Michael Breitenbach

Summary

Affiliation: University of Salzburg
Country: Austria

Publications

  1. ncbi request reprint Involvement of oxidative stress response genes in redox homeostasis, the level of reactive oxygen species, and ageing in Saccharomyces cerevisiae
    Tamara Drakulic
    Ramaciotti Centre for Gene Function Analysis and School of Biotechnology and Biomolecular Sciences, University of New South Wales, Kensington, Sydney, Australia
    FEMS Yeast Res 5:1215-28. 2005
  2. doi request reprint Senescence and apoptosis in yeast mother cell-specific aging and in higher cells: a short review
    Peter Laun
    Department of Cell Biology, Division of Genetics, University of Salzburg, Salzburg, Austria
    Biochim Biophys Acta 1783:1328-34. 2008
  3. ncbi request reprint Oxidative stress and neurodegeneration: the yeast model system
    Michael Breitenbach
    Department of Cell Biology, Divison of Genetics, University of Salzburg, 5020 Salzburg, Austria
    Front Biosci (Landmark Ed) 18:1174-93. 2013
  4. pmc Dynamic rerouting of the carbohydrate flux is key to counteracting oxidative stress
    Markus Ralser
    Max Planck Institute for Molecular Genetics, Ihnestrasse 73, 14195 Berlin, Germany
    J Biol 6:10. 2007
  5. pmc Non-random clustering of stress-related genes during evolution of the S. cerevisiae genome
    Debra T Burhans
    Dept of Computer Science and Bioinformatics Program, Canisius College, Buffalo, NY, 14208, USA
    BMC Evol Biol 6:58. 2006
  6. ncbi request reprint The actin cytoskeleton, RAS-cAMP signaling and mitochondrial ROS in yeast apoptosis
    Michael Breitenbach
    University of Salzburg, 5020 Salzburg, Austria
    Trends Cell Biol 15:637-9. 2005
  7. ncbi request reprint Impact of current genome projects on the study of pathogenic and allergenic fungi
    M Breitenbach
    Department of Genetics and General Biology, University of Salzburg, Salzburg, Austria
    Chem Immunol 81:5-9. 2002
  8. doi request reprint The role of mitochondria in the aging processes of yeast
    Michael Breitenbach
    Division of Genetics, Department of Cell Biology, University of Salzburg, Salzburg, Austria
    Subcell Biochem 57:55-78. 2012
  9. doi request reprint Introduction
    Michael Breitenbach
    Division of Genetics, Department of Cell Biology, University of Salzburg, Salzburg, Austria
    Subcell Biochem 57:1-12. 2012
  10. ncbi request reprint The allergens of Cladosporium herbarum and Alternaria alternata
    Michael Breitenbach
    Department of Genetics and General Biology, University of Salzburg, Salzburg, Austria
    Chem Immunol 81:48-72. 2002

Detail Information

Publications61

  1. ncbi request reprint Involvement of oxidative stress response genes in redox homeostasis, the level of reactive oxygen species, and ageing in Saccharomyces cerevisiae
    Tamara Drakulic
    Ramaciotti Centre for Gene Function Analysis and School of Biotechnology and Biomolecular Sciences, University of New South Wales, Kensington, Sydney, Australia
    FEMS Yeast Res 5:1215-28. 2005
    ..Heterogeneity was detected in populations of strains with compromised anti-oxidant defences, and as cells aged they shifted from one cell type with low ROS content to another with much higher intracellular ROS...
  2. doi request reprint Senescence and apoptosis in yeast mother cell-specific aging and in higher cells: a short review
    Peter Laun
    Department of Cell Biology, Division of Genetics, University of Salzburg, Salzburg, Austria
    Biochim Biophys Acta 1783:1328-34. 2008
    ..Studying the current literature, it appears that little is known for sure in this field and our review will therefore be, for a large part, more like a memorandum or a program for future research...
  3. ncbi request reprint Oxidative stress and neurodegeneration: the yeast model system
    Michael Breitenbach
    Department of Cell Biology, Divison of Genetics, University of Salzburg, 5020 Salzburg, Austria
    Front Biosci (Landmark Ed) 18:1174-93. 2013
    ....
