Cem Ekmekcioglu

Summary

Affiliation: University of Vienna
Country: Austria

Publications

  1. ncbi request reprint Cinnamic acid inhibits proliferation and modulates brush border membrane enzyme activities in Caco-2 cells
    C Ekmekcioglu
    Department of Medical Physiology, University of Vienna Medical School, Austria
    Cancer Lett 128:137-44. 1998
  2. ncbi request reprint The melatonin receptor subtype MT2 is present in the human cardiovascular system
    Cem Ekmekcioglu
    Department of Physiology, Faculty of Medicine, University of Vienna, Vienna
    J Pineal Res 35:40-4. 2003
  3. ncbi request reprint Effect of sulfur baths on antioxidative defense systems, peroxide concentrations and lipid levels in patients with degenerative osteoarthritis
    C Ekmekcioglu
    Institut fur Physiologie, Medizinische Fakultat, Universitat Wien
    Forsch Komplementarmed Klass Naturheilkd 9:216-20. 2002
  4. ncbi request reprint Urinary excretion of 8-iso-PGF(2 alpha) in three patients during sepsis, recovery and state of health
    Cem Ekmekcioglu
    Department of Physiology, Medical School, University of Vienna, Vienna, Austria
    Prostaglandins Leukot Essent Fatty Acids 66:441-2. 2002
  5. ncbi request reprint 24h variation in the expression of the mt1 melatonin receptor subtype in coronary arteries derived from patients with coronary heart disease
    C Ekmekcioglu
    Department of Physiology, University of Vienna, Medical School, Austria
    Chronobiol Int 18:973-85. 2001
  6. ncbi request reprint The role of trace elements for the health of elderly individuals
    C Ekmekcioglu
    University of Vienna, Department of Physiology, Schwarzspanierstrasse 17, A 1090 Vienna, Austria
    Nahrung 45:309-16. 2001
  7. ncbi request reprint Expression of the MT1 melatonin receptor subtype in human coronary arteries
    C Ekmekcioglu
    Department of Physiology, University of Vienna, Medical School, Schwarzspanierstrasse 17, A 1090 Vienna, Austria
    J Recept Signal Transduct Res 21:85-91. 2001
  8. ncbi request reprint Intestinal bioavailability of minerals and trace elements from milk and beverages in humans
    C Ekmekcioglu
    University of Vienna, Faculty of Medicine, Institute of Physiology, Schwarzpanierstrasse 17, A 1090 Vienna, Austria
    Nahrung 44:390-7. 2000
  9. ncbi request reprint Magnesium transport from aqueous solutions across Caco-2 cells--an experimental model for intestinal bioavailability studies. Physiological considerations and recommendations
    C Ekmekcioglu
    Department of Medical Physiology, University of Vienna, Austria
    Magnes Res 13:93-102. 2000
  10. ncbi request reprint The plasma membrane Fe(3+)-reductase activity of Caco-2 cells is modulated during differentiation
    C Ekmekcioglu
    Department of Medical Physiology, University of Vienna, Medical School, Austria
    Biochem Mol Biol Int 46:951-61. 1998

