R Likar

Summary

Affiliation: University of Vienna
Country: Austria

Publications

  1. doi request reprint Comparable analgesic efficacy of transdermal buprenorphine in patients over and under 65 years of age
    Rudolf Likar
    Zentrum für interdisziplinäre Schmerz und Palliativmedizin, des Landeskrankenhaus Kärnten, Klagenfurt, Austria
    Clin J Pain 24:536-43. 2008
  2. ncbi request reprint Equipotent doses of transdermal fentanyl and transdermal buprenorphine in patients with cancer and noncancer pain: results of a retrospective cohort study
    Reinhard Sittl
    Pain Clinic, University of Erlangen, Erlangen, Germany
    Clin Ther 27:225-37. 2005
  3. ncbi request reprint Transdermal buprenorphine for treating nociceptive and neuropathic pain: four case studies
    Rudolf Likar
    Pain Clinic, General Hospital Klagenfurt, St Veither Strasse 47, 9026 Klagenfurt, Austria
    Anesth Analg 100:781-5, table of contents. 2005
  4. ncbi request reprint Long-term management of chronic pain with transdermal buprenorphine: a multicenter, open-label, follow-up study in patients from three short-term clinical trials
    Rudolf Likar
    Pain Clinic, General Hospital Klagenfurt, Klagenfurt, Austria, and Pain Clinic, University of Erlangen Nurnberg, Germany
    Clin Ther 28:943-52. 2006
  5. ncbi request reprint [Importance of intrathecal pain therapy]
    R Likar
    Landeskrankenhaus, Klagenfurt
    Schmerz 21:15-8, 20-4, 26-7. 2007
  6. ncbi request reprint Pharmacokinetic and pharmacodynamic properties of tramadol IR and SR in elderly patients: a prospective, age-group-controlled study
    Rudolf Likar
    Interdisciplinary Pain Clinic, General Hospital Klagen furt, Klagen furt, Austria
    Clin Ther 28:2022-39. 2006
  7. doi request reprint Challenging the equipotency calculation for transdermal buprenorphine: four case studies
    R Likar
    Pain Clinic, General Hospital Klagenfurt, Klagenfurt, Austria
    Int J Clin Pract 62:152-6. 2008
  8. ncbi request reprint Transdermal buprenorphine patches applied in a 4-day regimen versus a 3-day regimen: a single-site, Phase III, randomized, open-label, crossover comparison
    Rudolf Likar
    Interdisciplinary Pain Clinic, General Hospital Klagenfurt, Klagenfurt, Austria
    Clin Ther 29:1591-606. 2007
  9. ncbi request reprint [Topical application of local anesthetics and opioids after elective tooth extraction]
    R Likar
    Abteilung für Anästhesiologie und Allgemeine Intensivmedizin, LKH Klagenfurt, Osterreich
    Schmerz 19:195-8, 200. 2005
  10. doi request reprint [Comparison of the peripheral and central effects of opiates after iliac crest transplants. Reconstruction of severely atrophied maxilla]
    A S Virnik
    Abteilung für Mund, Kiefer und Gesichtschirurgie, Landeskrankenhaus Klagenfurt, Klagenfurt, Osterreich
    Schmerz 23:259-62, 264-6. 2009

Collaborators

Detail Information

Publications42

  1. doi request reprint Comparable analgesic efficacy of transdermal buprenorphine in patients over and under 65 years of age
    Rudolf Likar
    Zentrum für interdisziplinäre Schmerz und Palliativmedizin, des Landeskrankenhaus Kärnten, Klagenfurt, Austria
    Clin J Pain 24:536-43. 2008
    ..To compare the efficacy and tolerability of transdermal buprenorphine in elderly patients and 2 younger populations, all requiring analgesic treatment for moderate-to-severe chronic pain...
  2. ncbi request reprint Equipotent doses of transdermal fentanyl and transdermal buprenorphine in patients with cancer and noncancer pain: results of a retrospective cohort study
    Reinhard Sittl
    Pain Clinic, University of Erlangen, Erlangen, Germany
    Clin Ther 27:225-37. 2005
    ..Growing evidence from clinical practice, in which much lower doses of buprenorphine are used, suggests that this conversion ratio may be too high...
