Alex Hofer

Summary

Affiliation: University of Innsbruck
Country: Austria

Publications

  1. ncbi Neural substrates for episodic encoding and recognition of unfamiliar faces
    Alex Hofer
    Medical University Innsbruck, Department of Biological Psychiatry, Anichstrasse 35, A 6020 Innsbruck, Austria
    Brain Cogn 63:174-81. 2007
  2. ncbi Patient outcomes in schizophrenia II: the impact of cognition
    Alex Hofer
    Department of Biological Psychiatry, Innsbruck Medical University, Anichstrasse 35, A 6020 Innsbruck, Austria
    Eur Psychiatry 20:395-402. 2005
  3. ncbi Patient outcomes in schizophrenia I: correlates with sociodemographic variables, psychopathology, and side effects
    Alex Hofer
    Department of Biological Psychiatry, Innsbruck Medical University, Anichstrasse 35, A 6020 Innsbruck, Austria
    Eur Psychiatry 20:386-94. 2005
  4. ncbi Gender differences in regional cerebral activity during the perception of emotion: a functional MRI study
    Alex Hofer
    Medical University Innsbruck, Department of Biological Psychiatry, Anichstrasse 35, A 6020 Innsbruck, Austria
    Neuroimage 32:854-62. 2006
  5. ncbi Sex differences in brain activation patterns during processing of positively and negatively valenced emotional words
    Alex Hofer
    Department of Biological Psychiatry, Medical University Innsbruck, Austria
    Psychol Med 37:109-19. 2007
  6. ncbi Correlates of subjective and functional outcomes in outpatient clinic attendees with schizophrenia and schizoaffective disorder
    Alex Hofer
    Department of Biological Psychiatry, Medical University Innsbruck, Anichstrasse 35, 6020 Innsbruck, Austria
    Eur Arch Psychiatry Clin Neurosci 256:246-55. 2006
  7. ncbi Quality of life in schizophrenia: the impact of psychopathology, attitude toward medication, and side effects
    Alex Hofer
    Department of Biological Psychiatry, Innsbruck University Clinics, Innsbruck, Austria
    J Clin Psychiatry 65:932-9. 2004
  8. ncbi The neural regions sustaining episodic encoding and recognition of objects
    Alex Hofer
    Medical University Innsbruck, Department of Biological Psychiatry, Anichstrasse 35, A 6020 Innsbruck, Austria
    Brain Cogn 63:159-66. 2007
  9. ncbi Neural correlates of episodic encoding and recognition of words in unmedicated patients during an acute episode of schizophrenia: a functional MRI study
    Alex Hofer
    Department of Biological Psychiatry, Innsbruck University Clinics, Austria
    Am J Psychiatry 160:1802-8. 2003
  10. ncbi The safety of clozapine in the treatment of first- and multiple-episode patients with treatment-resistant schizophrenia
    Alex Hofer
    Department of Biological Psychiatry, Innsbruck University Clinics, Innsbruck, Austria
    Int J Neuropsychopharmacol 6:201-6. 2003

