Research Topics

Christoph A Gebeshuber

Affiliation: University of Vienna

Country: Austria

Beta-catenin/LEF-1 signalling in breast cancer--central players activated by a plethora of inputs
Christoph A Gebeshuber
Institute for Molecular Pathology Vienna, Vienna, Austria
Cells Tissues Organs 185:51-60. 2007
miR-29a suppresses tristetraprolin, which is a regulator of epithelial polarity and metastasis
Christoph A Gebeshuber
IMBA Vienna, Institute for Molecular Pathology, Dr Bohrgasse 3 5, 1030 Vienna, Austria
EMBO Rep 10:400-5. 2009
Annexin A1 attenuates EMT and metastatic potential in breast cancer
Sabine Maschler
Research Institute of Molecular Pathology, Vienna, Austria
EMBO Mol Med 2:401-14. 2010

Beta-catenin/LEF-1 signalling in breast cancer--central players activated by a plethora of inputs
Christoph A Gebeshuber
Institute for Molecular Pathology Vienna, Vienna, Austria
Cells Tissues Organs 185:51-60. 2007
..We want to focus on the Wnt-activated transcription factor complex beta-catenin/LEF-1, its upstream activators, its downstream targets and consequences on the cellular level in response to beta-catenin/LEF-1 activation...
miR-29a suppresses tristetraprolin, which is a regulator of epithelial polarity and metastasis
Christoph A Gebeshuber
IMBA Vienna, Institute for Molecular Pathology, Dr Bohrgasse 3 5, 1030 Vienna, Austria
EMBO Rep 10:400-5. 2009
..Previously, miR-29 family members were shown to have tumour-suppressive effects in haematopoietic, cholangiocytic and lung tumours. Therefore, miRNAs can act as either oncogenes or tumour suppressors, depending on the context...
Annexin A1 attenuates EMT and metastatic potential in breast cancer
Sabine Maschler
Research Institute of Molecular Pathology, Vienna, Austria
EMBO Mol Med 2:401-14. 2010
..AnxA1 knockdown stimulated multiple signalling pathways but only Tyk2/Stat3 and Erk1/2 signalling were essential for EMT...