  4. pmc Dynamic rerouting of the carbohydrate flux is key to counteracting oxidative stress
    Markus Ralser
    Max Planck Institute for Molecular Genetics, Ihnestrasse 73, 14195 Berlin, Germany
    J Biol 6:10. 2007
    ..Eukaryotic cells have evolved various response mechanisms to counteract the deleterious consequences of oxidative stress. Among these processes, metabolic alterations seem to play an important role...
  5. pmc Non-random clustering of stress-related genes during evolution of the S. cerevisiae genome
    Debra T Burhans
    Dept of Computer Science and Bioinformatics Program, Canisius College, Buffalo, NY, 14208, USA
    BMC Evol Biol 6:58. 2006
    ..Coordinately regulated genes often physically cluster in eukaryotic genomes, for reasons that remain unclear...
  6. ncbi request reprint The actin cytoskeleton, RAS-cAMP signaling and mitochondrial ROS in yeast apoptosis
    Michael Breitenbach
    University of Salzburg, 5020 Salzburg, Austria
    Trends Cell Biol 15:637-9. 2005
    ..This effect can be suppressed by downregulation of the RAS-cAMP signaling pathway, thus establishing the existence of a new and complex regulatory network...
  7. ncbi request reprint Impact of current genome projects on the study of pathogenic and allergenic fungi
    M Breitenbach
    Department of Genetics and General Biology, University of Salzburg, Salzburg, Austria
    Chem Immunol 81:5-9. 2002
  8. doi request reprint The role of mitochondria in the aging processes of yeast
    Michael Breitenbach
    Division of Genetics, Department of Cell Biology, University of Salzburg, Salzburg, Austria
    Subcell Biochem 57:55-78. 2012
    ....
  9. doi request reprint Introduction
    Michael Breitenbach
    Division of Genetics, Department of Cell Biology, University of Salzburg, Salzburg, Austria
    Subcell Biochem 57:1-12. 2012
    ..The purpose of this chapter is to give the newcomer an introduction to the field including some basic technical questions...
  10. ncbi request reprint The allergens of Cladosporium herbarum and Alternaria alternata
    Michael Breitenbach
    Department of Genetics and General Biology, University of Salzburg, Salzburg, Austria
    Chem Immunol 81:48-72. 2002
  11. ncbi request reprint Enolases are highly conserved fungal allergens
    M Breitenbach
    Department of Genetics and General Biology, University of Salzburg, Austria
    Int Arch Allergy Immunol 113:114-7. 1997
    ..We have therefore further analyzed the allergens of the two moulds, Alternaria alternata and Cladosporium herbarum and found that enolases (EC 4.2.1.11) are major allergens, at least of the two fungal species just mentioned...
  12. doi request reprint Quantitation of (a)symmetric inheritance of functional and of oxidatively damaged mitochondrial aconitase in the cell division of old yeast mother cells
    Harald Klinger
    Department of Cell Biology, Division of Genetics, University of Salzburg, Hellbrunnerstrasse 34, Salzburg, Austria
    Exp Gerontol 45:533-42. 2010
    ..As the aconitase remains mitochondrial during aging and cell division, our findings could indicate discrimination between active and no longer active mitochondria during the process...
  13. pmc The mitochondrial ribosomal protein of the large subunit, Afo1p, determines cellular longevity through mitochondrial back-signaling via TOR1
    Gino Heeren
    Department of Cell Biology, Division of Genetics, University of Salzburg, 5020 Salzburg, Austria
    Aging (Albany NY) 1:622-36. 2009
    ..AFO1/MRPL25 function establishes a new connection between mitochondria, metabolism and aging...
  14. pmc Candida albicans AGE3, the ortholog of the S. cerevisiae ARF-GAP-encoding gene GCS1, is required for hyphal growth and drug resistance
    Thomas Lettner
    Department of Cell Biology, University of Salzburg, Salzburg, Austria
    PLoS ONE 5:e11993. 2010
    ..Hyphal growth and multidrug resistance of C. albicans are important features for virulence and antifungal therapy of this pathogenic fungus...
