Stefan Kiechl

Summary

Affiliation: University of Innsbruck
Country: Austria

Publications

  1. ncbi request reprint Poor response to activated protein C as a prominent risk predictor of advanced atherosclerosis and arterial disease
    S Kiechl
    Department of Neurology, Innsbruck University Clinic, Innsbruck, Austria
    Circulation 99:614-9. 1999
  2. pmc Two families with autosomal dominant progressive external ophthalmoplegia
    S Kiechl
    Department of Neurology, University Hospital Innsbruck, Austria
    J Neurol Neurosurg Psychiatry 75:1125-8. 2004
  3. ncbi request reprint [Prevention of stroke]
    Stefan Kiechl
    Universitätsklinik für Neurologie, Anichstrasse 35, A 6020 Innsbruck, Osterreich
    Wien Med Wochenschr 153:6-13. 2003
  4. ncbi request reprint Active and passive smoking, chronic infections, and the risk of carotid atherosclerosis: prospective results from the Bruneck Study
    Stefan Kiechl
    Department of Neurology, Innsbruck University Hospital, Innsbruck, Austria
    Stroke 33:2170-6. 2002
  5. ncbi request reprint Toll-like receptor 4 polymorphisms and atherogenesis
    Stefan Kiechl
    Department of Neurology, University Clinic, Innsbruck, Austria
    N Engl J Med 347:185-92. 2002
  6. ncbi request reprint Toll-like receptor 4 and atherogenesis
    Stefan Kiechl
    Department of Neurology, Innsbruck University Clinic, Innsbruck, Austria
    Ann Med 35:164-71. 2003
  7. ncbi request reprint Osteoprotegerin is a risk factor for progressive atherosclerosis and cardiovascular disease
    Stefan Kiechl
    Department of Neurology, University Clinic, Anichstrasse 35, A 6020 Innsbruck, Austria
    Circulation 109:2175-80. 2004
  8. pmc Different clinical aspects of debrancher deficiency myopathy
    S Kiechl
    Department of Neurology, Innsbruck University Clinic, Innsbruck, Austria
    J Neurol Neurosurg Psychiatry 67:364-8. 1999
  9. ncbi request reprint Reversible severe myopathy of respiratory muscles due to adult-onset type III glycogenosis
    S Kiechl
    Department of Neurology, Innsbruck University Clinic, Austria
    Neuromuscul Disord 9:408-10. 1999
  10. doi request reprint Cellular aging reflected by leukocyte telomere length predicts advanced atherosclerosis and cardiovascular disease risk
    Peter Willeit
    Department of Neurology, Innsbruck Medical University, Innsbruck, Austria
    Arterioscler Thromb Vasc Biol 30:1649-56. 2010

Detail Information

Publications82

  1. ncbi request reprint Poor response to activated protein C as a prominent risk predictor of advanced atherosclerosis and arterial disease
    S Kiechl
    Department of Neurology, Innsbruck University Clinic, Innsbruck, Austria
    Circulation 99:614-9. 1999
    ..The potential role of activated protein C (APC) resistance in arterial thrombosis and disease is a matter of ongoing controversy...
  2. pmc Two families with autosomal dominant progressive external ophthalmoplegia
    S Kiechl
    Department of Neurology, University Hospital Innsbruck, Austria
    J Neurol Neurosurg Psychiatry 75:1125-8. 2004
    ..We report here the clinical and genetic features of two new families with autosomal dominant progressive external ophthalmoplegia (adPEO)...
  3. ncbi request reprint [Prevention of stroke]
    Stefan Kiechl
    Universitätsklinik für Neurologie, Anichstrasse 35, A 6020 Innsbruck, Osterreich
    Wien Med Wochenschr 153:6-13. 2003
    ..In addition, there will be a dispute on challenges regarding carotid surgery and optimal drug therapy as well as on dietary guidelines...
  4. ncbi request reprint Active and passive smoking, chronic infections, and the risk of carotid atherosclerosis: prospective results from the Bruneck Study
    Stefan Kiechl
    Department of Neurology, Innsbruck University Hospital, Innsbruck, Austria
    Stroke 33:2170-6. 2002
    ..The present study sought to estimate the contribution of chronic infections to the variability of atherosclerosis severity among smokers...
  5. ncbi request reprint Toll-like receptor 4 polymorphisms and atherogenesis
    Stefan Kiechl
    Department of Neurology, University Clinic, Innsbruck, Austria
    N Engl J Med 347:185-92. 2002
    ..We determined whether recently discovered genetic variants of toll-like receptor 4 (TLR4) that confer differences in the inflammatory response elicited by bacterial lipopolysaccharide are related to the development of atherosclerosis...