Collaborators

Detail Information

Publications36

  1. ncbi request reprint Cinnamic acid inhibits proliferation and modulates brush border membrane enzyme activities in Caco-2 cells
    C Ekmekcioglu
    Department of Medical Physiology, University of Vienna Medical School, Austria
    Cancer Lett 128:137-44. 1998
    ..Intracellular cAMP levels were decreased significantly after 1 h of treatment with 8.0 mM cinnamic acid, suggesting that cinnamic acid induces its effects on enzyme activities partly by modulating the cAMP signaling pathway...
  2. ncbi request reprint The melatonin receptor subtype MT2 is present in the human cardiovascular system
    Cem Ekmekcioglu
    Department of Physiology, Faculty of Medicine, University of Vienna, Vienna
    J Pineal Res 35:40-4. 2003
    ..Furthermore, there is evidence for heterogeneous MT2 expression patterns in individual patients...
  3. ncbi request reprint Effect of sulfur baths on antioxidative defense systems, peroxide concentrations and lipid levels in patients with degenerative osteoarthritis
    C Ekmekcioglu
    Institut fur Physiologie, Medizinische Fakultat, Universitat Wien
    Forsch Komplementarmed Klass Naturheilkd 9:216-20. 2002
    ..Previously it was demonstrated that drinking cures with sulfur can improve the antioxidative defense system and lower the peroxide levels of patients with chronic degenerative osteoarthritis...
  4. ncbi request reprint Urinary excretion of 8-iso-PGF(2 alpha) in three patients during sepsis, recovery and state of health
    Cem Ekmekcioglu
    Department of Physiology, Medical School, University of Vienna, Vienna, Austria
    Prostaglandins Leukot Essent Fatty Acids 66:441-2. 2002
    ....
  5. ncbi request reprint 24h variation in the expression of the mt1 melatonin receptor subtype in coronary arteries derived from patients with coronary heart disease
    C Ekmekcioglu
    Department of Physiology, University of Vienna, Medical School, Austria
    Chronobiol Int 18:973-85. 2001
    ..Furthermore, in relation to our results, we suggest that the expression of the mt1 melatonin receptor in the coronary arteries is probably not impaired in patients with CHD...
  6. ncbi request reprint The role of trace elements for the health of elderly individuals
    C Ekmekcioglu
    University of Vienna, Department of Physiology, Schwarzspanierstrasse 17, A 1090 Vienna, Austria
    Nahrung 45:309-16. 2001
    ....
  7. ncbi request reprint Expression of the MT1 melatonin receptor subtype in human coronary arteries
    C Ekmekcioglu
    Department of Physiology, University of Vienna, Medical School, Schwarzspanierstrasse 17, A 1090 Vienna, Austria
    J Recept Signal Transduct Res 21:85-91. 2001
    ..Referring to these data we assume that melatonin regulates physiological processes in human coronary arteries after receptor binding...
  8. ncbi request reprint Intestinal bioavailability of minerals and trace elements from milk and beverages in humans
    C Ekmekcioglu
    University of Vienna, Faculty of Medicine, Institute of Physiology, Schwarzpanierstrasse 17, A 1090 Vienna, Austria
    Nahrung 44:390-7. 2000
    ..Furthermore this paper also discusses dietary compounds modulating intestinal nutrient bioavailability at the luminal or 8 mucosal level...
  9. ncbi request reprint Magnesium transport from aqueous solutions across Caco-2 cells--an experimental model for intestinal bioavailability studies. Physiological considerations and recommendations
    C Ekmekcioglu
    Department of Medical Physiology, University of Vienna, Austria
    Magnes Res 13:93-102. 2000
    ....
  10. ncbi request reprint The plasma membrane Fe(3+)-reductase activity of Caco-2 cells is modulated during differentiation
    C Ekmekcioglu
    Department of Medical Physiology, University of Vienna, Medical School, Austria
    Biochem Mol Biol Int 46:951-61. 1998
    ..Reagents or hormones affecting cell metabolism through different pathways had no significant effect on this transplasma membrane redox system...
  11. ncbi request reprint Calcium transport from mineral waters across caco-2 cells
    C Ekmekcioglu
    Department of Medical Physiology, Medical School, University of Vienna, A 1090 Vienna, Austria
    J Agric Food Chem 47:2594-9. 1999
    ..On the basis of these results, it can be concluded that calcium bioavailability from mineral waters could vary dependent on probably several factors...
  12. doi request reprint Time dependence of estrogen receptor expression in human hearts
    Valentin Leibetseder
    Department of Physiology, Center of Physiology and Pharmacology, Medical University Vienna, Schwarzspanierstrasse 17, Vienna, Austria
    Biomed Pharmacother 64:154-9. 2010
    ..Furthermore, we provided evidence for a time dependent variation of ERbeta receptor expression in the human heart...
  13. ncbi request reprint Pharmacological levels of copper exert toxic effects in Caco-2 cells
    Bettina Zödl
    Department of Physiology, Faculty of Medicine, University of Vienna, A 1090 Vienna, Austria
    Biol Trace Elem Res 96:143-52. 2003
    ..Risk assessment, especially for high concentrations, might be of special interest...
  14. ncbi request reprint Toxicological effects of iron on intestinal cells
