Research Topics
| L KramerSummaryAffiliation: University of Vienna Country: Austria Publications
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Detail Information
Publications
Previous episodes of hypoglycemic coma are not associated with permanent cognitive brain dysfunction in IDDM patients on intensive insulin treatmentL Kramer
Department of Medicine, University of Vienna, Austria
Diabetes 47:1909-14. 1998..Cognitive brain function, however, is subclinically impaired in relation to duration of diabetes...
Mercury exposure in protein A immunoadsorptionLudwig Kramer
Department of Medicine IV, University of Vienna Medical School, Vienna, Austria
Nephrol Dial Transplant 19:451-6. 2004..1% solution) and rinsed with phosphate buffer before use. In this study, we tested the hypothesis of systemic mercury exposure in protein A immunoadsorption...
Successful treatment of refractory cerebral oedema in ecstasy/cocaine-induced fulminant hepatic failure using a new high-efficacy liver detoxification device (FPSA-Prometheus)Ludwig Kramer
Department of Medicine IV, University of Vienna Medical School, Vienna, Austria
Wien Klin Wochenschr 115:599-603. 2003..In conclusion, efficient extracorporeal detoxification may be an option for reversal of hyperammonaemia and refractory cerebral oedema in ecstasy/cocaine-induced acute liver failure...
Extracorporeal treatment in fulminant hepatic failure: pathophysiologic considerationsL Kramer
Department of Medicine IV, University of Vienna Medical School, Vienna, Austria
Int J Artif Organs 25:929-34. 2002..This article aims to integrate pathophysiology of hepatic encephalopathy and cerebral edema into a proposed future concept of liver support...
Influence of hydroxy ethyl starch infusion on serum bilirubin levels in cirrhotic patients treated with artificial liver supportL Kramer
Int J Artif Organs 25:918-22. 2002..The role of potentially confounding factors in liver support studies is discussed further...
Subclinical impairment of brain function in chronic hepatitis C infectionLudwig Kramer
Department of Medicine IV, University Hospital Vienna, Wahringer Gurtel 18 20, Vienna, Austria
J Hepatol 37:349-54. 2002..This study tested the hypothesis of a subclinical cognitive dysfunction in HCV-infected patients...
Hepatorenal syndromeLudwig Kramer
Department of Medicine IV, Division of Nephrology, University of Vienna Medical School, Austria
Semin Nephrol 22:290-301. 2002..The definite role of these promising developments, however, is still uncertain, emphasizing the need for large prospective multicentric investigations...
A controlled study of sorbent suspension dialysis in chronic liver disease and hepatic encephalopathyL Kramer
Department of Medicine IV, University of Vienna Medical School, Austria
Int J Artif Organs 24:434-42. 2001..In conclusion, a six-hour treatment with sorbent suspension dialysis did not ameliorate the clinical stage of HE but improved neurophysiologic function in cirrhotic patients who had not responded to conventional medical treatment...
Partial pressure of ammonia versus ammonia in hepatic encephalopathyL Kramer
University Hospital Vienna, Department of Medicine IV, Vienna, Austria
Hepatology 31:30-4. 2000..These findings support the ammonia hypothesis of HE and suggest that pNH(3) might be superior to total ammonia in the pathophysiological evaluation of HE...
Biocompatibility of a cuprophane charcoal-based detoxification device in cirrhotic patients with hepatic encephalopathyL Kramer
Department of Medicine IV, Intensive Care Unit, University of Vienna, Austria
Am J Kidney Dis 36:1193-200. 2000..We suggest further developments in design and appropriate strategies of anticoagulation to improve the biocompatibility of artificial liver support...
Improved outcome prediction in unconscious cardiac arrest survivors with sensory evoked potentials compared with clinical assessmentC Madl
Department of Internal Medicine IV, University of Vienna, Austria
Crit Care Med 28:721-6. 2000..To compare the prognostic ability of sensory evoked potentials in cardiac arrest survivors with the outcome predicted by a panel of experienced emergency physicians based on detailed prehospital, clinical, and laboratory data...
Heavy chronic alcohol abuse has no additional adverse effect on the function of extrahepatic organs and ICU mortality in patients with liver cirrhosisC Zauner
Department of Internal Medicine IV, Universitatskliniken, Allgemeines Krankenhaus der Stadt Wien, Vienna, Austria
Wien Klin Wochenschr 111:810-4. 1999..We questioned whether heavy chronic alcohol abuse influences extrahepatic organ failure and ICU mortality in cirrhotic patients admitted to a medical intensive care unit...
