Matthias Horn

Summary

Affiliation: University of Vienna
Country: Austria

Publications

  1. ncbi request reprint Bacterial endosymbionts of free-living amoebae
    Matthias Horn
    Division of Microbial Ecology, Institute of Ecology and Conservation Biology, University of Vienna, Althanstr 14, 1090 Vienna, Austria
    J Eukaryot Microbiol 51:509-14. 2004
  2. doi request reprint Chlamydiae as symbionts in eukaryotes
    Matthias Horn
    Department of Microbial Ecology, University of Vienna, A 1090 Vienna, Austria
    Annu Rev Microbiol 62:113-31. 2008
  3. ncbi request reprint Illuminating the evolutionary history of chlamydiae
    Matthias Horn
    Department of Microbial Ecology, Institute of Ecology and Conservation Biology, University of Vienna, Althanstrasse 14, 1090 Vienna, Austria
    Science 304:728-30. 2004
  4. pmc Diversity of bacterial endosymbionts of environmental acanthamoeba isolates
    Stephan Schmitz-Esser
    Department of Microbial Ecology, University of Vienna, Althanstr 14, 1090 Vienna, Austria
    Appl Environ Microbiol 74:5822-31. 2008
  5. doi request reprint Proteomic analysis reveals a virtually complete set of proteins for translation and energy generation in elementary bodies of the amoeba symbiont Protochlamydia amoebophila
    Barbara S Sixt
    Department of Microbial Ecology, University of Vienna, Vienna, Austria
    Proteomics 11:1868-92. 2011
  6. doi request reprint High genetic similarity between two geographically distinct strains of the sulfur-oxidizing symbiont 'Candidatus Thiobios zoothamnicoli'
    Christian Rinke
    Department of Marine Biology, University of Vienna, Vienna, Austria
    FEMS Microbiol Ecol 67:229-41. 2009
  7. pmc The genome of the amoeba symbiont "Candidatus Amoebophilus asiaticus" reveals common mechanisms for host cell interaction among amoeba-associated bacteria
    Stephan Schmitz-Esser
    Department of Microbial Ecology, University of Vienna, Vienna, Austria
    J Bacteriol 192:1045-57. 2010
  8. pmc Lawsonia intracellularis contains a gene encoding a functional rickettsia-like ATP/ADP translocase for host exploitation
    Stephan Schmitz-Esser
    Universitat Wien, Department für Mikrobielle Okologie, Althanstr 14, A 1090 Vienna, Austria
    J Bacteriol 190:5746-52. 2008
  9. pmc Identification and characterization of a novel porin family highlights a major difference in the outer membrane of chlamydial symbionts and pathogens
    Karin Aistleitner
    Department of Microbial Ecology, University of Vienna, Vienna, Austria
    PLoS ONE 8:e55010. 2013
  10. pmc Unity in variety--the pan-genome of the Chlamydiae
    Astrid Collingro
    Department of Microbial Ecology, University of Vienna, Vienna, Austria
    Mol Biol Evol 28:3253-70. 2011

Collaborators

Detail Information

Publications53

  1. ncbi request reprint Bacterial endosymbionts of free-living amoebae
    Matthias Horn
    Division of Microbial Ecology, Institute of Ecology and Conservation Biology, University of Vienna, Althanstr 14, 1090 Vienna, Austria
    J Eukaryot Microbiol 51:509-14. 2004
    ..Furthermore, phylogenetic analysis suggested that these mechanisms have been evolved by the ancestor of these amoeba symbionts in interplay with ancient unicellular eukaryotes...
  2. doi request reprint Chlamydiae as symbionts in eukaryotes
    Matthias Horn
    Department of Microbial Ecology, University of Vienna, A 1090 Vienna, Austria
    Annu Rev Microbiol 62:113-31. 2008
    ..Their analysis has contributed to a broader understanding of chlamydial biology and to novel insights into the evolution of these unique microorganisms...
  3. ncbi request reprint Illuminating the evolutionary history of chlamydiae
    Matthias Horn
    Department of Microbial Ecology, Institute of Ecology and Conservation Biology, University of Vienna, Althanstrasse 14, 1090 Vienna, Austria
    Science 304:728-30. 2004
    ..Ancient chlamydiae appear to be the originators of mechanisms for the exploitation of eukaryotic cells...