  15. doi request reprint Alternaria alternata TCTP, a novel cross-reactive ascomycete allergen
    Raphaela Rid
    Department of Cell Biology, University of Salzburg, Salzburg, Austria
    Mol Immunol 46:3476-87. 2009
    ..herbarum and human counterparts as determined via Western blotting and in vitro inhibition approaches...
  16. pmc Yno1p/Aim14p, a NADPH-oxidase ortholog, controls extramitochondrial reactive oxygen species generation, apoptosis, and actin cable formation in yeast
    Mark Rinnerthaler
    Department of Cell Biology, Division of Genetics, University of Salzburg, 5020 Salzburg, Austria
    Proc Natl Acad Sci U S A 109:8658-63. 2012
    ..Several independent lines of evidence point to regulation of the actin cytoskeleton by reactive oxygen species (ROS) produced by Yno1p...
  17. doi request reprint H2O2-dependent translocation of TCTP into the nucleus enables its interaction with VDR in human keratinocytes: TCTP as a further module in calcitriol signalling
    Raphaela Rid
    Department of Cell Biology, Division of Genetics, University of Salzburg, Salzburg, Austria
    J Steroid Biochem Mol Biol 118:29-40. 2010
    ....
  18. ncbi request reprint The role of respiration, reactive oxygen species and oxidative stress in mother cell-specific ageing of yeast strains defective in the RAS signalling pathway
    Gino Heeren
    Department of Cell Biology, University of Salzburg, Hellbrunnerstrasse 34, A 5020 Salzburg, Austria
    FEMS Yeast Res 5:157-67. 2004
    ..Our results indicate that oxidative stress resulting from a disturbance of redox balance can play a major role in mother cell-specific lifespan determination of yeast cells...
  19. ncbi request reprint Ribosomal proteins Rpl10 and Rps6 are potent regulators of yeast replicative life span
    Andreas Chiocchetti
    Department of Cell Biology, University of Salzburg, Hellbrunnerstrasse 34, A 5020 Salzburg, Austria
    Exp Gerontol 42:275-86. 2007
    ..Thus, reduction of gene dosage of RP genes belonging to both the 60S and the 40S subunit affect lifespan, possibly altering the aging process by modulation of translation...
  20. ncbi request reprint The spectrum of fungal allergy
    Birgit Simon-Nobbe
    Department of Cell Biology, University of Salzburg, Salzburg, Austria
    Int Arch Allergy Immunol 145:58-86. 2008
    ..This review aims to give an overview of the biology of molds and diseases caused by molds in humans, as well as a detailed summary of the latest results on recombinant fungal allergens...
  21. doi request reprint The vacuolar serine protease, a cross-reactive allergen from Cladosporium herbarum
    Verena Pöll
    Dept of Cell Biology, University of Salzburg, Salzburg, Austria
    Mol Immunol 46:1360-73. 2009
    ..herbarum allergy-diagnosis and -therapy. Moreover, Cla h 9 represents a further member of the subtilisin-like serine protease allergen-family, which stresses the importance of these proteins with respect to fungal IgE-cross-reactivity...
  22. ncbi request reprint MMI1 (YKL056c, TMA19), the yeast orthologue of the translationally controlled tumor protein (TCTP) has apoptotic functions and interacts with both microtubules and mitochondria
    Mark Rinnerthaler
    Department of Cell Biology, Division of Genetics, University of Salzburg, Austria
    Biochim Biophys Acta 1757:631-8. 2006
    ..Our results so far indicate that Mmi1p is one of the few proteins establishing a functional link between microtubules and mitochondria which may be needed for correct localization of mitochondria during cell division...
  23. doi request reprint Isolation and immunological characterization of a novel Cladosporium herbarum allergen structurally homologous to the alpha/beta hydrolase fold superfamily
    Raphaela Rid
    Department of Cell Biology, Division of Genetics, University of Salzburg, Salzburg, Austria
    Mol Immunol 47:1366-77. 2010
    ..herbarum hydrolase could be included in forthcoming minimal testing sets when fungal allergy is suspected...
