Sebastian F Schoppmann

Summary

Affiliation: Medical University of Vienna
Country: Austria

Publications

  1. ncbi Modern GERD treatment: feasibility of minimally invasive esophageal sphincter augmentation
    Katrin Schwameis
    Department of Surgery, Medical University of Vienna, Wahringer Gurtel 18 20, 1090 Vienna, Austria
    Anticancer Res 34:2341-8. 2014
  2. ncbi The implementation of minimally-invasive esophagectomy does not impact short-term outcome in a high-volume center
    Katrin Schwameis
    Medical University of Vienna, Department of Surgery, Upper GI Research, Comprehensive Cancer Center, Vienna, CCC GET, University Clinic of Surgery, Medical University of Vienna, Wahringer Gurtel 18 20, 1090 Vienna, Austria
    Anticancer Res 33:2085-91. 2013
  3. doi Amplification but not translocation of anaplastic lymphoma kinase is a frequent event in oesophageal cancer
    Sebastian F Schoppmann
    Department of Surgery, Upper GI Research Unit, Medical University of Vienna, Austria
    Eur J Cancer 49:1876-81. 2013
  4. doi Podoplanin expressing cancer associated fibroblasts are associated with unfavourable prognosis in adenocarcinoma of the esophagus
    Sebastian F Schoppmann
    Department of Surgery and Comprehensive Cancer Center Vienna, Medical University of Vienna General Hospital, Waehringer Guertel 18 20, 1090 Vienna, Austria
    Clin Exp Metastasis 30:441-6. 2013
  5. doi Lymphangiogenesis and lymphovascular invasion diminishes prognosis in esophageal cancer
    Sebastian F Schoppmann
    Department of Surgery, Upper GI Research Unit, Medical University of Vienna, Cancer Comprehensive Center Vienna GET, Vienna, Austria
    Surgery 153:526-34. 2013
  6. ncbi Brain metastases of gastro-oesophageal cancer: evaluation of molecules with relevance for targeted therapies
    Matthias Preusser
    Medical University of Vienna, Department of Surgery, Waehringer Guertel 18 20, 1090 Vienna, Austria
    Anticancer Res 33:1065-71. 2013
  7. doi Outcome and complications of long-term self-expanding esophageal stenting
    S F Schoppmann
    Department of Surgery, Upper GI Research, Medical University of Vienna, Vienna, Austria
    Dis Esophagus 26:154-8. 2013
  8. doi Expression of podoplanin is a rare event in sporadic gastrointestinal stromal tumors and does not influence prognosis
    Sebastian F Schoppmann
    Department of Surgery, Upper GI Research Unit, Medical University of Vienna, General Hospital, Waehringer Guertel 18 20, A 1090 Vienna, Austria
    Future Oncol 8:859-66. 2012
  9. doi Podoplanin-expressing cancer-associated fibroblasts are associated with poor prognosis in invasive breast cancer
    Sebastian F Schoppmann
    Department of Surgery, General Hospital, Medical University of Vienna, Waehringer Guertel 18 20, 1090, Vienna, Austria
    Breast Cancer Res Treat 134:237-44. 2012
  10. doi Phosphorylation of signal transducer and activator of transcription 3 (STAT3) correlates with Her-2 status, carbonic anhydrase 9 expression and prognosis in esophageal cancer
    Sebastian F Schoppmann
    Department of Surgery, Cancer Comprehensive Center Vienna, University of Vienna, Waehringer Guertel 18 20, 1090, Vienna, Austria
    Clin Exp Metastasis 29:615-24. 2012

Collaborators

Detail Information

Publications59

  1. ncbi Modern GERD treatment: feasibility of minimally invasive esophageal sphincter augmentation
    Katrin Schwameis
    Department of Surgery, Medical University of Vienna, Wahringer Gurtel 18 20, 1090 Vienna, Austria
    Anticancer Res 34:2341-8. 2014
    ..Novel laparoscopic magnetic sphincter augmentation for GERD was evaluated prospectively...
