Affiliation: University of Vienna
- Cinnamic acid inhibits proliferation and modulates brush border membrane enzyme activities in Caco-2 cellsC Ekmekcioglu
Department of Medical Physiology, University of Vienna Medical School, Austria
Cancer Lett 128:137-44. 1998..Intracellular cAMP levels were decreased significantly after 1 h of treatment with 8.0 mM cinnamic acid, suggesting that cinnamic acid induces its effects on enzyme activities partly by modulating the cAMP signaling pathway...
- Urinary excretion of 8-iso-PGF(2 alpha) in three patients during sepsis, recovery and state of healthCem Ekmekcioglu
Department of Physiology, Medical School, University of Vienna, Vienna, Austria
Prostaglandins Leukot Essent Fatty Acids 66:441-2. 2002....
- The melatonin receptor subtype MT2 is present in the human cardiovascular systemCem Ekmekcioglu
Department of Physiology, Faculty of Medicine, University of Vienna, Vienna
J Pineal Res 35:40-4. 2003..Furthermore, there is evidence for heterogeneous MT2 expression patterns in individual patients...
- 24h variation in the expression of the mt1 melatonin receptor subtype in coronary arteries derived from patients with coronary heart diseaseC Ekmekcioglu
Department of Physiology, University of Vienna, Medical School, Austria
Chronobiol Int 18:973-85. 2001..Furthermore, in relation to our results, we suggest that the expression of the mt1 melatonin receptor in the coronary arteries is probably not impaired in patients with CHD...
- The role of trace elements for the health of elderly individualsC Ekmekcioglu
University of Vienna, Department of Physiology, Schwarzspanierstrasse 17, A 1090 Vienna, Austria
Nahrung 45:309-16. 2001....
- Expression of the MT1 melatonin receptor subtype in human coronary arteriesC Ekmekcioglu
Department of Physiology, University of Vienna, Medical School, Schwarzspanierstrasse 17, A 1090 Vienna, Austria
J Recept Signal Transduct Res 21:85-91. 2001..Referring to these data we assume that melatonin regulates physiological processes in human coronary arteries after receptor binding...
- Intestinal bioavailability of minerals and trace elements from milk and beverages in humansC Ekmekcioglu
University of Vienna, Faculty of Medicine, Institute of Physiology, Schwarzpanierstrasse 17, A 1090 Vienna, Austria
Nahrung 44:390-7. 2000..Furthermore this paper also discusses dietary compounds modulating intestinal nutrient bioavailability at the luminal or 8 mucosal level...
- Magnesium transport from aqueous solutions across Caco-2 cells--an experimental model for intestinal bioavailability studies. Physiological considerations and recommendationsC Ekmekcioglu
Department of Medical Physiology, University of Vienna, Austria
Magnes Res 13:93-102. 2000....
- Calcium transport from mineral waters across caco-2 cellsC Ekmekcioglu
Department of Medical Physiology, Medical School, University of Vienna, A 1090 Vienna, Austria
J Agric Food Chem 47:2594-9. 1999..On the basis of these results, it can be concluded that calcium bioavailability from mineral waters could vary dependent on probably several factors...
- The plasma membrane Fe(3+)-reductase activity of Caco-2 cells is modulated during differentiationC Ekmekcioglu
Department of Medical Physiology, University of Vienna, Medical School, Austria
Biochem Mol Biol Int 46:951-61. 1998..Reagents or hormones affecting cell metabolism through different pathways had no significant effect on this transplasma membrane redox system...
- Effect of sulfur baths on antioxidative defense systems, peroxide concentrations and lipid levels in patients with degenerative osteoarthritisC Ekmekcioglu
Institut fur Physiologie, Medizinische Fakultat, Universitat Wien
Forsch Komplementarmed Klass Naturheilkd 9:216-20. 2002..Previously it was demonstrated that drinking cures with sulfur can improve the antioxidative defense system and lower the peroxide levels of patients with chronic degenerative osteoarthritis...