  4. pmc Diversity of bacterial endosymbionts of environmental acanthamoeba isolates
    Stephan Schmitz-Esser
    Department of Microbial Ecology, University of Vienna, Althanstr 14, 1090 Vienna, Austria
    Appl Environ Microbiol 74:5822-31. 2008
    ..This study provides evidence for the existence of only a small number of phylogenetically well-separated groups of obligate intracellular endosymbionts of acanthamoebae with global distribution...
  5. doi request reprint Proteomic analysis reveals a virtually complete set of proteins for translation and energy generation in elementary bodies of the amoeba symbiont Protochlamydia amoebophila
    Barbara S Sixt
    Department of Microbial Ecology, University of Vienna, Vienna, Austria
    Proteomics 11:1868-92. 2011
    ..amoebophila exploits its additional genetic repertoire (compared with the Chlamydiaceae), and that its elementary bodies are remarkably well equipped with proteins involved in transcription, translation, and energy generation...
  6. doi request reprint High genetic similarity between two geographically distinct strains of the sulfur-oxidizing symbiont 'Candidatus Thiobios zoothamnicoli'
    Christian Rinke
    Department of Marine Biology, University of Vienna, Vienna, Austria
    FEMS Microbiol Ecol 67:229-41. 2009
    ..niveum with Cand. Thiobios zoothamnicoli is very specific as well as temporally and spatially stable...
  7. pmc The genome of the amoeba symbiont "Candidatus Amoebophilus asiaticus" reveals common mechanisms for host cell interaction among amoeba-associated bacteria
    Stephan Schmitz-Esser
    Department of Microbial Ecology, University of Vienna, Vienna, Austria
    J Bacteriol 192:1045-57. 2010
    ....
  8. pmc Lawsonia intracellularis contains a gene encoding a functional rickettsia-like ATP/ADP translocase for host exploitation
    Stephan Schmitz-Esser
    Universitat Wien, Department für Mikrobielle Okologie, Althanstr 14, A 1090 Vienna, Austria
    J Bacteriol 190:5746-52. 2008
    ..The occurrence of an ATP/ADP translocase in L. intracellularis is explained by a relatively recent horizontal gene transfer event with rickettsiae as donors...
  9. pmc Identification and characterization of a novel porin family highlights a major difference in the outer membrane of chlamydial symbionts and pathogens
    Karin Aistleitner
    Department of Microbial Ecology, University of Vienna, Vienna, Austria
    PLoS ONE 8:e55010. 2013
    ..amoebophila. This work contributes to our understanding of the adaptations of symbiotic and pathogenic chlamydiae to their different eukaryotic hosts...
  10. pmc Unity in variety--the pan-genome of the Chlamydiae
    Astrid Collingro
    Department of Microbial Ecology, University of Vienna, Vienna, Austria
    Mol Biol Evol 28:3253-70. 2011
    ....
  11. pmc Bacteriocyte-associated gammaproteobacterial symbionts of the Adelges nordmannianae/piceae complex (Hemiptera: Adelgidae)
    Elena R Toenshoff
    Department of Microbial Ecology, University of Vienna, Vienna, Austria
    ISME J 6:384-96. 2012
    ..adelgidicola' is an evolutionarily young bacteriocyte-associated symbiont, which has been acquired after diversification of adelgids from their aphid sister group...
  12. pmc "Candidatus Thiobios zoothamnicoli," an ectosymbiotic bacterium covering the giant marine ciliate Zoothamnium niveum
    Christian Rinke
    Department of Marine Biology, University of Vienna, Althanstrasse 14, 1090 Vienna, Austria
    Appl Environ Microbiol 72:2014-21. 2006
    ..The taxonomic status "Candidatus Thiobios zoothamnicoli" is proposed for the ectosymbiont of Z. niveum based on its ultrastructure, its 16S rRNA gene, the intergenic spacer region, and its partial 23S rRNA gene sequence...
  13. ncbi request reprint 'Candidatus Protochlamydia amoebophila', an endosymbiont of Acanthamoeba spp
    Astrid Collingro
    Department of Microbial Ecology, University of Vienna, 1090 Vienna, Austria
    Int J Syst Evol Microbiol 55:1863-6. 2005
    ..8%, respectively), observed in this analysis justify its classification in a new genus. Therefore, the name 'Candidatus Protochlamydia amoebophila' is proposed for the designation of the Acanthamoeba sp. symbiont UWE25 (=ATCC PRA-7)...
