Thomas Sycha

Summary

Affiliation: Medical University of Vienna
Country: Austria

Publications

  1. ncbi request reprint A lack of antinociceptive or antiinflammatory effect of botulinum toxin A in an inflammatory human pain model
    Thomas Sycha
    Department of Neurology, Medical University of Vienna, Vienna, Austria
    Anesth Analg 102:509-16. 2006
  2. ncbi request reprint Rofecoxib attenuates both primary and secondary inflammatory hyperalgesia: a randomized, double blinded, placebo controlled crossover trial in the UV-B pain model
    Thomas Sycha
    Department of Neurology, Medical University of Vienna, Währinger Gürtel 18 20 A 1090 Vienna, Austria
    Pain 113:316-22. 2005
  3. ncbi request reprint UV-B irradiation attenuates dermal effects of botulinum toxin A: a randomized, double-blind, placebo-controlled study
    Thomas Sycha
    Department of Neurology, Medical University of Vienna, Vienna, Austria
    Dermatol Surg 33:S92-6. 2007
  4. ncbi request reprint The effects of remifentanil and gabapentin on hyperalgesia in a new extended inflammatory skin pain model in healthy volunteers
    Burkhard Gustorff
    Department of Anesthesia and General Intensive Care Medicine B, University of Vienna, Vienna, Austria
    Anesth Analg 98:401-7, table of contents. 2004
  5. doi request reprint Respective potencies of Botox and Dysport in a human skin model: a randomized, double-blind study
    Gottfried Kranz
    Department of Neurology, Medical University of Vienna, Wien, Austria
    Mov Disord 24:231-6. 2009
  6. ncbi request reprint Pain sensation during intradermal injections of three different botulinum toxin preparations in different doses and dilutions
    Gottfried Kranz
    Department of Neurology, Division of Neurorehabilitation, Medical University of Vienna, Vienna, Austria
    Dermatol Surg 32:886-90. 2006
  7. ncbi request reprint Effect of information on reported adverse events in a placebo-controlled trial
    Michael Ossege
    Department of Clinical Pharmacology, Medical University of Vienna, Vienna, Austria
    Drug Saf 28:81-7. 2005
  8. doi request reprint Diode laser hair removal does not interfere with botulinum toxin A treatment against axillary hyperhidrosis
    Anna Paul
    Department of Neurology, Medical University of Vienna, A 1090 Vienna, Austria
    Lasers Surg Med 42:211-4. 2010
  9. doi request reprint Antipsychotics for acute and chronic pain in adults
    Stefan Seidel
    Department of Neurology, Medical University of Vienna, Währinger Straße 13a, Vienna, Austria
    Cochrane Database Syst Rev 8:CD004844. 2013
  10. doi request reprint Antipsychotics for acute and chronic pain in adults
    Stefan Seidel
    Department of Neurology, Medical University of Vienna, Vienna, Austria
    J Pain Symptom Manage 39:768-78. 2010