- Time dependence of estrogen receptor expression in human heartsValentin Leibetseder
Department of Physiology, Center of Physiology and Pharmacology, Medical University Vienna, Schwarzspanierstrasse 17, Vienna, Austria
Biomed Pharmacother 64:154-9. 2010..Additionally, a possible variation of ERmRNA expression in human hearts in respect to time of day was studied...
- Pharmacological levels of copper exert toxic effects in Caco-2 cellsBettina Zödl
Department of Physiology, Faculty of Medicine, University of Vienna, A 1090 Vienna, Austria
Biol Trace Elem Res 96:143-52. 2003..Risk assessment, especially for high concentrations, might be of special interest...
- The peroxisome proliferator-activated receptor gamma (PPARgamma) is highly expressed in human heart ventriclesMohammad R Mehrabi
Department of Cardiology, General Hospital, Vienna, Austria
Biomed Pharmacother 56:407-10. 2002..In conclusion, our data argue for the prominent role of PPARgamma in the human heart, particularly in the normal left ventricle...
- Effect of vacation on health: moderating factors of vacation outcomeGerhard Strauss-Blasche
Department of Physiology, Medical University of Vienna, Austria
J Travel Med 12:94-101. 2005..The present study was aimed at identifying vacation characteristics predicting health-related vacation outcome...
- Toxicological effects of iron on intestinal cellsBettina Zödl
Department of Physiology, University of Vienna, Faculty of Medicine, Vienna, Austria
Cell Biochem Funct 22:143-7. 2004..In conclusion we suggest that iron exerts its toxic effects intracellularly especially in preconfluent Caco-2 cells, whereas only high iron doses were able to alter the viability of differentiating, enterocyte-like cells...
- Intestinal transport and metabolism of acrylamideBettina Zödl
Department of Physiology, Center for Physiology and Pathophysiology, Medical University of Vienna, Schwarzspanierstrasse 17, A 1090 Vienna, Austria
Toxicology 232:99-108. 2007..Depletion of cellular glutathione levels may be one potential mechanism for acrylamide (geno)toxicity...
- Melatonin receptors, melatonin metabolizing enzymes and cyclin D1 in human breast cancerOlga Rögelsperger
Department of Pathophysiology, Center for Pathophysiology and Allergy Research, Medical University of Vienna, Vienna, Austria
J Recept Signal Transduct Res 31:180-7. 2011..However, metabolism of melatonin via 6-hydroxylation by CYP1A1/1A2 and subsequent sulfonation by SULT1A1/1A3 decreases its intracellular concentration. This could have a negative impact on its oncostatic action in breast cancer...
- Contribution of individual spa therapies in the treatment of chronic painGerhard Strauss-Blasche
Department of Physiology, University of Vienna, Australia
Clin J Pain 18:302-9. 2002..The aim of the present study was to evaluate the contribution of individual spa therapies administered during a period of 3 weeks on measures of well being and pain in a sample of patients with chronic back pain...
- Does aerobic training enhance effects of spa therapy in back pain patients? A randomized, controlled clinical trialValentin Leibetseder
Ludwig Boltzmann Institut zur Erforschung physiologischer Rhythmen, Bad Tatzmannsdorf, Abteilung für Umweltphysiologie, Medizinische Universität Wien, Schwarzspanierstrasse 17, 1090 Vienna, Austria
Forsch Komplementmed 14:202-6. 2007..The aim of the present study was to evaluate the effects of 3 weeks of individualized aerobic exercise training combined with conventional spa therapy on patients' assessment of chronic pain and quality of life...
- Combined inpatient rehabilitation and spa therapy for breast cancer patients: effects on quality of life and CA 15-3Gerhard Strauss-Blasche
Center of Physiology and Pathophysiology, Medical University of Vienna, Schwarzspanierstrasse 17, 1090 Vienna, Austria
Cancer Nurs 28:390-8. 2005..Hot mud packs inducing hyperthermia did not affect CA 15-3. In conclusion, the combination of inpatient rehabilitation with spa therapy provides a promising approach for breast cancer rehabilitation...
