Research Topics
| F HorakSummaryAffiliation: Nose and Throat Country: Austria Publications
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Detail Information
Publications
Azelastine nasal spray and desloratadine tablets in pollen-induced seasonal allergic rhinitis: a pharmacodynamic study of onset of action and efficacyFriedrich Horak
Ear, Nose and Throat, University Clinic Vienna, Vienna, Austria
Curr Med Res Opin 22:151-7. 2006..To assess the efficacy and onset of action of azelastine nasal spray and desloratadine tablets in patients with allergen-induced seasonal allergic rhinitis (SAR)...
Implementation of pre-seasonal sublingual immunotherapy with a five-grass pollen tablet during optimal dosage assessmentF Horak
Department of ENT, Medical University of Vienna, Wahringer Gurtel 18 20, Vienna, Austria
Clin Exp Allergy 39:394-400. 2009..The optimal dose (300IR) of a five-grass pollen sublingual immunotherapy tablet in terms of efficacy was previously demonstrated from the first pollen season...
Levocetirizine has a longer duration of action on improving total nasal symptoms score than fexofenadine after single administrationFriedrich Horak
Vienna General Hospital AKH, Department of Otorhinolaryngology, Vienna, Austria
Br J Clin Pharmacol 60:24-31. 2005..The latter is an environment where subjects can be exposed to specific aeroallergens in controlled and reproducible conditions allowing for precise comparisons of anti-allergic drugs...- Early onset of action of a 5-grass-pollen 300-IR sublingual immunotherapy tablet evaluated in an allergen challenge chamberFriedrich Horak
ENT Department, Medical University Vienna, Vienna, Austria
J Allergy Clin Immunol 124:471-7, 477.e1. 2009..The allergen challenge chamber (ACC) has been developed as a pharmacodynamic assessment tool to control the environmental allergens and to avoid all problems associated with unpredictable pollen seasons... - The effects of bilastine compared with cetirizine, fexofenadine, and placebo on allergen-induced nasal and ocular symptoms in patients exposed to aeroallergen in the Vienna Challenge ChamberFriedrich Horak
ENT Department, Medical University Vienna, Waehringer Guertel 18, 1090, Vienna, Austria
Inflamm Res 59:391-8. 2010..This double-blind cross-over study compared the potential of bilastine, cetirizine, and fexofenadine to relieve the symptoms of allergic rhinitis... - Azelastine nasal spray for the treatment of allergic and nonallergic rhinitisFriedrich Horak
, , A 1090 Vienna, Austria
Expert Rev Clin Immunol 5:659-69. 2009..Azelastine nasal spray has an excellent safety profile... - Association of allergic patients' phenotypes with IgE reactivity to recombinant pollen marker allergensA Twardosz-Kropfmüller
Division of Immunopathology, Department of Pathophysiology, Center for Physiology and Pathophysiology, Medical University of Vienna, Vienna, Austria
Allergy 65:296-303. 2010..The aim of this study was to investigate whether IgE reactivity to recombinant pollen allergens with broad and narrow cross-reactivity is associated with clinical phenotypes of allergic sensitization... - Variability of IgE reactivity profiles among European mite allergic patientsM Weghofer
Division of Immunopathology, Department of Pathophysiology, Centre for Physiology and Pathophysiology, Medical University of Vienna, Austria
Eur J Clin Invest 38:959-65. 2008..Our aim was to determine the frequencies of IgE reactivity to purified HDM allergen molecules in mite allergic patients from different parts of Europe in order to establish an allergen panel for diagnosis of HDM allergy... - Comparison of purified Dermatophagoides pteronyssinus allergens and extract by two-dimensional immunoblotting and quantitative immunoglobulin E inhibitionsM Weghofer
Division of Immunopathology, Department of Pathophysiology, Center for Physiology and Pathophysiology, Medical University of Vienna, Vienna, Austria
Clin Exp Allergy 35:1384-91. 2005..CONCLUSION: The studied recombinant and natural mite allergens contain a large portion of Der p-specific IgE and may be used for diagnostic tests and therapy of Der p allergy... - Skin test results but not serology reflect immediate type respiratory sensitivity: a study performed with recombinant allergen moleculesV Niederberger
Department of Otorhinolaryngology, University of Vienna, Austria
J Invest Dermatol 117:848-51. 2001..These results have implications for allergy diagnosis and, in particular, for the selection of relevant allergen components for specific immunotherapy... - Molecular characterization of Der p 10: a diagnostic marker for broad sensitization in house dust mite allergyY Resch
Division of Immunopathology, Department of Pathophysiology and Allergy Research, Center for Pathophysiology, Infectiology and Immunology, Medical University of Vienna, Vienna, AustriaAllergy Centre Vienna West, Vienna, Austria
Clin Exp Allergy 41:1468-77. 2011..Tropomyosins represent clinically relevant seafood allergens but the role of mite tropomyosin, Der p 10, in house dust mite (HDM) allergy has not been studied in detail... - Comparison of the effects of desloratadine 5-mg daily and placebo on nasal airflow and seasonal allergic rhinitis symptoms induced by grass pollen exposureF Horak