  6. ncbi request reprint Toll-like receptor 4 and atherogenesis
    Stefan Kiechl
    Department of Neurology, Innsbruck University Clinic, Innsbruck, Austria
    Ann Med 35:164-71. 2003
    ..The aim of this review is to critically discuss current experimental and epidemiological evidence for a role of TLR4 in atherogenesis and to highlight the main controversies and perspectives in this emerging field of vascular biology...
  7. ncbi request reprint Osteoprotegerin is a risk factor for progressive atherosclerosis and cardiovascular disease
    Stefan Kiechl
    Department of Neurology, University Clinic, Anichstrasse 35, A 6020 Innsbruck, Austria
    Circulation 109:2175-80. 2004
    ..Recent experimental research has implicated osteoprotegerin in atherogenesis, but epidemiological confirmation of this concept is sparse...
  8. pmc Different clinical aspects of debrancher deficiency myopathy
    S Kiechl
    Department of Neurology, Innsbruck University Clinic, Innsbruck, Austria
    J Neurol Neurosurg Psychiatry 67:364-8. 1999
    ..To characterise the main clinical phenotypes of debrancher deficiency myopathy and to increase awareness for this probably underdiagnosed disorder...
  9. ncbi request reprint Reversible severe myopathy of respiratory muscles due to adult-onset type III glycogenosis
    S Kiechl
    Department of Neurology, Innsbruck University Clinic, Austria
    Neuromuscul Disord 9:408-10. 1999
    ..To our knowledge this is the first reported case of adult-onset debrancher deficiency myopathy presenting with subacute respiratory failure and responding to high-protein diet...
  10. doi request reprint Cellular aging reflected by leukocyte telomere length predicts advanced atherosclerosis and cardiovascular disease risk
    Peter Willeit
    Department of Neurology, Innsbruck Medical University, Innsbruck, Austria
    Arterioscler Thromb Vasc Biol 30:1649-56. 2010
    ..To determine the association between leukocyte telomere length (TL) and atherosclerosis and its clinical sequelae stroke and myocardial infarction...
  11. pmc Sex and age interaction with genetic association of atherogenic uric acid concentrations
    Anita Brandstätter
    Division of Genetic Epidemiology, Department of Medical Genetics, Molecular and Clinical Pharmacology, Innsbruck Medical University, Schöpfstr 41, A 6020 Innsbruck, Austria
    Atherosclerosis 210:474-8. 2010
    ..High serum uric acid levels are associated with gout, atherosclerosis and cardiovascular disease. Three genes (SLC2A9, ABCG2, and SLC17A3) were reported to be involved in the regulation of uric acid levels...
  12. doi request reprint Fibrinogen degradation coagulopathy and bleeding complications after stroke thrombolysis
    Benjamin Matosevic
    Department of Neurology, Innsbruck Medical University, Innsbruck, Austria
    Neurology 80:1216-24. 2013
    ....
  13. doi request reprint [Implementation of thrombolysis in acute stroke--10-year results of the Innsbruck stroke registry]
    Benjamin Matosevic
    Universitätsklinik für Neurologie, Medizinische Universitat Innsbruck, Austria
    Wien Klin Wochenschr 121:750-6. 2009
    ..A large patient registry has recently confirmed the safe implementation of this therapy in the clinical routine setting...
  14. ncbi request reprint Oxidized phospholipids, lipoprotein(a), lipoprotein-associated phospholipase A2 activity, and 10-year cardiovascular outcomes: prospective results from the Bruneck study
    Stefan Kiechl
    Department of Neurology, Medical University of Innsbruck, Austria
    Arterioscler Thromb Vasc Biol 27:1788-95. 2007
    ..Oxidized phospholipids (OxPL) circulate on apolipoprotein B-100 particles (OxPL/apoB), and primarily on Lp(a) lipoprotein (a) [Lp(a)]. The relationship of OxPL/apoB levels to future cardiovascular events is not known...
  15. ncbi request reprint Increased risk of atherosclerosis is confined to CagA-positive Helicobacter pylori strains: prospective results from the Bruneck study
    Manuel Mayr
    Institute for Biomedical Aging Research, Austrian Academy of Sciences, Innsbruck, Austria
    Stroke 34:610-5. 2003
    ..Accumulating evidence indicates that a variety of infections contribute to the pathogenesis of atherosclerosis, but there is controversy concerning the impact of Helicobacter pylori infections in atherosclerosis...
