A Chott

Summary

Affiliation: University of Vienna
Country: Austria

Publications

  1. ncbi Diffuse large B-cell lymphomas with plasmablastic/plasmacytoid features are associated with TP53 deletions and poor clinical outcome
    I Simonitsch-Klupp
    Department of Clinical Pathology, University of Vienna, Vienna, Austria
    Leukemia 18:146-55. 2004
  2. ncbi [Pathology of intestinal lymphomas]
    A Chott
    Klinisches Institut für Pathologie der Universität Wien, Allgemeines Krankenhaus, Vienna, Austria
    Pathologe 24:15-27. 2003
  3. ncbi Morphologic and immunophenotypic properties of neoplastic cells in a case of mast cell sarcoma
    Andreas Chott
    Department of Pathology, University of Vienna, Vienna, Austria
    Am J Surg Pathol 27:1013-9. 2003
  4. ncbi Chemotherapy with cyclophosphamide, doxorubicin, etoposide, vincristine and prednisone (CHOEP) is not effective in patients with enteropathy-type intestinal T-cell lymphoma
    S Wohrer
    Department of Internal Medicine I, Division of Oncology, University of Vienna, Vienna, Austria
    Ann Oncol 15:1680-3. 2004
  5. doi Chronic autoimmune thyroiditis (Hashimoto's thyroiditis) in patients with MALT lymphoma
    M Troch
    Division of Oncology, Department of Internal Medicine I, University of Vienna, Vienna, Austria
    Ann Oncol 19:1336-9. 2008
  6. ncbi Rituximab, cyclophosphamide, doxorubicin, vincristine and prednisone (R-CHOP) for treatment of early-stage gastric diffuse large B-cell lymphoma
    S Wohrer
    Department of Internal Medicine I, Division of Oncology, Center of Excellence in Clinical and Experimental Oncology CLEXO, University of Vienna, Vienna, Austria
    Ann Oncol 15:1086-90. 2004
  7. ncbi Impaired response of gastric MALT-lymphoma to Helicobacter pylori eradication in patients with autoimmune disease
    M Raderer
    Department of Internal Medicine I, University of Vienna, Austria
    Ann Oncol 12:937-9. 2001
  8. pmc Importance of extensive staging in patients with mucosa-associated lymphoid tissue (MALT)-type lymphoma
    M Raderer
    Department of Internal Medicine I, University of Vienna, Austria
    Br J Cancer 83:454-7. 2000
  9. pmc MALT lymphoma associated genetic aberrations occur at different frequencies in primary and secondary intestinal MALT lymphomas
    B Streubel
    Department of Pathology, Medical University of Vienna, Waehringer Guertel 18 20, A 1090 Vienna, Austria
    Gut 55:1581-5. 2006
  10. ncbi A case of 'smouldering' mastocytosis with high mast cell burden, monoclonal myeloid cells, and C-KIT mutation Asp-816-Val
    J H Jordan
    Department of Internal Medicine I, Division of Hematology and Hemostaseology, University of Vienna, Vienna, Austria
    Leuk Res 25:627-34. 2001

Collaborators

Detail Information

Publications101 found, 100 shown here

  1. ncbi Diffuse large B-cell lymphomas with plasmablastic/plasmacytoid features are associated with TP53 deletions and poor clinical outcome
    I Simonitsch-Klupp
    Department of Clinical Pathology, University of Vienna, Vienna, Austria
    Leukemia 18:146-55. 2004
    ..001). Our data indicate a strong association of plasmablastic/plasmacytoid morphology with TP53 deletions, poor response to chemotherapy and short survival...
  2. ncbi [Pathology of intestinal lymphomas]
    A Chott
    Klinisches Institut für Pathologie der Universität Wien, Allgemeines Krankenhaus, Vienna, Austria
    Pathologe 24:15-27. 2003
    ..At any rate, the pathologist must classify the lymphoma according to the WHO classification and diagnoses such as "low-grade B-cell lymphoma" or "small B-cell lymphoma" are not acceptable...
  3. ncbi Morphologic and immunophenotypic properties of neoplastic cells in a case of mast cell sarcoma
    Andreas Chott
    Department of Pathology, University of Vienna, Vienna, Austria
    Am J Surg Pathol 27:1013-9. 2003
    ..Together, neoplastic mast cells in a case of mast cell sarcoma were found to exhibit unique morphologic, phenotypical, and molecular features when compared with mast cells in indolent mastocytosis or normal tissue mast cells...
  4. ncbi Chemotherapy with cyclophosphamide, doxorubicin, etoposide, vincristine and prednisone (CHOEP) is not effective in patients with enteropathy-type intestinal T-cell lymphoma
    S Wohrer
    Department of Internal Medicine I, Division of Oncology, University of Vienna, Vienna, Austria
    Ann Oncol 15:1680-3. 2004
    ..According to promising data with the addition of etoposide (E) to the CHOP regimen (CHOEP) in aggressive lymphomas including T-cell lymphomas, we have treated patients with ETCL with CHOEP chemotherapy...
  5. doi Chronic autoimmune thyroiditis (Hashimoto's thyroiditis) in patients with MALT lymphoma
    M Troch
    Division of Oncology, Department of Internal Medicine I, University of Vienna, Vienna, Austria
    Ann Oncol 19:1336-9. 2008
    ..The percentage and possible association between CAT and extrathyroidal MALT lymphoma, however, have not been assessed so far...
  6. ncbi Rituximab, cyclophosphamide, doxorubicin, vincristine and prednisone (R-CHOP) for treatment of early-stage gastric diffuse large B-cell lymphoma
    S Wohrer
    Department of Internal Medicine I, Division of Oncology, Center of Excellence in Clinical and Experimental Oncology CLEXO, University of Vienna, Vienna, Austria
    Ann Oncol 15:1086-90. 2004
    ..Given the fact that the application of the CD20 antibody rituximab (R) in addition to CHOP has improved outcomes in nodal DLBCL, we have analysed our experience with application of R-CHOP in patients with early-stage gastric DLBCL...