  24. pmc Yeast mother cell-specific ageing, genetic (in)stability, and the somatic mutation theory of ageing
    Peter Laun
    Department of Cell Biology, Division of Genetics, University of Salzburg, Austria
    Nucleic Acids Res 35:7514-26. 2007
    ..We are reviewing here the evidence for genetic change and its causality in the mother cell-specific ageing process of yeast...
  25. ncbi request reprint Cladosporium herbarum translationally controlled tumor protein (TCTP) is an IgE-binding antigen and is associated with disease severity
    Raphaela Rid
    Department of Cell Biology, Division of Genetics, University of Salzburg, Hellbrunnerstrasse 34, A 5020 Salzburg, Austria
    Mol Immunol 45:406-18. 2008
    ..herbarum TCTP could completely inhibit reactivity with HRF. Furthermore, it appears that patients reactive to TCTP have a higher probability to suffer from asthma than other allergic patients...
  26. ncbi request reprint Alternaria alternata NADP-dependent mannitol dehydrogenase is an important fungal allergen
    P B Schneider
    Division of Genetics, Department of Cell Biology, University of Salzburg, Salzburg, Austria
    Clin Exp Allergy 36:1513-24. 2006
    ..Mannitol dehydrogenase (MtDH) has previously been shown to be a major allergen of Cladosporium herbarum and cross-reactivity has been demonstrated for several fungal allergens...
  27. pmc Mmi1, the yeast homologue of Mammalian TCTP, associates with stress granules in heat-shocked cells and modulates proteasome activity
    Mark Rinnerthaler
    Department Cell Biology, Division Genetics, University of Salzburg, Salzburg, Austria
    PLoS ONE 8:e77791. 2013
    ....
  28. doi request reprint UME6 is a crucial downstream target of other transcriptional regulators of true hyphal development in Candida albicans
    Ute Zeidler
    Department of Cell Biology, University of Salzburg, Hellbrunnerstrasse 34, Salzburg, Austria
    FEMS Yeast Res 9:126-42. 2009
    ..The expression of all hyphae-specific genes investigated depended on UME6 expression. A model for transcriptional regulation of hyphal development and the role of Ume6p is proposed...
  29. ncbi request reprint Yeast as a model for chronological and reproductive aging - a comparison
    Peter Laun
    Department of Cell Biology, Division of Genetics, University of Salzburg, Hellbrunnerstrasse 34, 5020 Salzburg, Austria
    Exp Gerontol 41:1208-12. 2006
  30. ncbi request reprint A comparison of the aging and apoptotic transcriptome of Saccharomyces cerevisiae
    Peter Laun
    Department of Cell Biology, Salzburg University, Hellbrunnerstr 34, Austria
    FEMS Yeast Res 5:1261-72. 2005
    ..These functional classes represent the response of the cell to the known cellular insults, which occur during aging and apoptosis. As we have shown previously, final-stage senescent yeast mother cells (of the wild-type) are apoptotic...
  31. ncbi request reprint NADP-dependent mannitol dehydrogenase, a major allergen of Cladosporium herbarum
    Birgit Simon-Nobbe
    Department of Cell Biology, University of Salzburg, Hellbrunnerstrasse 34, A 5020 Salzburg, Austria
    J Biol Chem 281:16354-60. 2006
    ..This protein therefore is a new major allergen of C. herbarum...
  32. pmc Specialized yeast ribosomes: a customized tool for selective mRNA translation
    Johann W Bauer
    Department of Cell Biology, University of Salzburg, Salzburg, Austria
    PLoS ONE 8:e67609. 2013
    ..Importantly, the RP L35B sub-population of specialized ribosomes leave both translation of a reporter luciferase carrying a different PTC and bulk mRNA translation largely unaltered. ..
  33. ncbi request reprint A novel assay for replicative lifespan in Saccharomyces cerevisiae
    Stefanie Jarolim
    Department of Cell Biology, University of Salzburg, Hellbrunnerstrasse 34, 5020 Salzburg, Austria
    FEMS Yeast Res 5:169-77. 2004
    ..The lifespan-increasing activity of resveratrol is also reproduced. Compared to current assays, this new strategy promises to significantly increase the possible number of replicative-lifespan determinations...
