Aner Gurvitz

Summary

Affiliation: University of Vienna
Country: Austria

Publications

  1. pmc Predicting the function and subcellular location of Caenorhabditis elegans proteins similar to Saccharomyces cerevisiae beta-oxidation enzymes
    A Gurvitz
    Institut für Biochemie und Molekulare Zellbiologie der Universität Wien and Ludwig Boltzmann Forschungsstelle für Biochemie, Vienna Biocenter, Dr Bohrgasse 9, A 1030 Vienna, Austria
    Yeast 17:188-200. 2000
  2. ncbi Peroxisomal degradation of trans-unsaturated fatty acids in the yeast Saccharomyces cerevisiae
    A Gurvitz
    Institut für Biochemie und Molekulare Zellbiologie der Universität Wien and Ludwig Boltzmann Forschungsstelle für Biochemie, Vienna Biocenter, Dr Bohrgasse 9, A 1030 Vienna, Austria
    J Biol Chem 276:895-903. 2001
  3. ncbi Adr1p-dependent regulation of the oleic acid-inducible yeast gene SPS19 encoding the peroxisomal beta-oxidation auxiliary enzyme 2,4-dienoyl-CoA reductase
    A Gurvitz
    Institut fur Biochemie und Molekulare Zellbiologie, Universität Wien and Ludwig Boltzmann Forschungsstelle für Biochemie, Vienna Biocenter, Dr Bohrgasse 9, A 1030 Vienna, Austria
    Mol Cell Biol Res Commun 4:81-9. 2000
  4. ncbi Saccharomyces cerevisiae Adr1p governs fatty acid beta-oxidation and peroxisome proliferation by regulating POX1 and PEX11
    A Gurvitz
    Institut für Biochemie und Molekulare Zellbiologie der Universität Wien and Ludwig Boltzmann Forschungsstelle für Biochemie, Vienna Biocenter, Dr Bohrgasse 9, A 1030 Vienna, Austria
    J Biol Chem 276:31825-30. 2001
  5. ncbi Degradation of conjugated linoleic acid isomers in the yeast Saccharomyces cerevisiae
    A Gurvitz
    Institut für Biochemie und Molekulare Zellbiologie der Universität Wien and Ludwig Boltzmann Forschungsstelle für Biochemie, Vienna, Austria
    Biochim Biophys Acta 1533:81-5. 2001
  6. ncbi Preliminary characterisation of DML1, an essential Saccharomyces cerevisiae gene related to misato of Drosophila melanogaster
    Aner Gurvitz
    Institut für Biochemie und Molekulare Zellbiologie der Universität Wien and Ludwig Boltzmann Forschungsstelle für Biochemie, Vienna Biocenter, Dr Bohrgasse 9, Austria
    FEMS Yeast Res 2:123-35. 2002
  7. pmc Heterologous expression of mycobacterial proteins in Saccharomyces cerevisiae reveals two physiologically functional 3-hydroxyacyl-thioester dehydratases, HtdX and HtdY, in addition to HadABC and HtdZ
    Aner Gurvitz
    Section of Physiology of Lipid Metabolism, Institute of Physiology, Center for Physiology, Pathophysiology and Immunology, Medical University of Vienna, Vienna, Austria
    J Bacteriol 191:2683-90. 2009
  8. pmc Function of heterologous Mycobacterium tuberculosis InhA, a type 2 fatty acid synthase enzyme involved in extending C20 fatty acids to C60-to-C90 mycolic acids, during de novo lipoic acid synthesis in Saccharomyces cerevisiae
    Aner Gurvitz
    Section of Physiology of Lipid Metabolism, Institute of Physiology, Center for Physiology and Pathophysiology, Medical University of Vienna, Vienna, Austria
    Appl Environ Microbiol 74:5078-85. 2008
  9. pmc Avoiding unscheduled transcription in shared promoters: Saccharomyces cerevisiae Sum1p represses the divergent gene pair SPS18-SPS19 through a midsporulation element (MSE)
    Aner Gurvitz
    Center for Physiology, Pathophysiology and Immunology, Institute of Physiology, Section of Physiology of Lipid Metabolism, Medical University of Vienna, Vienna, Austria
    FEMS Yeast Res 9:821-31. 2009
  10. pmc Caenorhabditis elegans F09E10.3 encodes a putative 3-oxoacyl-thioester reductase of mitochondrial type 2 fatty acid synthase FASII that is functional in yeast
    Aner Gurvitz
    Section of Physiology of Lipid Metabolism, Institute of Physiology, Center for Physiology, Pathophysiology and Immunology, Medical University of Vienna, Vienna, Austria
    J Biomed Biotechnol 2009:235868. 2009