  7. ncbi Impaired response of gastric MALT-lymphoma to Helicobacter pylori eradication in patients with autoimmune disease
    M Raderer
    Department of Internal Medicine I, University of Vienna, Austria
    Ann Oncol 12:937-9. 2001
    ..As clonal expansion of gastric B cells not related to HP has been demonstrated in patients with autoimmune disease (AD), we have analysed whether AD adversely influences response of MALT-lymphoma following HP-eradication...
  8. pmc Importance of extensive staging in patients with mucosa-associated lymphoid tissue (MALT)-type lymphoma
    M Raderer
    Department of Internal Medicine I, University of Vienna, Austria
    Br J Cancer 83:454-7. 2000
    ..In addition, our data suggest that extra-gastrointestinal MALT-type lymphoma more frequently occurs simultaneously at different anatomic sites than MALT-type lymphoma involving the GI-tract...
  9. pmc MALT lymphoma associated genetic aberrations occur at different frequencies in primary and secondary intestinal MALT lymphomas
    B Streubel
    Department of Pathology, Medical University of Vienna, Waehringer Guertel 18 20, A 1090 Vienna, Austria
    Gut 55:1581-5. 2006
    ..The frequency of associated genetic changes was therefore analysed in intestinal MALT lymphoma to determine whether primary and secondary examples may be distinguished by their genetic profile...
  10. ncbi A case of 'smouldering' mastocytosis with high mast cell burden, monoclonal myeloid cells, and C-KIT mutation Asp-816-Val
    J H Jordan
    Department of Internal Medicine I, Division of Hematology and Hemostaseology, University of Vienna, Vienna, Austria
    Leuk Res 25:627-34. 2001
    ..Because of the 'intermediate' clinical signs and absence of progression to aggressive disease, we proposed the term 'smouldering mastocytosis'...
  11. ncbi Immunohistochemical properties of bone marrow mast cells in systemic mastocytosis: evidence for expression of CD2, CD117/Kit, and bcl-x(L)
    J H Jordan
    Department of Internal Medicine I, Division of Hematology and Hemostaseology, University of Vienna, Vienna, Austria
    Hum Pathol 32:545-52. 2001
    ..Apart from these, CD2 may be a novel useful marker because MCs in mastocytosis frequently express this antigen, whereas MCs in other pathologic conditions are CD2 negative...
  12. ncbi MALT lymphoma in patients with autoimmune diseases: a comparative analysis of characteristics and clinical course
    S Wohrer
    Division of Bone Marrow Transplantation, Department of Internal Medicine 1, Medical University of Vienna, Vienna, Austria
    Leukemia 21:1812-8. 2007
    ..The clinical course, however, does not appear to be adversely influenced by the presence of AD, as neither rate of relapse nor times to relapse or survival are significantly different...
  13. ncbi Fas ligand is expressed in normal breast epithelial cells and is frequently up-regulated in breast cancer
    L Mullauer
    Institute of Clinical Pathology, University of Vienna, Vienna
    J Pathol 190:20-30. 2000
    ..These results suggest that increased expression of FasL may confer an advantage on breast cancer cells, possibly by eliminating tumour-infiltrating immune cells, and/or by facilitating tissue destruction during invasion...
  14. pmc Most CD56+ intestinal lymphomas are CD8+CD5-T-cell lymphomas of monomorphic small to medium size histology
    A Chott
    Department of Clinical Pathology, University of Vienna, Austria
    Am J Pathol 153:1483-90. 1998
    ..In contrast to putative NK-cell lymphoma of the sinonasal region, intestinal NK-cell lymphoma seems to be very rare...
  15. ncbi Fas ligand expression in nodal non-Hodgkin's lymphoma
    L Mullauer
    Institute of Clinical Pathology, University of Vienna, AKH General Hospital, Austria
    Mod Pathol 11:369-75. 1998
    ..Apparently, FasL expression is not limited to neoplasms derived from T cells or natural killer cells, and it might play a supporting role in the progression of non-Hodgkin's lymphomas...
  16. ncbi 18F-Fluoro-deoxy-glucose positron emission tomography in lymphoma of mucosa-associated lymphoid tissue: histology makes the difference
    M Hoffmann
    Department of Nuclear Medicine, Medical University Vienna, Vienna, Austria
    Ann Oncol 17:1761-5. 2006
    ..We have evaluated whether the histological feature of plasmacytic differentiation (PD) might explain the heterogeneous behavior of MALT lymphoma regarding 18F-FDG uptake...
  17. doi Somatostatin receptor scintigraphy in primary cutaneous T- and B-cell lymphomas
    J Valencak
    Department of Dermatology, Medical University of Vienna, Vienna, Austria
    J Eur Acad Dermatol Venereol 24:13-7. 2010
    ..Monitoring and repeated staging is of substantial importance in many patients with primary cutaneous T-cell lymphomas (CTCL). For primary cutaneous B-cell lymphomas (CBCL), extensive initial staging is the mainstay for correct diagnosis...
  18. ncbi Early cancer of the stomach arising after successful treatment of gastric MALT lymphoma in patients with autoimmune disease
    M Raderer
    Dept of Internal Medicine I, Division of Oncology, University of Vienna, Austria
    Scand J Gastroenterol 38:294-7. 2003
    ....
  19. ncbi Mutations in apoptosis genes: a pathogenetic factor for human disease
    L Mullauer
    Institute of Clinical Pathology, University of Vienna, Wahringer Gurtel 18 20, A 1090, Vienna, Austria
    Mutat Res 488:211-31. 2001
    ....
  20. ncbi Novel t(5;9)(q33;q22) fuses ITK to SYK in unspecified peripheral T-cell lymphoma
    B Streubel
    Department of Pathology, Medical University of Vienna, Vienna, Austria
    Leukemia 20:313-8. 2006
    ..These results demonstrate the presence of a recurrent t(5;9)(q33;q22) in a subset of unspecified PTCL, which may represent a novel distinct subgroup of PTCL...
