Beate Rinner

Summary

Country: Austria

Publications

  1. pmc Molecular evidence for the bi-clonal origin of neuroendocrine tumor derived metastases
    Beate Rinner
    Center for Medical Research, Medical University of Graz, Stiftingtalstraße 24, Graz, 8010, Austria
    BMC Genomics 13:594. 2012
  2. pmc Chordoma characterization of significant changes of the DNA methylation pattern
    Beate Rinner
    Center for Medical Research, Medical University Graz, Graz, Austria
    PLoS ONE 8:e56609. 2013
  3. doi request reprint Establishment and detailed functional and molecular genetic characterisation of a novel sacral chordoma cell line, MUG-Chor1
    Beate Rinner
    Center for Medical Research, Medical University of Graz, Austria
    Int J Oncol 40:443-51. 2012
  4. doi request reprint The novel myxofibrosarcoma cell line MUG-Myx1 expresses a tumourigenic stem-like cell population with high aldehyde dehydrogenase 1 activity
    Birgit Lohberger
    Department of Orthopaedic Surgery, Medical University of Graz, Auenbruggerplatz 5, A 8036, Graz, Austria
    BMC Cancer 13:563. 2013
  5. pmc Sesquiterpene lactones downregulate G2/M cell cycle regulator proteins and affect the invasive potential of human soft tissue sarcoma cells
    Birgit Lohberger
    Department of Orthopedic Surgery, Medical University of Graz, Graz, Austria
    PLoS ONE 8:e66300. 2013
  6. doi request reprint Tri-lineage potential of intraoral tissue-derived mesenchymal stromal cells
    Birgit Lohberger
    Department of Orthopedic Surgery, Medical University of Graz, Graz, Austria
    J Craniomaxillofac Surg 41:110-8. 2013
  7. doi request reprint Effect of costunolide and dehydrocostus lactone on cell cycle, apoptosis, and ABC transporter expression in human soft tissue sarcoma cells
    Nadine Kretschmer
    Institute of Pharmaceutical Sciences, Department of Pharmacognosy, Karl Franzens University, Graz, Austria
    Planta Med 78:1749-56. 2012
  8. doi request reprint Influence of resveratrol on rheumatoid fibroblast-like synoviocytes analysed with gene chip transcription
    Mathias Glehr
    Department of Orthopaedic Surgery, Medical University of Graz, Graz, Austria
    Phytomedicine 20:310-8. 2013
  9. pmc Effect of cyclic mechanical stimulation on the expression of osteogenesis genes in human intraoral mesenchymal stromal and progenitor cells
    Birgit Lohberger
    Department of Orthopaedic Surgery, Medical University of Graz, Auenbruggerplatz 5, 8036 Graz, Austria
    Biomed Res Int 2014:189516. 2014
  10. doi request reprint Histone deacetylase inhibitors as potential therapeutic approaches for chordoma: an immunohistochemical and functional analysis
    Susanne Scheipl
    Department of Orthopaedics and Orthopaedic Surgery, Medical University of Graz, Auenbruggerplatz 5, 8036, Graz, Austria
    J Orthop Res 31:1999-2005. 2013