    Bettina Zödl
    Department of Physiology, University of Vienna, Faculty of Medicine, Vienna, Austria
    Cell Biochem Funct 22:143-7. 2004
    ..In conclusion we suggest that iron exerts its toxic effects intracellularly especially in preconfluent Caco-2 cells, whereas only high iron doses were able to alter the viability of differentiating, enterocyte-like cells...
  15. ncbi request reprint Effect of vacation on health: moderating factors of vacation outcome
    Gerhard Strauss-Blasche
    Department of Physiology, Medical University of Vienna, Austria
    J Travel Med 12:94-101. 2005
    ..The present study was aimed at identifying vacation characteristics predicting health-related vacation outcome...
  16. ncbi request reprint The peroxisome proliferator-activated receptor gamma (PPARgamma) is highly expressed in human heart ventricles
    Mohammad R Mehrabi
    Department of Cardiology, General Hospital, Vienna, Austria
    Biomed Pharmacother 56:407-10. 2002
    ..In conclusion, our data argue for the prominent role of PPARgamma in the human heart, particularly in the normal left ventricle...
  17. ncbi request reprint Intestinal transport and metabolism of acrylamide
    Bettina Zödl
    Department of Physiology, Center for Physiology and Pathophysiology, Medical University of Vienna, Schwarzspanierstrasse 17, A 1090 Vienna, Austria
    Toxicology 232:99-108. 2007
    ..Depletion of cellular glutathione levels may be one potential mechanism for acrylamide (geno)toxicity...
  18. doi request reprint Melatonin receptors, melatonin metabolizing enzymes and cyclin D1 in human breast cancer
    Olga Rögelsperger
    Department of Pathophysiology, Center for Pathophysiology and Allergy Research, Medical University of Vienna, Vienna, Austria
    J Recept Signal Transduct Res 31:180-7. 2011
    ..However, metabolism of melatonin via 6-hydroxylation by CYP1A1/1A2 and subsequent sulfonation by SULT1A1/1A3 decreases its intracellular concentration. This could have a negative impact on its oncostatic action in breast cancer...
  19. ncbi request reprint Contribution of individual spa therapies in the treatment of chronic pain
    Gerhard Strauss-Blasche
    Department of Physiology, University of Vienna, Australia
    Clin J Pain 18:302-9. 2002
    ..The aim of the present study was to evaluate the contribution of individual spa therapies administered during a period of 3 weeks on measures of well being and pain in a sample of patients with chronic back pain...
  20. ncbi request reprint Does aerobic training enhance effects of spa therapy in back pain patients? A randomized, controlled clinical trial
    Valentin Leibetseder
    Ludwig Boltzmann Institut zur Erforschung physiologischer Rhythmen, Bad Tatzmannsdorf, Abteilung für Umweltphysiologie, Medizinische Universität Wien, Schwarzspanierstrasse 17, 1090 Vienna, Austria
    Forsch Komplementmed 14:202-6. 2007
    ..The aim of the present study was to evaluate the effects of 3 weeks of individualized aerobic exercise training combined with conventional spa therapy on patients' assessment of chronic pain and quality of life...
  21. ncbi request reprint Toxic and biochemical effects of zinc in Caco-2 cells
    Bettina Zödl
    Department of Physiology, Faculty of Medicine, University of Vienna, Schwarzspanierstrasse 17, A 1090, Vienna, Austria
    J Inorg Biochem 97:324-30. 2003
    ..In conclusion, we suggest that the susceptibility to zinc induced damage is equal in both confluentation groups of Caco-2 cells. Risk assessment for high concentrations seems recommendable...
  22. ncbi request reprint Combined inpatient rehabilitation and spa therapy for breast cancer patients: effects on quality of life and CA 15-3
    Gerhard Strauss-Blasche
    Center of Physiology and Pathophysiology, Medical University of Vienna, Schwarzspanierstrasse 17, 1090 Vienna, Austria
    Cancer Nurs 28:390-8. 2005
    ..Hot mud packs inducing hyperthermia did not affect CA 15-3. In conclusion, the combination of inpatient rehabilitation with spa therapy provides a promising approach for breast cancer rehabilitation...
  23. doi request reprint Expression of estrogen-metabolizing enzymes and estrogen receptors in cholelithiasis gallbladder
    Martin Svoboda
    Institute of Pathophysiology, Center for Physiology, Pathophysiology and Immunology, Medical University of Vienna, A 1090 Vienna, Austria
    Biomed Pharmacother 62:690-6. 2008
    ....
  24. ncbi request reprint Improving homocysteine levels through balneotherapy: effects of sulphur baths
    Valentin Leibetseder
    Department of Physiology, Faculty of Medicine, University of Vienna, Schwarzspanierstrasse 17, Vienna A 1090, Austria
    Clin Chim Acta 343:105-11. 2004
    ..Plasma homocysteine (tHcy) is a risk factor for cardio-vascular diseases. Furthermore it has been associated with antioxidative status. Additionally balneotherapeutic sulphur baths have been shown to influence antioxidative status...
  25. ncbi request reprint Determination of Iron in Caco-2 cells by ET-AAS
    Michaela Zeiner
    Institute of Analytical Chemistry, University of Vienna, Währingerstr 38, 1090, Vienna, Austria
    Anal Bioanal Chem 382:239-42. 2005
    ..The method was developed for iron uptake studies for toxicological purposes...