  21. pmc Somatostatin-receptor scintigraphy for staging and follow-up of patients with extraintestinal marginal zone B-cell lymphoma of the mucosa associated lymphoid tissue (MALT)-type
    M Raderer
    Department of Internal Medicine I, University of Vienna, Austria
    Br J Cancer 85:1462-6. 2001
    ....
  22. ncbi Templated nucleotide addition and immunoglobulin JH-gene utilization in t(11;14) junctions: implications for the mechanism of translocation and the origin of mantle cell lymphoma
    N Welzel
    Department of Internal Medicine, University of Vienna, Austria
    Cancer Res 61:1629-36. 2001
    ..This is in agreement with the pregerminal center B-cell origin of MCL...
  23. ncbi T(3;14)(p14.1;q32) involving IGH and FOXP1 is a novel recurrent chromosomal aberration in MALT lymphoma
    B Streubel
    Department of Pathology, Vienna General Hospital, Medical University of Vienna, Vienna, Austria
    Leukemia 19:652-8. 2005
    ..1;q32) or trisomy 3. This study identifies FOXP1 as a new translocation partner of IGH in a site-dependent subset of MALT lymphomas...
  24. ncbi Prognostic significance of molecular staging by PCR-amplification of immunoglobulin gene rearrangements in diffuse large B-cell lymphoma (DLBCL)
    G Mitterbauer-Hohendanner
    Clinical Institute of Medical and Chemical Laboratory Diagnostics, Division of Molecular Diagnostics, University of Vienna, Medical School, Wahringer Gurtel, Vienna, Austria
    Leukemia 18:1102-7. 2004
    ....
  25. ncbi 'Blind' antibiotic treatment targeting Chlamydia is not effective in patients with MALT lymphoma of the ocular adnexa
    B Grunberger
    Departments of Medicine I, Division of Oncology, Opththalmology, and Pathology Medical University Vienna, Vienna, Austria
    Ann Oncol 17:484-7. 2006
    ..We present our experience with ex-juvantibus antibiotic treatment in patients diagnosed with MALT lymphoma of the ocular adnexa...
  26. ncbi Treatment of extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue (MALT lymphoma) with mitoxantrone, chlorambucil and prednisone (MCP)
    S Wohrer
    Department of Internal Medicine I, Division of Oncology, University of Vienna, Vienna, Austria
    Ann Oncol 14:1758-61. 2003
    ..This has prompted us to retrospectively analyse our experience with the MCP regimen (mitoxantrone, chlorambucil and prednisone) in patients with MALT lymphoma...
  27. pmc Endoscopic ultrasound in the follow up and response assessment of patients with primary gastric lymphoma
    A Puspok
    Division of Gastroenterology and Hepatology, Department of Internal Medicine IV, AKH, University of Vienna, Vienna, Austria
    Gut 51:691-4. 2002
    ..Its role in the follow up of patients with gastric lymphoma following organ conserving strategies has not been established. Aim: To compare endosonographic response assessment with results of histological evaluation...
  28. ncbi Peripheral T cell lymphoma presenting primarily as lethal midline granuloma
    A Chott
    Department of Pathology, University of Vienna, School of Medicine, Austria
    Hum Pathol 19:1093-101. 1988
    ..The size of the atypical lymphoid cells may be of prognostic significance since the large cell compartment seems to represent the major growth fraction in these PTLs...
  29. ncbi Beta-2-microglobulin levels in patients with extranodal B-cell lymphoma of the mucosa-associated lymphoid tissue (MALT)-type: a retrospective analysis
    M Z Penz
    Department of Internal Medicine I, University of Vienna, Austria
    Anticancer Res 21:3049-52. 2001
    ..While we cannot rule out that B2M might be different in patients with stage I/II disease as compared to more advanced disease, further investigations are necessary to determine the role of this marker in patients with MALT-type lymphoma...
  30. ncbi Hematopoietic donor chimerism and graft-versus-myeloma effect in relapse of multiple myeloma after allogeneic bone marrow transplantation
    F Keil
    Department of Medicine 1, Bone Marrow Transplantation Unit, University of Vienna, Austria
    Ann Hematol 78:376-9. 1999
    ..Both patients were treated with infusions of donor leukocytes from their original donor. Neither patient suffered myelosuppression, and one achieved a stable complete remission...
  31. ncbi CD5 expression in a lymphoma of the mucosa-associated lymphoid tissue (MALT)-type as a marker for early dissemination and aggressive clinical behaviour
    C Wenzel
    Department of Radiation Oncology, University of Vienna, Austria
    Leuk Lymphoma 42:823-9. 2001
    ..Our case lends further support to the notion that CD5+ MALT-lymphomas arising in the head-and-neck area and/or the ocular adnexa might be characterised by an aggressive clinical course...
  32. doi Methotrexate-induced primary cutaneous diffuse large B-cell lymphoma with an 'angiocentric' histological morphology
    K Pfistershammer
    Department of Dermatology, Division of Immunology, Allergy and Infectious Diseases, Medical University of Vienna, Vienna, Austria
    Clin Exp Dermatol 35:59-62. 2010
    ..Thus, this patient was classified as having a rare form of an EBV-negative primary cutaneous T-cell-rich B-cell lymphoma in association with methotrexate treatment...
  33. pmc Chromosomal imbalances in primary and metastatic pancreatic carcinoma as detected by interphase cytogenetics: basic findings and clinical aspects
    N Zojer
    First Department of Internal Medicine, University of Vienna, Austria
    Br J Cancer 77:1337-42. 1998
    ..Two-colour FISH in combination with extensive screening (>10,000 nuclei) seems to be a useful tool to unequivocally identify micrometastatic cells by demonstrating hyperdiploidy and intranuclear chromosomal heterogeneity...