  3. ncbi request reprint Transdermal buprenorphine for treating nociceptive and neuropathic pain: four case studies
    Rudolf Likar
    Pain Clinic, General Hospital Klagenfurt, St Veither Strasse 47, 9026 Klagenfurt, Austria
    Anesth Analg 100:781-5, table of contents. 2005
    ..In each case, sufficient pain relief was obtained and no problems were encountered in switching from prior analgesic therapy with larger doses of other opioids...
  4. ncbi request reprint Long-term management of chronic pain with transdermal buprenorphine: a multicenter, open-label, follow-up study in patients from three short-term clinical trials
    Rudolf Likar
    Pain Clinic, General Hospital Klagenfurt, Klagenfurt, Austria, and Pain Clinic, University of Erlangen Nurnberg, Germany
    Clin Ther 28:943-52. 2006
    ..Long-term data are essential to determining the performance of an analgesic in the management of chronic pain...
  5. ncbi request reprint [Importance of intrathecal pain therapy]
    R Likar
    Landeskrankenhaus, Klagenfurt
    Schmerz 21:15-8, 20-4, 26-7. 2007
    ..Current practices for patient selection and management, screening, drug selection, dosing and implantation for intrathecal drug delivery systems are discussed...
  6. ncbi request reprint Pharmacokinetic and pharmacodynamic properties of tramadol IR and SR in elderly patients: a prospective, age-group-controlled study
    Rudolf Likar
    Interdisciplinary Pain Clinic, General Hospital Klagen furt, Klagen furt, Austria
    Clin Ther 28:2022-39. 2006
    ..Although age-related differences in pharmacologic responsiveness are to be expected, the pharmacodynamic and pharmacokinetic (PK) properties of tramadol have not been systematically compared between patients of various ages...
  7. doi request reprint Challenging the equipotency calculation for transdermal buprenorphine: four case studies
    R Likar
    Pain Clinic, General Hospital Klagenfurt, Klagenfurt, Austria
    Int J Clin Pract 62:152-6. 2008
    ..The aim of these case studies was to address the issue of opioid rotation or switching, raising the important issue of conversion ratios between different compounds and routes of administration...
  8. ncbi request reprint Transdermal buprenorphine patches applied in a 4-day regimen versus a 3-day regimen: a single-site, Phase III, randomized, open-label, crossover comparison
    Rudolf Likar
    Interdisciplinary Pain Clinic, General Hospital Klagenfurt, Klagenfurt, Austria
    Clin Ther 29:1591-606. 2007
    ..The primary recommendation contained in the prescribing information was that transdermal patches be worn for a 3-day period before application of a new patch...
  9. ncbi request reprint [Topical application of local anesthetics and opioids after elective tooth extraction]
    R Likar
    Abteilung für Anästhesiologie und Allgemeine Intensivmedizin, LKH Klagenfurt, Osterreich
    Schmerz 19:195-8, 200. 2005
    ..Since the patients presented in a pain-free state at the time of surgery, apparently no activation of the peripheral opioid receptors occurs. Thus, a peripheral effect of opioids could not be demonstrated in this model...
  10. doi request reprint [Comparison of the peripheral and central effects of opiates after iliac crest transplants. Reconstruction of severely atrophied maxilla]
    A S Virnik
    Abteilung für Mund, Kiefer und Gesichtschirurgie, Landeskrankenhaus Klagenfurt, Klagenfurt, Osterreich
    Schmerz 23:259-62, 264-6. 2009
    ..In this randomized double-blind study differences in the peripheral and central effects of opiates for pain treatment in the iliac crest region after augmentation of the severely resorbed maxilla were examined...
