Research Topics
Species | G P TilzSummaryAffiliation: Medical University of Graz Country: Austria Publications
| Collaborators
|
Detail Information
Publications
On the occurrence of the diabetes-associated antigen GAD 65 in human seraG P Tilz
Medical University of Graz, Graz, Austria
Int Arch Allergy Immunol 155:167-79. 2011..In this study we demonstrate its appearance in 64 human sera samples representing a cross-section of a blood bank...
The diabetic antigen glutamic acid decarboxylase (GAD 65) in the human peripheral bloodG P Tilz
Centre d Etude du Polymorphysme Humain, Paris, France
Int Arch Allergy Immunol 152:184-94. 2010..In order to better understand autoimmunity, this study demonstrates the appearance of GAD 65 in the peripheral human blood and presents implications for the diagnosis and therapy of some autoimmune diseases...
Insights into molecular medicine: development of new diagnostic and prognostic parametersGernot P Tilz
Clinical Immunology and Jean Dausset Laboratory, Medical University of Graz, Auenbruggerplatz 8, 8036 Graz, Austria
Wien Med Wochenschr 157:122-9. 2007..In view of the spectrum of parameters relevant to clinical entities, multiplexing is a new way of development. Since the technologies are new, the scientifically interested reader should be informed about the matters arising...
[Sense and nonsense in antibiotic therapy for respiratory tract infections]W Domej
Klinische Abteilung für Pulmonologie, Medizinische Universitätsklinik Graz, Osterreich
Internist (Berl) 46:795-9. 2005..This paper considers rational and irrational measures in the antimicrobial therapy of respiratory infections...
Ultrasensitive detection and identification of fluorescent molecules by FCS: impact for immunobiologyZ Földes-Papp
Clinical Immunology and Jean Dausset Laboratory, Graz University Medical School and Hospital, Auenbruggerplatz 8, A 8036 Graz, LKH, Austria
Proc Natl Acad Sci U S A 98:11509-14. 2001..Our results open up a broad field for analytics and diagnostics in solution, especially in immunology...
Enhancing sensitivity of human herpes virus diagnosis with DNA microarrays using dendrimersHans-Martin Striebel
Institute for Molecular Biotechnology, Jena D-07745, Germany
Exp Mol Pathol 77:89-97. 2004....
DNA microarray analysis: principles and clinical impactMarco Wiltgen
Institute of Medical Informatics, Statistics and Documentation, Medical University of Graz, Graz, Austria
Hematology 12:271-87. 2007..In this introductory paper, we present the principles of DNA microarray experiments, selected clustering methods for gene expression analysis and the impact to clinical research...
A new dimension for the development of fluorescence-based assays in solution: from physical principles of FCS detection to biological applicationsZeno Földes-Papp
Clinical Immunology and Jean Dausset Laboratory, Graz University Medical School and Hospital, Auenbruggerplatz 8, A 8036 Graz, LKH, Austria
Exp Biol Med (Maywood) 227:291-300. 2002..This article is mandatory for gaining confidence in the interpretation of experimental SPSM-FCS results on the selfsame, individual single molecule in solution...
[Aspects and necessity of moderate-altitude research]Wolfgang Domej
Medizinische Universitatsklinik, Medizinische Universitat Graz, Graz, Osterreich
Wien Med Wochenschr 155:149-56. 2005..It is imperative that mountain medicine continues to develop on a scientific basis...
Oxidative stress caused by acute and chronic exposition to altitudeZeno Földes-Papp
Clinical Immunology and Jean Dausset Laboratory, ARGE Alpine Medicine, Medical University of Graz, Graz, Austria
Wien Med Wochenschr 155:136-42. 2005....
Lack of specific immunological disease pattern in vulvar lichen sclerosusZeno Földes-Papp
Clinical Immunology and Jean Dausset Laboratory, Medical University of Graz, Auenbruggerplatz 8, A 8036 Graz LKH, Austria
Exp Mol Pathol 79:176-85. 2005..This may be especially true of such diseases as vulvar LS, where local skin scarring might represent a local tissue response secondary to an initial insult by immune or other processes...