Time-dependency of sensory evoked potentials in comatose cardiac arrest survivorsA Gendo
Department of Internal Medicine IV, Intensive Care Unit 13 H1, University of Vienna, Wahringer Gurtel 18 20, 1090 Vienna, Austria
Intensive Care Med 27:1305-11. 2001..To assess the validity of early sensory evoked potential (SEP) recording for reliable outcome prediction in comatose cardiac arrest survivors within 48 h after restoration of spontaneous circulation (ROSC)...
Neurophysiological evidence of cognitive impairment in patients without hepatic encephalopathy after transjugular intrahepatic portosystemic shuntsLudwig Kramer
Department of Medicine IV, University of Vienna Medical School, Vienna General Hospital, Austria
Am J Gastroenterol 97:162-6. 2002..A further subclinical deterioration of cognitive processing was observed 6 months after the TIPS. These findings demonstrate an aggravation of subclinical hepatic encephalopathy after a TIPS...
Metabolic encephalopathy in critically ill patients suffering from septic or nonseptic multiple organ failureC Zauner
Department of Internal Medicine IV, University of Vienna, Austria
Crit Care Med 28:1310-5. 2000....
Effects of sorbent suspension dialysis on plasma amino acid levels in cirrhotic patients with refractory hepatic encephalopathyE Bauer
Department of Medicine IV, University of Vienna Medical School, Vienna, Austria
Int J Artif Organs 25:923-8. 2002..In conclusion, a 6-hour treatment with sorbent dialysis did not significantly influence plasma levels of amino acids and did not ameliorate the clinical grade of hepatic encephalopathy...
Short-term prognosis in critically ill patients with liver cirrhosis: an evaluation of a new scoring systemC Zauner
Department of Internal Medicine IV, University of Vienna, Austria
Eur J Gastroenterol Hepatol 12:517-22. 2000..This study was performed to assess the physiological and laboratory parameters which are able to identify on ICU admission the cirrhotic patients who are most likely to die...
Electrophysiological assessment of the afferent sensory pathway in cardiac arrest survivorsE Bauer
Department of Medicine IV, University of Vienna Medical School, Austria
Eur J Clin Invest 33:283-7. 2003..We hypothesized that hypoxic-ischaemic brain damage increases along the afferent sensory pathway with a stepwise decrease of detectable somatosensory evoked potential peaks...
Liver penetration by a duodenal ulcer in a young womanG Novacek
Department of Internal Medicine IV, Division of Gastroenterology and Hepatology, University of Waeringer Guertel 18 20, A 1090 Vienna, Austria
J Clin Gastroenterol 33:56-60. 2001..We also review 11 other reported cases of endoscopically and histologically diagnosed peptic ulcer penetration into the liver...
Ascites and intraabdominal infectionLudwig Kramer
Department of Medicine IV, Vienna University Medical School, A 1090 Vienna, Austria
Curr Opin Crit Care 10:146-51. 2004..This review will give an overview of current trends in diagnosis, treatment, and pathogenesis of ascites and intraabdominal infection in cirrhotic and noncirrhotic critically ill patients...
Neurocognitive deficit following mitral valve surgeryMichael Grimm
Department of Cardio Thoracic Surgery, Vienna General Hospital, University of Vienna, Waehringer Guertel 18 20, A 1090 Vienna, Austria
Eur J Cardiothorac Surg 23:265-71. 2003..The aim of this prospective, contemporary study was to objectively measure neurocognitive brain function following mechanical mitral valve replacement and mitral valve repair...
Impaired subcortical and cortical sensory evoked potential pathways in septic patientsChristian Zauner
Department of Internal Medicine IV, Intensive Care Unit, University of Vienna, Vienna, Austria
Crit Care Med 30:1136-9. 2002....
Relative impact of fatigue and subclinical cognitive brain dysfunction on health-related quality of life in chronic hepatitis C infectionLudwig Kramer
Department of Medicine IV, Medical University Vienna, Austria
AIDS 19:S85-92. 2005..To assess the relative impact of fatigue and subclinical cognitive brain dysfunction on the impairment of health-related quality of life (HRQL) in hepatitis C virus (HCV) infection...