Collaborators

  • J K Hiltunen
  • Markus Kunze
  • R Erdmann
  • Hanspeter Rottensteiner
  • Andreas Hartig
  • Barbara Hamilton
  • Helmut Ruis
  • Elisabeth Koller
  • Juha M Torkko
  • Ivo Volf
  • Franz Koller
  • Mika Ilves
  • Leila Wabnegger
  • Tomi T Airenne
  • Kari T Koivuranta
  • Tuomo Glumoff
  • Alexander J Kastaniotis
  • Luigi Palmieri

Detail Information

Publications20

  1. pmc Predicting the function and subcellular location of Caenorhabditis elegans proteins similar to Saccharomyces cerevisiae beta-oxidation enzymes
    A Gurvitz
    Institut für Biochemie und Molekulare Zellbiologie der Universität Wien and Ludwig Boltzmann Forschungsstelle für Biochemie, Vienna Biocenter, Dr Bohrgasse 9, A 1030 Vienna, Austria
    Yeast 17:188-200. 2000
    ....
  2. ncbi Peroxisomal degradation of trans-unsaturated fatty acids in the yeast Saccharomyces cerevisiae
    A Gurvitz
    Institut für Biochemie und Molekulare Zellbiologie der Universität Wien and Ludwig Boltzmann Forschungsstelle für Biochemie, Vienna Biocenter, Dr Bohrgasse 9, A 1030 Vienna, Austria
    J Biol Chem 276:895-903. 2001
    ..We propose an amendment to the current scheme of the carbon flux through beta-oxidation taking into account the dispensability of beta-oxidation auxiliary enzymes for metabolizing trans double bonds at even-numbered positions...
  3. ncbi Adr1p-dependent regulation of the oleic acid-inducible yeast gene SPS19 encoding the peroxisomal beta-oxidation auxiliary enzyme 2,4-dienoyl-CoA reductase
    A Gurvitz
    Institut fur Biochemie und Molekulare Zellbiologie, Universität Wien and Ludwig Boltzmann Forschungsstelle für Biochemie, Vienna Biocenter, Dr Bohrgasse 9, A 1030 Vienna, Austria
    Mol Cell Biol Res Commun 4:81-9. 2000
    ..We conclude that in the presence of fatty acids in the medium transcription of SPS19 is directly regulated by both Pip2p-Oaf1p and Adr1p...
  4. ncbi Saccharomyces cerevisiae Adr1p governs fatty acid beta-oxidation and peroxisome proliferation by regulating POX1 and PEX11
    A Gurvitz
    Institut für Biochemie und Molekulare Zellbiologie der Universität Wien and Ludwig Boltzmann Forschungsstelle für Biochemie, Vienna Biocenter, Dr Bohrgasse 9, A 1030 Vienna, Austria
    J Biol Chem 276:31825-30. 2001
    ..We conclude that overlapping ORE and UAS1 elements in conjunction with their binding factors Pip2p-Oaf1p and Adr1p coordinate the carbon flux through beta-oxidation with peroxisome proliferation...
  5. ncbi Degradation of conjugated linoleic acid isomers in the yeast Saccharomyces cerevisiae
    A Gurvitz
    Institut für Biochemie und Molekulare Zellbiologie der Universität Wien and Ludwig Boltzmann Forschungsstelle für Biochemie, Vienna, Austria
    Biochim Biophys Acta 1533:81-5. 2001
    ..Cells utilized efficiently trans-10,cis-12 CLA, but not the corresponding cis-9,trans-11 isomer, probably due to the formation of cis-3,trans-5-dienoyl-CoA intermediates that are recalcitrant to beta-oxidation...
  6. ncbi Preliminary characterisation of DML1, an essential Saccharomyces cerevisiae gene related to misato of Drosophila melanogaster
    Aner Gurvitz
    Institut für Biochemie und Molekulare Zellbiologie der Universität Wien and Ludwig Boltzmann Forschungsstelle für Biochemie, Vienna Biocenter, Dr Bohrgasse 9, Austria
    FEMS Yeast Res 2:123-35. 2002