  14. pmc An Acanthamoeba sp. containing two phylogenetically different bacterial endosymbionts
    Eva Heinz
    Department of Microbial Ecology, Faculty of Life Sciences, University of Vienna, A 1090 Vienna, Austria
    Environ Microbiol 9:1604-9. 2007
    ..Further analysis of this stable relationship should provide novel insights into the complex interactions of intracellular multiple-partner associations...
  15. pmc Nucleotide parasitism by Simkania negevensis (Chlamydiae)
    Silvia Knab
    Department of Microbial Ecology, University of Vienna, Althanstrasse 14, 1090 Vienna, Austria
    J Bacteriol 193:225-35. 2011
    ..Although similar to other chlamydiae, these transporters show distinct and unique adaptations with respect to substrate specificities and mode of transport...
  16. pmc ATP/ADP translocases: a common feature of obligate intracellular amoebal symbionts related to Chlamydiae and Rickettsiae
    Stephan Schmitz-Esser
    Abteilung Mikrobielle Okologie, Universitat Wien, A 1090 Vienna, Austria
    J Bacteriol 186:683-91. 2004
    ....
  17. doi request reprint Co-evolution and symbiont replacement shaped the symbiosis between adelgids (Hemiptera: Adelgidae) and their bacterial symbionts
    Elena R Toenshoff
    Department of Microbial Ecology, University of Vienna, Althanstrasse 14, Vienna, Austria
    Environ Microbiol 14:1284-95. 2012
    ....
  18. pmc Comparative genomics suggests an independent origin of cytoplasmic incompatibility in Cardinium hertigii
    Thomas Penz
    Department of Microbial Ecology, University of Vienna, Vienna, Austria
    PLoS Genet 8:e1003012. 2012
    ..Instead, comparative genomics suggests an independent evolution of CI in Cardinium and Wolbachia and provides a novel context for understanding the mechanistic basis of CI...
  19. pmc Comprehensive in silico prediction and analysis of chlamydial outer membrane proteins reflects evolution and life style of the Chlamydiae
    Eva Heinz
    Department of Microbial Ecology, Faculty of Life Sciences, University of Vienna, Vienna, Austria
    BMC Genomics 10:634. 2009
    ..k.a. Chlamydophila) pneumoniae, Chlamydia (a.k.a. Chlamydophila) caviae, and Protochlamydia amoebophila...
  20. doi request reprint Raman microspectroscopy reveals long-term extracellular activity of Chlamydiae
    Susanne Haider
    Department of Microbial Ecology, University of Vienna, Althanstrasse 14, 1090 Vienna, Austria
    Mol Microbiol 77:687-700. 2010
    ..These findings change our perception of chlamydial biology and reveal that host-free analyses possess a previously not recognized potential for direct experimental access to these elusive microorganisms...
  21. doi request reprint Chlamydia-like bacteria in respiratory samples of community-acquired pneumonia patients
    Susanne Haider
    Department of Microbial Ecology, University of Vienna, Althanstrasse, Vienna, Austria
    FEMS Microbiol Lett 281:198-202. 2008
    ..This study extends previous findings suggesting an association of Chlamydia-like bacteria with respiratory disease, but a causal link between these microorganisms and respiratory tract infections has yet to be established...
  22. ncbi request reprint The genome of the amoeba symbiont "Candidatus Amoebophilus asiaticus" encodes an afp-like prophage possibly used for protein secretion
    Thomas Penz
    Department of Microbial Ecology, University of Vienna, Wien, Austria
    Virulence 1:541-5. 2010
    ..In S. entomophila this system is used to deliver toxins into insect hosts. This putative antifeeding-like prophage might thus represent the missing protein secretion apparatus in A. asiaticus...
  23. ncbi request reprint Recovery of an environmental Chlamydia strain from activated sludge by co-cultivation with Acanthamoeba sp
    Astrid Collingro
    Division of Microbial Ecology, Institute for Ecology and Conservation Biology, University of Vienna, Althanstr 14, 1090 Vienna, Austria
    Microbiology 151:301-9. 2005
    ....
