M Ganzera

Summary

Affiliation: University of Innsbruck
Country: Austria

Publications

  1. ncbi request reprint Quantitative HPLC analysis of withanolides in Withania somnifera
    M Ganzera
    Department of Pharmacognosy, University of Innsbruck, Innsbruck 6020, Austria
    Fitoterapia 74:68-76. 2003
  2. doi request reprint Chemical profiling of Edelweiss (Leontopodium alpinum Cass.) extracts by micellar electrokinetic capillary chromatography
    Markus Ganzera
    Institute of Pharmacy, Pharmacognosy, University of Innsbruck, CCB, Innrain 80 82, 6020 Innsbruck, Austria
    Fitoterapia 83:1680-6. 2012
  3. doi request reprint Quantitative analysis of flavonoids and phenolic acids in Arnica montana L. by micellar electrokinetic capillary chromatography
    Markus Ganzera
    Institute of Pharmacy, Pharmacognosy, University of Innsbruck, Innrain 52, 6020 Innsbruck, Austria
    Anal Chim Acta 614:196-200. 2008
  4. ncbi request reprint Determination of adenine and pyridine nucleotides in glucose-limited chemostat cultures of Penicillium simplicissimum by one-step ethanol extraction and ion-pairing liquid chromatography
    Markus Ganzera
    Institute of Pharmacy, Department of Pharmacognosy, University of Innsbruck, 6020 Innsbruck, Austria
    Anal Biochem 359:132-40. 2006
  5. ncbi request reprint Development and validation of an HPLC/UV/MS method for simultaneous determination of 18 preservatives in grapefruit seed extract
    Markus Ganzera
    Institute of Pharmacy, University of Innsbruck, Innrain 52, 6020 Innsbruck, Austria
    J Agric Food Chem 54:3768-72. 2006
  6. ncbi request reprint Inhibitory effects of the essential oil of chamomile (Matricaria recutita L.) and its major constituents on human cytochrome P450 enzymes
    M Ganzera
    Institute of Pharmacy, Department of Pharmacognosy, University of Innsbruck, Innrain 52, 6020 Innsbruck, Austria
    Life Sci 78:856-61. 2006
  7. ncbi request reprint Differentiation of Cirsium japonicum and C. setosum by TLC and HPLC-MS
    Markus Ganzera
    Department of Pharmacognosy, Institute of Pharmacy, University of Innsbruck, Innrain 52, 6020 Innsbruck, Austria
    Phytochem Anal 16:205-9. 2005
  8. ncbi request reprint Urtica dioica agglutinin: separation, identification, and quantitation of individual isolectins by capillary electrophoresis and capillary electrophoresis-mass spectrometry
    Markus Ganzera
    Department of Pharmacognosy, Institute of Pharmacy, University of Innsbruck, Innrain 52, A 6020 Innsbruck, Austria
    Electrophoresis 26:1724-31. 2005
  9. doi request reprint Quality control of herbal medicines by capillary electrophoresis: potential, requirements and applications
    Markus Ganzera
    Institute of Pharmacy, Pharmacognosy, University of Innsbruck, Innsbruck, Austria
    Electrophoresis 29:3489-503. 2008
  10. ncbi request reprint Simultaneous determination of saponins and isoflavones in soybean (Glycine max L.) by reversed-phase liquid chromatography with evaporative light-scattering and ultraviolet detection
    Markus Ganzera
    University of Innsbruck, Department of Pharmacognosy, Institute of Pharmacy, 6020 Innsbruck, Austria
    J AOAC Int 87:1189-94. 2004