  2. ncbi The implementation of minimally-invasive esophagectomy does not impact short-term outcome in a high-volume center
    Katrin Schwameis
    Medical University of Vienna, Department of Surgery, Upper GI Research, Comprehensive Cancer Center, Vienna, CCC GET, University Clinic of Surgery, Medical University of Vienna, Wahringer Gurtel 18 20, 1090 Vienna, Austria
    Anticancer Res 33:2085-91. 2013
    ..Minimally-invasive surgical techniques introduced to the surgical treatment of esophageal malignancies have been shown to successfully diminish surgical trauma and postoperative morbidity...
  3. doi Amplification but not translocation of anaplastic lymphoma kinase is a frequent event in oesophageal cancer
    Sebastian F Schoppmann
    Department of Surgery, Upper GI Research Unit, Medical University of Vienna, Austria
    Eur J Cancer 49:1876-81. 2013
    ..These fusion-proteins are potential pharmaceutically targets. Aim of this study was to investigate ALK gene status in a large cohort of squamous cell carcinoma (SCC) and adenocarcinoma (AC) of the oesophagus...
  4. doi Podoplanin expressing cancer associated fibroblasts are associated with unfavourable prognosis in adenocarcinoma of the esophagus
    Sebastian F Schoppmann
    Department of Surgery and Comprehensive Cancer Center Vienna, Medical University of Vienna General Hospital, Waehringer Guertel 18 20, 1090 Vienna, Austria
    Clin Exp Metastasis 30:441-6. 2013
    ..In around 20 % of patients with esophagal AC, podoplanin expressing CAFs are evident, defining a high risk subgroup. In these patients, podoplanin expressing CAFs might represent new therapeutical targets...
  5. doi Lymphangiogenesis and lymphovascular invasion diminishes prognosis in esophageal cancer
    Sebastian F Schoppmann
    Department of Surgery, Upper GI Research Unit, Medical University of Vienna, Cancer Comprehensive Center Vienna GET, Vienna, Austria
    Surgery 153:526-34. 2013
    ..The aim of this study was to evaluate the clinical role of lymphangiogenesis and LVI in a large cohort of esophageal cancer...
  6. ncbi Brain metastases of gastro-oesophageal cancer: evaluation of molecules with relevance for targeted therapies
    Matthias Preusser
    Medical University of Vienna, Department of Surgery, Waehringer Guertel 18 20, 1090 Vienna, Austria
    Anticancer Res 33:1065-71. 2013
    ..Brain metastases (BM) of gastro-oesophageal cancer are exceedingly rare and only limited data exist on their pathobiology...
  7. doi Outcome and complications of long-term self-expanding esophageal stenting
    S F Schoppmann
    Department of Surgery, Upper GI Research, Medical University of Vienna, Vienna, Austria
    Dis Esophagus 26:154-8. 2013
    ..No stent-related death was observed. Our data provide evidence that long-period esophageal stenting is safe and effective for various indications...
  8. doi Expression of podoplanin is a rare event in sporadic gastrointestinal stromal tumors and does not influence prognosis
    Sebastian F Schoppmann
    Department of Surgery, Upper GI Research Unit, Medical University of Vienna, General Hospital, Waehringer Guertel 18 20, A 1090 Vienna, Austria
    Future Oncol 8:859-66. 2012
    ..We investigated podoplanin expression and its clinical relevance in a large series of sporadic GISTs...
  9. doi Podoplanin-expressing cancer-associated fibroblasts are associated with poor prognosis in invasive breast cancer
    Sebastian F Schoppmann
    Department of Surgery, General Hospital, Medical University of Vienna, Waehringer Guertel 18 20, 1090, Vienna, Austria
    Breast Cancer Res Treat 134:237-44. 2012
    ..Podoplanin-expressing CAFs contribute to the prognosis of invasive breast cancer, indicating a highly aggressive subgroup. CAFs may present a highly selective target for anti-cancer therapies in patients with invasive breast cancer...