  16. doi request reprint Telomere length and risk of incident cancer and cancer mortality
    Peter Willeit
    Department of Neurology, Innsbruck Medical University, Anichstrasse 35, 6020 Innsbruck, Austria
    JAMA 304:69-75. 2010
    ..Telomeres are essential to preserve the integrity of the genome. Critically short telomeres lead to replicative cell senescence and chromosomal instability and may thereby increase cancer risk...
  17. doi request reprint Coronary artery disease-related genetic variant on chromosome 10q11 is associated with carotid intima-media thickness and atherosclerosis
    Stefan Kiechl
    Department of Neurology, Medical University Innsbruck, Innsbruck, Austria
    Arterioscler Thromb Vasc Biol 30:2678-83. 2010
    ..To investigate whether chromosome 10q11.21 influences common carotid intima-media thickness (IMT) and atherosclerosis and whether it is associated with stromal cell-derived factor-1α (SDF-1α) plasma levels...
  18. ncbi request reprint Soluble receptor activator of nuclear factor-kappa B ligand and risk for cardiovascular disease
    Stefan Kiechl
    Department of Neurology, Innsbruck Medical University, Anichstr 35, A 6020 Innsbruck, Austria
    Circulation 116:385-91. 2007
    ....
  19. pmc Recanalization of extracranial internal carotid artery occlusion after i.v. thrombolysis for acute ischemic stroke
    Raimund Pechlaner
    Department of Neurology, Innsbruck Medical University, Innsbruck, Tyrol, Austria
    PLoS ONE 8:e55318. 2013
    ....
  20. ncbi request reprint Allergic rhinitis, asthma, and atherosclerosis in the Bruneck and ARMY studies
    Michael Knoflach
    Department of Pathophysiology, Innsbruck Medical University, Innsbruck, Austria
    Arch Intern Med 165:2521-6. 2005
    ..Several diseases characterized by chronic inflammation and immune activation have been linked to enhanced risk for atherosclerosis. The potential association between allergies and atherosclerosis, however, remains to be defined...
  21. doi request reprint Asymmetric and symmetric dimethylarginines are of similar predictive value for cardiovascular risk in the general population
    Stefan Kiechl
    Department of Neurology, Medical University Innsbruck, Innsbruck, Austria
    Atherosclerosis 205:261-5. 2009
    ..While increased plasma levels of ADMA have been reported in different cardiovascular disease states, its association with symmetric dimethylarginine (SDMA) has not been evaluated in a prospective population-based study...
  22. pmc A common variant in the adiponutrin gene influences liver enzyme values
    Barbara Kollerits
    Division of Genetic Epidemiology, Department of Medical Genetics, Molecular and Clinical Pharmacology, Innsbruck Medical University, , A 6020 Innsbruck, Austria
    J Med Genet 47:116-9. 2010
    ..Conclusion The highly significant associations of this transversion polymorphism within the adiponutrin gene with increased ALT and AST concentrations support a role for adiponutrin as a susceptibility gene for hepatic dysfunction...
  23. ncbi request reprint Marburg I polymorphism of factor VII--activating protease: a prominent risk predictor of carotid stenosis
    Johann Willeit
    Department of Neurology, University Clinics, Innsbruck, Austria
    Circulation 107:667-70. 2003
    ..The Marburg I polymorphism of FSAP impairs this potential and may thus facilitate arterial thrombosis...
  24. doi request reprint Prognostic relevance of limb shaking in symptomatic carotid artery occlusion
    Michael Knoflach
    Department of Neurology, Medical University of Innsbruck, Innsbruck, Austria
    Cerebrovasc Dis 32:35-40. 2011
    ..Reliable data on the frequency of these phenomena and their potential prognostic relevance are still sparse...
  25. pmc Pentraxin-3 as a marker of advanced atherosclerosis results from the Bruneck, ARMY and ARFY Studies
    Michael Knoflach
    Department of Neurology, Medical University, Innsbruck, Austria
    PLoS ONE 7:e31474. 2012
    ..Pentraxins like C-reactive protein are key components of the innate immune system. Recently, pentraxin-3 (PTX3) has been proposed to be a specific marker of vascular inflammation, yet its association with atherosclerosis is still unclear...
  26. doi request reprint Influences on the reduction of relative telomere length over 10 years in the population-based Bruneck Study: introduction of a well-controlled high-throughput assay
    Silvia Ehrlenbach
    Division of Genetic Epidemiology, Department of Medical Genetics, Molecular and Clinical Pharmacology, Innsbruck Medical University, Innsbruck, Austria
    Int J Epidemiol 38:1725-34. 2009
    ..Short telomeres are linked to age-associated diseases and cancer. Our aim was to determine the decrease rate of relative telomere length (RTL) over 10 years and whether this rate was influenced by age, sex and smoking behaviour...