  24. pmc Lack of effective anti-apoptotic activities restricts growth of Parachlamydiaceae in insect cells
    Barbara S Sixt
    Department of Microbial Ecology, University of Vienna, Vienna, Austria
    PLoS ONE 7:e29565. 2012
    ..These findings highlight the importance of the evolution of anti-apoptotic traits for the success of chlamydiae as pathogens of humans and animals...
  25. pmc Systematic spatial bias in DNA microarray hybridization is caused by probe spot position-dependent variability in lateral diffusion
    Doris Steger
    Department of Microbial Ecology, Vienna Ecology Center, Faculty of Life Sciences, University of Vienna, Wien, Austria
    PLoS ONE 6:e23727. 2011
    ..In particular, non-random spatial variations within individual microarray hybridizations are often observed, but the mechanisms underpinning this positional bias remain incompletely explained...
  26. pmc A bacterial genome in transition--an exceptional enrichment of IS elements but lack of evidence for recent transposition in the symbiont Amoebophilus asiaticus
    Stephan Schmitz-Esser
    Department of Microbial Ecology, University of Vienna, Althanstrasse 14, 1090 Vienna, Austria
    BMC Evol Biol 11:270. 2011
    ..The 1.88 Mbp genome of the obligate intracellular amoeba symbiont Amoebophilus asiaticus contains an unusually large number of transposase genes (n = 354; 23% of all genes)...
  27. pmc Inclusion membrane proteins of Protochlamydia amoebophila UWE25 reveal a conserved mechanism for host cell interaction among the Chlamydiae
    Eva Heinz
    University of Vienna, Department of Microbial Ecology, Althanstrasse 14, A 1090 Vienna, Austria
    J Bacteriol 192:5093-102. 2010
    ..amoebophila shows that this strategy for host cell interaction is conserved among the chlamydiae and is used by chlamydial symbionts and pathogens alike...
  28. doi request reprint Proteomic analysis of the outer membrane of Protochlamydia amoebophila elementary bodies
    Eva Heinz
    Department of Microbial Ecology, Faculty of Life Sciences, University of Vienna, Austria
    Proteomics 10:4363-76. 2010
    ..They reveal both fundamental differences and convergent evolution between pathogenic and symbiotic chlamydiae...
  29. pmc Paracatenula, an ancient symbiosis between thiotrophic Alphaproteobacteria and catenulid flatworms
    Harald Ronald Gruber-Vodicka
    Department of Marine Biology, University of Vienna, A 1090 Vienna, Austria
    Proc Natl Acad Sci U S A 108:12078-83. 2011
    ....
  30. ncbi request reprint The Planctomycetes, Verrucomicrobia, Chlamydiae and sister phyla comprise a superphylum with biotechnological and medical relevance
    Michael Wagner
    Department of Microbial Ecology, University of Vienna, Austria
    Curr Opin Biotechnol 17:241-9. 2006
    ..Furthermore, the availability of these genome sequences offered new insights into the evolutionary history of this peculiar group of microbes with major medical, ecological and biotechnological relevance...
  31. ncbi request reprint Fluorescence in situ hybridisation for the identification and characterisation of prokaryotes
    Michael Wagner
    Department of Microbial Ecology, Institute of Ecology and Conservation Biology, University of Vienna, Althanstrasse 14, A 1090 Vienna, Austria
    Curr Opin Microbiol 6:302-9. 2003
    ....
  32. pmc A novel betaproteobacterial agent of gill epitheliocystis in seawater farmed Atlantic salmon (Salmo salar)
    Elena R Toenshoff
    Department of Microbial Ecology, University of Vienna, Vienna, Austria
    PLoS ONE 7:e32696. 2012
    ..In conclusion, this study identified a novel agent of epitheliocystis in sea-farmed Atlantic salmon and demonstrated that these cysts can be caused by bacteria phylogenetically distinct from the Chlamydiae...
  33. pmc probeCheck--a central resource for evaluating oligonucleotide probe coverage and specificity
    Alexander Loy
    Department of Microbial Ecology, Universitat Wien, Althanstrasse 14, A 1090 Wien, Austria
    Environ Microbiol 10:2894-8. 2008
    ..Taken together, these features provide a multifunctional platform with maximal flexibility for the user in the choice of databases and options for the evaluation of published and newly developed probes and primers...