  10. doi Phosphorylation of signal transducer and activator of transcription 3 (STAT3) correlates with Her-2 status, carbonic anhydrase 9 expression and prognosis in esophageal cancer
    Sebastian F Schoppmann
    Department of Surgery, Cancer Comprehensive Center Vienna, University of Vienna, Waehringer Guertel 18 20, 1090, Vienna, Austria
    Clin Exp Metastasis 29:615-24. 2012
    ..pSTAT3 plays an important role in the development of AC. Expression of pSTAT3 correlates with Her-2 status and CAIX expression and is associated with tumor progression and worse outcome, offering expectantly therapeutical implications...
  11. doi HER2/neu expression correlates with vascular endothelial growth factor-C and lymphangiogenesis in lymph node-positive breast cancer
    S F Schoppmann
    Department of Surgery, Medical University of Vienna, Vienna, Austria
    Ann Oncol 21:955-60. 2010
    ..In addition to blocking of HER2/neu, tyrosine kinase significantly decreased VEGF-C expression in vitro...
  12. ncbi Open versus minimally invasive esophagectomy: a single-center case controlled study
    Sebastian F Schoppmann
    Department of Surgery, Medical University of Vienna, Waehringer Guertel 18 20, 1090, Vienna, Austria
    Surg Endosc 24:3044-53. 2010
    ..Although technically complex, recent case studies showed that minimally invasive approaches to esophagectomy are feasible and have the potential to improve mortality, hospital stay, and functional outcome...
  13. doi Expression of Her-2 in carcinomas of the esophagus
    Sebastian F Schoppmann
    Department of Surgery, Medical University of Vienna, Waehringer Guertel 18 20, 1090, Vienna, Austria
    Am J Surg Pathol 34:1868-73. 2010
    ..Although Her-2-overexpression in esophageal cancer seems to have no influence on patients' survival, these subtypes of esophageal ACs have to be considered as targets for an anti-Her-2 therapy...
  14. doi HER-2 status in primary oesophageal cancer, lymph nodes and distant metastases
    S F Schoppmann
    Department of Surgery, Medical University of Vienna, Vienna, Austria
    Br J Surg 98:1408-13. 2011
    ..This approach is based on primary tumour characteristics, without knowledge of expression patterns at metastatic sites. In oesophageal cancer, concordance between HER-2 status at the primary tumour and other sites is unknown...
  15. ncbi Fifty-five minimally invasive Esophagectomies: a single centre experience
    Sebastian F Schoppmann
    Department of Surgery, Medical University of Vienna, A 1090 Vienna, Austria
    Anticancer Res 29:2719-25. 2009
    ..Minimally invasive esophagectomy is an evolving alternative to the open technique with the goal of providing efficient oncological therapy while minimizing morbidity by diminishing surgical trauma...
  16. ncbi VEGF-C expressing tumor-associated macrophages in lymph node positive breast cancer: impact on lymphangiogenesis and survival
    Sebastian F Schoppmann
    Department of Surgery, University of Vienna, Austria
    Surgery 139:839-46. 2006
    ..Aim of this study was to clear the role of VEGF-C/D expressing TAMs in invasive breast cancer...
  17. ncbi Hypoxia inducible factor-1alpha correlates with VEGF-C expression and lymphangiogenesis in breast cancer
    Sebastian F Schoppmann
    Department of Surgery, University of Vienna, Waehringer, Vienna, Austria
    Breast Cancer Res Treat 99:135-41. 2006
    ....
  18. ncbi Lymphangiogenesis, inflammation and metastasis
    Sebastian F Schoppmann
    Department of Surgery, Medical University of Vienna, Waehringer Guertel 18 20, A 1090 Vienna, Austria
    Anticancer Res 25:4503-11. 2005
    ..In the framework of possible antilymphangiogenic therapies, this review focuses on the mechanisms of lymphangiogenesis in general, and especially on the role of lymphatic vessels in the process of metastasis...