  27. doi request reprint Stroke thrombolysis: having more time translates into delayed therapy: data from the Austrian Stroke Unit Registry
    Julia Ferrari
    Department of Neurology, Hospital Barmherzige Brueder, Vienna, Austria
    Stroke 41:2001-4. 2010
    ..Previous small-scale studies suggested that the earlier patients arrive, the longer it takes to administer recombinant tissue plasminogen activator...
  28. doi request reprint Subtherapeutic warfarin therapy entails an increased bleeding risk after stroke thrombolysis
    Michael Ruecker
    Department of Neurology, Medical University Innsbruck, Innsbruck, Austria
    Neurology 79:31-8. 2012
    ..To quantify the risk for bleeding complications after thrombolysis for ischemic stroke in patients on warfarin (international normalized ratio [INR] ≤ 1.7) and to put these data into perspective with previous studies...
  29. doi request reprint Cardiovascular risk factors and atherosclerosis in young women: atherosclerosis risk factors in female youngsters (ARFY study)
    Michael Knoflach
    Department of Clinical Neurology, Innsbruck Medical University, Innsbruck, Austria
    Stroke 40:1063-9. 2009
    ..Little research has been conducted into risk factors of atherosclerosis development in young women...
  30. ncbi request reprint The osteoprotegerin/RANK/RANKL system: a bone key to vascular disease
    Stefan Kiechl
    Medical University Innsbruck, Department of Neurology, Anichstr 35, A 6020 Innsbruck, Austria
    Expert Rev Cardiovasc Ther 4:801-11. 2006
    ..RANKL in turn may be a suitable target for novel therapies. Pharmacological strategies for specific interference with the OPG/RANK/RANKL axis are currently being developed and evaluated in osteoporosis therapy...
  31. ncbi request reprint Cardiovascular risk factors and atherosclerosis in young males: ARMY study (Atherosclerosis Risk-Factors in Male Youngsters)
    Michael Knoflach
    Institute for Biomedical Ageing Research, Austrian Academy of Sciences, Innsbruck, Austria
    Circulation 108:1064-9. 2003
    ..Furthermore, new risk concepts of atherosclerosis focusing on inflammation, infections, and immunity have not yet been evaluated in this age group...
  32. ncbi request reprint Urinary albumin excretion is independently associated with carotid and femoral artery atherosclerosis in the general population
    Martin Furtner
    Department of Neurology, Innsbruck Medical University Clinic, Anichstrasse 35, A 6020 Innsbruck, Austria
    Eur Heart J 26:279-87. 2005
    ..Whether or not this notion applies to the general population is a matter of ongoing controversy because none of the few previous investigations among non-diabetics strictly represent the general community...
  33. doi request reprint [Juvenile stroke--results from the Austrian Stroke Registry]
    Michael Knoflach
    Universitätsklinik für Neurologie, Medizinische Universitat Innsbruck, Innsbruck, Austria
    Wien Med Wochenschr 158:453-7. 2008
    ..Young men experience a significant delay in the onset-to-door time in comparison to other segments of the population. Increasing awareness about the relevance of stroke in the young is a valuable target for future health campaigns...
  34. doi request reprint Progressive leukoencephalopathy caused by primary CNS lymphoma
    Benjamin Matosevic
    Department of Neurology, Medical University Innsbruck, Innsbruck 6020, Austria
    J Clin Pathol 63:359-61. 2010
    ..This report intends to increase awareness among neurologists and other stroke physicians about this disease in order to accelerate diagnosis and initiation of treatment...
  35. ncbi request reprint Prevalence of movement disorders in men and women aged 50-89 years (Bruneck Study cohort): a population-based study
    Gregor K Wenning
    Department of Neurology, Medical University Innsbruck, Innsbruck, Austria
    Lancet Neurol 4:815-20. 2005
    ..We sought to assess the prevalence of all common categories of movement disorders in a population, accounting for sex differences and age trends...
  36. ncbi request reprint Kaleidoscopic vision and a jerking leg on the ski slope
    Stefan Kiechl
    Department of Neurology, Medical University Innsbruck, Austria
    Lancet 370:1878. 2007
  37. pmc Prevalence and burden of gait disorders in elderly men and women aged 60-97 years: a population-based study
    Philipp Mahlknecht
    Department of Neurology, Innsbruck Medical University, Innsbruck, Austria
    PLoS ONE 8:e69627. 2013
    ..Although gait disorders are common in the elderly, the prevalence and overall burden of these disorders in the general community is not well defined...