  34. pmc Saccharomyces cerevisiae Genes Involved in Survival of Heat Shock
    Stefanie Jarolim
    Division of Genetics, Department of Cell Biology, University of Salzburg, Salzburg, A 5020 Austria
    G3 (Bethesda) 3:2321-33. 2013
    ..The cell division transcription factor Swi6p and Hac1p involved in the unfolded protein response also play roles in maintenance of heat-shock resistance. ..
  35. doi request reprint Crystal structure of the NADP-dependent mannitol dehydrogenase from Cladosporium herbarum: Implications for oligomerisation and catalysis
    Dorota Nüss
    Division of Structural Biology, Department of Molecular Biology, University of Salzburg, Salzburg, Austria
    Biochimie 92:985-93. 2010
    ..Based on the well defined active site region and a comparative analysis with related structures, we can also clarify the atypical enzymatic properties of MtDH by two alternative binding modes of the substrate to the active site...
  36. ncbi request reprint The IgE antigen receptor: a key regulator for the production of IgE antibodies
    G Achatz
    Institut für Genetik und Allgemeine Biologie, Salzburg, Austria
    Int Arch Allergy Immunol 124:31-4. 2001
    ..We think that the cytoplasmic tail of IgE is involved in a signal transduction which leads to the expression of high quantities and qualities of secreted IgE immunoglobulins...
  37. ncbi request reprint Modulation of IgE reactivity of allergens by site-directed mutagenesis: potential use of hypoallergenic variants for immunotherapy
    F Ferreira
    Institut für Genetik und Allgemeine Biologie, Universitat Salzburg, Austria
    FASEB J 12:231-42. 1998
    ..The approach described here may be generally applied to produce allergen variants to be used in a safe therapy form of immediate-type allergies...
  38. ncbi request reprint Somatic diversity of the immunoglobulin repertoire is controlled in an isotype-specific manner
    E Luger
    Department of Genetics and General Biology, , Salzburg, Austria
    Eur J Immunol 31:2319-30. 2001
    ..Therefore, the composition of the antigen-receptor is responsible for the selection process and the expansion of antigen-specific cells, leading to an isotype-specific antibody repertoire...
  39. ncbi request reprint Identification and phenotypic analysis of two glyoxalase II encoding genes from Saccharomyces cerevisiae, GLO2 and GLO4, and intracellular localization of the corresponding proteins
    A Bito
    Institute for Genetics and General Biology, University of Salzburg, A 5020 Salzburg, Austria
    J Biol Chem 272:21509-19. 1997
    ..However, to get an active Glo4p protein in E. coli, the putative mitochondrial transit peptide at the N-terminal end had to be removed by shortening the 5' end of the GLO4 open reading frame...
  40. ncbi request reprint Heterologous expression, purification, and kinetic comparison of the cytoplasmic and mitochondrial glyoxalase II enzymes, Glo2p and Glo4p, from Saccharomyces cerevisiae
    A Bito
    Department for Genetics and General Biology, University of Salzburg, Salzburg, A 5020, Austria
    Protein Expr Purif 17:456-64. 1999
    ..However, both yeast enzymes showed a severalfold lower preference for the more hydrophobic substrate, S-d-mandeloylglutathione...
  41. ncbi request reprint Functional interaction in establishment of ribosomal integrity between small subunit protein rpS6 and translational regulator rpL10/Grc5p
    Karin Pachler
    Department of Cell Biology, Paris Lodron University Salzburg, Hellbrunnerstrasse 34, A 5020 Salzburg, Austria
    FEMS Yeast Res 5:271-80. 2004
    ....
  42. pmc Superoxide radicals have a protective role during H2O2 stress
    Geoffrey W Thorpe
    Ramaciotti Centre for Gene Function Analysis, School of Biotechnology and Biomolecular Sciences, University of New South Wales, Sydney, NSW 2052, Australia Heart Research Institute, Newtown, NSW 2042, Australia Internal Medicine I, Paracelsus Medical University, 5020 Salzburg, Austria Department of Cell Biology, University of Salzburg, 5020 Salzburg, Austria
    Mol Biol Cell 24:2876-84. 2013
    ..High levels of the superoxide radical are still toxic. These opposing, concentration-dependent roles of the superoxide radical comprise a form of hormesis and show one ROS having a hormetic effect on the toxicity of another...