  19. ncbi Comparison between DCF (Docetaxel, Cisplatin and 5-Fluorouracil) and modified EOX (Epirubicin, Oxaliplatin and Capecitabine) as palliative first-line chemotherapy for adenocarcinoma of the upper gastrointestinal tract
    Aysegül Ilhan-Mutlu
    Department of Medicine I, Division of Oncology, Comprehensive Cancer Center Vienna, Medical University of Vienna, Waehringer Guertel 18 20, A 1090 Vienna, Austria
    Anticancer Res 33:3455-9. 2013
    ..In this analysis, we compare DCF and EOX regarding toxicity and efficacy...
  20. ncbi Overexpression of Id-1 is associated with poor clinical outcome in node negative breast cancer
    Sebastian F Schoppmann
    Department of Surgery, University of Vienna, Vienna, Austria
    Int J Cancer 104:677-82. 2003
    ..Our results also suggest that due to the apparent interaction of Id-1 with the steroid-receptor system in breast cancer, hormonal therapies might influence Id-1 expression and its impact on clinical outcome...
  21. ncbi Modified EOX (Epirubicin, Oxaliplatin and Capecitabine) as palliative first-line chemotherapy for gastroesophageal adenocarcinoma
    Ursula Pluschnig
    Department of Medicine I, Division of Oncology, Comprehensive Cancer Center Vienna, Medical University of Vienna, Waehringer Guertel 18 20, A 1090 Vienna, Austria
    Anticancer Res 33:1035-9. 2013
    ..Therefore, we aimed to establish a modified version of the EOX regimen with improved tolerability for these patients...
  22. pmc Prognostic value of lymphangiogenesis and lymphovascular invasion in invasive breast cancer
    Sebastian F Schoppmann
    Department of Surgery, Medical University of Vienna, Austria
    Ann Surg 240:306-12. 2004
    ..The aim of this study was to investigate the prognostic relevance of lymphangiogenesis and lymphovascular invasion in a large cohort of breast cancer patients...
  23. doi Carbonic anhydrase IX overexpression is associated with diminished prognosis in esophageal cancer and correlates with Her-2 expression
    Peter Birner
    Institute of Pathology, Medical University of Vienna, Vienna, Austria
    Ann Surg Oncol 18:3330-7. 2011
    ..This study was designed to investigate the clinical role of CAIX and its association with Her-2 in a large cohort of adeno- (AC) and squamous cell carcinomas (SCC) of the esophagus and their metastases...
  24. doi Downregulation of phosphatidylethanolamine binding protein 1 associates with clinical risk factors in gastrointestinal stromal tumors, but not with activation of the RAF-1-MEK-ETV1 pathway
    Sebastian F Schoppmann
    Department of Surgery, Medical University of Vienna, Austria
    Cancer Lett 335:26-30. 2013
    ..Loss of PEBP1 associates with clinical risk factors, but since no significant influence on survival was found, further studies are required...
  25. doi Human homologue for Caenorhabditis elegans CUL-4 protein overexpression is associated with malignant potential of epithelial ovarian tumours and poor outcome in carcinoma
    Peter Birner
    Clinical Institute of Pathology, Medical University of Vienna, Vienna, Austria
    J Clin Pathol 65:507-11. 2012
    ..However, the role of CUL-4 in human carcinomas is widely unknown...
  26. pmc Discrimination between circulating endothelial cells and blood cell populations with overlapping phenotype reveals distinct regulation and predictive potential in cancer therapy
    Patrick Starlinger
    Department of Surgery, Medical University of Vienna, General Hospital, Waehringer Guertel 18 20, Vienna, Austria
    Neoplasia 13:980-90. 2011
    ....
