruck, Austria
    Dement Geriatr Cogn Disord 21:9-15. 2006
    ..It is suggested that the increase in NGF depends on the extent of neurodegeneration of the AD type and the increase in MCP-1 on age...
  21. ncbi request reprint Multidimensional assessment of neuro-psychiatric symptoms in patients with low-grade hepatic encephalopathy: a clinical rating scale
    Sergei Mechtcheriakov
    Department of General Psychiatry, Medical University Innsbruck, Austria
    World J Gastroenterol 11:5893-8. 2005
    ..To evaluate the feasibility of a new clinical rating scale for a standardized assessment of cirrhosis-associated neuro-psychiatric symptoms...
  22. ncbi request reprint Basal forebrain atrophy is a distinctive pattern in dementia with Lewy bodies
    Christian Brenneis
    Department of Neurology, University Hospital of Innsbruck, Anichstr 35, 6020 Innsbruck, Austria
    Neuroreport 15:1711-4. 2004
    ..Atrophy of insular cortex was found in both patient groups...
  23. ncbi request reprint Chemical shift magnetic resonance spectroscopy of cingulate grey matter in patients with minimal hepatic encephalopathy
    Sergei Mechtcheriakov
    Department of General Psychiatry, Innsbruck Medical University, Anichstrasse 35, 6020 Innsbruck, Austria
    Neuroradiology 47:27-34. 2005
    ....
  24. ncbi request reprint Catestatin--a novel neuropeptide in carcinoid tumors of the appendix
    Rupert Prommegger
    Department of Surgery, University of Innsbruck, Austria
    Anticancer Res 24:311-6. 2004
    ..Catestatin, a novel 21 amino acid neuropeptide derived from chromogranin A, was determined immunohistochemically in 30 carcinoid tumors of the appendix and various carcinoid tumors of other localities...
  25. ncbi request reprint Incomplete improvement of visuo-motor deficits in patients with minimal hepatic encephalopathy after liver transplantation
    Sergei Mechtcheriakov
    Department of General Psychiatry, University of Innsbruck, Innsbruck, Austria
    Liver Transpl 10:77-83. 2004
    ..We concluded that monitoring of cognitive and visuo-motor functioning is important for the post-transplant rehabilitation of patients with liver cirrhosis...
  26. ncbi request reprint Cognitive deterioration in Alzheimer's disease is accompanied by increase of plasma neopterin
    Imrich Blasko
    Department of Psychiatry, Innsbruck Medical University, Anichstrasse 35, A 6020 Innsbruck, Tyrol, Austria
    J Psychiatr Res 41:694-701. 2007
    ..In summary, neopterin concentrations correlated with cognitive decline in AD patients, which might be due to high CMV seropositivity in that population...
  27. doi request reprint Analysis of cerebrospinal fluid of Alzheimer patients. Biomarkers and toxic properties
    Josef Marksteiner
    Department of General Psychiatry, Innsbruck Medical University, Innsbruck, Austria
    Pharmacology 82:214-20. 2008
    ..We conclude that in CSF of AD patients (at least partly) mature NGF-like immunoreactivity is enhanced, and is masked in a bioassay by the toxic properties of CSF...
  28. pmc A widespread distinct pattern of cerebral atrophy in patients with alcohol addiction revealed by voxel-based morphometry
    Sergei Mechtcheriakov
    Department of General Psychiatry, Medical University Innsbruck, Anichstrasse 35, A 6020 Innsbruck, Austria
    J Neurol Neurosurg Psychiatry 78:610-4. 2007
    ..The complexity of these brain alterations suggests that several brain areas are involved, although the definition of the brain alteration patterns is not yet accomplished...
  29. ncbi request reprint Persistent cognitive deficits associated with lithium intoxication: a neuropsychological case description
    Lisa Bartha
    University Clinic of Neurology, Innsbruck, Austria
    Cortex 38:743-52. 2002
    ..Different from other case studies our findings suggest that lithium intoxication may cause a combined, multifocal functional impairment of subcortical and cortical neural mechanisms in both hemispheres...