  38. doi request reprint Blockade of receptor activator of nuclear factor-κB (RANKL) signaling improves hepatic insulin resistance and prevents development of diabetes mellitus
    Stefan Kiechl
    Department of Neurology, Medical University Innsbruck, Innsbruck, Austria
    Nat Med 19:358-63. 2013
    ..Overall, this study provides evidence for a role of RANKL signaling in the pathogenesis of T2DM. If so, translation to the clinic may be feasible given current pharmacological strategies to lower RANKL activity to treat osteoporosis...
  39. pmc Association of variation at the ABO locus with circulating levels of soluble intercellular adhesion molecule-1, soluble P-selectin, and soluble E-selectin: a meta-analysis
    Stefan Kiechl
    Innsbruck Medical University, Innsbruck, Austria
    Circ Cardiovasc Genet 4:681-6. 2011
    ..To evaluate these associations and the effect sizes, we performed a meta-analysis with new and previous reported data for polymorphism rs579459...
  40. ncbi request reprint Non-toxic cadmium concentrations induce vascular inflammation and promote atherosclerosis
    Michael Knoflach
    Department of Neurology, Innsbruck Medical University, Innsbruck, Austria
    Circ J 75:2491-5. 2011
    ..Cadmium is a potential new risk factor for early atherosclerosis and cardiovascular diseases in humans, yet pathogenetic mechanisms are still a matter of debate...
  41. pmc Genetic evidence for a role of adiponutrin in the metabolism of apolipoprotein B-containing lipoproteins
    Barbara Kollerits
    Division of Genetic Epidemiology, Department of Medical Genetics, Molecular and Clinical Pharmacology, Innsbruck Medical University, Innsbruck, Austria
    Hum Mol Genet 18:4669-76. 2009
    ..We did not observe clear evidence for associations with HDL cholesterol or triglyceride concentrations. In conclusion, our study suggests that adiponutrin is involved in the metabolism of apoB-containing lipoproteins...
  42. ncbi request reprint Neonatal characteristics and risk of atopic asthma in schoolchildren: results from a large prospective birth-cohort study
    Ursula Kiechl-Kohlendorfer
    Department of Paediatrics, Division of Neonatology, Neuropaediatrics and Metabolic Diseases, Innsbruck Medical University, Innsbruck, Austria
    Acta Paediatr 96:1606-10. 2007
    ..Identification of risk predictors for a hospitalization for atopic asthma in childhood may help design prevention programmes and improve our understanding of disease pathobiology...
  43. ncbi request reprint The role of immune activation in endotoxin-induced atherogenesis
    C J Wiedermann
    Department of Internal Medicine, Faculty of Medicine, University of Innsbruck, Innsbruck, Austria
    J Endotoxin Res 7:322-6. 2001
    ..The study provides epidemiological evidence that the atherogenic potential of endotoxemia is affected by concomitant immune activation...
  44. ncbi request reprint Plasma-induced endothelial activation associated with incident atherosclerosis: prospective results from the Bruneck Study
    P Schratzberger
    Department of Internal Medicine, Faculty of Medicine, University of Innsbruck, Austria
    J Cardiovasc Risk 7:285-91. 2000
    ..Whether systemic inflammation is an epiphenomenon of atherosclerosis or whether it is part of the atherosclerosis causal pathway requires further study...
  45. ncbi request reprint T-cell reactivity against HSP60 relates to early but not advanced atherosclerosis
    M Knoflach
    Department of Clinical Neurology, Innsbruck Medical University, Anichstr 35, A 6020 Innsbruck, Austria
    Atherosclerosis 195:333-8. 2007
    ..The potential role of cellular immune reactions against HSP60 has so far attracted little attention in epidemiological research...
  46. ncbi request reprint Biology of arterial atheroma
    J Willeit
    Department of Neurology, Innsbruck University Clinic, Innsbruck, Austria
    Cerebrovasc Dis 10:1-8. 2000
    ....
  47. ncbi request reprint Vascular endothelial growth factor in CSF: a biological marker for carcinomatous meningitis
    G Stockhammer
    Departments of Neurology, University of Innsbruck, Innsbruck, Austria
    Neurology 54:1670-6. 2000
    ..To determine the value of vascular endothelial growth factor (VEGF) in CSF as a marker for carcinomatous meningitis (CM)...
  48. ncbi request reprint Juvenile asymmetric segmental spinal muscular atrophy (Hirayama's disease): three cases without evidence of "flexion myelopathy"
    J Willeit
    Departments of Neurology, Paediatrics, and Magnetic Resonance and Spectroscopy, University of Innsbruck, Austria
    Acta Neurol Scand 104:320-2. 2001
    ..In all these patients pathomechanism distinct from mechanical damage must be assumed...
