F Horak

Summary

Affiliation: Nose and Throat
Country: Austria

Publications

  1. pmc Effectiveness of twice daily azelastine nasal spray in patients with seasonal allergic rhinitis
    Friedrich Horak
    Medical University Vienna, ENT Univ Clinic, Vienna, Austria
    Ther Clin Risk Manag 4:1009-22. 2008
  2. doi Implementation of pre-seasonal sublingual immunotherapy with a five-grass pollen tablet during optimal dosage assessment
    F Horak
    Department of ENT, Medical University of Vienna, Wahringer Gurtel 18 20, Vienna, Austria
    Clin Exp Allergy 39:394-400. 2009
  3. ncbi Azelastine nasal spray for the treatment of allergic and nonallergic rhinitis
    Friedrich Horak
    , , A 1090 Vienna, Austria
    Expert Rev Clin Immunol 5:659-69. 2009
  4. ncbi Azelastine nasal spray and desloratadine tablets in pollen-induced seasonal allergic rhinitis: a pharmacodynamic study of onset of action and efficacy
    Friedrich Horak
    Ear, Nose and Throat, University Clinic Vienna, Vienna, Austria
    Curr Med Res Opin 22:151-7. 2006
  5. doi The effects of bilastine compared with cetirizine, fexofenadine, and placebo on allergen-induced nasal and ocular symptoms in patients exposed to aeroallergen in the Vienna Challenge Chamber
    Friedrich Horak
    ENT Department, Medical University Vienna, Waehringer Guertel 18, 1090, Vienna, Austria
    Inflamm Res 59:391-8. 2010
  6. pmc Levocetirizine has a longer duration of action on improving total nasal symptoms score than fexofenadine after single administration
    Friedrich Horak
    Vienna General Hospital AKH, Department of Otorhinolaryngology, Vienna, Austria
    Br J Clin Pharmacol 60:24-31. 2005
  7. doi Early onset of action of a 5-grass-pollen 300-IR sublingual immunotherapy tablet evaluated in an allergen challenge chamber
    Friedrich Horak
    ENT Department, Medical University Vienna, Vienna, Austria
    J Allergy Clin Immunol 124:471-7, 477.e1. 2009
  8. ncbi Comparison of purified Dermatophagoides pteronyssinus allergens and extract by two-dimensional immunoblotting and quantitative immunoglobulin E inhibitions
    M Weghofer
    Division of Immunopathology, Department of Pathophysiology, Center for Physiology and Pathophysiology, Medical University of Vienna, Vienna, Austria
    Clin Exp Allergy 35:1384-91. 2005
  9. doi Association of allergic patients' phenotypes with IgE reactivity to recombinant pollen marker allergens
    A Twardosz-Kropfmüller
    Division of Immunopathology, Department of Pathophysiology, Center for Physiology and Pathophysiology, Medical University of Vienna, Vienna, Austria
    Allergy 65:296-303. 2010
  10. doi Variability of IgE reactivity profiles among European mite allergic patients
    M Weghofer
    Division of Immunopathology, Department of Pathophysiology, Centre for Physiology and Pathophysiology, Medical University of Vienna, Austria
    Eur J Clin Invest 38:959-65. 2008