- Toxic and biochemical effects of zinc in Caco-2 cellsBettina Zödl
Department of Physiology, Faculty of Medicine, University of Vienna, Schwarzspanierstrasse 17, A 1090, Vienna, Austria
J Inorg Biochem 97:324-30. 2003..In conclusion, we suggest that the susceptibility to zinc induced damage is equal in both confluentation groups of Caco-2 cells. Risk assessment for high concentrations seems recommendable...
- Improving homocysteine levels through balneotherapy: effects of sulphur bathsValentin Leibetseder
Department of Physiology, Faculty of Medicine, University of Vienna, Schwarzspanierstrasse 17, Vienna A 1090, Austria
Clin Chim Acta 343:105-11. 2004..Plasma homocysteine (tHcy) is a risk factor for cardio-vascular diseases. Furthermore it has been associated with antioxidative status. Additionally balneotherapeutic sulphur baths have been shown to influence antioxidative status...
- The arylhydrocarbon receptor (AhR), but not the AhR-nuclear translocator (ARNT), is increased in hearts of patients with cardiomyopathyMohammad Reza Mehrabi
Department of Cardiology, University of Vienna, Austria
Virchows Arch 441:481-9. 2002..In conclusion, the increased cellular content of AhR in left ventricular specimens from CMP patients suggests a role for AhR in heart disease...
- Expression of estrogen-metabolizing enzymes and estrogen receptors in cholelithiasis gallbladderMartin Svoboda
Institute of Pathophysiology, Center for Physiology, Pathophysiology and Immunology, Medical University of Vienna, A 1090 Vienna, Austria
Biomed Pharmacother 62:690-6. 2008....
- Determination of Iron in Caco-2 cells by ET-AASMichaela Zeiner
Institute of Analytical Chemistry, University of Vienna, Währingerstr 38, 1090, Vienna, Austria
Anal Bioanal Chem 382:239-42. 2005..The method was developed for iron uptake studies for toxicological purposes...
- A combination of resveratrol and melatonin exerts chemopreventive effects in N-methyl-N-nitrosourea-induced rat mammary carcinogenesisTerézia Kisková
Institute of Physiology, Center for Physiology and Pharmacology, Medical University Vienna, Schwarzspanierstrasse 17, A 1090 Vienna, Austria
Eur J Cancer Prev 21:163-70. 2012..Resveratrol in combination with melatonin has some protective effects on NMU-induced rodent breast cancer. Further studies are necessary to confirm these effects of this promising combination...
- Serum lipids responses to a respite from occupational and domestic demands in subjects with varying levels of stressGerhard Strauss-Blasche
Department of Physiology, University of Vienna, Schwarzspanierstrasse 17, A 1090, Vienna, Austria
J Psychosom Res 55:521-4. 2003..To investigate the effect of a temporary respite from domestic and job demands on serum lipid concentrations in subjects with high and low levels of perceived demands...
- The melatonin receptor subtype MT1 is expressed in human gallbladder epitheliaSylvia Aust
Department of Pathophysiology, University of Vienna, Vienna, Austria
J Pineal Res 36:43-8. 2004..Therefore, in addition to its profound antioxidative effects in the biliary system, melatonin might also act through MT1-mediated signal transduction pathways. Thereby, it might be involved in the regulation of gallbladder function...
- Vacation at moderate and low altitude improves perceived health in individuals with metabolic syndromeGerhard Strauss-Blasche
Department of Physiology, University of Vienna, Vienna, Austria
J Travel Med 11:300-4. 2004..The aim of the present study was to study the effect of a 3-week vacation at moderate and low altitude on perceived health in individuals with increased cardiovascular risk...