  11. ncbi request reprint Increased numbers of opioid expressing inflammatory cells do not affect intra-articular morphine analgesia
    R Likar
    Abteilung für Anaesthesiologie und Intensivmedizin, LKH Klagenfurt, St Veiter Strasse 47, A 9020 Klagenfurt, Austria
    Br J Anaesth 93:375-80. 2004
    ..Here we examined whether enhanced inflammation and END expression within the synovial tissue of patients undergoing arthroscopic knee surgery might shift the analgesic dose-response curve of intra-articular (i.a.) morphine...
  12. doi request reprint [Tonsillotomy and adenotonsillectomy in childhood. Study on postoperative pain therapy]
    M Platzer
    Abteilung für Anästhesiologie und Intensivmedizin, Klinikum Klagenfurt Wörthersee, Klagenfurt, Austria
    Anaesthesist 60:625-32. 2011
    ..The secondary goal was to assess the time until rescue analgesia was needed, propofol requirements and the incidence of vomiting and time of discharge from the postanaesthesia recovery unit (PARU)...
  13. ncbi request reprint [Preemptive randomized, double-blind study with lornoxicam in gynecological surgery]
    E Trampitsch
    Abteilung für Anästhesiologie und Intensivmedizin, LKH Klagenfurt, Austria
    Schmerz 17:4-10. 2003
    ..Lornoxicam is a non opioid analgesic belonging to the oxicam group. The aim of this study was to determine whether lornoxicam has a preemptive analgesic effect...
  14. ncbi request reprint [Postoperative transcutaneous electrical nerve stimulation (TENS) in shoulder surgery (randomized, double blind, placebo controlled pilot trial)]
    R Likar
    , LKH Klagenfurt, Austria
    Schmerz 15:158-63. 2001
    ..Furthermore there was a significant difference in the pain scores using the "Hamburg Pain Adjective List" in favour of the verum group. TENS applied postoperatively is a effective, simple modality with few side-effects...
  15. ncbi request reprint Efficacy of peripheral morphine analgesia in inflamed, non-inflamed and perineural tissue of dental surgery patients
    R Likar
    , LKH Klagenfurt, Klagenfurt, Austria
    J Pain Symptom Manage 21:330-7. 2001
    ..Thus, consistent with experimental studies, the requirement of an inflammatory process for the occurrence of peripheral opioid effects is also found in the clinical setting...
  16. doi request reprint Size of internal jugular vs subclavian vein in small infants: an observational, anatomical evaluation with ultrasound
    C Breschan
    Department of Anesthesia, LKH Klagenfurt, St Veiterstrasse 47, Klagenfurt, Austria
    Br J Anaesth 105:179-84. 2010
    ..A secondary goal was to determine the correlation of weight, height, head circumference, and age to the size and depth of these veins...
  17. ncbi request reprint [Spinal epidural abscess after long-term epidural catheterization]
    G Graf
    Abteilung für Anästhesiologie und Intensivmedizin, Landeskrankenhaus, Klagenfurt, Osterreich
    Schmerz 21:68-72. 2007
    ..Our contribution concludes with a detailed discussion and comparison of the literature...
  18. ncbi request reprint Analgesic efficacy and tolerability of transdermal buprenorphine in patients with inadequately controlled chronic pain related to cancer and other disorders: a multicenter, randomized, double-blind, placebo-controlled trial
    Reinhard Sittl
    University of Erlangen, Pain Clinic, Erlangen, Germany
    Clin Ther 25:150-68. 2003
    ..Buprenorphine is a potent opioid analgesic that is available in sublingual and parenteral formulations. A new formulation, buprenorphine transdermal delivery system (TDS), has been developed...
  19. ncbi request reprint [Cardiopulmonary resuscitation after heroin intoxication and hypothermia]
    M Platzer
    Abteilung für Anästhesiologie und Intensivmedizin, Landeskrankenhaus, St Veiterstrasse 47, 9020, Klagenfurt, Osterreich
    Anaesthesist 56:141-4. 2007
    ..This case report reviews the epidemiology, pathophysiology, prognostic markers and the therapeutic approaches of severe hypothermia...