  27. ncbi Overexpression of hypoxia-inducible factor 1alpha is associated with an unfavorable prognosis in lymph node-positive breast cancer
    Monika Schindl
    Institute of Clinical Pathology, Department of Surgery, University of Vienna Medical School, Wahringer Gurtel 18 20, A 1090 Vienna, Austria
    Clin Cancer Res 8:1831-7. 2002
    ..The aim of this study was to determine the prognostic influence of HIF-1alpha expression in patients with advanced-stage breast cancer, evident by positive lymph nodes...
  28. ncbi Expression of BRAF V600E mutant protein in epithelial ovarian tumors
    Matthias Preusser
    Department of Medicine I, Medical University of Vienna, Vienna, Austria
    Appl Immunohistochem Mol Morphol 21:159-64. 2013
    ..The aim of this study was to investigate the expression of BRAF V600E aberrant protein using a novel mutation-specific antibody in epithelial ovarian tumors...
  29. doi Temporary placement of self-expanding oesophageal stents as bridging for neo-adjuvant therapy
    Felix B Langer
    Department of Surgery, Division of General Surgery, Medical University of Vienna, General Hospital Vienna, Vienna, Austria
    Ann Surg Oncol 17:470-5. 2010
    ..The aim of this analysis was to assess the efficacy of temporary stent placement for dysphagia relief during neo-adjuvant treatment for locally advanced disease...
  30. ncbi Review on novel concepts of columnar lined esophagus
    Johannes Lenglinger
    Manometry Lab and Upper GI Service, Department of Surgery, University Clinic of Surgery, CCC GET, Medical University of Vienna, Vienna General Hospital, Wahringer Gurtel 18 20, 1090, Vienna, Austria
    Wien Klin Wochenschr 125:577-90. 2013
    ..Columnar lined esophagus (CLE) is a marker for gastroesophageal reflux and associates with an increased cancer risk among those with Barrett's esophagus. Recent studies fostered the development of integrated CLE concepts...
  31. ncbi A phase II trial of two durations of Bevacizumab added to neoadjuvant gemcitabine for borderline and locally advanced pancreatic cancer
    Klaus Sahora
    MD FACS, Department of Surgery and Comprehensive Cancer Center Medical University of Vienna, Waehringer Guertel 18 20, 1090 Vienna, Austria
    Anticancer Res 34:2377-84. 2014
    ..We report the results of a phase II trial of adding the anti-ascular endothelial growth factor (VEGF) bevacizumab to gemcitabine neoadjuvant chemotherapy for patients with borderline and unresectable non-metastatic pancreatic cancer...
  32. ncbi Comparison of lymphangiogenesis between primary colorectal cancer and corresponding liver metastases
    Alexandra Schoppmann
    Department of Anesthesiology, Medical University of Vienna, Vienna, Austria
    Anticancer Res 31:4605-11. 2011
    ..In the current study, we investigated the clinical impact of the lymphangiogenic activity in CRCs and their corresponding LMs...
  33. ncbi Overexpression of the human homologue for Caenorhabditis elegans cul-4 gene is associated with poor outcome in node-negative breast cancer
    Monika Schindl
    Clinical Institute of Pathology, Medical University of Vienna, Vienna, Austria
    Anticancer Res 27:949-52. 2007
    ..The aim of this study was to investigate the expression and prognostic relevance of CUL-4 protein in lymph node-negative breast cancer, one of the most common malignancies worldwide...
  34. ncbi Review on the annual cancer risk of Barrett's esophagus in persons with symptoms of gastroesophageal reflux disease
    Johannes Lenglinger
    University Clinic of Surgery, Comprehensive Cancer Center Vienna Medical University Vienna, Vienna General Hospital, Wahringer Gurtel 18 20, A 1090 Vienna, Austria
    Anticancer Res 32:5465-73. 2012
    ..We aimed to examine the reported annual cancer risk for NDBE in persons with symptoms of gastroesophageal reflux disease, i.e. symptomatic NDBE...