  30. ncbi request reprint Differential effect of catechol-O-methyltransferase Val158Met genotype on emotional recognition abilities in healthy men and women
    Elisabeth M Weiss
    Department of General Psychiatry, Innsbruck Medical, Innsbruck, Austria
    J Int Neuropsychol Soc 13:881-7. 2007
    ..Additional research is needed to further define the neurocognitive phenotypes associated with COMT polymorphisms...
  31. ncbi request reprint Influence of age and gender on risperidone plasma concentrations
    Wolfgang Aichhorn
    Department of Psychiatry, Innsbruck Medical University, Innsbruck, Austria
    J Psychopharmacol 19:395-401. 2005
    ..This linear increase (over 30% per decade) may then lead to an increased incidence of adverse effects in elderly patients...
  32. ncbi request reprint [Psychosocial therapy of patients with dementia]
    P Gurka
    Universitätsklinik für Psychiatrie, Anichstrasse 35, A 6020 Innsbruck
    Wien Med Wochenschr 152:102-6. 2002
    ..Thus they should be considered to be an integral part of a comprehensive therapeutic approach to dementia patients and their families...
  33. ncbi request reprint Nerve growth factor and glial cell line-derived neurotrophic factor restore the cholinergic neuronal phenotype in organotypic brain slices of the basal nucleus of Meynert
    C Weis
    Department of Psychiatry, University Hospital Innsbruck, Anichstr. 35, A-6020, Innsbruck, Austria
    Neuroscience 102:129-38. 2001
    ..In conclusion, it is shown that, in the axotomized organotypic slice model, the number of cholinergic neurons is decreased, but can be partly restored by nerve growth factor and glial cell line-derived neurotrophic factor...
  34. ncbi request reprint Localization and expression of substance P in transgenic mice overexpressing human APP751 with the London (V717I) and Swedish (K670M/N671L) mutations
    Michael Willis
    Department of General Psychiatry, Medical University Innsbruck, Anichstrasse 35, A 6020 Innsbruck, Austria
    Brain Res 1143:199-207. 2007
    ..Future experiments including substance P antagonists are necessary to further explore the interaction between beta-amyloid deposits and substance P...
  35. doi request reprint Pattern of brain atrophy in elderly patients with depression revealed by voxel-based morphometry
    Karl Egger
    Department of Radiology, Medical University Innsbruck, Anichstrasse 35, A 6020 Innsbruck, Austria
    Psychiatry Res 164:237-44. 2008
    ..Furthermore, our results may not be generalizable across depression severity or to hospitalized patients. The findings are consistent with our hypothesis that depression in the elderly is associated with local gray matter dysfunction...
  36. ncbi request reprint Chromogranin B and Secretogranin II in transgenic mice overexpressing human APP751 with the London (V717I) and Swedish (K670M/N671L) mutations and in Alzheimer patients
    Michael Willis
    Department of General Psychiatry, Medical University Innsbruck, Anichstrasse 35, 6020 Innsbruck, Austria
    J Alzheimers Dis 13:123-35. 2008
    ..Therefore specific changes of chromogranin peptides observed in Alzheimer patients can be related to amyloid-beta pathology only...
  37. ncbi request reprint Differential effects of phencyclidine application on secretogranin II expression in organotypic slices of rat prefrontal cortex
    Josef K Hinterhoelzl
    Department of General Psychiatry, University of Innsbruck, Innsbruck, Austria
    J Neurochem 87:13-21. 2003
    ..These results demonstrate that PCP modulates sg II expression in PFC tissue in the absence of afferent inputs and that the nature of these changes is dependent upon the duration of exposure to and/or withdrawal from PCP...
  38. ncbi request reprint Clock drawing, clock reading, clock setting, and judgment of clock faces in elderly people with dementia and depression
    Thomas Bodner
    Department of Biological Psychiatry, Innsbruck University Clinics, Innsbruck, Austria
    J Am Geriatr Soc 52:1146-50. 2004
    ..To assess patient performance on different clock tasks...