  34. ncbi High expression of lipoprotein lipase in poor risk B-cell chronic lymphocytic leukemia
    D Heintel
    Department of Internal Medicine I, Division of Hematology and Hemostaseology, Medical University of Vienna, Vienna, Austria
    Leukemia 19:1216-23. 2005
    ..001) and a trend for a shorter median overall survival (105 months vs not reached). Our data establish LPL as a prognostic marker and suggest functional consequences of LPL overexpression in patients with B-CLL...
  35. doi Detection of gastric MALT lymphoma spreading to the small bowel by enteroscopy
    W Dolak
    Department of Gastroenterology and Hepatology, Medical University of Vienna, Vienna, Austria
    Endoscopy 43:731-3. 2011
    ..Further studies may quantify the additional diagnostic yield provided by this easy and safe endoscopic method...
  36. ncbi Cutaneous dendritic cells are main targets in acute HIV-1-infection
    I Simonitsch
    Institute of Clinical Pathology, University of Vienna Medical School, Austria
    Mod Pathol 13:1232-7. 2000
    ..Our findings emphasize the critical role of dendritic cells as a virus reservoir and the skin as a major site of HIV replication during the course of the disease...
  37. ncbi Variable frequencies of MALT lymphoma-associated genetic aberrations in MALT lymphomas of different sites
    B Streubel
    Institute of Pathology, Vienna General Hospital, Medical University of Vienna, Vienna, Austria
    Leukemia 18:1722-6. 2004
    ..Our results demonstrate that the three translocations and trisomies 3 and 18 occur at markedly variable frequencies in MALT lymphoma of different sites...
  38. pmc Update on extranodal lymphomas. Conclusions of the Workshop held by the EAHP and the SH in Thessaloniki, Greece
    E Campo
    Department of Pathology, Vienna General Hospital, Medical University of Vienna, Vienna, Austria
    Histopathology 48:481-504. 2006
    ....
  39. ncbi Platelet-derived growth factor-alpha receptor expression supports the growth of conventional chondrosarcoma and is associated with adverse outcome
    I Sulzbacher
    Department of Clinical Pathology, University of Vienna Medical School, Vienna, Austria
    Am J Surg Pathol 25:1520-7. 2001
    ..0172, log-rank test). Because PDGF-alpha receptor expression positively correlates with the aggressiveness of chondrosarcoma, it may be considered as a possible target for novel therapeutic strategies...
  40. pmc 18F-fluoro-deoxy-glucose positron emission tomography (18F-FDG-PET) for assessment of enteropathy-type T cell lymphoma
    M Hoffmann
    Department of Nuclear Medicine, Internal Medicine IV, University of Vienna, Vienna, Austria
    Gut 52:347-51. 2003
    ....
  41. ncbi Effect of intradermal tumor necrosis factor-alpha-induced inflammation on coagulation factors in dermal vessel endothelium. An in vivo study of human skin biopsies
    W Speiser
    Department of Clinical Pharmacology, and Clinical Institute of Medical and Chemical Laboratory Diagnostics, University of Vienna, Austria
    Thromb Haemost 85:362-7. 2001
    ..This procoagulant shift in the haemostatic balance on the cell surface, caused by TNF-alpha-induced inflammation, is likely to contribute to thrombosis associated with tissue inflammation in humans...
  42. doi Mechanisms underlying acquired von Willebrand syndrome associated with an IgM paraprotein
    M Mayerhofer
    Clinical Institute of Medical and Chemical Laboratory Diagnostics, Medical University of Vienna, Vienna, Austria
    Eur J Clin Invest 39:833-6. 2009
    ..The patient required surgery and was successfully managed by chemotherapy consisting of rituximab and fludarabin as well as plasma exchange...
  43. ncbi Expression of mast cell tryptase by myeloblasts in a group of patients with acute myeloid leukemia
    W R Sperr
    Department of Internal Medicine I, Division of Hematology and Hemostaseology, University of Vienna, Austria
    Blood 98:2200-9. 2001
    ..Blast cell persistence or regrowth was associated with a persistently elevated level or recurrent increase of tryptase. Together, tryptase is expressed in myeloblasts in a group of AML and may serve as a useful disease-related marker...
  44. ncbi Chemotherapy for management of localised high-grade gastric B-cell lymphoma: how much is necessary?
    M Raderer
    Department of Internal Medicine I, University of Vienna, Austria
    Ann Oncol 13:1094-8. 2002
    ..We have reported that the large majority of patients achieve complete remission (CR) following three cycles of treatment, and now provide an updated series with special emphasis on patients receiving only short-term chemotherapy...
  45. ncbi Alternative end-joining in follicular lymphomas' t(14;18) translocation
    R Marculescu
    Department of Internal Medicine I, Division of Hematology, University of Vienna, Vienna, Austria
    Leukemia 16:120-6. 2002
    ..This unusual and restricted window of differentiation opens intriguing questions concerning the etiology of the translocation...
  46. ncbi Marginal zone lymphoma of the lacrimal gland spreading to the lung and the bone marrow 11 years after first symptoms
    Annette Zimpfer
    Institute of Pathology, University of Basel, Basel, Switzerland
    Virchows Arch 448:361-5. 2006
    ..The elaboration of this case emphasizes the importance of the combined use of modern diagnostic methods for establishment of correct diagnosis of MALT lymphomas at late relapses, which is essential for proper patient management...
  47. doi Prognostic value of T-cell receptor gamma rearrangement in peripheral blood or bone marrow of patients with peripheral T-cell lymphomas
    Christian Schützinger
    Department of Internal Medicine I, Division of Hematology and Hemostaseology, Medical University of Vienna, A 1090 Vienna, Austria
    Leuk Lymphoma 49:237-46. 2008
    ..Molecular staging in PB and BM by TCR gamma PCR at diagnosis may serve as a useful prognostic tool in PTCL...