  35. doi ALK gene translocations and amplifications in brain metastases of non-small cell lung cancer
    Matthias Preusser
    Department of Medicine I, Medical University of Vienna, Austria
    Lung Cancer 80:278-83. 2013
    ..Increased incidence of brain metastases (BM) in non-small cell lung cancer (NSCLC) with ALK translocations was postulated, however, ALK gene aberrations in NSCLC-BM have not been investigated so far...
  36. doi Gastrointestinal stromal tumors: diagnosis, therapy and follow-up care in Austria
    Evelyne Bareck
    Department of Surgery, General Hospital, Wiener Neustadt, Vienna, Austria
    Wien Med Wochenschr 163:137-52. 2013
    ..This paper contains guidelines and recommendations for diagnosis, therapy, and follow-up of GIST patients in Austria...
  37. ncbi Level of Id-1 protein expression correlates with poor differentiation, enhanced malignant potential, and more aggressive clinical behavior of epithelial ovarian tumors
    Monika Schindl
    Institute of Clinical Pathology, University of Vienna, A 1090 Vienna, Austria
    Clin Cancer Res 9:779-85. 2003
    ..Aim of this study was to investigate Id-1 protein expression in epithelial ovarian tumors and its clinical relevance in ovarian cancer...
  38. pmc Platelet-stored angiogenesis factors: clinical monitoring is prone to artifacts
    Patrick Starlinger
    Department of Surgery, General Hospital, Medical University of Vienna, Austria
    Dis Markers 31:55-65. 2011
    ..Since mediators of angiogenesis are stored in platelets, their measurement in plasma is sensitive to inadvertent platelet activation during blood processing...
  39. ncbi Influence of resection extent on morbidity in surgery for squamous cell cancer at the pharyngoesophageal junction
    Peter Panhofer
    Department of General Surgery, University Clinic of Surgery, Medical University of Vienna, Wahringer Gurtel 18 20, Vienna, Austria
    Langenbecks Arch Surg 398:221-30. 2013
    ..Limited surgical procedures have been adopted as well. The aim of this retrospective study was to evaluate whether the extent of resection influences postoperative safety and mortality...
  40. ncbi Docetaxel, cisplatin and 5-fluorouracil plus granulocyte colony-stimulating factor prophylaxis in patients with metastatic adenocarcinoma of the stomach and gastroesophageal junction: experience at the Medical University of Vienna
    Marija Bojic
    General Hospital Vienna, Medical University of Vienna, Department of Internal Medicine I, Division of Oncology, Waehringer Guertel 18 20, A 1090 Vienna, Austria
    Anticancer Res 31:2379-82. 2011
    ....
  41. doi Solving the problem of difficult stent removal due to tissue ingrowth in partially uncovered esophageal self-expanding metal stents
    Felix B Langer
    Upper Gastrointestinal Service, University Clinic of Surgery, Medical University of Vienna, Vienna, Austria
    Ann Thorac Surg 89:1691-2. 2010
    ..By adopting this procedure to scheduled stent removals, partially uncovered SEMS may be used to prevent the frequently observed migrations of fully-covered stents in the treatment of esophageal perforation or anastomotic leakage...
  42. doi RAF-kinase inhibitor protein (RKIP) downregulation in esophageal cancer and its metastases
    Peter Birner
    Institute of Pathology, Medical University of Vienna, Waehringer Guertel 18 20, 1090, Vienna, Austria
    Clin Exp Metastasis 29:551-9. 2012
    ..Inhibition of RKIP-downregulation might reduce the ability of esophageal cancers to establish disseminated disease...
  43. ncbi The value of protecting the longitudinal staple line with invaginating sutures during esophageal reconstruction by gastric tube pull-up
    Gerd R Silberhumer
    Department of General Surgery, University Clinic of Surgery, Medical University of Vienna, AT 1090 Vienna, Austria
    Dig Surg 26:337-41. 2009
    ..Rupture of the gastric tube staple line is a rare but serious surgical complication. One unresolved issue is whether oversewing of the longitudinal gastric staple line is necessary to avoid staple line rupture or insufficiency...