- Biotransformation of melatonin in human breast cancer cell lines: role of sulfotransferase 1A1Sylvia Aust
Center for Physiology and Pathophysiology, Medical University of Vienna, Vienna, Austria
J Pineal Res 39:276-82. 2005..In summary, we demonstrate the importance of SULT1A1 for the biotransformation of 6-OHMel in human breast cancer cells. Our data further suggest that tam can modulate melatonin biotransformation...
- Are proinflammatory cytokines involved in an increased risk for depression by unhealthy diets?Cem Ekmekcioglu
Institute of Physiology, Center for Physiology and Pharmacology, Medical University Vienna, Austria
Med Hypotheses 78:337-40. 2012..Therefore the connection between regular consumption of unhealthy foods, chronic inflammation, and increased risk for depression seems plausible...
- Resveratrol enhances the chemopreventive effect of celecoxib in chemically induced breast cancer in ratsTerézia Kisková
Departments of aAnimal Physiology bCell Biology, Institute of Biology and Ecology, Faculty of Science, P J Šafárik University in Košice, Košice cDepartment of Pathology, Jessenius Faculty of Medicine, Commenius University, Martin, Slovak Republic dDepartment of Pathophysiology and Allergy Research, Center for Pathophysiology, Medical University of Vienna eDepartment of Clinical Pharmacy and Diagnostics, University of Vienna, Vienna fInstitute of Environmental Health, Centre for Public Health, Medical University of Vienna, 1090 Vienna, Austria
Eur J Cancer Prev 23:506-13. 2014..In addition, in terms of tumor volume, the combination was more efficient than celecoxib as a single agent...
- Short-term effect of macronutrient composition and glycemic index of a yoghurt breakfast on satiety and mood in healthy young menAnna Probst
Institute of Physiology, Center for Physiology and Pharmacology, Medical University of Vienna, Austria
Forsch Komplementmed 19:247-51. 2012..A second objective was to study the effect of these yoghurt breakfasts on mental state...
- Expression of the melatonin receptor (MT) 1 in benign and malignant human bone tumorsCyril D Toma
Department of Orthopaedic Surgery, Medical University of Vienna, Vienna, Austria
J Pineal Res 43:206-13. 2007..These data on the abundant expression of MT1-mRNA in human bone tumors and osteosarcoma cells lines suggest an important role for MT1 in bone pathology...
- Seasonal variation in effect of spa therapy on chronic painGerhard Strauss-Blasche
Department of Physiology, University of Vienna, Austria
Chronobiol Int 19:483-95. 2002..The results suggest that the effects of spa therapy and possibly other related treatments, such as physical and alternative therapies, are subject to seasonal variation...
- Clock gene expression in different synovial cells of patients with rheumatoid arthritis and osteoarthritisTatjana Becker
Ludwig Boltzmann Cluster for Rheumatology, Balneology and Rehabilitation, Vienna, Austria
Acta Histochem 116:1199-207. 2014..Preliminary experiments suggest that TNF-α seems to be able to modify clock gene expression in synovial fibroblasts. ..
- Quantitative analysis of peroxisome proliferator-activated receptor gamma (PPARgamma) expression in arteries and hearts of patients with ischaemic or dilated cardiomyopathyMohammad R Mehrabi
Department of Cardiology, General Hospital AKH, Wahringer Gurtel 18 20, Vienna 1090, Austria
Eur J Heart Fail 5:733-9. 2003..In conclusion, our observations of increased PPAR mRNA expression in the coronary arteries and left ventricles from CHD and CMP patients suggest an important function of this nuclear receptor in the pathogenesis of heart disease...
- Cyclosporine a augments P-glycoprotein expression in the regenerating rat liverMaria Daoudaki
Department of Biological Chemistry, Aristotelian University of Thessaloniki Medical School, Greece
Biol Pharm Bull 26:303-7. 2003..Therefore, induction of P-gp might also be considered in patients receiving CsA after liver transplantation for hepatocellular carcinoma and chemotherapy as an adjuvant treatment for the prevention of tumor recurrence...