  48. pmc CD56-positive haematological neoplasms of the skin: a multicentre study of the Cutaneous Lymphoma Project Group of the European Organisation for Research and Treatment of Cancer
    Chalid Assaf
    Department of Dermatology, Charite, Berlin, Germany
    J Clin Pathol 60:981-9. 2007
    ..However, prognostic subsets within the CD56+ group have been difficult to identify due to the lack of uniform clinicopathological and immunophenotypical criteria...
  49. ncbi Bone marrow microvessel density and its prognostic significance in AML
    Werner Rabitsch
    Department of Internal Medicine I, Vienna, Austria
    Leuk Lymphoma 45:1369-73. 2004
    ..05). Together, our data suggest that the BM-MVD could be a prognostic parameter concerning survival in patients with AML undergoing allogeneic BMT...
  50. ncbi Primary gastric mantle cell lymphoma in a patient with long standing history of Crohn's disease
    Markus Raderer
    Departments of Internal Medicine 1, Internal Medicine IV, University of Vienna, Vienna, Austria
    Leuk Lymphoma 45:1459-62. 2004
    ..This is the first case of a primary localized gastric MCL. The lack of CD5 expression underscores the importance of performing thorough immunohistochemical studies, particularly to exclude MALT lymphoma...
  51. ncbi Reverse transcription-PCR for t(11;18)(q21;q21) staging and monitoring in mucosa-associated lymphoid tissue lymphoma
    Berthold Streubel
    Department of Pathology, Division of Oncology, Department of Internal Medicine I, Vienna General Hospital, Medical University of Vienna, Vienna, Austria
    Clin Cancer Res 12:6023-8. 2006
    ..We have analyzed the use of reverse transcription-PCR (RT-PCR) for the detection of t(11;18)(q21;q21) in histologically infiltrated and normal biopsies at diagnosis and during follow-up to determine its clinical and prognostic effect...
  52. ncbi Monoclonal immunoglobulin production is a frequent event in patients with mucosa-associated lymphoid tissue lymphoma
    Stefan Wohrer
    Department of Medicine I, Division of Oncology, Medical University, Vienna, Austria
    Clin Cancer Res 10:7179-81. 2004
    ..The objective of the present study was to evaluate the incidence and clinical relevance of paraprotein (PP) production in patients with MALT lymphoma...
  53. ncbi Activity of rituximab plus cyclophosphamide, doxorubicin/mitoxantrone, vincristine and prednisone in patients with relapsed MALT lymphoma
    Markus Raderer
    Department of Internal Medicine I, University of Vienna, Vienna, Austria
    Oncology 70:411-7. 2006
    ..As no data on this topic exist for MALT lymphoma, we have retrospectively analysed our experience with R plus cyclophosphamide, doxorubicin/mitoxantrone, vincristine and prednisone (R-CHOP/R-CNOP) in patients with relapsed MALT lymphoma...
  54. doi Indolent systemic mastocytosis associated with atypical small lymphocytic lymphoma: a rare form of concomitant lymphoproliferative disease
    Alexander W Hauswirth
    Department of Internal Medicine I, Division of Hematology and Hemostaseology, Medical University of Vienna, 1090 Vienna, Austria
    Hum Pathol 39:917-24. 2008
    ..The KIT mutation D816V was detected in sorted CD34(+) cells and unfractionated marrow cells but not in CD5(+) SLL cells, confirming the coexistence of 2 distinct neoplasms...
  55. ncbi Transformation of MALT lymphoma to pure plasma cell histology following treatment with the anti-CD20 antibody rituximab
    Stefan Woehrer
    Division of Oncology, Department of Internal Medicine I, Medical University Vienna, Vienna, Austria
    Leuk Lymphoma 46:1645-9. 2005
    ..In addition, our findings suggest that MALT lymphomas with plasmacytic differentiation might have a different 18F-FDG uptake as compared to classical MALT lymphoma...
  56. ncbi MALT lymphoma with t(14;18)(q32;q21)/IGH-MALT1 is characterized by strong cytoplasmic MALT1 and BCL10 expression
    Hongtao Ye
    Department of Pathology, University of Cambridge, Cambridge, UK
    J Pathol 205:293-301. 2005
    ..These results show that MALT1 expression pattern is identical to that of BCL10 in normal lymphoid tissues but varies in MALT lymphomas, with high cytoplasmic expression of both MALT1 and BCL10 characterizing those with t(14;18)(q32;q21)...
  57. ncbi Expression of the granzyme B inhibitor, protease inhibitor 9, by tumor cells in patients with non-Hodgkin and Hodgkin lymphoma: a novel protective mechanism for tumor cells to circumvent the immune system?
    Bellinda A Bladergroen
    Department of Pathology, Free University Medical Center, Amsterdam, The Netherlands
    Blood 99:232-7. 2002
    ..Expression of this inhibitor is yet another mechanism used by tumor cells to escape their elimination by cytotoxic lymphocytes...
  58. ncbi Mutual exclusion of t(11;18)(q21;q21) and numerical chromosomal aberrations in the development of different types of primary gastric lymphomas
    Max I Schreuder
    Department of Pathology, University Medical Centre Nijmegen, Nijmegen, The Netherlands
    Br J Haematol 123:590-9. 2003
    ....
  59. ncbi Expression of osteopontin and vascular endothelial growth factor in benign and malignant bone tumors
    Irene Sulzbacher
    Clinical Institute of Pathology, University of Vienna Medical School, Waehringer Guertel 18 20, 1090 Vienna, Austria
    Virchows Arch 441:345-9. 2002
    ..Although OPN expression correlates with VEGF expression in osteosarcomas, OPN expression does not provide predictive information about the outcome of osteosarcoma patients...
  60. ncbi Immunohistochemical detection of VEGF in the bone marrow of patients with acute myeloid leukemia. Correlation between VEGF expression and the FAB category
    Minoo Ghannadan
    Department of Internal Medicine I, Division of Hematology and Hemostaseology, University of Vienna, Vienna, Austria
    Am J Clin Pathol 119:663-71. 2003
    ..In summary, VEGF expression in the bone marrow is restricted to certain stages of differentiation and maturation of myeloid cells and correlates with the FAB category...