Collaborators

Detail Information

Publications26

  1. pmc Effectiveness of twice daily azelastine nasal spray in patients with seasonal allergic rhinitis
    Friedrich Horak
    Medical University Vienna, ENT Univ Clinic, Vienna, Austria
    Ther Clin Risk Manag 4:1009-22. 2008
    ..Bitter taste which seems to be associated with incorrect dosing technique is the most common side effect reported by patients, but this problem can be minimized by correct dosing technique...
  2. doi Implementation of pre-seasonal sublingual immunotherapy with a five-grass pollen tablet during optimal dosage assessment
    F Horak
    Department of ENT, Medical University of Vienna, Wahringer Gurtel 18 20, Vienna, Austria
    Clin Exp Allergy 39:394-400. 2009
    ..The optimal dose (300IR) of a five-grass pollen sublingual immunotherapy tablet in terms of efficacy was previously demonstrated from the first pollen season...
  3. ncbi Azelastine nasal spray for the treatment of allergic and nonallergic rhinitis
    Friedrich Horak
    , , A 1090 Vienna, Austria
    Expert Rev Clin Immunol 5:659-69. 2009
    ..Azelastine nasal spray has an excellent safety profile...
  4. ncbi Azelastine nasal spray and desloratadine tablets in pollen-induced seasonal allergic rhinitis: a pharmacodynamic study of onset of action and efficacy
    Friedrich Horak
    Ear, Nose and Throat, University Clinic Vienna, Vienna, Austria
    Curr Med Res Opin 22:151-7. 2006
    ..To assess the efficacy and onset of action of azelastine nasal spray and desloratadine tablets in patients with allergen-induced seasonal allergic rhinitis (SAR)...
  5. doi The effects of bilastine compared with cetirizine, fexofenadine, and placebo on allergen-induced nasal and ocular symptoms in patients exposed to aeroallergen in the Vienna Challenge Chamber
    Friedrich Horak
    ENT Department, Medical University Vienna, Waehringer Guertel 18, 1090, Vienna, Austria
    Inflamm Res 59:391-8. 2010
    ..This double-blind cross-over study compared the potential of bilastine, cetirizine, and fexofenadine to relieve the symptoms of allergic rhinitis...
  6. pmc Levocetirizine has a longer duration of action on improving total nasal symptoms score than fexofenadine after single administration
    Friedrich Horak
    Vienna General Hospital AKH, Department of Otorhinolaryngology, Vienna, Austria
    Br J Clin Pharmacol 60:24-31. 2005
    ..The latter is an environment where subjects can be exposed to specific aeroallergens in controlled and reproducible conditions allowing for precise comparisons of anti-allergic drugs...
  7. doi Early onset of action of a 5-grass-pollen 300-IR sublingual immunotherapy tablet evaluated in an allergen challenge chamber
    Friedrich Horak
    ENT Department, Medical University Vienna, Vienna, Austria
    J Allergy Clin Immunol 124:471-7, 477.e1. 2009
    ..The allergen challenge chamber (ACC) has been developed as a pharmacodynamic assessment tool to control the environmental allergens and to avoid all problems associated with unpredictable pollen seasons...
  8. ncbi Comparison of purified Dermatophagoides pteronyssinus allergens and extract by two-dimensional immunoblotting and quantitative immunoglobulin E inhibitions
    M Weghofer
    Division of Immunopathology, Department of Pathophysiology, Center for Physiology and Pathophysiology, Medical University of Vienna, Vienna, Austria
    Clin Exp Allergy 35:1384-91. 2005
    ..These variations may influence allergenic activity and thus may have impact on diagnostic tests and specific immunotherapy...
  9. doi Association of allergic patients' phenotypes with IgE reactivity to recombinant pollen marker allergens
    A Twardosz-Kropfmüller
    Division of Immunopathology, Department of Pathophysiology, Center for Physiology and Pathophysiology, Medical University of Vienna, Vienna, Austria
    Allergy 65:296-303. 2010
    ..The aim of this study was to investigate whether IgE reactivity to recombinant pollen allergens with broad and narrow cross-reactivity is associated with clinical phenotypes of allergic sensitization...
  10. doi Variability of IgE reactivity profiles among European mite allergic patients
    M Weghofer
    Division of Immunopathology, Department of Pathophysiology, Centre for Physiology and Pathophysiology, Medical University of Vienna, Austria
    Eur J Clin Invest 38:959-65. 2008
    ..Our aim was to determine the frequencies of IgE reactivity to purified HDM allergen molecules in mite allergic patients from different parts of Europe in order to establish an allergen panel for diagnosis of HDM allergy...
  11. ncbi Skin test results but not serology reflect immediate type respiratory sensitivity: a study performed with recombinant allergen molecules
    V Niederberger
    Department of Otorhinolaryngology, University of Vienna, Austria
    J Invest Dermatol 117:848-51. 2001
    ..These results have implications for allergy diagnosis and, in particular, for the selection of relevant allergen components for specific immunotherapy...
  12. doi Molecular characterization of Der p 10: a diagnostic marker for broad sensitization in house dust mite allergy
    Y Resch
    Division of Immunopathology, Department of Pathophysiology and Allergy Research, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, AustriaAllergy Centre Vienna West, Vienna, Austria
    Clin Exp Allergy 41:1468-77. 2011
    ..Tropomyosins represent clinically relevant seafood allergens but the role of mite tropomyosin, Der p 10, in house dust mite (HDM) allergy has not been studied in detail...
  13. doi Characterization of Der p 21, a new important allergen derived from the gut of house dust mites
    M Weghofer