, Vienna, Austria
Allergy 58:481-5. 2003.... - Different allergenic activity of grass pollen allergens revealed by skin testingK Westritschnig
Medical University of Vienna, Austria
Eur J Clin Invest 38:260-7. 2008.... - Efficacy and safety of an oral formulation of cetirizine and prolonged-release pseudoephedrine versus xylometazoline nasal spray in nasal congestionU P Stübner
Ear Nose Throat University Clinic, Vienna, Austria
Arzneimittelforschung 51:904-10. 2001..With the exception of nasal obstruction, all subjective symptoms as well as the global condition were significantly better under CTZ/PSE. Amounts of nasal secretions during these sessions were significantly lower with CTZ/PSE... - Vaccination with genetically engineered allergens prevents progression of allergic diseaseV Niederberger
Department of Otorhinolaryngology, Vienna General Hospital, University of Vienna, 1090 Vienna, Austria
Proc Natl Acad Sci U S A 101:14677-82. 2004..Vaccination with genetically engineered allergen derivatives is a therapy for allergy that not only ameliorates allergic reactions but also reduces the IgE production underlying the disease... - The allergen profile of beech and oak pollenC Egger
Christian Doppler Laboratory for Allergy Research, Division of Immunopathology, Department of Pathophysiology, Center for Physiology and Pathophysiology, Medical University of Vienna, Vienna, Austria
Clin Exp Allergy 38:1688-96. 2008..Beech and oak pollen are potential allergen sources with a world-wide distribution... - The CRTH2 antagonist OC000459 reduces nasal and ocular symptoms in allergic subjects exposed to grass pollen, a randomised, placebo-controlled, double-blind trialF Horak
Vienna Challenge Chamber, Allergy Centre Vienna West, Vienna, Austria
Allergy 67:1572-9. 2012..The objective of the present study was to determine the involvement of CRTH2 in promoting nasal and ocular symptoms in allergic subjects exposed to grass pollen... - Characterization of Der p 21, a new important allergen derived from the gut of house dust mitesM Weghofer
Division of Immunopathology, Department of Pathophysiology, Center for Physiology and Pathophysiology, Medical University of Vienna, Vienna, Austria
Allergy 63:758-67. 2008..The house dust mite (HDM) Dermatophagoides pteronyssinus is a major allergen source eliciting allergic asthma. The aim of the study was to identify new important HDM allergens associated with allergic asthma... - Patients suffering from non-IgE-mediated cow's milk protein intolerance cannot be diagnosed based on IgG subclass or IgA responses to milk allergensH Hochwallner
Department of Medical and Chemical Laboratory Diagnostics, Medical University of Vienna, Vienna, Austria
Allergy 66:1201-7. 2011.... - Pharmacodynamic dose finding of dimetindene in a sustained release formulationF Horak
HNO Universitätsklinik, Vienna, Austria
Arzneimittelforschung 43:1193-5. 1993..Therefore 4 mg dimetindene once a day is the adequate treatment for usual pollinotic disease conditions... - Effect of mite-impermeable mattress encasings and an educational package on the development of allergies in a multinational randomized, controlled birth-cohort study -- 24 months results of the Study of Prevention of Allergy in Children in EuropeF Horak
University Children's Hospital, Vienna, Austria
Clin Exp Allergy 34:1220-5. 2004..25.8%) could be found between the control and intervention group. CONCLUSION: In this study, HDM avoidance did not show a protective effect on the development of sensitization to HDM or symptomatic allergy in children at age 24 months... - Component-resolved diagnosis of house-dust mite allergy with purified natural and recombinant mite allergensG Pittner
Division of Immunopathology, Department of Pathophysiology, Vienna General Hospital, Medical University of Vienna, Austria
Clin Exp Allergy 34:597-603. 2004..g. Der p 10) may improve the diagnostic selection of patients for immunotherapy with Der p extracts. These tests may also be used for the immunological monitoring of patients undergoing immunotherapy... - Clinical advantages of dual activity in allergic rhinitisF Horak
ENT Clinic, University Hospital, Vienna, Austria
Allergy 55:34-9. 2000..These effects were maintained over a 5-month treatment period. Mizolastine has also been shown to be at least as effective as loratadine, and in one trial even superior in the treatment of perennial allergic rhinitis... - Upper airway findings in patients with nocturnal breathing disordersA F Temmel
Department of Otorhinolaryngology, Head and Neck Surgery, University of Vienna, AKH Wien, Austria
Wien Klin Wochenschr 112:767-71. 2000..The more pathologies were found the higher was the risk of obstructive sleep apnoea with desaturation below 70%. Unrelated tonsillectomy (51.36%) did not prevent nocturnal breathing disorders... - Impact and modulation of nasal obstructionF Horak
Ear, Nose, and Throat Clinic, Vienna, Austria
Allergy 57:25-8. 2002..05) and in the mean severity score for the symptom of nasal obstruction (P < 0.03). Desloratadine significantly reduces the severity of nasal obstruction in patients with seasonal allergic rhinitis...