  49. ncbi request reprint Distal myasthenia gravis frequency and clinical course in a large prospective series
    P Werner
    Department of Neurology, Innsbruck University, Innsbruck, Austria
    Acta Neurol Scand 108:209-11. 2003
    ..The aim of the current study was to assess the frequency of primarily distal MG in the Tyrol and to describe its clinical peculiarities...
  50. ncbi request reprint Role of lipoprotein(a) and apolipoprotein(a) phenotype in atherogenesis: prospective results from the Bruneck study
    F Kronenberg
    Institute of Medical Biology and Human Genetics, University of Innsbruck, Austria
    Circulation 100:1154-60. 1999
    ..Epidemiological studies may contribute to assessment of the relevance of these findings in the general population...
  51. ncbi request reprint Distinct risk profiles of early and advanced atherosclerosis: prospective results from the Bruneck Study
    J Willeit
    Department of Neurology, Innsbruck University Clinic, Austria
    Arterioscler Thromb Vasc Biol 20:529-37. 2000
    ..The multifactorial etiology of atherosclerosis, which goes far beyond the traditional risk factors, has not yet achieved adequate attention in clinical practice and disease prevention...
  52. ncbi request reprint Association of endotoxemia with carotid atherosclerosis and cardiovascular disease: prospective results from the Bruneck Study
    C J Wiedermann
    Department of Internal Medicine, Medical Faculty, University of Innsbruck, Austria
    J Am Coll Cardiol 34:1975-81. 1999
    ..Focus of the current study was on the significance of bacterial endotoxin, which shows a variety of pro-atherogenic properties and may occur at high concentration in the circulation of infected subjects...
  53. pmc Epidemiology of apparent life threatening events
    U Kiechl-Kohlendorfer
    Department of Paediatrics, Division of Neonatology, University of Innsbruck Medical School, Innsbruck, Austria
    Arch Dis Child 90:297-300. 2005
    ..To investigate the epidemiology and risk factors of apparent life threatening events (ALTE)...
  54. pmc Sex-specific association of the putative fructose transporter SLC2A9 variants with uric acid levels is modified by BMI
    Anita Brandstätter
    Department of Medical Genetics, Molecular and ClinicalPharmacology, Division of Genetic Epidemiology, Innsbruck Medical University, Innsbruck, Austria
    Diabetes Care 31:1662-7. 2008
    ..The aim of the present study was to examine the association of four single nucleotide polymorphisms within this gene with uric acid levels and to determine whether this association is modified by obesity...
  55. ncbi request reprint [SIDS prevention program in Tyrol]
    W Sperl
    Universitätsklinik für Kinder und Jugendheilkunde, Innsbruck, Osterreich
    Wien Klin Wochenschr 112:209-15. 2000
    ..9% vs. 14.5%, p < 0.01). Breast feeding became more popular. In all, the low-cost intervention programme in the Tyrol proved to be highly efficient in reducing the risk of SIDS and in maintaining this effect for several years...
  56. doi request reprint Early clinical worsening in patients with TIA or minor stroke: the Austrian Stroke Unit Registry
    J Ferrari
    Department of Neurology, Hospital Barmherzige Brueder, Vienna, Austria
    Neurology 74:136-41. 2010
    ..Our study sought to assess the rate of and predictors for early deterioration after TIA or minor stroke in a large nationwide survey among Austrian stroke units...
  57. doi request reprint Burden of atherosclerosis and risk of venous thromboembolism in patients with migraine
    J Schwaiger
    Department of Neurology, Innsbruck Medical University, Austria
    Neurology 71:937-43. 2008
    ..The aims of the present study were to investigate the potential association between migraine and atherosclerosis and to assess the risk of venous thromboembolism as a clinical surrogate for a procoagulant state in patients with migraine...
  58. doi request reprint Circulating microRNAs as novel biomarkers for platelet activation
    Peter Willeit
    Department of Neurology, Medical University Innsbruck, Austria
    Circ Res 112:595-600. 2013
    ..MicroRNA (miRNA) biomarkers are attracting considerable interest. Effects of medication, however, have not been investigated thus far...
  59. ncbi request reprint Isolated compression of the pectoral nerve resulting in atrophy of the major pectoral muscle
    Alexander Gardetto
    Department of Plastic and Reconstructive Surgery, Innsbruck University Hospital and Ludwig Boltzmann Institute for Quality Control in Plastic and Reconstructive Surgery, Anichstrasse 35, A 6020 Innsbruck, Austria
    Muscle Nerve 28:760-3. 2003
    ..Early recognition and treatment are vital to prevent associated morbidity of these rare but serious injuries...