Collaborators

Detail Information

Publications38

  1. ncbi Neural substrates for episodic encoding and recognition of unfamiliar faces
    Alex Hofer
    Medical University Innsbruck, Department of Biological Psychiatry, Anichstrasse 35, A 6020 Innsbruck, Austria
    Brain Cogn 63:174-81. 2007
    ..These results support the view that the successful episodic retrieval of newly learned faces is based on a dorsal visual stream mechanism...
  2. ncbi Patient outcomes in schizophrenia II: the impact of cognition
    Alex Hofer
    Department of Biological Psychiatry, Innsbruck Medical University, Anichstrasse 35, A 6020 Innsbruck, Austria
    Eur Psychiatry 20:395-402. 2005
    ..Associations have been found between the severity of cognitive deficits and social dysfunction, impairments in independent living, occupational limitations, and disturbances in quality of life (QOL)...
  3. ncbi Patient outcomes in schizophrenia I: correlates with sociodemographic variables, psychopathology, and side effects
    Alex Hofer
    Department of Biological Psychiatry, Innsbruck Medical University, Anichstrasse 35, A 6020 Innsbruck, Austria
    Eur Psychiatry 20:386-94. 2005
    ..The present cross-sectional study examined the relationships of psychopathology, side effects, and sociodemographic factors with treatment outcomes in terms of patients' quality of life (QOL), functioning, and needs for care...
  4. ncbi Gender differences in regional cerebral activity during the perception of emotion: a functional MRI study
    Alex Hofer
    Medical University Innsbruck, Department of Biological Psychiatry, Anichstrasse 35, A 6020 Innsbruck, Austria
    Neuroimage 32:854-62. 2006
    ..Our findings suggest gender-related neural responses to emotional stimuli and could contribute to the understanding of mechanisms underlying gender-related vulnerability of the prevalence and severity of neuropsychiatric disorders...
  5. ncbi Sex differences in brain activation patterns during processing of positively and negatively valenced emotional words
    Alex Hofer
    Department of Biological Psychiatry, Medical University Innsbruck, Austria
    Psychol Med 37:109-19. 2007
    ..In this study, we used event-related functional magnetic resonance imaging (fMRI) to investigate gender differences in regional cerebral activity during the perception of positive or negative emotions...
  6. ncbi Correlates of subjective and functional outcomes in outpatient clinic attendees with schizophrenia and schizoaffective disorder
    Alex Hofer
    Department of Biological Psychiatry, Medical University Innsbruck, Anichstrasse 35, 6020 Innsbruck, Austria
    Eur Arch Psychiatry Clin Neurosci 256:246-55. 2006
    ..Our observations suggest that subjective and functional outcomes in highly compliant patients are mainly predicted by psychopathological symptoms and unchangeable sociodemographic variables...
  7. ncbi Quality of life in schizophrenia: the impact of psychopathology, attitude toward medication, and side effects
    Alex Hofer
    Department of Biological Psychiatry, Innsbruck University Clinics, Innsbruck, Austria
    J Clin Psychiatry 65:932-9. 2004
    ..Factors deemed relevant in this context include severity of symptoms, antipsychotic-induced side effects, sociodemographic variables, and patients' subjective response to medication...
  8. ncbi The neural regions sustaining episodic encoding and recognition of objects
    Alex Hofer
    Medical University Innsbruck, Department of Biological Psychiatry, Anichstrasse 35, A 6020 Innsbruck, Austria
    Brain Cogn 63:159-66. 2007
    ....
  9. ncbi Neural correlates of episodic encoding and recognition of words in unmedicated patients during an acute episode of schizophrenia: a functional MRI study
    Alex Hofer
    Department of Biological Psychiatry, Innsbruck University Clinics, Austria
    Am J Psychiatry 160:1802-8. 2003
    ..The same procedure was used in this study to investigate unmedicated patients during an acute episode of schizophrenia...
  10. ncbi The safety of clozapine in the treatment of first- and multiple-episode patients with treatment-resistant schizophrenia
    Alex Hofer
    Department of Biological Psychiatry, Innsbruck University Clinics, Innsbruck, Austria
    Int J Neuropsychopharmacol 6:201-6. 2003
    ..With regard to side-effects, we could not find any significant difference between groups. Altogether, response and side-effects to clozapine treatment do not seem to be determined by the chronicity of the disorder...
  11. ncbi An FMRI study of episodic encoding and recognition of words in patients with schizophrenia in remission
    Alex Hofer
    Department of Biological Psychiatry and Radiology, Innsbruck University Clinics, Anichstrasse 35, A 6020 Innsbruck, Austria
    Am J Psychiatry 160:911-8. 2003
    ..Verbal memory deficits are among the most severe cognitive deficits observed in patients with schizophrenia. This study examined patterns of brain activity during episodic encoding and recognition of words in patients with schizophrenia...
  12. ncbi Brain activation patterns during a selective attention test--a functional MRI study in healthy volunteers and unmedicated patients during an acute episode of schizophrenia