Collaborators

Detail Information

Publications30

  1. ncbi request reprint Quantitative HPLC analysis of withanolides in Withania somnifera
    M Ganzera
    Department of Pharmacognosy, University of Innsbruck, Innsbruck 6020, Austria
    Fitoterapia 74:68-76. 2003
    ..The system was successfully used to investigate the presence of the markers in different W. somnifera plant parts as well as to analyze their content in market products...
  2. doi request reprint Chemical profiling of Edelweiss (Leontopodium alpinum Cass.) extracts by micellar electrokinetic capillary chromatography
    Markus Ganzera
    Institute of Pharmacy, Pharmacognosy, University of Innsbruck, CCB, Innrain 80 82, 6020 Innsbruck, Austria
    Fitoterapia 83:1680-6. 2012
    ..25-0.34%, caffeic acids: 4.99-6.21%, leontopodic acid: 4.21-5.05%)...
  3. doi request reprint Quantitative analysis of flavonoids and phenolic acids in Arnica montana L. by micellar electrokinetic capillary chromatography
    Markus Ganzera
    Institute of Pharmacy, Pharmacognosy, University of Innsbruck, Innrain 52, 6020 Innsbruck, Austria
    Anal Chim Acta 614:196-200. 2008
    ..60 to 1.70%, and 1.03 to 2.24%, respectively...
  4. ncbi request reprint Determination of adenine and pyridine nucleotides in glucose-limited chemostat cultures of Penicillium simplicissimum by one-step ethanol extraction and ion-pairing liquid chromatography
    Markus Ganzera
    Institute of Pharmacy, Department of Pharmacognosy, University of Innsbruck, 6020 Innsbruck, Austria
    Anal Biochem 359:132-40. 2006
    ..Additionally, the effect of the time lag between sampling and extraction and the effect of a glucose pulse on nucleotide concentrations were determined...
  5. ncbi request reprint Development and validation of an HPLC/UV/MS method for simultaneous determination of 18 preservatives in grapefruit seed extract
    Markus Ganzera
    Institute of Pharmacy, University of Innsbruck, Innrain 52, 6020 Innsbruck, Austria
    J Agric Food Chem 54:3768-72. 2006
    ..The samples either contained benzethonium chloride (2.5-176.9 mg/mL) or benzalkonium chloride (138.2-236.3 mg/mL), together with smaller amounts of 4-hydroxybenzoic acid esters, benzoic acid, and salicylic acid...
  6. ncbi request reprint Inhibitory effects of the essential oil of chamomile (Matricaria recutita L.) and its major constituents on human cytochrome P450 enzymes
    M Ganzera
    Institute of Pharmacy, Department of Pharmacognosy, University of Innsbruck, Innrain 52, 6020 Innsbruck, Austria
    Life Sci 78:856-61. 2006
    ....
  7. ncbi request reprint Differentiation of Cirsium japonicum and C. setosum by TLC and HPLC-MS
    Markus Ganzera
    Department of Pharmacognosy, Institute of Pharmacy, University of Innsbruck, Innrain 52, 6020 Innsbruck, Austria
    Phytochem Anal 16:205-9. 2005
    ..83%) was assignable. The HPLC method was validated for linearity, limit of detection (< or = 1.7 ng on-column), peak purity, repeatability (< or = 2.3%) and accuracy (recovery rates of spiked samples were between 99.2 and 101.6%)...
  8. ncbi request reprint Urtica dioica agglutinin: separation, identification, and quantitation of individual isolectins by capillary electrophoresis and capillary electrophoresis-mass spectrometry
    Markus Ganzera
    Department of Pharmacognosy, Institute of Pharmacy, University of Innsbruck, Innrain 52, A 6020 Innsbruck, Austria
    Electrophoresis 26:1724-31. 2005
    ..As for peak resolution, assignable compounds and required separation time the newly developed CE method was clearly advantageous over the determination achieved by LC...
  9. doi request reprint Quality control of herbal medicines by capillary electrophoresis: potential, requirements and applications
    Markus Ganzera
    Institute of Pharmacy, Pharmacognosy, University of Innsbruck, Innsbruck, Austria
    Electrophoresis 29:3489-503. 2008
    ....
  10. ncbi request reprint Simultaneous determination of saponins and isoflavones in soybean (Glycine max L.) by reversed-phase liquid chromatography with evaporative light-scattering and ultraviolet detection
    Markus Ganzera
    University of Innsbruck, Department of Pharmacognosy, Institute of Pharmacy, 6020 Innsbruck, Austria
    J AOAC Int 87:1189-94. 2004
    ..8 and 101.0%, respectively. Different sample matrixes were successfully analyzed, proving the wide range of applicability of this method, including soybeans, capsules, liquids, and instant soy drinks...
  11. doi request reprint Recent advancements and applications in the analysis of traditional Chinese medicines
    Markus Ganzera
    Institute of Pharmacy Pharmacognosy, University of Innsbruck, Innsbruck, Austria
    Planta Med 75:776-83. 2009
    ..Selected examples for currently observable trends will be presented and briefly discussed so that the current status of TCM analysis is clearly visualized...