  39. ncbi request reprint Efficacy of donepezil treatment in Alzheimer patients with and without subcortical vascular lesions
    Imrich Blasko
    Department of Psychiatry, University Hospital of Innsbruck, Austria
    Pharmacology 72:1-5. 2004
    ..These data support previous observations that donepezil therapy is effective in AD patients with and without subcortical vascular lesions...
  40. ncbi request reprint Co-distribution patterns of chromogranin B-like immunoreactivity with chromogranin A and secretoneurin within the human brainstem
    A Kato
    Department of Otolaryngology, University of Innsbruck, Austria
    Brain Res 852:444-52. 2000
    ..These findings may provide a framework for future research in revealing a functional role of chromogranin peptides in the human brainstem...
  41. pmc Subacute dementia and imaging correlates in a case of Fahr's disease
    T Benke
    University Clinic of Neurology, Innsbruck, Austria
    J Neurol Neurosurg Psychiatry 75:1163-5. 2004
    ..This case indicates that FD may cause exclusively behavioural alterations and that the associated hypometabolism in certain frontal areas is closely related to the clinical picture...
  42. ncbi request reprint Pharmacological treatment strategies of residential primary care providers in dementia diseases--results of a representative survey in western Austria
    P Gurka
    Department of Psychiatry, Anichstrasse 35, 6020 Innsbruck, Austria
    Pharmacopsychiatry 35:144-9. 2002
    ..The goal of this study was to investigate pharmacological treatment strategies used by residential primary care providers for patients with dementia...
  43. doi request reprint An fMRI study of the numerical Stroop task in individuals with and without minimal cognitive impairment
    Liane Kaufmann
    Innsbruck Medical University, Clinical Department of Paediatrics IV, Division of Neuropediatrics, Innsbruck, Austria
    Cortex 44:1248-55. 2008
    ..To summarize, though MCI patients needed to recruit more distributed activation patterns conjunction analysis revealed common activation sites in response to magnitude processing and interference control...
  44. ncbi request reprint Reduction of chromogranin B-like immunoreactivity in distinct subregions of the hippocampus from individuals with schizophrenia
    Clara Nowakowski
    Department of Psychiatry, University of Innsbruck, Anichstrasse 35, 6020 Innsbruck, Austria
    Schizophr Res 58:43-53. 2002
    ..The loss of presynaptic proteins involved in distinct steps of exocytosis may cause complex synaptic disturbances in specific hippocampal subregions resulting in an imbalanced neurotransmitter availability in schizophrenic patients...
  45. doi request reprint Dkk-3 is elevated in CSF and plasma of Alzheimer's disease patients
    Christoph Zenzmaier
    Institute for Biomedical Aging Research, Innsbruck, Austria
    J Neurochem 110:653-61. 2009
    ..In summary, our data indicate that elevated Dkk-3 levels are specifically associated with AD and might serve as a potential non-invasive AD biomarker in plasma...
  46. doi request reprint Monocyte migration: a novel effect and signaling pathways of catestatin
    Margot Egger
    Department of Internal Medicine 1, Medical University of Innsbruck, Innsbruck, Austria
    Eur J Pharmacol 598:104-11. 2008
    ..In summary, our data indicate that catestatin induces monocyte chemotaxis by activation of a variety of signal transduction pathways suggesting a role of this peptide as an inflammatory cytokine...
  47. ncbi request reprint Influence of age, gender, body weight and valproate comedication on quetiapine plasma concentrations
    Wolfgang Aichhorn
    Department of General Psychiatry bDivision of Neurochemistry, Medical University Innsbruck, Austria
    Int Clin Psychopharmacol 21:81-5. 2006
    ..016). In conclusion, older age, body weight and comedication with valproate have to be considered when prescribing quetiapine. Higher plasma levels in female patients need to be replicated in larger samples...
  48. ncbi request reprint Direct molecular haplotyping of multiple polymorphisms within exon 4 of the human catechol-O-methyltransferase gene by liquid chromatography-electrospray ionization time-of-flight mass spectrometry
    Herbert Oberacher
    Institute of Legal Medicine, Innsbruck Medical University, Muellerstrasse 44, 6020, Innsbruck, Austria
    Anal Bioanal Chem 386:83-91. 2006
    ....