A new ultrasensitive way to circumvent PCR-based allele distinction: direct probing of unamplified genomic DNA by solution-phase hybridization using two-color fluorescence cross-correlation spectroscopyZeno Földes-Papp
Clinical Immunology and Jean Dausset Laboratory, Medical University of Graz, Auenbruggerplatz 8, A 8036 Graz, LKH, Austria
Exp Mol Pathol 78:177-89. 2005..Furthermore, the results present an alternative to existing hybridization approaches that are currently used with and without amplification at the 'many-molecule' level and the 'single-molecule' level...
C677T single nucleotide polymorphisms of the human methylene tetrahydrofolate reductase and specific identification : a novel strategy using two-color cross-correlation fluorescence spectroscopyZeno Földes-Papp
Clinical Immunology and Jean Dausset Laboratory, Graz University Medical School and Hospital, Graz, Austria
Mol Diagn 7:99-111. 2003..Highly specific identification techniques for genotyping are mandatory to give guidance for the diagnosis and monitoring of this deficiency...
Specifically associated PCR products probed by coincident detection of two-color cross-correlated fluorescence intensities in human gene polymorphisms of methylene tetrahydrofolate reductase at site C677T: a novel measurement approach without follow-up maZeno Földes-Papp
Clinical Immunology and Jean Dausset Laboratory, Graz University Medical School and Hospital, A 8036 Graz, LKH, Austria
Exp Mol Pathol 76:212-8. 2004..Under those experimental conditions, a new ultrasensitive, and specific method for clinical immunologists is born...
A new concept for ultrasensitive fluorescence measurements of molecules in solution and membrane: 2. The individual immune moleculeZeno Földes-Papp
Clinical Immunology and Jean Dausset Laboratory, Graz University Medical School and Hospital, Auenbruggerplatz 8, A 8036 Graz, LKH, Austria
J Immunol Methods 286:13-20. 2004..The novel universal theoretical and experimental framework for continuous measuring the same single, individual immune molecule can be readily transferred to other applications...
Counting and behavior of an individual fluorescent molecule without hydrodynamic flow, immobilization, or photon count statisticsZeno Földes-Papp
Clinical Immunology and Jean Dausset Laboratory, Graz University Medical School and Hospital, Auenbruggerplatz 8, A 8036 Graz, LKH, Austria
Curr Pharm Biotechnol 5:163-72. 2004..As technology continues to improve, the limits of what FCS/FCCS is being asked to do are concomitantly pushed...
Detection of multiple human herpes viruses by DNA microarray technologyZeno Földes-Papp
Clinical Immunology and Jean Dausset Laboratory, Graz University Medical School, Graz, Austria
Mol Diagn 8:1-9. 2004....
Detection of single molecules: solution-phase single-molecule fluorescence correlation spectroscopy as an ultrasensitive, rapid and reliable system for immunological investigationZeno Földes-Papp
Clinical Immunology and Jean Dausset Laboratory, Graz University M S and Hospital, Auenbruggerplatz 8, A 8036, LKH, Graz, Austria
J Immunol Methods 260:117-24. 2002..The specific molecules exhibited a Poisson distribution in solution in terms of their 'critical' bulk concentration below about 1 nM. This proof of principle indicates how the SPSM-FCS methodology could be used in immunoassays...
A new concept for ultrasensitive fluorescence measurements of molecules in solution and membrane: 1. Theory and a first applicationZeno Földes-Papp
Clinical Immunology and Jean Dausset Laboratory, Graz University Medical School and Hospital, Auenbruggerplatz 8, A 8036 Graz, LKH, Austria
J Immunol Methods 286:1-11. 2004..From the diffusion coefficient of the molecule, it was found that the probability of the molecule diffusing out of the probe volume during the measurements was negligibly small...