  12. doi request reprint Application of MEKC and monolithic CEC for the analysis of bioactive naphthoquinones in Eleutherine americana
    Markus Ganzera
    Institute of Pharmacy, Pharmacognosy, University of Innsbruck, Innsbruck, Austria
    Electrophoresis 30:3757-63. 2009
    ..americana samples showed that both methods are suitable for practical applications, because the results were well comparable to those obtained by established techniques such as HPLC...
  13. doi request reprint Determination of quinolizidine alkaloids in different Lupinus species by NACE using UV and MS detection
    Markus Ganzera
    Institute of Pharmacy, Pharmacognosy, University of Innsbruck, Innrain 52, 6020 Innsbruck, Austria
    J Pharm Biomed Anal 53:1231-5. 2010
    ..polyphyllus (3.28% of angustifoline), the content of total alkaloids ranged from 0.43% (L. microcarpus) to 5.13% in L. polyphyllus. The quantitative results were in good agreement with literature data...
  14. ncbi request reprint Analysis of phenolic glycosides and saponins in Primula elatior and Primula veris (primula root) by liquid chromatography, evaporative light scattering detection and mass spectrometry
    Andrea Müller
    Institute of Pharmacy, University of Innsbruck, Innrain 52, 6020 Innsbruck, Austria
    J Chromatogr A 1112:218-23. 2006
    ..The total saponin content was highest in P. veris roots (max. 14.9%), the aerial parts or P. elatior contained significantly less amounts; primeverin (0.64-1.42%) showed to be the most dominant phenolic glycoside...
  15. doi request reprint Hydroxamate siderophores of the ectomycorrhizal fungi Suillus granulatus and S. luteus
    Kurt Haselwandter
    Institut fur Mikrobiologie, Universitat Innsbruck, Technikerstrasse 25, 6020 Innsbruck, Austria
    Biometals 24:153-7. 2011
    ..The potential of these two ectomycorrhizal fungal species to produce siderophores representing three different groups of hydroxamates is discussed in relation to its ecological significance...
  16. ncbi request reprint Quantitative analysis of iridoids, secoiridoids, xanthones and xanthone glycosides in Gentiana lutea L. roots by RP-HPLC and LC-MS
    Anita Aberham
    Institute of Pharmacy, University of Innsbruck, Innrain 52, 6020 Innsbruck, Austria
    J Pharm Biomed Anal 45:437-42. 2007
    ..46-9.53%), followed by loganic acid (0.10-0.76%), swertiamarin (0.21-0.45%) and the xanthone glycosides. Gentisin and isogentisin were found in much lower concentrations between 0.02 and 0.11%, respectively...
  17. ncbi request reprint Transport of sennosides and sennidines from Cassia angustifolia and Cassia senna across Caco-2 monolayers--an in vitro model for intestinal absorption
    B Waltenberger
    Department of Pharmacognosy, Institute of Pharmacy, University of Innsbruck, 6020 Innsbruck, Austria
    Phytomedicine 15:373-7. 2008
    ..Our findings support the general understanding that the laxative effects of Senna are explainable mainly by metabolites and not by the natively present dianthrones...
  18. doi request reprint Analysis of rare flavonoid C-glycosides in Celtis australis L. by micellar electrokinetic chromatography
    Nina Zehrmann
    Institute of Pharmacy, Pharmacognosy, University of Innsbruck, Innrain 52, 6020 Innsbruck, Austria
    J Pharm Biomed Anal 51:1165-8. 2010
    ..The quantitative analysis of several C. australis samples showed that isovitexin is the most abundant representative (0.06-0.09%), at a rather uniform content of total flavonoids of approx. 0.3% in all specimens...
  19. doi request reprint Bioactivity-guided isolation of 1,2,3,4,6-Penta-O-galloyl-D-glucopyranose from Paeonia lactiflora roots as a PTP1B inhibitor
    Renate R Baumgartner
    Department of Pharmacognosy, University of Vienna, Althanstrasse 14, 1090 Vienna, Austria
    J Nat Prod 73:1578-81. 2010
    ..Additionally, 1 was shown to act as an insulin sensitizer in human hepatoma cells (HCC-1.2) at a concentration of 10 μM. Thus, a potential new mechanism of action is provided explaining the antidiabetic properties of P. lactiflora...
  20. doi request reprint Altitudinal variation of secondary metabolite profiles in flowering heads of Matricaria chamomilla cv. BONA
    Markus Ganzera
    Institut fur Pharmazie, Abteilung Pharmakognosie, Universitat Innsbruck, Innsbruck, Austria
    Planta Med 74:453-7. 2008
    ..The results are compared to previous results on Arnica montana L. cv. ARBO. Moreover, various ecological factors, which change with the altitude of the growing site, are discussed as potential causes for the observed variation...
  21. ncbi request reprint Polyacetylenes from the Apiaceae vegetables carrot, celery, fennel, parsley, and parsnip and their cytotoxic activities
    Christian Zidorn
    Abteilung Pharmakognosie, Institut für Pharmazie der Universität Innsbruck, Josef Moeller Haus, Innrain 52, A 6020 Innsbruck, Austria