  20. ncbi request reprint [Topical application of morphine gel in inflammatory mucosal and cutaneous lesions]
    M Platzer
    Abteilung für Anästhesiologie und Allgemeine Intensivmedizin, LKH Klagenfurt
    Schmerz 19:296-301. 2005
    ..The aim of this study was to demonstrate a peripheral local opioid effect using case examples involving inflammatory mucosal and cutaneous lesions...
  21. doi request reprint [Central venous catheter for newborns, infants and children]
    C Breschan
    Abt für Anästhesiologie, Landeskrankenhaus Klagenfurt, St Veiterstr 47, 9020, Klagenfurt, Osterreich
    Anaesthesist 58:897-900, 902-4. 2009
    ..In the case of haemodynamic instability, ultrasound should be used to exclude pericardial effusion...
  22. ncbi request reprint [Quality of life and pain in hospitalized geriatric patients]
    W Pipam
    Landeskrankenhaus Klagenfurt, St Veiter Strasse 4, Klagenfurt, Osterreich
    Schmerz 22:59-66. 2008
    ..To determine objective and subjective indications of quality of life in hospitalized geriatric patients...
  23. ncbi request reprint [Electrical point stimulation (P-STIM) via ear acupuncture: a randomized, double-blind, controlled pilot study in patients undergoing laparoscopic nephrctomyX]
    R Likar
    Abteilung für Anästhesiologie und Intensivmedizin, LKH Klagenfurt, Klagenfurt
    Schmerz 21:154-9. 2007
    ....
  24. doi request reprint [Analgesic efficacy of TENS therapy in patients with gonarthrosis. A prospective, randomised, placebo-controlled, double-blind study]
    B Gschiel
    Abteilung für Anästhesiologie und Intensivmedizin, Zentrum für Interdisziplinäre Schmerztherapie, Onkologie und Palliativmedizin, LKH Klagenfurt, St Veiter Str 47, 9020 Klagenfurt, Osterreich
    Schmerz 24:494-500. 2010
    ..The study included a 3-week stimulation period and 2-week observation period after the end of stimulation...
  25. ncbi request reprint Transdermal buprenorphine in clinical practice--a post-marketing surveillance study in 13,179 patients
    Norbert Griessinger
    Department of Anaesthesiology, Pain Clinic, University of Erlangen Nuernberg, Erlangen, Germany
    Curr Med Res Opin 21:1147-56. 2005
    ..The objective of this post-marketing surveillance study was to collect effectiveness and safety data on the labelled use of buprenorphine transdermal patches (Transtec*) under routine clinical conditions...
  26. doi request reprint [Problems of pain measurement and pain therapy in the elderly]
    Georg Pinter
    Haus der Geriatrie, Landeskrankenhaus Klagenfurt, Klagenfurt, Austria
    Wien Med Wochenschr 160:235-46. 2010
    ....
  27. ncbi request reprint [Anesthetic management of surgery in term and preterm infants]
    C Breschan
    Abteilung für Anästhesiologie, LKH, St Veiterstrasse 47, 9020, Klagenfurt, Osterreich
    Anaesthesist 55:1087-98. 2006
    ..Consideration will also be given to the anesthetic management of very low birth-weight infants with anesthetic key issues such as avoiding hyperoxia, keeping hemodynamic parameters as stable as possible and preventing hypothermia...
  28. ncbi request reprint [Propofol infusion syndrome]
    E Trampitsch
    Abt für Anästhesie und Allgemeine Intensivmedizin, Landeskrankenhaus, St Veiter Strasse 47, 9020 Klagenfurt, Austria
    Anaesthesist 55:1166-8. 2006
    ..The pathophysiology of this syndrome appears to involve a disturbance of mitochondrial metabolism induced by propofol. Our report involves a case of propofol infusion syndrome in a patient having undergone cardiac surgery...
  29. ncbi request reprint A prospective study comparing the analgesic efficacy of levobupivacaine, ropivacaine and bupivacaine in pediatric patients undergoing caudal blockade
    Christian Breschan
    Department of Anaesthesia, LKH Klagenfurt, Klagenfurt, Austria
    Paediatr Anaesth 15:301-6. 2005
    ....