  44. ncbi Novel clinically relevant genes in gastrointestinal stromal tumors identified by exome sequencing
    Sebastian F Schoppmann
    Authors Affiliations Department of Surgery Center for Medical Statistics, Informatics, and Intelligent Systems Department of Obstetrics and Gynecology and Core Unit Next Generation Sequencing Clinical Institute of Pathology, Medical University of Vienna and Center for Integrative Bioinformatics Vienna CIBIV, Max F Perutz Laboratories, University of Vienna and Medical University of Vienna, and Faculty of Computer Science, University of Vienna, Vienna, Austria
    Clin Cancer Res 19:5329-39. 2013
    ..Chromosomal gains and losses resulting in altered gene dosage are known to be recurrent in gastrointestinal stromal tumors (GIST). The aim of our study was the identification of clinical relevant genes in these candidate regions...
  45. ncbi The cardia: esophageal or gastric? Critical reviewing the anatomy and histopathology of the esophagogastric junction
    Johannes Lenglinger
    Department of Surgery, Medical University Vienna, Vienna
    Acta Chir Iugosl 59:15-26. 2012
    ..Discrepancy exists regarding the anatomical allocation of the cardia: esophageal or gastric. With this review we aimed to clarify this issue...
  46. ncbi Overexpression of CMET is associated with signal transducer and activator of transcription 3 activation and diminished prognosis in oesophageal adenocarcinoma but not in squamous cell carcinoma
    Ildiko Mesteri
    Department of Pathology, Medical University of Vienna, A 1090 Vienna, Austria Comprehensive Cancer Center Vienna Gastroesophageal Cancers Unit CCC GET, Medical University of Vienna, A 1090 Vienna, Austria
    Eur J Cancer 50:1354-60. 2014
    ..Inhibition of cMet is a promising therapeutic approach in human cancer, but few data in oesophageal cancer exist...
  47. doi MAPKAP kinase 2 overexpression influences prognosis in gastrointestinal stromal tumors and associates with copy number variations on chromosome 1 and expression of p38 MAP kinase and ETV1
    Peter Birner
    Departments of Surgery and Obstetrics and Gynecology, Clinical Institute of Pathology, Institute of Neurology, Medical University of Vienna, Vienna, Austria
    Clin Cancer Res 18:1879-87. 2012
    ..ETV1 has been proposed to be activated by KIT mutations in gastrointestinal stromal tumors (GIST). The aim of the study was to evaluate the clinical role of ETV1 and associated proteins in GIST...
  48. doi Accuracy of hydro-multidetector row CT in the local T staging of oesophageal cancer compared to postoperative histopathological results
    Ahmed Ba-Ssalamah
    Department of Radiology, Medical University of Vienna, Waehringer Guertel 18 20, 1090 Vienna, Austria
    Eur Radiol 21:2326-35. 2011
    ..To evaluate the accuracy of multidetector computed tomography with water filling (Hydro-MDCT) in the T-staging of patients with oesophageal cancer...
  49. ncbi Conversion from sleeve gastrectomy to Roux-en-Y gastric bypass--indications and outcome
    Felix B Langer
    Department of Surgery, Division of General Surgery, Medical University of Vienna, Waehringer Guertel 18 20, 1090 Vienna, Austria
    Obes Surg 20:835-40. 2010
    ..In the long-term follow-up, weight loss failure and intractable severe reflux can necessitate further surgical intervention...
  50. ncbi Lymphatic vessels and lymphangiogenesis in female cancer: mechanisms, clinical impact and possible implications for anti-lymphangiogenic therapies (Review)
    Sebastian F Schoppmann
    Institute of Clinical Pathology, University of Vienna, Vienna, Austria
    Oncol Rep 9:455-60. 2002
    ....