  60. ncbi request reprint Chronic infections and the risk of carotid atherosclerosis: prospective results from a large population study
    S Kiechl
    Departments of Neurology, University Clinic Innsbruck, Innsbruck, Austria
    Circulation 103:1064-70. 2001
    ..CONCLUSIONS: The present study provides solid evidence for a role of common chronic infections in human atherogenesis. Induction of systemic inflammation and autoimmunity may be potential pathophysiological links...
  61. ncbi request reprint The prevalence of primary dystonia in the general community
    J Muller
    University Hospital of Neurology, Innsbruck, Austria
    Neurology 59:941-3. 2002
    ..Only two cases (33%) had been previously diagnosed. These results indicate that the true prevalence of primary dystonia is significantly higher than published rates...
  62. ncbi request reprint Parkinsonism following striatal infarcts: incidence in a prospective stroke unit cohort
    C Peralta
    Department of Neurology, University of Innsbruck, Innsbruck, Austria
    J Neural Transm 111:1473-83. 2004
    ..Overall, parkinsonism does not appear to be a frequent consequence of striatal infarcts. Multiple lacunar subcortical infarcts interrupting thalamocortical drive may be more critical for the development of vascular parkinsonism...
  63. doi request reprint Basilar artery dissection: series of 12 consecutive cases and review of the literature
    M Ruecker
    Department of Neurology, Innsbruck Medical University, Innsbruck, Austria
    Cerebrovasc Dis 30:267-76. 2010
    ..Current knowledge on primary or isolated basilar artery dissection (IBAD) is limited to case vignettes and small patient series...
  64. doi request reprint Prevalence of primary headaches and cranial neuralgias in men and women aged 55-94 years (Bruneck Study)
    J Schwaiger
    Department of Neurology, Innsbruck Medical University, Innsbruck, Austria
    Cephalalgia 29:179-87. 2009
    ....
  65. ncbi request reprint Restless legs syndrome: a community-based study of prevalence, severity, and risk factors
    B Hogl
    Department of Neurology, Innsbruck Medical University, Anichstr 35, 6020 Innsbruck, Austria
    Neurology 64:1920-4. 2005
    ..To assess the prevalence and severity of restless legs syndrome (RLS) in the general community and to investigate its potential relationship with iron metabolism and other potential risk factors...
  66. ncbi request reprint Recanalization after thrombolysis in stroke patients: predictors and prognostic implications
    A Zangerle
    Department of Neurology, Innsbruck Medical University, Anichstrasse 35, 6020 Innsbruck, Austria
    Neurology 68:39-44. 2007
    ..To estimate rates, predictors, and prognostic importance of recanalization in an unselected series of patients with stroke treated with IV thrombolysis...
  67. pmc Living at high altitude and risk of hospitalisation for atopic asthma in children: results from a large prospective birth-cohort study
    U Kiechl-Kohlendorfer
    Department of Paediatrics, Division of Neonatology, Innsbruck Medical University, Innsbruck, Austria
    Arch Dis Child 92:339-42. 2007
    ..This study will focus on the altitude of residence...
  68. ncbi request reprint Population-based incidence rates and risk factors for type 2 diabetes in white individuals: the Bruneck study
    Enzo Bonora
    Division of Endocrinology and Metabolic Diseases, University of Verona Medical School, Verona, Italy
    Diabetes 53:1782-9. 2004
    ....
  69. ncbi request reprint Carotid atherosclerosis and coronary heart disease in the metabolic syndrome: prospective data from the Bruneck study
    Enzo Bonora
    Division of Endocrinology and Metabolic Diseases, University of Verona Medical School, Verona, Italy
    Diabetes Care 26:1251-7. 2003
    ..The present study aimed at prospectively evaluating carotid atherosclerosis and coronary heart disease (CHD) in subjects with the metabolic syndrome...
  70. ncbi request reprint Association of serum-soluble heat shock protein 60 with carotid atherosclerosis: clinical significance determined in a follow-up study
    Qingzhong Xiao
    Department of Cardiac and Vascular Sciences, St George s University of London, United Kingdom
    Stroke 36:2571-6. 2005
    ..In the current evaluation, we tested the hypothesis that sHSP60 levels are associated with the progression of carotid arteriosclerosis, prospectively...