  61. ncbi 18F-fluorodeoxyglucose positron emission tomography (18F-FDG-PET) for staging and follow-up of marginal zone B-cell lymphoma
    Martha Hoffmann
    Department of Nuclear Medicine, University of Vienna, Vienna, Austria
    Oncology 64:336-40. 2003
    ..We have therefore retrospectively evaluated all patients diagnosed with nodal or extranodal MZL who have been referred to our unit for imaging using (18)F-fluorodeoxyglucose positron emission tomography ((18)F-FDG-PET)...
  62. ncbi Extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue of the head and neck area: high rate of disease recurrence following local therapy
    Catharina Wenzel
    Department of Internal Medicine I Division of Oncology, University of Vienna, Vienna, Austria
    Cancer 97:2236-41. 2003
    ..The authors focused on patients' disease localization, initial treatment, clinical course, and follow-up...
  63. ncbi Cytotoxic/natural killer cell cutaneous lymphomas. Report of EORTC Cutaneous Lymphoma Task Force Workshop
    Marco Santucci
    Department of Human Pathology and Oncology, University of Florence Medical School, Florence, Italy
    Cancer 97:610-27. 2003
    ....
  64. ncbi Expression of platelet-derived growth factor-AA is associated with tumor progression in osteosarcoma
    Irene Sulzbacher
    Clinical Institute of Pathology, University of Vienna Medical School, Vienna, Austria
    Mod Pathol 16:66-71. 2003
    ..021, Cox regression). Immunohistochemical analysis of platelet-derived growth factor-AA expression in osteosarcoma may be a useful marker of prognosis and may be considered as a possible target for novel therapeutic strategies...
  65. ncbi High incidence of t(11;18)(q21;q21) in Helicobacter pylori-negative gastric MALT lymphoma
    Hongtao Ye
    Department of Histopathology, University College London, United Kingdom
    Blood 101:2547-50. 2003
    ..Translocation-positive gastric MALT lymphomas tend to be aggressive, and patients with such lymphomas might benefit from prompt treatment and close follow-up...
  66. pmc Chromosomal gains at 9q characterize enteropathy-type T-cell lymphoma
    Andreas Zettl
    Department of Pathology, University of Wurzburg, Germany
    Am J Pathol 161:1635-45. 2002
    ....
  67. ncbi Treatment of extranodal marginal zone B-cell lymphoma of mucosa-associated lymphoid tissue type with cladribine: a phase II study
    Gerald Jäger
    Division of Hematology, Division of Gastroenterology, Institute of Medical Informatics, Statistics and Documentation, Karl Franzens University of Graz, Graz, Austria
    J Clin Oncol 20:3872-7. 2002
    ....
  68. ncbi Stem cell factor-induced bone marrow mast cell hyperplasia mimicking systemic mastocytosis (SM): histopathologic and morphologic evaluation with special reference to recently established SM-criteria
    John Hendrik Jordan
    Department of Internal Medicine 1, University of Vienna, Wahringer Gurtel, Austria
    Leuk Lymphoma 43:575-82. 2002
    ..Based on our case and similar cases mimicking mastocytosis, it seems of importance to apply recently established SM criteria in order to discriminate between reactive MC hyperplasia and true mastocytosis with certainty...
  69. pmc Increased angiogenesis in the bone marrow of patients with systemic mastocytosis
    Friedrich Wimazal
    Department of Internal Medicine I, Division of Hematology and Hemostaseology, University of Vienna, Vienna, Austria
    Am J Pathol 160:1639-45. 2002
    ..The notion that SM is associated with increased BM angiogenesis and vascular endothelial growth factor expression may have implications for the biology of disease and development of new treatment strategies...
  70. ncbi Differential diagnosis of cutaneous infiltrates of B lymphocytes with follicular growth pattern
    Bernd Leinweber
    Department of Dermatology, University of Graz, Austria
    Am J Dermatopathol 26:4-13. 2004
    ..Diagnosis of cutaneous infiltrates of B lymphocytes with follicular growth pattern should be achieved by integration of clinical data with histopathologic, immunohistochemical, and molecular features of the lesions...
  71. pmc FAS (CD95) mutations are rare in gastric MALT lymphoma but occur more frequently in primary gastric diffuse large B-cell lymphoma
    Sabine Wohlfart
    Department of Pathology, University of Vienna, General Hospital Vienna, Vienna, Austria
    Am J Pathol 164:1081-9. 2004
    ..6%) but occur in a subset of primary gastric DLBCL (14.3%) and suggest that these mutations contribute to the pathogenesis of gastric lymphomas by rendering lymphocytes resistant to apoptosis...
  72. ncbi 18F-fluorodeoxyglucose positron emission tomography (18F-FDG-PET) does not visualize follicular lymphoma of the duodenum
    Martha Hoffmann
    Department of Nuclear Medicine, University of Vienna, Vienna, Austria
    Ann Hematol 83:276-8. 2004
    ..18F-FDG-PET findings were not influenced by histological grade or proliferative activity of FL. These findings suggest that 18F-FDG-PET is not useful for clinical assessment of primary duodenal FL...
  73. ncbi Concomitant occurrence of MALT lymphoma and multiple myeloma
    Stefan Wohrer
    Clinical Division of Oncology, Department of Medicine I, University Hospital Vienna, Wahringer Gurtel 18 20, 1090 Vienna, Austria
    Ann Hematol 83:600-3. 2004
    ..This paper describes the diagnostic approach to this particular case and presents immunophenotypic and molecular cytogenetic data suggesting that the two B-cell malignancies were clonally unrelated...
  74. ncbi Frequency of chromosomal aberrations involving MALT1 in mucosa-associated lymphoid tissue lymphoma in patients with Sjögren's syndrome
    Berthold Streubel
    Department of Pathology and Internal Medicine I, Vienna General Hospital, University of Vienna, Vienna, Austria
    Clin Cancer Res 10:476-80. 2004
    ..In view of the association between SS and the development of MALT lymphoma, we have analyzed the frequency of t(11;18)(q21;q21) and t(14;18)(q32;q21) in patients with MALT lymphomas arising in the background of SS...