    ..Dml1p might additionally function in the partitioning of the mitochondrial organelle itself, or in the segregation of chromosomes, thereby explaining its essential requirement...
  7. pmc Heterologous expression of mycobacterial proteins in Saccharomyces cerevisiae reveals two physiologically functional 3-hydroxyacyl-thioester dehydratases, HtdX and HtdY, in addition to HadABC and HtdZ
    Aner Gurvitz
    Section of Physiology of Lipid Metabolism, Institute of Physiology, Center for Physiology, Pathophysiology and Immunology, Medical University of Vienna, Vienna, Austria
    J Bacteriol 191:2683-90. 2009
    ....
  8. pmc Function of heterologous Mycobacterium tuberculosis InhA, a type 2 fatty acid synthase enzyme involved in extending C20 fatty acids to C60-to-C90 mycolic acids, during de novo lipoic acid synthesis in Saccharomyces cerevisiae
    Aner Gurvitz
    Section of Physiology of Lipid Metabolism, Institute of Physiology, Center for Physiology and Pathophysiology, Medical University of Vienna, Vienna, Austria
    Appl Environ Microbiol 74:5078-85. 2008
    ..tuberculosis and the potential use of yeast FASII mutants for investigating the physiological function of drug-targeted pathogen enzymes involved in fatty acid biosynthesis...
  9. pmc Avoiding unscheduled transcription in shared promoters: Saccharomyces cerevisiae Sum1p represses the divergent gene pair SPS18-SPS19 through a midsporulation element (MSE)
    Aner Gurvitz
    Center for Physiology, Pathophysiology and Immunology, Institute of Physiology, Section of Physiology of Lipid Metabolism, Medical University of Vienna, Vienna, Austria
    FEMS Yeast Res 9:821-31. 2009
    ....
  10. pmc Caenorhabditis elegans F09E10.3 encodes a putative 3-oxoacyl-thioester reductase of mitochondrial type 2 fatty acid synthase FASII that is functional in yeast
    Aner Gurvitz
    Section of Physiology of Lipid Metabolism, Institute of Physiology, Center for Physiology, Pathophysiology and Immunology, Medical University of Vienna, Vienna, Austria
    J Biomed Biotechnol 2009:235868. 2009
    ..This is the first identification of a metazoan 3-oxoacyl-thioester reductase (see Note Added in Proof)...
  11. pmc A C. elegans model for mitochondrial fatty acid synthase II: the longevity-associated gene W09H1.5/mecr-1 encodes a 2-trans-enoyl-thioester reductase
    Aner Gurvitz
    Section of Physiology of Lipid Metabolism, Institute of Physiology, Center for Physiology, Pathophysiology and Immunology, Medical University of Vienna, Vienna, Austria
    PLoS ONE 4:e7791. 2009
    ..The availability of affected survivors will help to position C. elegans as an excellent model for future pursuits in the emerging field of mitochondrial FASII research...
  12. ncbi Targeting of malate synthase 1 to the peroxisomes of Saccharomyces cerevisiae cells depends on growth on oleic acid medium
    Markus Kunze
    Institut für Biochemie und Molekulare Zellbiologie der Universität Wien and Ludwig Boltzmann Forschungsstelle für Biochemie, Vienna Biocenter, Austria
    Eur J Biochem 269:915-22. 2002
    ..The combined results indicated that Mls1p remained in the cytosol of cells grown on ethanol, and that targeting of Mls1p to the peroxisomes was advantageous to cells grown on oleic acid as a sole carbon source...
  13. pmc Identification of a novel mycobacterial 3-hydroxyacyl-thioester dehydratase, HtdZ (Rv0130), by functional complementation in yeast