  34. doi request reprint Signature Protein of the PVC Superphylum
    Ilias Lagkouvardos
    Division of Microbial Ecology, Department of Microbiology and Ecosystem Science, University of Vienna, Vienna, Austria
    Appl Environ Microbiol 80:440-5. 2014
    ....
  35. doi request reprint The Pine Bark Adelgid, Pineus strobi, Contains Two Novel Bacteriocyte-Associated Gammaproteobacterial Symbionts
    Elena R Toenshoff
    Department of Microbiology and Ecosystem Science, University of Vienna, Vienna, Austria
    Appl Environ Microbiol 80:878-85. 2014
    ..Our findings lend further support for a complex evolutionary history of the association of adelgids with a phylogenetically diverse set of bacterial symbionts. ..
  36. pmc Integrating metagenomic and amplicon databases to resolve the phylogenetic and ecological diversity of the Chlamydiae
    Ilias Lagkouvardos
    Division of Microbial Ecology, Department of Microbiology and Ecosystem Science, University of Vienna, Vienna, Austria
    ISME J 8:115-25. 2014
    ..Available information on the origin of metagenomic samples indicated that marine environments contain the majority of the newly discovered chlamydial lineages, highlighting this environment as an important chlamydial reservoir. ..
  37. pmc Metabolic features of Protochlamydia amoebophila elementary bodies--a link between activity and infectivity in Chlamydiae
    Barbara S Sixt
    Division of Microbial Ecology, Department of Microbiology and Ecosystem Science, University of Vienna, Vienna, Austria
    PLoS Pathog 9:e1003553. 2013
    ..amoebophila EBs and provide evidence that metabolic activity in the extracellular stage of chlamydiae is of major biological relevance as it is a critical factor affecting maintenance of infectivity...
  38. pmc probeBase--an online resource for rRNA-targeted oligonucleotide probes: new features 2007
    Alexander Loy
    Department für Mikrobielle Okologie, Universitat Wien, Althanstrasse 14, A 1090 Wien, Austria
    Nucleic Acids Res 35:D800-4. 2007
    ..probeBase is freely accessible at http://www.microbial-ecology.net/probebase. Email correspondence can be addressed to probebase@microbial-ecology.net...
  39. pmc Tapping the nucleotide pool of the host: novel nucleotide carrier proteins of Protochlamydia amoebophila
    Ilka Haferkamp
    Pflanzenphysiologie, Technische Universitat Kaiserslautern, Erwin Schrödinger Str, D 67653 Kaiserslautern, Germany
    Mol Microbiol 60:1534-45. 2006
    ..amoebophila in this and previous studies uncovered that these metabolically impaired bacteria are intimately connected with their host cell's metabolism in a surprisingly complex manner...
  40. pmc Enlightening energy parasitism by analysis of an ATP/ADP transporter from chlamydiae
    Oliver Trentmann
    Pflanzenphysiologie, Technische Universitat Kaiserslautern, Kaiserslautern, Germany
    PLoS Biol 5:e231. 2007
    ..Furthermore, functional reconstitution of this essential chlamydial protein paves the way for high-throughput uptake studies in order to screen for specific inhibitors potentially suitable as anti-chlamydial drugs...
  41. pmc Detection and differentiation of chlamydiae by fluorescence in situ hybridization
    Sven Poppert
    Abteilung für Medizinische Mikrobiologie und Hygiene, Universitat Ulm, Ulm, Germany
    Appl Environ Microbiol 68:4081-9. 2002
    ..In contrast to previously established detection methods for chlamydiae, FISH was not susceptible to false-positive results and allows the detection of all recognized chlamydiae in one single step...
  42. ncbi request reprint Obligate bacterial endosymbionts of Acanthamoeba spp. related to the beta-Proteobacteria: proposal of 'Candidatus Procabacter acanthamoebae' gen. nov., sp. nov
    Matthias Horn
    Lehrstuhl fur Mikrobiologie, Technische Universitat Munchen, Freising, Germany
    Int J Syst Evol Microbiol 52:599-605. 2002
    ....
  43. pmc Molecular evidence for a uniform microbial community in sponges from different oceans
    Ute Hentschel
    Institut für Molekulare Infektionsbiologie, Universitat Wurzburg, D 97070 Wurzburg, Germany
    Appl Environ Microbiol 68:4431-40. 2002
    ..A picture emerges where sponges can be viewed as highly concentrated reservoirs of so far uncultured and elusive marine microorganisms...
