Zsolt Szepfalusi

Summary

Affiliation: Medical University of Vienna
Country: Austria

Publications

  1. doi Clinical practice: Allergen-specific immunotherapy in children: facts and FAQs
    Zsolt Szepfalusi
    Division of Pediatric Pneumology, Department of Pediatrics, Medical University of Vienna, Wahringer Gurtel 18 20, 1090 Vienna, Austria
    Eur J Pediatr 170:137-48. 2011
  2. doi [Food allergy in childhood]
    Z Szepfalusi
    Medizinische Universität Wien, Wahringer Gurtel 18 20, 1090, Wien, Osterreich
    Wien Med Wochenschr 162:525-32. 2012
  3. doi [Allergen-specific Immunotherapy for children and adolescents - a review on available products in Austria]
    Zsolt Szepfalusi
    Univ Klinik für Kinder und Jugendheilkunde, Austria
    Wien Klin Wochenschr 121:648-60. 2009
  4. ncbi Most of diaplacentally transferred allergen is retained in the placenta
    Z Szepfalusi
    Department of Pediatrics and Juvenile Medicine, Medical University of Vienna, Vienna, Austria
    Clin Exp Allergy 36:1130-7. 2006
  5. ncbi The maturation of the fetal and neonatal immune system
    Zsolt Szepfalusi
    Department of Pediatrics, Medical University of Vienna, Wahringer Gurtel 18 20, A 1090 Vienna, Austria
    J Nutr 138:1773S-1781S. 2008
  6. ncbi Human milk--derived oligosaccharides and plant-derived oligosaccharides stimulate cytokine production of cord blood T-cells in vitro
    Thomas Eiwegger
    Department of Pediatrics and Juvenile Medicine, University of Vienna, Medical School, A 1090 Vienna, Austria
    Pediatr Res 56:536-40. 2004
  7. ncbi Immunosuppressive therapy does not prevent the occurrence of immunoglobulin E-mediated allergies in children and adolescents with organ transplants
    Eleonora Dehlink
    Department of Pediatrics and Adolescent Medicine, Division of General Pediatrics, Medical University of Vienna, Waehringer Guertel 18 20, A 1090 Vienna, Austria
    Pediatrics 118:e764-70. 2006
  8. doi A Th17- and Th2-skewed cytokine profile in cystic fibrosis lungs represents a potential risk factor for Pseudomonas aeruginosa infection
    Kerstin Tiringer
    Department of Pediatrics and Adolescent Medicine, Medical University of Vienna, Waehringer Guertel 18 20, Vienna, Austria
    Am J Respir Crit Care Med 187:621-9. 2013
  9. ncbi Dose-dependent and preterm- accentuated diaplacental transport of nutritive allergens in vitro
    Monika Edelbauer
    Department of Pediatrics, University of Vienna, Austria
    Int Arch Allergy Immunol 130:25-32. 2003
  10. ncbi 1 alpha,25(OH)2D3 inhibits not only Th1 but also Th2 differentiation in human cord blood T cells
    Josefa Pichler
    Department of Pediatrics, University of Vienna, A 1090 Vienna, Austria
    Pediatr Res 52:12-8. 2002