  51. doi HER2 gene amplification and protein expression in pancreatic ductal adenocarcinomas
    Klaus Aumayr
    Clinical Institute of Pathology Department of Surgery, Medical University of Vienna, Vienna Pathologie and Zytodiagnostik, Schweygerstraße 7a, Hall in Tirol, Austria
    Appl Immunohistochem Mol Morphol 22:146-52. 2014
    ..The purpose of this study was to evaluate HER2 gene amplification and protein expression in PDAC...
  52. doi Improved molecular classification of serrated lesions of the colon by immunohistochemical detection of BRAF V600E
    Ildiko Mesteri
    Clinical Institute of Pathology, Medical University of Vienna, Vienna, Austria
    Mod Pathol 27:135-44. 2014
    ....
  53. ncbi Telomerase-immortalized lymphatic and blood vessel endothelial cells are functionally stable and retain their lineage specificity
    Sebastian F Schoppmann
    Department of Surgery, University of Vienna, Vienna, Austria
    Microcirculation 11:261-9. 2004
    ..These subtypes are ephemeral and lose purity through passaging. To generate reproducible in vitro and in vivo experiments stable blood and lymphatic endothelial cell lines are an essential prerequisite...
  54. ncbi Heat shock treatment of tumor lysate-pulsed dendritic cells enhances their capacity to elicit antitumor T cell responses against medullary thyroid carcinoma
    Thomas Bachleitner-Hofmann
    Department of Surgery, Medical University of Vienna, Wahringer Gurtel 18 20, A 1090 Vienna, Austria
    J Clin Endocrinol Metab 91:4571-7. 2006
    ..The aim of our investigations was to evaluate whether heat shock also increases the capacity of human monocyte-derived DCs to stimulate antitumor T cell responses against MTC tumor cells...
  55. ncbi Adequate preoperative staging rarely leads to a change of intraoperative strategy in patients undergoing surgery for colorectal cancer liver metastases
    Dietmar Tamandl
    Department of Surgery, Medical University of Vienna, Vienna, Austria
    Surgery 143:648-57. 2008
    ..We investigated the value of preoperative staging on detection of additional resectable hepatic lesions in metastatic colorectal cancer patients...
  56. pmc Myelosuppression of thrombocytes and monocytes is associated with a lack of synergy between chemotherapy and anti-VEGF treatment
    Patrick Starlinger
    Department of Surgery, Medical University of Vienna, General Hospital, Vienna, Austria
    Neoplasia 13:419-27. 2011
    ..VEGF blockade was found to counteract cell mobilization. We aimed to determine why agents like gemcitabine do not elicit TEM and EPC recruitment and may therefore lack synergy with anti-VEGF therapy...
  57. ncbi Increase in podoplanin-expressing intestinal lymphatic vessels in inflammatory bowel disease
    Silvana Geleff
    Institute of Clinical Pathology, University of Vienna, Waehringer Guertel 18 20, A 1090, Vienna, Austria
    Virchows Arch 442:231-7. 2003
    ..These findings suggested that lymph-vessel proliferation in IBDs may be triggered by chronic inflammation irrespective of its organization and is maintained in fibrotic end-stage disease...
  58. ncbi Mutant IDH1 inhibits PI3K/Akt signaling in human glioma
    Peter Birner
    Department of Neuropathology, Institute of Pathology, Ruprecht Karls University Heidelberg, Heidelberg, Germany Clinical Institute of Pathology, Medical University of Vienna, Vienna, Austria
    Cancer 120:2440-7. 2014
    ..The aim of this study was to investigate a hypothetical relation between IDH1 and PI3K signaling...
  59. pmc Tumor-associated macrophages express lymphatic endothelial growth factors and are related to peritumoral lymphangiogenesis
    Sebastian F Schoppmann
    Department of Pathology, University of Vienna Allgemeines Krankenhaus, Austria
    Am J Pathol 161:947-56. 2002
    ..In conclusion VEGF-C-expressing TAMs play a novel role in peritumoral lymphangiogenesis and subsequent dissemination in human cancer...