  43. ncbi request reprint Molecular cloning of major and minor allergens of Alternaria alternata and Cladosporium herbarum
    G Achatz
    Institute of Genetics and General Biology, University of Salzburg, Austria
    Mol Immunol 32:213-27. 1995
    ..One allergen (P2) is a homolog of a very highly conserved human lupus erythematodes (LE) antigen. None of the fungal allergens is clearly related to other known non-fungal allergens...
  44. ncbi request reprint GRC5 and NMD3 function in translational control of gene expression and interact genetically
    T Karl
    Department of Genetics and General Biology, University of Salzburg, Hellbrunnerstrasse 34, A 5020 Salzburg, Austria
    Curr Genet 34:419-29. 1999
    ..NMD3 was previously identified as a component of the nonsense-mediated mRNA decay pathway. The point mutations within NMD3 reported here may define a domain important for the functional interaction of Grc5p and Nmd3p...
  45. doi request reprint Yeast AgingYeast aging and Apoptosisapoptosis
    Peter Laun
    Division of Genetics, Department of Cell Biology, University of Salzburg, Salzburg, Austria
    Subcell Biochem 57:207-32. 2012
    ....
  46. ncbi request reprint Identification of vitamin D target genes in human keratinocytes by subtractive screening
    Pamela Renate Moll
    Department of Genetics and General Biology, University of Salzburg, Hellbrunnerstrasse 34, A 5020 Salzburg, Austria
    J Steroid Biochem Mol Biol 89:261-7. 2004
    ....
  47. pmc The sporulation-specific enzymes encoded by the DIT1 and DIT2 genes catalyze a two-step reaction leading to a soluble LL-dityrosine-containing precursor of the yeast spore wall
    P Briza
    Institut für Genetik und Allgemeine Biologie, University of Salzburg, Austria
    Proc Natl Acad Sci U S A 91:4524-8. 1994
    ..On the basis of these findings we suggest a biosynthetic pathway for the top layer of the yeast spore wall...
  48. pmc Phage display based cloning of proteins interacting with the cytoplasmic tail of membrane immunoglobulins
    Roland Geisberger
    Department of Genetics and General Biology, Hellbrunnerstrasse 34, A 5020 Salzburg, Austria
    Dev Immunol 9:127-34. 2002
    ....
  49. doi request reprint Metabolic changes through hypoxia in humans and in yeast as a comparable cell model
    Nikolaus C Netzer
    Hermann Buhl Institute for Hypoxia and Sleep Medicine Research, Paracelsus Medical University, Salzburg, Austria
    Sleep Breath 14:221-5. 2010
    ..Animal studies with different time dosage regimens of hypoxia in animal cages revealed different and partly confusing results regarding fat metabolism under hypoxia...
  50. ncbi request reprint Functional analysis in yeast of the Brix protein superfamily involved in the biogenesis of ribosomes
    Edith Bogengruber
    Institute of Genetics and General Biology, University of Salzburg, 5020, Salzburg, Austria
    FEMS Yeast Res 3:35-43. 2003
    ..This agrees well with the fact that these three proteins, like Brx1p, are located in the nucleolus. Moreover, all four proteins closely interact functionally, because all four mutants are suppressed by the same multicopy suppressor gene...
  51. ncbi request reprint A DNA vaccine encoding the outer surface protein C from Borrelia burgdorferi is able to induce protective immune responses
    Sandra Scheiblhofer
    Institute of Chemistry and Biochemistry, Immunology Group, University of Salzburg, Hellbrunnerstr 34, 5020 Salzburg, Austria
    Microbes Infect 5:939-46. 2003
    ..burgdorferi organisms per mouse was between 80% and 100% for all groups. These results demonstrate, for the first time, that a DNA vaccine encoding OspC of B. burgdorferi is suitable for inducing protection against Lyme borreliosis...
  52. ncbi request reprint The influence of oxygen toxicity on yeast mother cell-specific aging
    R Nestelbacher
    Institut für Genetik und Allgemeine Biologie, Hellbrunnerstr 34, A 5020, Salzburg, Austria
    Exp Gerontol 35:63-70. 2000
    ..These findings are discussed in the light of recent results relating to oxygen toxicity in the aging process of higher organisms...