Collaborators

Detail Information

Publications19

  1. doi Clinical practice: Allergen-specific immunotherapy in children: facts and FAQs
    Zsolt Szepfalusi
    Division of Pediatric Pneumology, Department of Pediatrics, Medical University of Vienna, Wahringer Gurtel 18 20, 1090 Vienna, Austria
    Eur J Pediatr 170:137-48. 2011
    ..IgE-mediated allergic diseases are affecting about 20% of the population. They manifest commonly early in life, and hence, the use of SIT should be considered also early in the course of the disease...
  2. doi [Food allergy in childhood]
    Z Szepfalusi
    Medizinische Universität Wien, Wahringer Gurtel 18 20, 1090, Wien, Osterreich
    Wien Med Wochenschr 162:525-32. 2012
    ..Treatment of food allergy involves strict avoidance of the trigger food. Medications help to manage symptoms of disease, but currently, there is no cure for food allergy...
  3. doi [Allergen-specific Immunotherapy for children and adolescents - a review on available products in Austria]
    Zsolt Szepfalusi
    Univ Klinik für Kinder und Jugendheilkunde, Austria
    Wien Klin Wochenschr 121:648-60. 2009
    ..In addition, the use of allergen-specific immunotherapy in general should be promoted as the exclusive treatment with long-lasting effects in type I allergies in particular in children...
  4. ncbi Most of diaplacentally transferred allergen is retained in the placenta
    Z Szepfalusi
    Department of Pediatrics and Juvenile Medicine, Medical University of Vienna, Vienna, Austria
    Clin Exp Allergy 36:1130-7. 2006
    ..As such, cord blood T cell responses appear ubiquitously. However, studies failed to reveal a consistent dose-response relationship between antenatal allergen exposure and allergen-specific cellular reactivity in cord blood...
  5. ncbi The maturation of the fetal and neonatal immune system
    Zsolt Szepfalusi
    Department of Pediatrics, Medical University of Vienna, Wahringer Gurtel 18 20, A 1090 Vienna, Austria
    J Nutr 138:1773S-1781S. 2008
    ..Examples of the latter, discussed below, are elements of innate and adaptive immune function and aspects of food allergy and of airway function relevant to atopic asthma...
  6. ncbi Human milk--derived oligosaccharides and plant-derived oligosaccharides stimulate cytokine production of cord blood T-cells in vitro
    Thomas Eiwegger
    Department of Pediatrics and Juvenile Medicine, University of Vienna, Medical School, A 1090 Vienna, Austria
    Pediatr Res 56:536-40. 2004
    ..Therefore, oligosaccharides and, in particular, acidic oligosaccharides may influence lymphocyte maturation in breast-fed newborns...
  7. ncbi Immunosuppressive therapy does not prevent the occurrence of immunoglobulin E-mediated allergies in children and adolescents with organ transplants
    Eleonora Dehlink
    Department of Pediatrics and Adolescent Medicine, Division of General Pediatrics, Medical University of Vienna, Waehringer Guertel 18 20, A 1090 Vienna, Austria
    Pediatrics 118:e764-70. 2006
    ..Thus far, mainly case reports and series on the occurrence of allergy after orthotopic liver transplantation exist...
  8. doi A Th17- and Th2-skewed cytokine profile in cystic fibrosis lungs represents a potential risk factor for Pseudomonas aeruginosa infection
    Kerstin Tiringer
    Department of Pediatrics and Adolescent Medicine, Medical University of Vienna, Waehringer Guertel 18 20, Vienna, Austria
    Am J Respir Crit Care Med 187:621-9. 2013
    ..Cystic fibrosis (CF) is characterized by progressive pulmonary inflammation that is infection-triggered. Pseudomonas aeruginosa represents a risk factor for deterioration of lung function and reduced life expectancy...
  9. ncbi Dose-dependent and preterm- accentuated diaplacental transport of nutritive allergens in vitro
    Monika Edelbauer
    Department of Pediatrics, University of Vienna, Austria
    Int Arch Allergy Immunol 130:25-32. 2003
    ..We investigated the role of different allergen concentrations in influencing the diaplacental allergen transport in preterm and term placentas...
  10. ncbi 1 alpha,25(OH)2D3 inhibits not only Th1 but also Th2 differentiation in human cord blood T cells
    Josefa Pichler
    Department of Pediatrics, University of Vienna, A 1090 Vienna, Austria
    Pediatr Res 52:12-8. 2002
    ..Thus, in cord blood 1 alpha, 25(OH)2D3 induces a T cell population without predominance of Th2 related cytokines...
  11. pmc Novel developments in the mechanisms of immune tolerance to allergens
    Thomas Eiwegger
    Department of Pediatrics and Adolescent Medicine, Medical University of Vienna, Austria
    Hum Vaccin Immunother 8:1485-91. 2012
    ....
  12. doi Lung transplantation in children and young adults: a 20-year single-centre experience
    Saskia Gruber
    Dept of Pediatrics and Adolescent Medicine, Medical University of Vienna, Waehringer Guertel 18 20, 1090 Vienna, Austria
    Eur Respir J 40:462-9. 2012
    ..A high rate of successful re-transplantation prolonged total patient survival...
  13. ncbi Immunoglobulin e-mediated allergies in lung-transplanted adults
    Saskia Gruber
    Department of Pediatrics and Adolescent Medicine, Medical University of Vienna, Vienna, Austria
    Transplantation 84:275-9. 2007
    ..Interestingly, type 1 allergy has not been described in transplanted adults, suggesting a particular propensity in childhood...
  14. doi IgE cross-reactivity between the major peanut allergen Ara h 2 and the nonhomologous allergens Ara h 1 and Ara h 3
    Merima Bublin
    Department of Pathophysiology and Allergy Research, Medical University of Vienna, Vienna, Austria
    J Allergy Clin Immunol 132:118-24. 2013
    ..Ara h 2 is an important predictor of clinical reactivity to peanut, but cosensitization to all 3 allergens is correlated with the severity of patients' symptoms...
  15. pmc Fc-epsilon-RI, the high affinity IgE-receptor, is robustly expressed in the upper gastrointestinal tract and modulated by mucosal inflammation
    Christina Bannert
    Department of Paediatrics and Adolescent Medicine, Medical University of Vienna, Vienna, Austria
    PLoS ONE 7:e42066. 2012
    ..Currently, a detailed characterization of FcεRI expression throughout the human gut is lacking. The aim of this study was to define the expression pattern of FcεRI in the GI tract...
  16. pmc Cord blood derived CD4+ CD25(high) T cells become functional regulatory T cells upon antigen encounter
    Elisabeth Mayer
    Department of Pediatrics and Adolescent Medicine, Medical University of Vienna, Vienna, Austria
    PLoS ONE 7:e29355. 2012
    ..To date it remains unclear whether these "excessive" responses relate to different regulatory properties of the putative T regulatory cell (Treg) compartment or even expansion of the Treg compartment itself...
  17. doi Prebiotic oligosaccharides: in vitro evidence for gastrointestinal epithelial transfer and immunomodulatory properties
    Thomas Eiwegger
    Department of Pediatrics, Medical University of Vienna, Vienna, Austria
    Pediatr Allergy Immunol 21:1179-88. 2010
    ..Moreover, there is in vitro evidence for epithelial transport of prebiotic oligosaccharides...
  18. ncbi Heat- and formalin-inactivated probiotic bacteria induce comparable cytokine patterns in intestinal epithelial cell-leucocyte cocultures
    Eleonora Dehlink
    Department of Pediatrics and Adolescent Medicine, Medical University of Vienna, Waehringer Guertel 18 20, 1090 Vienna, Austria
    J Food Prot 70:2417-21. 2007
    ....
  19. doi Cysteinyl-leukotrienes in nasal lavage fluid in children with asthma
    Florian Singer
    Department of Paediatric Surgery, Donauspital, Vienna, Austria
    Pediatr Allergy Immunol 19:227-32. 2008
    ..40). Concentration of cys-LT in NLF and exhaled NO was positively correlated (r = 0.85; p < 0.001). In conclusion, concentration of cys-LT in NLF correlates with asthma severity in children and is related to lower airway inflammation...