  44. pmc The genus Caedibacter comprises endosymbionts of Paramecium spp. related to the Rickettsiales (Alphaproteobacteria) and to Francisella tularensis (Gammaproteobacteria)
    Cora L Beier
    Lehrstuhl fur Mikrobiologie, Technische Universitat Munchen, D 85350 Freising, Germany
    Appl Environ Microbiol 68:6043-50. 2002
    ..caryophilus lived within acanthamoebae prior to the infection of paramecia...
  45. pmc probeBase: an online resource for rRNA-targeted oligonucleotide probes
    Alexander Loy
    Lehrstuhl fur Mikrobiologie, Technische Universitat Munchen, Am Hochanger 4, D 85350 Freising, Germany
    Nucleic Acids Res 31:514-6. 2003
    ..Furthermore, the 'search target site' option provides guidance for the development of new FISH probes...
  46. pmc Discovery of the novel candidate phylum "Poribacteria" in marine sponges
    Lars Fieseler
    Zentrum für Infektionsforschung, Universitat Wurzburg, D 97070 Wuerzburg, Germany
    Appl Environ Microbiol 70:3724-32. 2004
    ..In addition to a report for Planctomycetes, this is the second report of cell compartmentalization, a feature that was considered exclusive to the eukaryotic domain, in prokaryotes...
  47. ncbi request reprint A candidate NAD+ transporter in an intracellular bacterial symbiont related to Chlamydiae
    Ilka Haferkamp
    Pflanzenphysiologie, Universitat Kaiserslautern, D 67653 Kaiserslautern, Germany
    Nature 432:622-5. 2004
    ..This protein acts together with a newly discovered nucleotide transporter and an ATP/ADP translocase, and allows UWE25 to exploit its host cell by means of a sophisticated metabolic parasitism...
  48. pmc Amoebae as training grounds for intracellular bacterial pathogens
    Maelle Molmeret
    Department of Microbiology and Immunology, University of Louisville, Louisville, KY 40202, USA
    Appl Environ Microbiol 71:20-8. 2005
  49. ncbi request reprint Deciphering the evolution and metabolism of an anammox bacterium from a community genome
    Marc Strous
    Department of Microbiology, IWWR, Radboud University Nijmegen, Toernooiveld 1, 6525 ED Nijmegen, The Netherlands
    Nature 440:790-4. 2006
    ..Most significantly, we identified candidate genes responsible for ladderane biosynthesis and biological hydrazine metabolism, and discovered unexpected metabolic versatility...
  50. pmc The isotope array, a new tool that employs substrate-mediated labeling of rRNA for determination of microbial community structure and function
    Justyna Adamczyk
    Lehrstuhl fur Mikrobiologie, Technische Universitat Munchen, D 85350 Freising, Germany
    Appl Environ Microbiol 69:6875-87. 2003
    ....
  51. ncbi request reprint Molecular analysis of bacteria in periodontitis: evaluation of clone libraries, novel phylotypes and putative pathogens
    Gerhard Hutter
    Institute for Hygiene, University of Wurzburg, Germany
    Microbiology 149:67-75. 2003
    ....
  52. ncbi request reprint Various bacterial pathogens and symbionts infect the amoeba Dictyostelium discoideum
    Carina Skriwan
    Institut für Molekulare Infektionsbiologie, Universitat Wurzburg, Germany
    Int J Med Microbiol 291:615-24. 2002
    ..The observed subcellular locations which correspond to the locations within the respective natural hosts suggest that D. discoideum is a representative model system for these pathogens and symbionts...
  53. ncbi request reprint Novel chlamydiae in whiteflies and scale insects: endosymbionts 'Candidatus Fritschea bemisiae' strain Falk and 'Candidatus Fritschea eriococci' strain Elm
    Karin D E Everett
    Department of Biology, University of Washington, Seattle, WA 98195 5325, USA
    Int J Syst Evol Microbiol 55:1581-7. 2005
    ..We concluded that it was appropriate to propose 'Candidatus Fritschea bemisiae' strain Falk and 'Candidatus Fritschea eriococci' strain Elm as members of the family Simkaniaceae in the Chlamydiales...