M R Speicher

Summary

Country: Austria

Publications

  1. pmc Identification of small gains and losses in single cells after whole genome amplification on tiling oligo arrays
    Jochen B Geigl
    Institute of Human Genetics, Medical University of Graz, Harrachgasse 21 8, A 8010 Graz, Austria
    Nucleic Acids Res 37:e105. 2009
  2. pmc Predictive diagnosis of the cancer prone Li-Fraumeni syndrome by accident: new challenges through whole genome array testing
    T Schwarzbraun
    Institute of Human Genetics, Medical University of Graz, Harrachgasse 21 8, A 8010 Graz, Austria
    J Med Genet 46:341-4. 2009
  3. ncbi request reprint Effect of genome-wide association studies, direct-to-consumer genetic testing, and high-speed sequencing technologies on predictive genetic counselling for cancer risk
    Michael R Speicher
    Medical University of Graz, Institute of Human Genetics, Graz, Austria
    Lancet Oncol 11:890-8. 2010

Collaborators

  • Zlatko Trajanoski
  • T Schwarzbraun
  • Jochen B Geigl
  • K Wagner
  • P M Kroisel
  • Eva M Hoffmann
  • Martina Auer
  • U Gruber Sedlmayr
  • Julie Waldispuehl-Geigl
  • Michael A Schenk
  • Lars O Baumbusch
  • A C Obenauf
  • Maria Fischer
  • Martina Hörmann
  • A Langmann
  • Anna C Obenauf

Detail Information

Publications4

  1. pmc Identification of small gains and losses in single cells after whole genome amplification on tiling oligo arrays
    Jochen B Geigl
    Institute of Human Genetics, Medical University of Graz, Harrachgasse 21 8, A 8010 Graz, Austria
    Nucleic Acids Res 37:e105. 2009
    ..Our data suggest that when assessed with sufficiently sensitive methods high-resolution oligo-arrays allow a reliable identification of CNVs as small as 500 kb in cell pools (5 or 10 cells), and of 2.6-3.0 Mb in single cells...
  2. pmc Predictive diagnosis of the cancer prone Li-Fraumeni syndrome by accident: new challenges through whole genome array testing
    T Schwarzbraun
    Institute of Human Genetics, Medical University of Graz, Harrachgasse 21 8, A 8010 Graz, Austria
    J Med Genet 46:341-4. 2009
    ..CONCLUSION: Thus, array CGH resulted in an unintended predictive diagnosis of an increased tumour susceptibility as observed in Li-Fraumeni syndrome...
  3. ncbi request reprint Effect of genome-wide association studies, direct-to-consumer genetic testing, and high-speed sequencing technologies on predictive genetic counselling for cancer risk
    Michael R Speicher
    Medical University of Graz, Institute of Human Genetics, Graz, Austria
    Lancet Oncol 11:890-8. 2010
    ..Here, we use the example of genetic counselling in colon cancer to describe how these developments will change genetic testing in families at risk of cancer and in the general population...