Detail Information

Publications17

  1. ncbi request reprint A lack of antinociceptive or antiinflammatory effect of botulinum toxin A in an inflammatory human pain model
    Thomas Sycha
    Department of Neurology, Medical University of Vienna, Vienna, Austria
    Anesth Analg 102:509-16. 2006
    ..Furthermore, despite highly promising data from animal research, we have not observed antiinflammatory or antinociceptive effects of BoNT/A in human inflammatory pain...
  2. ncbi request reprint Rofecoxib attenuates both primary and secondary inflammatory hyperalgesia: a randomized, double blinded, placebo controlled crossover trial in the UV-B pain model
    Thomas Sycha
    Department of Neurology, Medical University of Vienna, Währinger Gürtel 18 20 A 1090 Vienna, Austria
    Pain 113:316-22. 2005
    ..We confirm that the effect of single oral dose of rofecoxib plateaus at 50 mg...
  3. ncbi request reprint UV-B irradiation attenuates dermal effects of botulinum toxin A: a randomized, double-blind, placebo-controlled study
    Thomas Sycha
    Department of Neurology, Medical University of Vienna, Vienna, Austria
    Dermatol Surg 33:S92-6. 2007
    ..Botulinum toxin type A (BoNT/A) is frequently used for cosmetic indications and hyperhidrosis...
  4. ncbi request reprint The effects of remifentanil and gabapentin on hyperalgesia in a new extended inflammatory skin pain model in healthy volunteers
    Burkhard Gustorff
    Department of Anesthesia and General Intensive Care Medicine B, University of Vienna, Vienna, Austria
    Anesth Analg 98:401-7, table of contents. 2004
    ..IMPLICATIONS: Opioid analgesia was reliably demonstrated in a new inflammatory model of primary and secondary hyperalgesia. Gabapentin showed no antihyperalgesic and no opioid-enhancing effect in this model...
  5. doi request reprint Respective potencies of Botox and Dysport in a human skin model: a randomized, double-blind study
    Gottfried Kranz
    Department of Neurology, Medical University of Vienna, Wien, Austria
    Mov Disord 24:231-6. 2009
    ..1-1.5 and 1:1.4-1.8 95% confidence intervals). The diffusion characteristics of both products were similar. A dose equivalence factor of more than 1:2 (BOT:DYS) is not supported by these objective and reproducible data...
  6. ncbi request reprint Pain sensation during intradermal injections of three different botulinum toxin preparations in different doses and dilutions
    Gottfried Kranz
    Department of Neurology, Division of Neurorehabilitation, Medical University of Vienna, Vienna, Austria
    Dermatol Surg 32:886-90. 2006
    ..Pain sensation associated with injections of botulinum neurotoxin (BoNT) is commonly reported. To date differences in pain sensation between the commercially available products containing BoNT have not been quantified...
  7. ncbi request reprint Effect of information on reported adverse events in a placebo-controlled trial
    Michael Ossege
    Department of Clinical Pharmacology, Medical University of Vienna, Vienna, Austria
    Drug Saf 28:81-7. 2005
    ..We hypothesised that information about the likelihood of receiving placebo might influence the perception of adverse effects in volunteers participating in a clinical trial...
  8. doi request reprint Diode laser hair removal does not interfere with botulinum toxin A treatment against axillary hyperhidrosis
    Anna Paul
    Department of Neurology, Medical University of Vienna, A 1090 Vienna, Austria
    Lasers Surg Med 42:211-4. 2010
    ..In order to examine this potential interference, we assessed the effect of BoNT/A on axillary hyperhidrosis with and without concomitant diode laser axillary hair removal...
  9. doi request reprint Antipsychotics for acute and chronic pain in adults
    Stefan Seidel
    Department of Neurology, Medical University of Vienna, Währinger Straße 13a, Vienna, Austria
    Cochrane Database Syst Rev 8:CD004844. 2013
    ..With atypical antipsychotics, a new class of antipsychotics, both fewer extrapyramidal side effects and additional benefits may be available...
  10. doi request reprint Antipsychotics for acute and chronic pain in adults
    Stefan Seidel
    Department of Neurology, Medical University of Vienna, Vienna, Austria
    J Pain Symptom Manage 39:768-78. 2010
    ..g., chronic headache, fibromyalgia, and painful diabetic neuropathy). With atypical antipsychotics, a new class of antipsychotics, with fewer extrapyramidal side effects and additional benefits, may be available...
  11. doi request reprint [Mirror therapy for phantom limb pain--a systematic review]
    Stefan Seidel
    Universitätsklinik für Neurologie, Medizinische Universität Wien, Wien, Austria
    Wien Klin Wochenschr 121:440-4. 2009
    ..The aim of this review was to evaluate the evidence for the treatment of phantom limb pain with mirror therapy...
  12. ncbi request reprint WITHDRAWN: Interventions for normal tension glaucoma
    Thomas Sycha
    Department of Neurology, Medical University of Vienna, , Vienna, Austria, A 1090
    Cochrane Database Syst Rev 2:CD002222. 2010
    ..Studies that focussed on reduction of intraocular pressure or haemodynamic variables are not necessarily relevant for the outcome in people with normal tension glaucoma...
  13. ncbi request reprint Interventions for preventing posterior capsule opacification
    Oliver Findl
    Department of Ophthalmology, Hanusch Hospital, Heinrich Collin Strasse 30, Vienna, Austria, A 1140
    Cochrane Database Syst Rev 2:CD003738. 2010
    ..There is no clear difference between optic materials. The choice of postoperative anti-inflammatory treatment does not seem to influence PCO development...
  14. ncbi request reprint Clopidogrel-induced platelet inhibition cannot be detected by the platelet function analyzer-100 system in stroke patients
    Nicole Kotzailias
    Department of Neurology, Medical University Vienna, Austria
    J Stroke Cerebrovasc Dis 16:199-202. 2007
    ..71; P < .002 for CEPI-CT, r = .54; P < .04 for CADP-CT). Our data indicate that the current PFA-100 cartridges are not sufficiently sensitive to detect clopidogrel-induced platelet inhibition in stroke patients...
  15. doi request reprint The pattern and time course of somatosensory changes in the human UVB sunburn model reveal the presence of peripheral and central sensitization
    Burkhard Gustorff
    Vienna Human Pain Research Group, Department of Anaesthesia, General Intensive Care Medicine and Pain Control, Medical University of Vienna, Wahringer Gurtel 18 20, 1090 Vienna, Austria
    Pain 154:586-97. 2013
    ....
  16. ncbi request reprint The sunburn pain model: the stability of primary and secondary hyperalgesia over 10 hours in a crossover setting
    Burkhard Gustorff
    Department of Anesthesia and General Intensive Care Medicine B, University of Vienna, Wahringer Gurtel 18 20, A 1090 Vienna, Austria
    Anesth Analg 98:173-7, table of contents. 2004
    ..IMPLICATIONS: The sunburn pain model provides a long time course of stable hyperalgesia with a high within-day stability and between-day repeatability for primary and secondary hyperalgesia...
  17. pmc A simple pain model for the evaluation of analgesic effects of NSAIDs in healthy subjects
    Thomas Sycha
    Department of Clinical Pharmacology, Institute of Medical Physics, Vienna University School of Medicine, Wahringer Gurtel 18 20, 1090 Vienna, Austria
    Br J Clin Pharmacol 56:165-72. 2003
    ..We evaluated an experimental pain model for NSAIDs, that included an inflammatory component to mimic clinical inflammatory pain conditions...