Collaborators

Detail Information

Publications16

  1. pmc Molecular evidence for the bi-clonal origin of neuroendocrine tumor derived metastases
    Beate Rinner
    Center for Medical Research, Medical University of Graz, Stiftingtalstraße 24, Graz, 8010, Austria
    BMC Genomics 13:594. 2012
    ....
  2. pmc Chordoma characterization of significant changes of the DNA methylation pattern
    Beate Rinner
    Center for Medical Research, Medical University Graz, Graz, Austria
    PLoS ONE 8:e56609. 2013
    ..These findings add new insights into chordoma development, diagnosis and potential new treatment options...
  3. doi request reprint Establishment and detailed functional and molecular genetic characterisation of a novel sacral chordoma cell line, MUG-Chor1
    Beate Rinner
    Center for Medical Research, Medical University of Graz, Austria
    Int J Oncol 40:443-51. 2012
    ..3-q23.32 (includes the PTEN locus) and losses of 10q25.2 (includes the PDCD4 locus). MUG-Chor1 bears a marked resemblance to chordomas in vivo and is, therefore, an optimal in vitro chordoma model...
  4. doi request reprint The novel myxofibrosarcoma cell line MUG-Myx1 expresses a tumourigenic stem-like cell population with high aldehyde dehydrogenase 1 activity
    Birgit Lohberger
    Department of Orthopaedic Surgery, Medical University of Graz, Auenbruggerplatz 5, A 8036, Graz, Austria
    BMC Cancer 13:563. 2013
    ..These neoplasms mainly affect patients in the sixth to eighth decades of life and the overall 5-year survival rate is 60-70%...
  5. pmc Sesquiterpene lactones downregulate G2/M cell cycle regulator proteins and affect the invasive potential of human soft tissue sarcoma cells
    Birgit Lohberger
    Department of Orthopedic Surgery, Medical University of Graz, Graz, Austria
    PLoS ONE 8:e66300. 2013
    ..In addition, the invasion potential was significantly reduced after treatment with both sesquiterpene lactones as investigated by the HTS FluoroBlock™ insert system. ..
  6. doi request reprint Tri-lineage potential of intraoral tissue-derived mesenchymal stromal cells
    Birgit Lohberger
    Department of Orthopedic Surgery, Medical University of Graz, Graz, Austria
    J Craniomaxillofac Surg 41:110-8. 2013
    ..All sites seem to be potential sources of mesenchymal stromal and progenitor cells for tissue engineering approaches. Therefore, harvest morbidity and patient acceptance should affect the choice of the appropriate site...
  7. doi request reprint Effect of costunolide and dehydrocostus lactone on cell cycle, apoptosis, and ABC transporter expression in human soft tissue sarcoma cells
    Nadine Kretschmer
    Institute of Pharmaceutical Sciences, Department of Pharmacognosy, Karl Franzens University, Graz, Austria
    Planta Med 78:1749-56. 2012
    ..Therefore, this compound may be a promising lead candidate for the development of therapeutic agents against drug-resistant tumours...
  8. doi request reprint Influence of resveratrol on rheumatoid fibroblast-like synoviocytes analysed with gene chip transcription
    Mathias Glehr
    Department of Orthopaedic Surgery, Medical University of Graz, Graz, Austria
    Phytomedicine 20:310-8. 2013
    ..Our in vitro findings point towards resveratrol as a promising new therapeutic approach for local intra-articular application against RA, and further clinical studies will be necessary...
  9. pmc Effect of cyclic mechanical stimulation on the expression of osteogenesis genes in human intraoral mesenchymal stromal and progenitor cells
    Birgit Lohberger
    Department of Orthopaedic Surgery, Medical University of Graz, Auenbruggerplatz 5, 8036 Graz, Austria
    Biomed Res Int 2014:189516. 2014
    ..These results will contribute to a better understanding of strain-induced bone remodelling and will form the basis for the correct choice of applied force in oral and maxillofacial surgery. ..
  10. doi request reprint Histone deacetylase inhibitors as potential therapeutic approaches for chordoma: an immunohistochemical and functional analysis
    Susanne Scheipl
    Department of Orthopaedics and Orthopaedic Surgery, Medical University of Graz, Auenbruggerplatz 5, 8036, Graz, Austria
    J Orthop Res 31:1999-2005. 2013
    ..SAHA and LBH-589 significantly increased apoptosis and changed cell cycle distribution in vitro. HDAC-inhibitors should be further evaluated as therapeutic options for chordoma...
  11. ncbi request reprint The influence of resveratrol on the synovial expression of matrix metalloproteinases and receptor activator of NF-kappaB ligand in rheumatoid arthritis fibroblast-like synoviocytes
    Mathias Glehr
    Department of Orthopaedic Surgery, Medical University of Graz, Auenbruggerplatz 5, A 8036 Graz, Austria
    Z Naturforsch C 68:336-42. 2013
    ..In the future it could play a role as a possible substitute or supplement to currently used drugs against RA to prevent cartilage matrix degradation and pathological bone resorption due to inhibition of MMPs and RANKL...
  12. pmc Resolving tumor heterogeneity: genes involved in chordoma cell development identified by low-template analysis of morphologically distinct cells
    Amin El-Heliebi
    Institute of Pathology, Medical University of Graz, Graz, Austria
    PLoS ONE 9:e87663. 2014
    ..We identified the different chordoma cell phenotypes to be part of a developmental process and discovered new genes linked to chordoma cell development representing potential targets for further research in chordoma tumor biology. ..
  13. ncbi request reprint The influence of glutamate receptors on proliferation and metabolic cell activity of neuroendocrine tumors
    Helga Susanne Haas
    MA, Institute of Pathophysiology and Immunology, Center of Molecular Medicine, Medical University of Graz, Heinrichstrasse 31A, 8010 Graz, Austria
    Anticancer Res 33:1267-72. 2013
    ..These first results indicate that specific metabotropic glutamate receptor antagonists suppress the proliferation and cell activity of neuroendocrine tumor cells, which makes them possible targets in cancer therapy...
  14. doi request reprint Human intraoral harvested mesenchymal stem cells: characterization, multilineage differentiation analysis, and 3-dimensional migration of natural bone mineral and tricalcium phosphate scaffolds
    Birgit Lohberger
    Department of Orthopaedic Surgery, Medical University of Graz, Graz, Austria
    J Oral Maxillofac Surg 70:2309-15. 2012
    ..The aim of this study was the establishment of a minimally invasive technique of mesenchymal stem cell (MSC) harvesting and a predictable isolation and cultivation method on 2 different bone substitutes used as potential scaffolds...
  15. doi request reprint More than cell dust: microparticles isolated from cerebrospinal fluid of brain injured patients are messengers carrying mRNAs, miRNAs, and proteins
    Silke Patz
    Research Unit for Experimental Neurotraumatology, Department of Neurosurgery, Medical University of Graz, Graz, Austria
    J Neurotrauma 30:1232-42. 2013
    ..This first indication of a regulated transport of functional genetic material in human CSF may facilitate the diagnosis and analysis of cerebral modulation in an otherwise inaccessible organ...
  16. pmc Aldehyde dehydrogenase 1, a potential marker for cancer stem cells in human sarcoma
    Birgit Lohberger
    Department of Orthopaedic Surgery, Medical University of Graz, Graz, Austria
    PLoS ONE 7:e43664. 2012
    ..In addition, enhanced drug resistance was demonstrated...