  53. ncbi request reprint Aged mother cells of Saccharomyces cerevisiae show markers of oxidative stress and apoptosis
    P Laun
    Department of Genetics, University of Salzburg, Hellbrunnerstr. 34, A-5020 Salzburg, Austria
    Mol Microbiol 39:1166-73. 2001
    ....
  54. ncbi request reprint Partial uncoupling of oxidative phosphorylation induces premature senescence in human fibroblasts and yeast mother cells
    Petra Stöckl
    Institute for Biomedical Aging Research, Austrian Academy of Sciences, Rennweg 10, A 6020 Innsbruck, Austria
    Free Radic Biol Med 43:947-58. 2007
    ....
  55. ncbi request reprint Unfolding and double-stranded DNA binding of the cold shock protein homologue Cla h 8 from Cladosporium herbarum
    S Fabio Falsone
    Department of Protein Chemistry and Biophysics, Institute of Pharmaceutical Chemistry and Pharmaceutical Technology, University of Graz, A 8010 Graz, Austria
    J Biol Chem 277:16512-6. 2002
    ..The enhanced affinity for DNA at low temperatures together with the low unfolding transition refer to the functional significance of Cla h 8 at reduced temperatures...
  56. ncbi request reprint Lipid hydroperoxides activate the mitogen-activated protein kinase Mpk1p in Saccharomyces cerevisiae
    Nazif Alic
    Ramaciotti Centre for Gene Function Analysis, School of Biotechnology and Biomolecular Sciences, University of New South Wales, 2052 New South Wales, Australia
    J Biol Chem 278:41849-55. 2003
    ..Furthermore, it revealed that Mpk1p is required for the regulation of 97 LoaOOH-responsive transcripts. Evidence is presented that the activation of Mpk1p may be caused by the activation of protein kinase C by LoaOOH...
  57. ncbi request reprint Translational regulator RpL10p/Grc5p interacts physically and functionally with Sed1p, a dynamic component of the yeast cell surface
    Kamil Oender
    Department of Genetics and General Biology, Paris Lodron University Salzburg, Hellbrunnerstrasse 34, A 5020 Salzburg
    Yeast 20:281-94. 2003
    ..PLB3 encodes a phospholipase, which is active in the breakdown of membrane lipids. Our results support the view that Grc5p/RpL10p links ribosome function to membrane turnover and cell surface biogenesis...
  58. ncbi request reprint Systematic analysis of sporulation phenotypes in 624 non-lethal homozygous deletion strains of Saccharomyces cerevisiae
    Peter Briza
    Institut für Genetik und Allgemeine Biologie, Universitat Salzburg, Hellbrunnerstrasse 34, A 5020 Salzburg, Austria
    Yeast 19:403-22. 2002
    ..Taken together, about 8% of all single gene deletion mutants of non-essential genes of Saccharomyces cerevisiae seem to display a clear and reproducible sporulation phenotype...
  59. ncbi request reprint Apoptosis, ageing and redox homeostasis in yeasts
    Michael Breitenbach
    FEMS Yeast Res 5:1191-2. 2005
  60. ncbi request reprint Evidence for ORC-dependent repression of budding yeast genes induced by starvation and other stresses
    Lakshmi Ramachandran
    Department of Cell Stress Biology and Roswell Park Cancer Institute, Buffalo, NY 14263, USA
    FEMS Yeast Res 6:763-76. 2006
    ..Our findings suggest a role for ORC in the repression of a large number of budding yeast genes induced by starvation or other aspects of a deleterious environment...
  61. ncbi request reprint Phenotypic analysis of gene deletant strains for sensitivity to oxidative stress
    Vincent J Higgins
    Clive and Vera Ramaciotti Centre for Gene Function Analysis, School of Biochemistry and Molecular Genetics, University of New South Wales, Sydney, NSW 2052, Australia
    Yeast 19:203-14. 2002
    ..Further analysis of these genes may reveal unknown mechanisms protecting the cell against reactive oxygen species...