  49. ncbi request reprint Management of patients with cognitive impairment by residential doctors
    Peter Gurka
    Department of Psychiatry, Anichstrasse 35, A 2060 Innsbruck, Austria
    Int J Geriatr Psychiatry 17:290-1. 2002
  50. ncbi request reprint Glial cell line-derived neurotrophic factor enhances survival of GM-CSF dependent rat GMIR1-microglial cells
    Kayvon Salimi
    Laboratory of Psychiatry, Department of Psychiatry, University of Innsbruck, Anichstrasse 35, Austria
    Neurosci Res 43:221-9. 2002
    ..Inhibition of cAMP/cGMP dependent protein kinase enhanced the GDNF-induced GMIR1 cell number. The results suggest that GDNF has synergistic survival promoting effects on microglia potentially via autocrine mechanisms...
  51. ncbi request reprint Second-generation antipsychotics: is there evidence for sex differences in pharmacokinetic and adverse effect profiles?
    Wolfgang Aichhorn
    Department of General Psychiatry, Medical University Innsbruck, Innsbruck, Austria
    Drug Saf 29:587-98. 2006
    ..Data that are more specific will help determine the extent to which these differences will have implications for clinical management...
  52. ncbi request reprint Effects of age and sex on olanzapine plasma concentrations
    Ulrike Weiss
    Department of General Psychiatry, Medical University Innsbruck, Innsbruck, Austria
    J Clin Psychopharmacol 25:570-4. 2005
    ..All results were adjusted for smoking. Comedication did not significantly influence these results. In conclusion, age and sex are important variables to consider when prescribing olanzapine for women and in the elderly...
  53. doi request reprint L-type calcium channel CaV 1.2 in transgenic mice overexpressing human AbetaPP751 with the London (V717I) and Swedish (K670M/N671L) mutations
    Michael Willis
    Department of Psychiatry and Psychotherapy, University Clinic of General and Social Psychiatry, Innsbruck Medical University, Innsbruck, Austria
    J Alzheimers Dis 20:1167-80. 2010
    ..Further studies should clarify which functional implications are associated with the higher availability of CaV1.2 channels in late stage Alzheimer's disease...
  54. ncbi request reprint Age and gender effects on olanzapine and risperidone plasma concentrations in children and adolescents
    Wolfgang Aichhorn
    Department of Psychiatry and Psychotherapy, Private Medical University Salzburg, Ignaz Harrer Strasse 79, Salzburg, Austria
    J Child Adolesc Psychopharmacol 17:665-74. 2007
    ..So far, little is known about plasma concentrations and concentration-to-dose (C/D) ratios of these agents in children and adolescents compared to adults...
  55. ncbi request reprint Compartmentation of alpha 1 and alpha 2 GABA(A) receptor subunits within rat extended amygdala: implications for benzodiazepine action
    Walter A Kaufmann
    Centre for Molecular Biology and Neuroscience, Department of Anatomy, University of Oslo, N 0317 Oslo, Norway
    Brain Res 964:91-9. 2003
    ..It is concluded that the alpha1 and alpha2 subunits are differentially expressed within the extended amygdala, indicating that this structure is compartmentalized with respect to function and benzodiazepine action...
  56. ncbi request reprint Effects of acidosis on brain capillary endothelial cells and cholinergic neurons: relevance to vascular dementia and Alzheimer's disease
    Michael Pirchl
    Laboratory of Experimental Alzheimer s Research, Department of General Psychiatry, Innsbruck Medical University, Austria
    Neurol Res 28:657-64. 2006
    ..Acidosis may play an important role in the development of vascular dementia and Alzheimer's disease...
  57. ncbi request reprint [Sex differences in Alzheimer's disease]
    Reinhold Schmidt
    Univ Klinik für Neurologie, Medizinische Universitat Graz
    Neuropsychiatr 22:1-15. 2008
    ..Care takes place in 80% by the families and is provided by women in 78%. The rate of female care-givers in partly institutionalized care units in 91% in nursing homes it is 84%...