  75. ncbi Translocation t(11;18)(q21;q21) is not predictive of response to chemotherapy with 2CdA in patients with gastric MALT lymphoma
    Berthold Streubel
    Department of Pathology, University of Vienna, Austria
    Oncology 66:476-80. 2004
    ..We have therefore performed a retrospective analysis of t(11;18)(q21;q21) in patients undergoing chemotherapy with the nucleoside analogue cladribine (2CdA) for gastric MALT lymphoma...
  76. ncbi Antitumor activity of rituximab plus thalidomide in patients with relapsed/refractory mantle cell lymphoma
    Hannes Kaufmann
    University Hospital Vienna, Department of Medicine I, Clinical Division of Oncology, Waehringer Guertel 18 20, A 1090 Vienna, Austria
    Blood 104:2269-71. 2004
    ..Our results suggest that rituximab plus thalidomide has marked antitumor activity in relapsed/refractory MCL and a low toxicity profile, which warrants further evaluation in MCL...
  77. ncbi Severe malabsorption due to refractory celiac disease complicated by extensive gastric heterotopia of the jejunum
    Barbara Tribl
    Department of Internal Medicine IV, Vienna General Hospital, Vienna, Austria
    Am J Surg Pathol 28:262-5. 2004
    ..To the best of our knowledge, this is the first case of refractory celiac disease complicated by extensive jejunal gastric heterotopia, which might have contributed to the severe malabsorption...
  78. ncbi Second complete remission of Helicobacter pylori negative gastric MALT lymphoma following antibiotic treatment
    Marlene Troch
    Leuk Lymphoma 48:204-6. 2007
  79. ncbi Lymphoma-specific genetic aberrations in microvascular endothelial cells in B-cell lymphomas
    Berthold Streubel
    Institutes of Pathology, Center of Excellence in Clinical and Experimental Oncology, Lymphoma Program, Medical University of Vienna, Vienna General Hospital, Vienna
    N Engl J Med 351:250-9. 2004
    ..The growth of most tumors depends on the formation of new blood vessels. In contrast to genetically unstable tumor cells, the endothelial cells of tumor vessels are considered to be normal diploid cells that do not acquire mutations...
  80. ncbi Overexpression of the paternally expressed gene 10 (PEG10) from the imprinted locus on chromosome 7q21 in high-risk B-cell chronic lymphocytic leukemia
    Birgit Kainz
    Division of Hematology and Hemostaseology, Department of Internal Medicine I, Medical University of Vienna, Vienna, Austria
    Int J Cancer 121:1984-93. 2007
    ..Altogether, PEG10 represents a novel marker in B-CLL...
  81. doi Autoimmune lymphoproliferative syndrome (ALPS) caused by Fas (CD95) mutation mimicking sarcoidosis
    Leonhard Müllauer
    Institute of Pathology, Medical University Vienna, Vienna, Austria
    Am J Surg Pathol 32:329-34. 2008
    ..This sarcoidosislike histologic picture extends the spectrum of histiocytic lymph node alterations observed in ALPS and alerts of a potential diagnostic pitfall...
  82. pmc Genomic profiling of peripheral T-cell lymphoma, unspecified, and anaplastic large T-cell lymphoma delineates novel recurrent chromosomal alterations
    Andreas Zettl
    Department of Pathology, University of Wurzburg, Wurzburg, Germany
    Am J Pathol 164:1837-48. 2004
    ..The genetics of PTCL NOS and ALK-negative ALCL differ from other T-NHLs characterized genetically so far, among them enteropathy-type T-cell lymphoma, T-cell prolymphocytic leukemia, and adult T-cell lymphoma/leukemia...
  83. ncbi T(14;18)(q32;q21) involving IGH and MALT1 is a frequent chromosomal aberration in MALT lymphoma
    Berthold Streubel
    Department of Pathology, Division of Oncology, Vienna General Hospital, University of Vienna, Vienna, Austria
    Blood 101:2335-9. 2003
    ..In contrast to t(11;18)(q21;q21)(+) MALT lymphomas, those with t(14;18)(q32;q21) may harbor additional genetic abnormalities...
  84. doi Autoimmune thrombocytopenia in non-Hodgkin's lymphomas
    Alexander W Hauswirth
    Department of Medicine I, Division of Haematology and Haemostaseology, Medical University of Vienna, Vienna, Austria
    Haematologica 93:447-50. 2008
    ..Splenectomy is effective in splenic marginal zone lymphoma. Autoimmune thrombocytopenia in patients with non-Hodgkin's lymphomas is potentially life-threatening and difficult to treat...
  85. ncbi High frequency of genetic aberrations in enteropathy-type T-cell lymphoma
    Anne K Baumgärtner
    Institute of Pathology, Wurzburg University, Wurzburg, Germany
    Lab Invest 83:1509-16. 2003
    ..They showed a different pattern and fewer allelic imbalances (no 3q27, 4q28, 13q14, fewer 5q21, or 5q33.3-34 aberrations) and a lower frequency of MSI than pleomorphic ETLs...
  86. ncbi Comparison of spiral-computed tomography with water-filling of the stomach and endosonography for gastric lymphoma of mucosa-associated lymphoid tissue-type
    Friedrich Vorbeck
    Department of Radiology, Internal Medicine, University of Vienna, Austria
    Digestion 65:196-9. 2002
    ....
  87. ncbi Low p27Kip1 expression is an independent adverse prognostic factor in patients with multiple myeloma
    Martin Filipits
    Department of Medicine I, Clinical Division of Oncology, University of Vienna, A 1090 Vienna, Austria
    Clin Cancer Res 9:820-6. 2003
    ....