    Elisabeth M Weiss
    Department of General Psychiatry, Medical University Innsbruck, Anichstrasse 35, A 6020 Innsbruck, Austria
    Psychiatry Res 154:31-40. 2007
    ..Treatment with second generation antipsychotics may improve executive performance in patients with schizophrenia and facilitate a normalization of functional hypofrontality after symptomatic improvement...
  13. ncbi Compliance in schizophrenia: psychopathology, side effects, and patients' attitudes toward the illness and medication
    Maria A Rettenbacher
    Department of Biological Psychiatry, Innsbruck University Clinics, Innsbruck, Austria
    J Clin Psychiatry 65:1211-8. 2004
    ....
  14. doi Facial emotion recognition and its relationship to symptomatic, subjective, and functional outcomes in outpatients with chronic schizophrenia
    Alex Hofer
    Department of Biological Psychiatry, Medical University Innsbruck, Anichstrasse 35, A 6020 Innsbruck, Austria
    Eur Psychiatry 24:27-32. 2009
    ..These findings suggest that affect recognition is an important aspect of psychosocial functioning in stable outpatients with schizophrenia...
  15. ncbi Alterations of glucose metabolism during treatment with clozapine or amisulpride: results from a prospective 16-week study
    Maria A Rettenbacher
    Department of Biological Psychiatry, Medical University Innsbruck, Innsbruck, Austria
    J Psychopharmacol 21:400-4. 2007
    ..None of these parameters increased significantly in patients treated with amisulpride. This study indicates that treatment with clozapine appears to have a higher risk to lead to metabolic disturbances than amisupride...
  16. ncbi Early changes of plasma lipids during treatment with atypical antipsychotics
    Maria A Rettenbacher
    Department of Biological Psychiatry, Medical University Innsbruck, Innsbruck, Austria
    Int Clin Psychopharmacol 21:369-72. 2006
    ..These results are important with regard to the increased risk for cardiovascular complications in patients with schizophrenia...
  17. ncbi Attitudes of patients with schizophrenia toward placebo-controlled clinical trials
    Martina Hummer
    Department of Biological Psychiatry, Innsbruck University Clinics, Innsbruck, Austria
    J Clin Psychiatry 64:277-81. 2003
    ..Although much is known about the opinions of professionals concerning this issue, so far nothing is known about the opinions of patients who are most affected by the realization of placebo-controlled clinical trials...
  18. doi Facial emotion recognition and its relationship to subjective and functional outcomes in remitted patients with bipolar I disorder
    Christine M Hoertnagl
    General and Social Psychiatry Division, Medical University Innsbruck, Anichstrasse 35, Innsbruck, Austria
    Bipolar Disord 13:537-44. 2011
    ..Difficulties in affect recognition and in emotional experience are a hallmark of BD, but there is little research investigating the consequences of this deficit on the psychosocial status of patients who are in remission...
  19. doi Factors influencing the choice of new generation antipsychotic medication in the treatment of patients with schizophrenia
    Monika Edlinger
    University Clinic of Biological Psychiatry, Department of Psychiatry and Psychotherapy, Medical University Innsbruck, Innsbruck, Austria
    Schizophr Res 113:246-51. 2009
    ..This prospective, naturalistic study investigated the factors influencing physicians' choice of antipsychotic drug therapy in the treatment of patients with schizophrenia...
  20. ncbi Language lateralization in unmedicated patients during an acute episode of schizophrenia: a functional MRI study
    Elisabeth M Weiss
    Department of General Psychiatry, Anichstrasse 35, Innsbruck Medical University, A 6020 Innsbruck, Austria
    Psychiatry Res 146:185-90. 2006
    ..These results suggest that decreased language lateralization is also evident in unmedicated patients experiencing an acute episode of schizophrenia...
  21. ncbi Cognitive impairment in schizophrenia: clinical ratings are not a suitable alternative to neuropsychological testing
    Alex Hofer
    Medical University Innsbruck, Department of Biological Psychiatry, Anichstrasse 35, A 6020 Innsbruck, Austria
    Schizophr Res 92:126-31. 2007
    ..These data clearly show that clinical assessment of cognitive deficits by the PANSS is not a viable alternative to neuropsychological testing to obtain information about cognitive functioning in schizophrenia...
  22. ncbi Association between antipsychotic-induced elevation of liver enzymes and weight gain: a prospective study
    Maria A Rettenbacher
    Department of Biological Psychiatry, Medical University Innsbruck, Anichstrasse, Innsbruck, Austria
    J Clin Psychopharmacol 26:500-3. 2006
    ..We conclude that antipsychotic-induced elevation of liver enzymes is mostly transient and could be associated with weight gain...
  23. ncbi Prolactin levels and sexual adverse effects in patients with schizophrenia during antipsychotic treatment
    Maria A Rettenbacher
    Department of Psychiatry and Psychotherapy, Division of Biological Psychiatry, Medical University Innsbruck, Anichstrasse 35, A 6020 Innsbruck, Austria