  71. ncbi request reprint Oxidized phospholipids predict the presence and progression of carotid and femoral atherosclerosis and symptomatic cardiovascular disease: five-year prospective results from the Bruneck study
    Sotirios Tsimikas
    Department of Medicine, University of California San Diego, La Jolla, California 92093 0682, USA
    J Am Coll Cardiol 47:2219-28. 2006
    ..The purpose of this work was to determine the predictive value of oxidized phospholipids (OxPLs) present on apolipoprotein B-100 particles (apoB) in carotid and femoral atherosclerosis...
  72. ncbi request reprint Oxidized low-density lipoprotein autoantibodies, chronic infections, and carotid atherosclerosis in a population-based study
    Manuel Mayr
    Department of Cardiac and Vascular Sciences, St George s, University of London, London, United Kingdom
    J Am Coll Cardiol 47:2436-43. 2006
    ..We investigated whether associations exist between immune reactions to oxidized low-density lipoproteins (OxLDLs), chronic infections, and carotid atherosclerosis as quantified by ultrasound...
  73. ncbi request reprint Genetic and acquired inflammatory conditions are synergistically associated with early carotid atherosclerosis
    Hugh S Markus
    Centre for Clinical Neuroscience, Department of Cardiac and Vascular Sciences, St George s University of London, UK
    Stroke 37:2253-9. 2006
    ..We replicated this finding in a second large population and extended the analysis by inclusion of other inflammatory conditions (chronic infection and obesity/abnormal glucose tolerance)...
  74. ncbi request reprint High-sensitivity C-reactive protein and risk of nontraumatic fractures in the Bruneck study
    Georg Schett
    Department of Internal Medicine III and Institute for Clinical Immunology, University of Erlangen Nuremberg, Erlangen, Germany
    Arch Intern Med 166:2495-501. 2006
    ..It is unknown, however, whether low-grade inflammation in healthy individuals, as estimated by the high-sensitivity C-reactive protein (hs-CRP) level, interferes with bone metabolism and affects the risk of nontraumatic fractures...
  75. ncbi request reprint Insulin resistance as estimated by homeostasis model assessment predicts incident symptomatic cardiovascular disease in caucasian subjects from the general population: the Bruneck study
    Enzo Bonora
    Endocrinologia e Malattie del Metabolismo, Ospedale Maggiore, Piazzale Stefani 1, 37126 Verona, Italy
    Diabetes Care 30:318-24. 2007
    ....
  76. doi request reprint Common CCR5-del32 frameshift mutation associated with serum levels of inflammatory markers and cardiovascular disease risk in the Bruneck population
    Ali R Afzal
    Department of Clinical Developmental Sciences, St George s University of London, London, SW17 ORE, UK
    Stroke 39:1972-8. 2008
    ..The main aim of this study was to examine potential effect of the CCR5-del32 mutation on systemic inflammation, intima-media thickness in carotid and femoral arteries, and on the indices of cardiovascular disease...
  77. doi request reprint Association of genetic variation on chromosome 9p21 with susceptibility and progression of atherosclerosis: a population-based, prospective study
    Shu Ye
    Clinical Pharmacology, William Harvey Research Institute, Barts and the London School of Medicine, London, United Kingdom
    J Am Coll Cardiol 52:378-84. 2008
    ....
  78. ncbi request reprint Soluble RANKL and risk of nontraumatic fracture
    Georg Schett
    Department of Internal Medicine III, Division of Rheumatology, University of Vienna, Vienna, Austria
    JAMA 291:1108-13. 2004
    ..The receptor activator of nuclear factor kappaB ligand (RANKL) is essential for osteoclast and, possibly, osteoblast activation and may represent a key link between bone formation and resorption...
  79. pmc Endothelial progenitor cells, cardiovascular risk factors, cytokine levels and atherosclerosis--results from a large population-based study
    Qingzhong Xiao
    Cardiovascular Division, King s College London, University of London, London, United Kingdom
    PLoS ONE 2:e975. 2007
    ..Finally, we demonstrate a significant inverse association between EPC number and extent of carotid atherosclerosis even though this association was only of moderate strength and not entirely consistent in other vascular territories...
  80. ncbi request reprint Serum leptin level and the risk of nontraumatic fracture
    Georg Schett
    Division of Rheumatology, Department of Internal Medicine III, University of Vienna, Austria
    Am J Med 117:952-6. 2004
  81. ncbi request reprint Cardiovascular protection in haemophilia
    Stefan Kiechl
    Lancet 362:2026. 2003
  82. ncbi request reprint [Stroke prevention in atrial fibrillation -- transfer of study results to the practice]
    Stefan Kiechl
    Wien Klin Wochenschr 116:817-9. 2004