Acute liver failureLudwig Kramer
Department of Medicine IV, University of Vienna, Vienna, Austria
Wien Klin Wochenschr 116:67-81. 2004..Anti-apoptotic interventions are among the most promising pharmacological options for the near future...
Neurocognitive deficit following coronary artery bypass grafting: a prospective study of surgical patients and nonsurgical controlsDaniel Zimpfer
Department of Cardiothoracic Surgery, University of Vienna, Vienna, Austria
Ann Thorac Surg 78:513-8; discussion 518-9. 2004..CONCLUSIONS: As shown by means of objective measures, and in comparison to nonsurgical controls, coronary artery bypass grafting with cardiopulmonary bypass grafting causes long-term neurocognitive deficit...
Normothermic cardiopulmonary bypass is beneficial for cognitive brain function after coronary artery bypass grafting--a prospective randomized trialM Grimm
Department of Cardiothoracic Surgery, University of Vienna, Währinger Gürtel 18 20 A 1090, Vienna, Austria
Eur J Cardiothorac Surg 18:270-5. 2000..Hypothermic and normothermic cardiopulmonary bypass (CPB) have resulted in apparently contradictionary cardiac and neurologic outcome. Cerebrovascular risk and cognitive dysfunction associated with normothermic CPB still remain uncertain...
Graft versus host disease after orthotopic liver transplantation documented by analysis of short tandem repeat polymorphismsM Schoniger-Hekele
Universitatsklinik fur Innere Medizin IV, Klinische Abteilung Gastroenterologie und Hepatologie, Medical University of Vienna, Vienna, Austria
Digestion 74:169-73. 2006....
Severity of organ failure is an independent predictor of intracranial hypertension in acute liver failureReinhard Kitzberger
Department of Gastroenterology, Hepatology and Medical Intensive Care Medicine, Medical University Hospital Vienna, Vienna, Austria
Clin Gastroenterol Hepatol 7:1000-6. 2009..We investigated whether the severity of organ failure was associated with intracranial hypertension and evaluated the correlation between NH(3) and pNH(3) and grade of hepatic encephalopathy...
Molecular and clinical characterisation of homocystinuria in two Austrian families with cystathionine beta-synthase deficiencyU Tröndle
Department of Laboratory Medicine, Division of Endocrinology and Metabolism, University of Vienna, Wahringer Gurtel 18 20, A 1090 Vienna
Acta Med Austriaca 28:145-51. 2001..Both genotypes do not allow for normalisation of total homocysteine plasma levels following vitamin therapy...
Cognitive deficit after aortic valve replacementDaniel Zimpfer
Department of Cardio-Thoracic Surgery, Vienna General Hospital, University of Vienna, Austria
Ann Thorac Surg 74:407-12; discussion 412. 2002..Further studies are needed to clarify the potential pathologic mechanisms causing an ongoing cognitive impairment in patients with biological aortic valve prostheses...
Incidence and prognosis of early hepatic dysfunction in critically ill patients--a prospective multicenter studyLudwig Kramer
Department of Medicine IV, Core Unit for Medical Statistics and Informatics, Medical University of Vienna, Vienna General Hospital, A 1090 Vienna, Austria
Crit Care Med 35:1099-104. 2007..We investigated the incidence and prognostic implications of early hepatic dysfunction (serum bilirubin >2 mg/dL within 48 hrs of admission)...
Citrate pharmacokinetics and metabolism in cirrhotic and noncirrhotic critically ill patientsLudwig Kramer
Department of Medicine IV, University of Vienna Medical School, Austria
Crit Care Med 31:2450-5. 2003..Metabolic consequences of citrate infusion were not different between groups in this study but may be more pronounced in prolonged infusion...
Effects of TIPS on liver perfusion measured by dynamic CTClaudia Weidekamm
Department of Radiology, Medical University of Vienna, Waehringer Guertel 18-20, Vienna A-1090, Austria
AJR Am J Roentgenol 184:505-10. 2005..TIPS placement caused a statistically significant increase of the hepatic arterial and total hepatic perfusion. The portal venous parenchymal perfusion remained unchanged...
MARS and the failing liver-Any help from the outer space?Peter Ferenci
Hepatology 46:1682-4. 2007