  30. ncbi request reprint Midazolam does not reduce emergence delirium after sevoflurane anesthesia in children
    Christian Breschan
    Department of Anaesthesia, LKH Klagenfurt, Klagenfurt, Austria
    Paediatr Anaesth 17:347-52. 2007
    ..Furthermore the impact of these two doses of midazolam on sedation at induction of anesthesia was compared...
  31. ncbi request reprint Axillary brachial plexus block for treatment of severe forearm ischemia after arterial cannulation in an extremely low birth-weight infant
    Christian Breschan
    Department of Anaesthesia, LKH Klagenfurt, Klagenfurt, Austria
    Paediatr Anaesth 14:681-4. 2004
    ..Brachial plexus blockade and active vasodilatation in tiny neonates after severe local ischemia are discussed...
  32. ncbi request reprint Involvement of intra-articular corticotropin-releasing hormone in postoperative pain modulation
    Rudolf Likar
    Abteilung für Anaesthesiologie und Intensivmedizin, LKH Klagenfurt, St Veiter Strasse 47, A 9020 Klagenfurt, Austria
    Clin J Pain 23:136-42. 2007
    ....
  33. ncbi request reprint Opioid-induced mast cell activation and vascular responses is not mediated by mu-opioid receptors: an in vivo microdialysis study in human skin
    James A Blunk
    Department of Anesthesiology, University Hospital, Erlangen, Germany
    Anesth Analg 98:364-70, table of contents. 2004
    ..Because naloxone did not attenuate these effects, it is unlikely that mu-opioid receptors are involved in the activation of mast cells...
  34. ncbi request reprint [Cancer pain from the nurses' perspective--findings from Austria]
    Olivia Kada
    Fachhochschule Kärnten, Studienbereich Gesundheit und Pflege, Feldkirchen in Kärnten
    Pflege Z 60:626-30. 2007
    ....
  35. ncbi request reprint [Transdermal buprenorphine for treatment of chronic tumor and non-tumor pain]
    Rudolf Likar
    Landeskrankenhaus Klagenfurt, Abteilung für Anästhesiologie und Intensivmedizin, Schmerzambulanz, St Veiter Strasse 47, A 9020 Klagenfurt
    Wien Med Wochenschr 153:317-22. 2003
    ....
  36. ncbi request reprint High doses of topically applied lidocaine in a cancer patient
    Ilca Ricarda Wilhelm
    J Pain Symptom Manage 30:203-4. 2005
  37. ncbi request reprint Withdrawal following sufentanil/propofol and sufentanil/midazolam. Sedation in surgical ICU patients: correlation with central nervous parameters and endogenous opioids
    Maria Korak-Leiter
    Department of Anaesthesia and Intensive Care Medicine, County Hospital Klagenfurt, Austria
    Intensive Care Med 31:380-7. 2005
    ..To assess the nature of this phenomenon, patients in a surgical ICU following ventilatory support and sedation with an opioid/hypnotic/sedative were studied...
  38. ncbi request reprint The role of opioid analgesics in rheumatoid disease in the elderly population
    Norbert Griessinger
    Department of Anesthesiology, University Erlangen Nurnberg, Erlangen, Germany
    Drugs Aging 20:571-83. 2003
    ..This opens the way to new therapeutic options in the future through the development of systemic peripherally selective opioids without CNS adverse effects...
  39. ncbi request reprint Leukonychia following high altitude exposure
    Martin Burtscher
    High Alt Med Biol 3:93-4. 2002
  40. ncbi request reprint On the role of the kidneys in the pathogenesis of edema formation during permanent morphine application/an experimental study in rats
    Sabine Supanz
    Institute of Pathophysiology, Med University of Graz, Graz, Austria
    Arzneimittelforschung 54:259-64. 2004
    ..The histological examination of kidneys revealed no differences among the various groups. These data indicate a role of the kidney in the induction of peripheral edema during permanent morphine administration...
  41. ncbi request reprint [Improvement of pain therapy in Austria]
    Rudolf Likar
    Schmerz 21:277. 2007