    J Agric Food Chem 53:2518-23. 2005
    ..5 micromol/L. The possible chemopreventive impact of the presented findings is discussed briefly...
  22. ncbi request reprint HPLC fingerprinting and estimation of the bioactive components of Clutia richardiana L. as a potential hypoglycemic herbal tea
    Ehab A Abourashed
    Department of Pharmacognosy, College of Pharmacy, King Saud University, Riyadh, Saudi Arabia
    Phytother Res 17:657-60. 2003
    ..The aqueous extract was non-toxic against a number of human cell lines, which is a promising indication for its use as a safe and effective antidiabetic herbal preparation...
  23. ncbi request reprint Chemical profiling and standardization of Lepidium meyenii (Maca) by reversed phase high performance liquid chromatography
    Markus Ganzera
    National Center for Natural Products Research, Research Institute of Pharmaceutical Sciences, The University of Mississippi, University 38577, USA
    Chem Pharm Bull (Tokyo) 50:988-91. 2002
    ..The percentage of total markers in the preparations varied from 0.15 to 0.84%, resulting in daily intakes for the consumer from 1.52 to 14.88 mg, respectively...
  24. ncbi request reprint Analysis of naphthoquinone derivatives in the Asian medicinal plant Eleutherine americana by RP-HPLC and LC-MS
    Sompol Paramapojn
    Department of Pharmacognosy, Faculty of Pharmacy, Mahidol University, 447 Sri Ayudhaya Road, Ratchathewi, Bangkok 10400, Thailand
    J Pharm Biomed Anal 47:990-3. 2008
    ..10-0.20%) was dominant in all specimens, followed by isoeleutherin and eleutherin. The new natural product 2,5-dimethyl-10-hydroxynaphthopyrone 8-O-beta-d-glucopyranoside occurred in percentages of less than 0.05%...
  25. ncbi request reprint Determination of naphthazarin derivatives in endemic Turkish Alkanna species by reversed phase high performance liquid chromatography
    Gulseren Pekin
    Department of Bioengineering, Faculty of Engineering, Ege University, Izmir, Turkey
    Planta Med 73:267-72. 2007
    ..04%). Compared to the commonly used A. TINCTORIA (total alkannins: 0.11 to 0.54%; free alkannins: 0.002 to 0.01%) these two species could therefore serve as alternative sources for medicinally important alkannin derivatives...
  26. ncbi request reprint Determination of gentisin, isogentisin, and amarogentin in Gentiana lutea L. by capillary electrophoresis
    Ivana Citová
    Charles University of Prague, Faculty of Pharmacy, Department of Analytical Chemistry, Hradec Kralove, Czech Republic
    J Sep Sci 31:195-200. 2008
    ..lutea samples. Quantitative data obtained with the developed CE method are compared with HPLC results, and the advantages of each approach are discussed...
  27. pmc Novel derivatives of 9,10-anthraquinone are selective algicides against the musty-odor cyanobacterium Oscillatoria perornata
    Kevin K Schrader
    Natural Products Utilization Research Unit, Agricultural Research Service, U S Department of Agriculture, University of Mississippi, University, Mississippi 38677, USA
    Appl Environ Microbiol 69:5319-27. 2003
    ..The half-life of anthraquinone-59 in pond water was determined to be 19 h, making it much less persistent than diuron. Anthraquinone-59 appears to be promising for use as a selective algicide in catfish aquaculture...
  28. ncbi request reprint Alkaloids and saponins in dietary supplements of blue cohosh (Caulophyllum thalictroides)
    Subramaniam Satchithanandam
    U S Food and Drug Administration, Center for Food Safety and Applied Nutrition, Office of Regulatory Science, College Park, MD 20740, USA
    J AOAC Int 91:21-32. 2008
    ..g., root, liquid extract) and doses recommended in product labeling. Intakes may vary from < 1 to 75 mg/day for alkaloids and from about 9 to 420 mg/day for saponins...
  29. ncbi request reprint In vitro plant regeneration from leaf-derived callus of Cimicifuga racemosa
    Hemant Lata
    National Center for Natural Products Research, Research Institute of Pharmaceutical Sciences, School of Pharmacy, The University of Mississippi, University, 38677, USA
    Planta Med 68:912-5. 2002
    ..Activated charcoal was an essential component for vigorous rooting formation. Our results suggest that conservation of C. racemosa is possible through in vitro multiplication of leaf-derived callus...
  30. ncbi request reprint High-performance liquid chromatographic determination of xanthohumol in rat plasma, urine, and fecal samples
    Bharathi Avula
    National Center for Natural Products Research, Research Institute of Pharmaceutical Sciences, The University of Mississippi, MS 38677, USA
    J Chromatogr Sci 42:378-82. 2004
    ..XN and its metabolites are excreted mainly in feces within 24 h of administration. The method is a reliable tool for performing studies of XN in different biological material...