    Aner Gurvitz
    Section of Physiology of Lipid Metabolism, Institute of Physiology, Center for Physiology and Pathophysiology, Medical University of Vienna, Vienna, Austria
    J Bacteriol 190:4088-90. 2008
    ..Mutant cells expressing HtdZ contained dehydratase activity, recovered their respiratory ability, and partially restored de novo lipoic acid synthesis...
  14. ncbi The biochemistry of oleate induction: transcriptional upregulation and peroxisome proliferation
    Aner Gurvitz
    Medical University of Vienna, Center of Physiology and Pathophysiology, Department of Physiology, Section of Physiology of Fatty Acid Lipid Metabolism, 1090 Vienna, Austria
    Biochim Biophys Acta 1763:1392-402. 2006
    ....
  15. ncbi Saccharomyces cerevisiae Pip2p-Oaf1p regulates PEX25 transcription through an adenine-less ORE
    Hanspeter Rottensteiner
    Institut fur Physiologische Chemie, Ruhr Universitat Bochum, Germany
    Eur J Biochem 270:2013-22. 2003
    ..These data on a functional, adenine-less, PEX25 ORE and a nonfunctional N13-spaced ORE-like sequence in the PEX14 promoter capable of binding Pip2p-Oaf1p prompts readjustment of the ORE consensus to comprise CGGN3TNA/(R)N8-12CCG...
  16. ncbi The biochemistry of peroxisomal beta-oxidation in the yeast Saccharomyces cerevisiae
    J Kalervo Hiltunen
    Biocenter Oulu and Department of Biochemistry, P O Box 3000, FIN 90014 University of Oulu, Oulu, Finland
    FEMS Microbiol Rev 27:35-64. 2003
    ....
  17. pmc The peroxisomal transporter gene ANT1 is regulated by a deviant oleate response element (ORE): characterization of the signal for fatty acid induction
    Hanspeter Rottensteiner
    FU Berlin, FB Biologie, Chemie, Pharmazie, Thielallee 63, D 14195 Berlin, Germany
    Biochem J 365:109-17. 2002
    ..Generation of the signal was also independent of protein synthesis, as demonstrated by cycloheximide treatment...
  18. ncbi Saccharomyces cerevisiae PIP2 mediating oleic acid induction and peroxisome proliferation is regulated by Adr1p and Pip2p-Oaf1p
    Hanspeter Rottensteiner
    Institut fur Physiologische Chemie, Ruhr Universitat Bochum, D 44780 Bochum, Germany
    J Biol Chem 278:27605-11. 2003
    ..Hence, both the expression as well as the action of the two transcription factors, Adr1p and Pip2p-Oaf1p, are interconnected, which allows for an elaborate control of fatty acid-inducible genes...
  19. ncbi Candida tropicalis expresses two mitochondrial 2-enoyl thioester reductases that are able to form both homodimers and heterodimers
    Juha M Torkko
    Biocenter Oulu, Department of Biochemistry, University of Oulu, Finland
    J Biol Chem 278:41213-20. 2003
    ..Resolving of crystal structures obtained via Etr2p and Etr1p co-crystallization indicated that all possible dimer variants occur in the same asymmetric unit, suggesting that similar dimer formation also takes place in vivo...
  20. ncbi Modified low-density lipoproteins and high-density lipoproteins. From investigation tools to real in vivo players
    Elisabeth Koller
    Department of Physiology, Center of Physiology and Pathophysiology, Medical University of Vienna, Austria
    Pathophysiol Haemost Thromb 35:322-45. 2006
    ..More recently, alterations to lipoproteins performed using hypochloric acid and myeloperoxidase redirected the attention to the role of modified apoproteins in triggering platelet responses...