    Division of Immunopathology, Department of Pathophysiology, Center for Physiology and Pathophysiology, Medical University of Vienna, Vienna, Austria
    Allergy 63:758-67. 2008
    ..The house dust mite (HDM) Dermatophagoides pteronyssinus is a major allergen source eliciting allergic asthma. The aim of the study was to identify new important HDM allergens associated with allergic asthma...
  14. ncbi Comparison of the effects of desloratadine 5-mg daily and placebo on nasal airflow and seasonal allergic rhinitis symptoms induced by grass pollen exposure
    F Horak
    ENT Universitätsklinik, Vienna, Austria
    Allergy 58:481-5. 2003
    ..We compared the effects of desloratadine 5 mg and placebo on nasal airflow, nasal secretion weights and SAR symptoms, including nasal congestion, in patients exposed to grass pollen in an environmental exposure unit...
  15. doi The allergen profile of beech and oak pollen
    C Egger
    Christian Doppler Laboratory for Allergy Research, Division of Immunopathology, Department of Pathophysiology, Center for Physiology and Pathophysiology, Medical University of Vienna, Vienna, Austria
    Clin Exp Allergy 38:1688-96. 2008
    ..Beech and oak pollen are potential allergen sources with a world-wide distribution...
  16. doi Different allergenic activity of grass pollen allergens revealed by skin testing
    K Westritschnig
    Medical University of Vienna, Austria
    Eur J Clin Invest 38:260-7. 2008
    ....
  17. ncbi Efficacy and safety of an oral formulation of cetirizine and prolonged-release pseudoephedrine versus xylometazoline nasal spray in nasal congestion
    U P Stübner
    Ear Nose Throat University Clinic, Vienna, Austria
    Arzneimittelforschung 51:904-10. 2001
    ..With the exception of nasal obstruction, all subjective symptoms as well as the global condition were significantly better under CTZ/PSE. Amounts of nasal secretions during these sessions were significantly lower with CTZ/PSE...
  18. pmc Vaccination with genetically engineered allergens prevents progression of allergic disease
    V Niederberger
    Department of Otorhinolaryngology, Vienna General Hospital, University of Vienna, 1090 Vienna, Austria
    Proc Natl Acad Sci U S A 101:14677-82. 2004
    ..Vaccination with genetically engineered allergen derivatives is a therapy for allergy that not only ameliorates allergic reactions but also reduces the IgE production underlying the disease...
  19. doi The CRTH2 antagonist OC000459 reduces nasal and ocular symptoms in allergic subjects exposed to grass pollen, a randomised, placebo-controlled, double-blind trial
    F Horak
    Vienna Challenge Chamber, Allergy Centre Vienna West, Vienna, Austria
    Allergy 67:1572-9. 2012
    ..The objective of the present study was to determine the involvement of CRTH2 in promoting nasal and ocular symptoms in allergic subjects exposed to grass pollen...
  20. doi Patients suffering from non-IgE-mediated cow's milk protein intolerance cannot be diagnosed based on IgG subclass or IgA responses to milk allergens
    H Hochwallner
    Department of Medical and Chemical Laboratory Diagnostics, Medical University of Vienna, Vienna, Austria
    Allergy 66:1201-7. 2011
    ....
  21. ncbi Pharmacodynamic dose finding of dimetindene in a sustained release formulation
    F Horak
    HNO Universitätsklinik, Vienna, Austria
    Arzneimittelforschung 43:1193-5. 1993
    ..Therefore 4 mg dimetindene once a day is the adequate treatment for usual pollinotic disease conditions...
  22. ncbi Effect of mite-impermeable mattress encasings and an educational package on the development of allergies in a multinational randomized, controlled birth-cohort study -- 24 months results of the Study of Prevention of Allergy in Children in Europe
    F Horak
    University Children s Hospital, Vienna, Austria
    Clin Exp Allergy 34:1220-5. 2004
    ..Sensitization to house dust mite (HDM) is an important risk factor for the development of asthma and allergic disease in childhood. Higher levels of HDM allergen are linked to increased sensitization to HDM...
  23. ncbi Component-resolved diagnosis of house-dust mite allergy with purified natural and recombinant mite allergens
    G Pittner
    Division of Immunopathology, Department of Pathophysiology, Vienna General Hospital, Medical University of Vienna, Austria
    Clin Exp Allergy 34:597-603. 2004
    ..Immunotherapy with mite allergen extracts is frequently performed if allergen avoidance is not possible or successful. However, highly controversial results have been reported for mite-specific immunotherapy...
  24. ncbi Clinical advantages of dual activity in allergic rhinitis
    F Horak
    ENT Clinic, University Hospital, Vienna, Austria
    Allergy 55:34-9. 2000
    ..These effects were maintained over a 5-month treatment period. Mizolastine has also been shown to be at least as effective as loratadine, and in one trial even superior in the treatment of perennial allergic rhinitis...
  25. ncbi Upper airway findings in patients with nocturnal breathing disorders
    A F Temmel
    Department of Otorhinolaryngology, Head and Neck Surgery, University of Vienna, AKH Wien, Austria
    Wien Klin Wochenschr 112:767-71. 2000
    ..The more pathologies were found the higher was the risk of obstructive sleep apnoea with desaturation below 70%. Unrelated tonsillectomy (51.36%) did not prevent nocturnal breathing disorders...
  26. ncbi Impact and modulation of nasal obstruction
    F Horak
    Ear, Nose, and Throat Clinic, Vienna, Austria
    Allergy 57:25-8. 2002
    ..05) and in the mean severity score for the symptom of nasal obstruction (P < 0.03). Desloratadine significantly reduces the severity of nasal obstruction in patients with seasonal allergic rhinitis...