    J Clin Psychopharmacol 30:711-5. 2010
    ..Thus, we investigated the correlation of SD and serum prolactin level in patients with schizophrenia during antipsychotic treatment...
  24. ncbi Brain activation patterns during a selective attention test-a functional MRI study in healthy volunteers and patients with schizophrenia
    Elisabeth M Weiss
    Department of Biological Psychiatry, Innsbruck University Clinics, Anichstrasse 35, A 6020 Innsbruck, Austria
    Psychiatry Res 123:1-15. 2003
    ....
  25. ncbi Osteoporosis in patients with schizophrenia
    Martina Hummer
    Department of Biological Psychiatry, Innsbruck University Hospital, Austria
    Am J Psychiatry 162:162-7. 2005
    ..The authors' goals were to investigate the association between schizophrenia and a decrease in bone mineral density and to get more insight into potential underlying pathophysiological mechanisms...
  26. ncbi Brain activation patterns during a verbal fluency test-a functional MRI study in healthy volunteers and patients with schizophrenia
    Elisabeth M Weiss
    Department of Biological Psychiatry, Innsbruck University Clinics, Anichstrasse 35, 6020 Innsbruck, Austria
    Schizophr Res 70:287-91. 2004
    ..These data indicate that high-functioning schizophrenia patients show a reduced language lateralization of the frontal cortex compared to healthy controls...
  27. ncbi QTc variability in schizophrenia patients treated with antipsychotics and healthy controls
    Maria A Rettenbacher
    Department of Biological Psychiatry, Innsbruck University Hospital, A 6020 Innsbruck, Austria
    J Clin Psychopharmacol 25:206-10. 2005
    ....
  28. ncbi Olanzapine induces insulin resistance: results from a prospective study
    Christoph F Ebenbichler
    Department of Medicine, University of Innsbruck, Innsbruck, Austria
    J Clin Psychiatry 64:1436-9. 2003
    ..The aim of this study was to compare glucose metabolism in patients with schizophrenia receiving olanzapine with that in control subjects...
  29. doi Attitudes of patients with schizophrenia and depression towards psychiatric research
    Monika Edlinger
    Medical University Innsbruck, Department of Psychiatry and Psychotherapy, University Clinic of Biological Psychiatry, Anichstrasse 35, A 6020 Innsbruck, Austria
    Psychiatry Res 177:172-6. 2010
    ..Our findings confirm and extend those of other groups. This should encourage psychiatrists at least in academic settings where most of this research has been done to approach patients to take part in clinical research...
  30. doi Treatment of psychotic and behavioral symptoms with clozapine, aripiprazole, and reboxetine in a patient with Huntington's disease
    Monika Edlinger
    Department of Psychiatry and Psychotherapy, Biological Psychiatry Division, Medical University Innsbruck, Innsbruck, Austria
    Int Clin Psychopharmacol 28:214-6. 2013
    ..As chorea was not disabling in our patient, tetrabenazine has not yet been tried. Treatment was safe without any relevant side effects...
  31. doi Theory of mind and its relevance in schizophrenia
    Falko Biedermann
    Biological Psychiatry Division, Department of Psychiatry and Psychotherapy, Medical University Innsbruck, Innsbruck, Austria
    Curr Opin Psychiatry 25:71-5. 2012
    ..In this context, theory of mind (ToM) abilities are of special relevance, and deficits in this area may represent trait markers of schizophrenia...
  32. ncbi Combined clozapine and electroconvulsive therapy in clozapine-resistant schizophrenia: clinical and cognitive outcomes
    Falko Biedermann
    From the Departments of Biological Psychiatry, and General Psychiatry, Medical University of Innsbruck, Innsbruck, Austria
    J ECT 27:e61-2. 2011
    ..The Positive and Negative Syndrome Scale total score decreased, and all cognitive measures improved.Electroconvulsive therapy would seem to be a safe treatment option for treatment-refractory schizophrenia patients...
  33. ncbi Attitudes towards medication in patients with schizophrenia
    Alex Hofer
    Acta Psychiatr Scand 113:161-2. 2006
  34. ncbi The soluble leptin receptor in olanzapine-induced weight gain: results from a prospective study
    Christoph Ebenbichler
    Schizophr Res 75:143-6. 2005
  35. ncbi Worsening of psychosis after replacement of adjunctive valproate with topiramate in a schizophrenia patient
    Alex Hofer
    J Clin Psychiatry 64:1267-8. 2003
  36. ncbi Attitudes toward antipsychotics among outpatient clinic attendees with schizophrenia
    Alex Hofer
    Department of Biologic Psychiatry, University Clinics Innsbruck, Austria
    J Clin Psychiatry 63:49-53. 2002
    ..A cross-sectional study was conducted in patients with schizophrenia who regularly attended an outpatient clinic to examine the impact of psychopathology, side effects, and sociodemographic factors on attitudes toward antipsychotics...
  37. ncbi Quetiapine cross reactivity with urine methadone immunoassays
    Christian G Widschwendter
    Am J Psychiatry 164:172. 2007
  38. ncbi Olanzapine-induced hyperglycemia: role of humoral insulin resistance-inducing factors
    Markus Laimer
    J Clin Psychopharmacol 25:183-5. 2005