  26. ncbi request reprint The arylhydrocarbon receptor (AhR), but not the AhR-nuclear translocator (ARNT), is increased in hearts of patients with cardiomyopathy
    Mohammad Reza Mehrabi
    Department of Cardiology, University of Vienna, Austria
    Virchows Arch 441:481-9. 2002
    ..In conclusion, the increased cellular content of AhR in left ventricular specimens from CMP patients suggests a role for AhR in heart disease...
  27. doi request reprint A combination of resveratrol and melatonin exerts chemopreventive effects in N-methyl-N-nitrosourea-induced rat mammary carcinogenesis
    Terézia Kisková
    Institute of Physiology, Center for Physiology and Pharmacology, Medical University Vienna, Schwarzspanierstrasse 17, A 1090 Vienna, Austria
    Eur J Cancer Prev 21:163-70. 2012
    ..Resveratrol in combination with melatonin has some protective effects on NMU-induced rodent breast cancer. Further studies are necessary to confirm these effects of this promising combination...
  28. ncbi request reprint The melatonin receptor subtype MT1 is expressed in human gallbladder epithelia
    Sylvia Aust
    Department of Pathophysiology, University of Vienna, Vienna, Austria
    J Pineal Res 36:43-8. 2004
    ..Therefore, in addition to its profound antioxidative effects in the biliary system, melatonin might also act through MT1-mediated signal transduction pathways. Thereby, it might be involved in the regulation of gallbladder function...
  29. ncbi request reprint Serum lipids responses to a respite from occupational and domestic demands in subjects with varying levels of stress
    Gerhard Strauss-Blasche
    Department of Physiology, University of Vienna, Schwarzspanierstrasse 17, A 1090, Vienna, Austria
    J Psychosom Res 55:521-4. 2003
    ..To investigate the effect of a temporary respite from domestic and job demands on serum lipid concentrations in subjects with high and low levels of perceived demands...
  30. ncbi request reprint Biotransformation of melatonin in human breast cancer cell lines: role of sulfotransferase 1A1
    Sylvia Aust
    Center for Physiology and Pathophysiology, Medical University of Vienna, Vienna, Austria
    J Pineal Res 39:276-82. 2005
    ..In summary, we demonstrate the importance of SULT1A1 for the biotransformation of 6-OHMel in human breast cancer cells. Our data further suggest that tam can modulate melatonin biotransformation...
  31. ncbi request reprint Vacation at moderate and low altitude improves perceived health in individuals with metabolic syndrome
    Gerhard Strauss-Blasche
    Department of Physiology, University of Vienna, Vienna, Austria
    J Travel Med 11:300-4. 2004
    ..The aim of the present study was to study the effect of a 3-week vacation at moderate and low altitude on perceived health in individuals with increased cardiovascular risk...
  32. ncbi request reprint Expression of the melatonin receptor (MT) 1 in benign and malignant human bone tumors
    Cyril D Toma
    Department of Orthopaedic Surgery, Medical University of Vienna, Vienna, Austria
    J Pineal Res 43:206-13. 2007
    ..These data on the abundant expression of MT1-mRNA in human bone tumors and osteosarcoma cells lines suggest an important role for MT1 in bone pathology...
  33. ncbi request reprint Seasonal variation in effect of spa therapy on chronic pain
    Gerhard Strauss-Blasche
    Department of Physiology, University of Vienna, Austria
    Chronobiol Int 19:483-95. 2002
    ..The results suggest that the effects of spa therapy and possibly other related treatments, such as physical and alternative therapies, are subject to seasonal variation...
  34. doi request reprint Short-term effect of macronutrient composition and glycemic index of a yoghurt breakfast on satiety and mood in healthy young men
    Anna Probst
    Institute of Physiology, Center for Physiology and Pharmacology, Medical University of Vienna, Austria
    Forsch Komplementmed 19:247-51. 2012
    ..Conclusion: The glycemic index does not seem to modify satiety in this short-term setting. The similar mental state between low- and high-calorie breakfasts deserves further investigations...
  35. ncbi request reprint Quantitative analysis of peroxisome proliferator-activated receptor gamma (PPARgamma) expression in arteries and hearts of patients with ischaemic or dilated cardiomyopathy
    Mohammad R Mehrabi
    Department of Cardiology, General Hospital AKH, Wahringer Gurtel 18 20, Vienna 1090, Austria
    Eur J Heart Fail 5:733-9. 2003
    ..In conclusion, our observations of increased PPAR mRNA expression in the coronary arteries and left ventricles from CHD and CMP patients suggest an important function of this nuclear receptor in the pathogenesis of heart disease...
  36. ncbi request reprint Cyclosporine a augments P-glycoprotein expression in the regenerating rat liver
    Maria Daoudaki
    Department of Biological Chemistry, Aristotelian University of Thessaloniki Medical School, Greece
    Biol Pharm Bull 26:303-7. 2003
    ..Therefore, induction of P-gp might also be considered in patients receiving CsA after liver transplantation for hepatocellular carcinoma and chemotherapy as an adjuvant treatment for the prevention of tumor recurrence...