  88. ncbi High relapse rate in patients with MALT lymphoma warrants lifelong follow-up
    Markus Raderer
    Clinical Division of Oncology, Departments of Medicine I, Pathology, Medicine IV, and Otorhinolaryngology, Medical University Vienna, Austria
    Clin Cancer Res 11:3349-52. 2005
    ..Little, however, is known about the rate and pattern of relapse following successful treatment...
  89. ncbi Primary cutaneous large B-cell lymphomas: clinicopathologic features, classification, and prognostic factors in a large series of patients
    Kazuo Kodama
    Department of Dermatology, Medical University of Graz, Graz, Austria
    Blood 106:2491-7. 2005
    ..The definition of a third category of LBCLO requires further studies to clarify whether these cases indeed show distinct clinicopathologic features...
  90. ncbi Interaction between synovial inflammatory tissue and bone marrow in rheumatoid arthritis
    Esther Jimenez-Boj
    Division of Rheumatology, Department of Internal Medicine III, Medical University of Vienna, Austria
    J Immunol 175:2579-88. 2005
    ..This suggests that bone marrow is an additional compartment in the disease process of RA...
  91. ncbi Very good partial response in a patient with MALT-lymphoma of the lung after treatment with low-dose thalidomide
    Mathias Kees
    Department of Internal Medicine I, Division of Haematology and Blood Coagulation, Medical University Vienna, Vienna, Austria
    Leuk Lymphoma 46:1379-82. 2005
    ..After 10 months of treatment with low dose thalidomide (100mg/d), very good partial response of the intrapulmonary lesions was achieved...
  92. ncbi Extramedullary plasmacytoma of the adenoids
    Georg Mann
    St Anna Children s Hospital, Vienna, Austria
    Pediatr Blood Cancer 48:361-2. 2007
    ..Surgical treatment without anti-neoplastic therapy in pediatric plasma cell dyscrasias of the pharyngeal lymphoid tissue may be a sufficient curative therapy...
  93. ncbi Rituximab for treatment of advanced extranodal marginal zone B cell lymphoma of the mucosa-associated lymphoid tissue lymphoma
    Markus Raderer
    Department of Internal Medicine I, Division of Oncology and Internal Medicine IV, University of Vienna, Vienna, Austria
    Oncology 65:306-10. 2003
    ..Owing to its B cell lineage, it appears to be a potential target for treatment with the CD20 antibody rituximab. We present an analysis of our experience with rituximab for treatment of patients with advanced MALT lymphoma...
  94. ncbi Amplification of NOTCH1 and ABL1 gene loci is a frequent aberration in enteropathy-type T-cell lymphoma
    Pavlina Cejkova
    Department of Pathology and Laboratory Medicine, Roswell Park Cancer Institute, Elm and Carlton Streets, Buffalo, NY, 14263, USA
    Virchows Arch 446:416-20. 2005
    ..From 9q34 known genes, NOTCH1 could thus be the primary target of genomic DNA amplification in ETL...
  95. ncbi Subcutaneous, blastic natural killer (NK), NK/T-cell, and other cytotoxic lymphomas of the skin: a morphologic, immunophenotypic, and molecular study of 50 patients
    Cesare Massone
    Department of Dermatology, University of Graz, Austria
    Am J Surg Pathol 28:719-35. 2004
    ..With the exception of SPTCL, analysis of follow-up data from our patients showed that these groups of lymphomas are characterized by an aggressive course, regardless of the diagnostic category...
  96. ncbi Antibiotic treatment is not effective in patients infected with Helicobacter pylori suffering from extragastric MALT lymphoma
    Birgit Grünberger
    Department of Medicine I, Medical University Vienna, Vienna, Austria
    J Clin Oncol 24:1370-5. 2006
    ..Apart from anecdotal reports implicating Helicobacter pylori (HP) in the development of extragastric mucosa associated lymphoid tissue (MALT) lymphoma, no large scale prospective studies have been performed on this topic...
  97. ncbi Effective treatment of indolent non-hodgkin's lymphomas with mitoxantrone, chlorambucil and prednisone
    Stefan Wohrer
    Department of Medicine I, Clinical Division of Oncology, University Hospital Vienna, Austria
    Onkologie 28:73-8. 2005
    ..Conclusion: In summary, MCP is an effective and well tolerated chemotherapy regimen and is probably an alternative to the more toxic CHOP regimen, especially in older patients...
  98. ncbi Borrelia burgdorferi-associated lymphocytoma cutis: clinicopathologic, immunophenotypic, and molecular study of 106 cases
    Claudia Colli
    Department of Dermatology, University of Graz, Austria
    J Cutan Pathol 31:232-40. 2004
    ..In summary, B. burgdorferi-associated LC can present with misleading histopathologic, immunophenotypic, and molecular features, and integration of all data is necessary for a correct diagnosis...
  99. ncbi Molecular cytogenetic evidence of t(14;18)(IGH;BCL2) in a substantial proportion of primary cutaneous follicle center lymphomas
    Berthold Streubel
    Department of Pathology, Medical University of Vienna, Vienna General Hospital, Vienna, Austria
    Am J Surg Pathol 30:529-36. 2006
    ..The reason(s) why BCL2 rearrangements escape the detection by PCR is (are) not clear but could be due to BCL2 mutations, breakpoints outside the amplified DNA, or a high load of somatic mutations...
  100. ncbi Assessment of disease dissemination in gastric compared with extragastric mucosa-associated lymphoid tissue lymphoma using extensive staging: a single-center experience
    Markus Raderer
    Department of Internal Medicine I and IV, University of Vienna, Austria
    J Clin Oncol 24:3136-41. 2006
    ..We report our findings with an extensive staging routine applied in patients diagnosed with MALT lymphoma at our institution...
  101. ncbi Genetic aberrations in primary cutaneous large B-cell lymphoma: a fluorescence in situ hybridization study of 25 cases
    Thomas Wiesner
    Department of Dermatology, Medical University Graz, Graz, Austria
    Am J Surg Pathol 29:666-73. 2005
    ....