Werner Schmid

Summary

Affiliation: Medical University of Vienna
Country: Austria

Publications

  1. doi request reprint Hypochlorite-oxidized low density lipoproteins reduce production and bioavailability of nitric oxide in RAW 264.7 macrophages by distinct mechanisms
    Werner Schmid
    Center for Physiology and Pathophysiology, Institute of Physiology, Medical University of Vienna, and Department of Urology, Rudolfstiftung Hospital, Vienna, Austria
    Life Sci 83:50-8. 2008
  2. doi request reprint Estimation of platelet function under high shear conditions to assist a rapid diagnosis of Heyde Syndrome
    Werner Schmid
    Center for Physiology and Pathophysiology, Institute of Physiology, Department of Internal Medicine III, Medical University of Vienna, Vienna 1090, Austria
    Platelets 19:636-40. 2008
  3. doi request reprint Hypochlorite-oxidized LDL induces intraplatelet ROS formation and surface exposure of CD40L--a prominent role of CD36
    Alice Assinger
    Institute of Physiology, Center for Physiology and Pharmacology, Medical University of Vienna, Schwarzspanierstr 17, A 1090 Vienna, Austria
    Atherosclerosis 213:129-34. 2010
  4. doi request reprint Specific binding of hypochlorite-oxidized HDL to platelet CD36 triggers proinflammatory and procoagulant effects
    Alice Assinger
    Institute of Physiology, Center for Physiology and Pharmacology, Medical University of Vienna, Schwarzspanierstr 17, A 1090 Vienna, Austria
    Atherosclerosis 212:153-60. 2010
  5. doi request reprint Platelet-stimulating effects of oxidized LDL are not attributable to toxic properties of the lipoproteins
    Werner Schmid
    Institute of Physiology, Center for Physiology and Pathophysiology, Medical University of Vienna, Schwarzspanierstr 17 A 1090 Vienna, Austria
    Thromb Res 122:630-9. 2008
  6. doi request reprint Decreased VASP phosphorylation in platelets of male and female smokers of young age
    Alice Assinger
    Institute of Physiology, Center for Physiology and Pharmacology, Medical University of Vienna, Schwarzspanierstr 17 A 1090 Vienna, Austria
    Platelets 21:596-603. 2010
  7. pmc Iron deficiency alters megakaryopoiesis and platelet phenotype independent of thrombopoietin
    Rayko Evstatiev
    Division of Gastroenterology and Hepatology, Department of Medicine III, Medical University of Vienna, Vienna, Austria Christian Doppler Laboratory on Molecular Cancer Chemoprevention, Medical University of Vienna, Vienna, Austria
    Am J Hematol 89:524-9. 2014
  8. doi request reprint Oxidation by hypochlorite converts protective HDL into a potent platelet agonist
    Alice Assinger
    Institute of Physiology, Center for Physiology and Pathophysiology, Medical University of Vienna, Schwarzspanierstrasse 17, Vienna, Austria
    FEBS Lett 582:778-84. 2008
  9. doi request reprint Iron deficiency generates secondary thrombocytosis and platelet activation in IBD: the randomized, controlled thromboVIT trial
    Stefanie Kulnigg-Dabsch
    Division of Gastroenterology and Hepatology, Department of Medicine III, Medical University of Vienna, Vienna, Austria
    Inflamm Bowel Dis 19:1609-16. 2013
  10. ncbi request reprint Redox-sensitive impairment of porcine coronary artery vasodilation by hypochlorite-modified LDL
    Christian A Plass
    Institute of Physiology, Center for Physiology and Pathophysiology, Medical University of Vienna, Schwarzspanierstr 17, A 1090 Vienna, Austria
    Atherosclerosis 190:330-7. 2007

Collaborators

  • Alice Assinger
  • Maria Zellner
  • Jurgen Stein
  • Hildegard Laggner
  • Ulrich Budde
  • Diethart Schmid
  • Gottfried Novacek
  • Rayko Evstatiev
  • Stefanie Kulnigg-Dabsch
  • Ivo Volf
  • Christoph Gasche
  • Christian A Plass
  • Hendrik Jan Ankersmit
  • Hans Michael Kvasnicka
  • Vineeta Khare
  • Adam Bukaty
  • Robert Eferl
  • Lidia Surman
  • Barbara Scheiber-Mojdehkar
  • Kathrin Lippert
  • Kristine Jimenez
  • Stefanie Howaldt
  • Thomas Waldhor
  • Houman Kamali
  • Oliver Mickisch
  • Ursula Kreatschitsch
  • Erik W Holy
  • Ernst Wolner
  • Georg Alexander Roth
  • Markus Brunner
  • Bernhard Moser
  • Andreas Zuckermann
  • Erika Jensen-Jarolim
  • George Boltz-Nitulescu
  • Edith Bielek
  • Christoph Buchta
  • Christiane Rosin

Detail Information

Publications12

  1. doi request reprint Hypochlorite-oxidized low density lipoproteins reduce production and bioavailability of nitric oxide in RAW 264.7 macrophages by distinct mechanisms
    Werner Schmid
    Center for Physiology and Pathophysiology, Institute of Physiology, Medical University of Vienna, and Department of Urology, Rudolfstiftung Hospital, Vienna, Austria
    Life Sci 83:50-8. 2008
    ..By mediating these effects on production and bioavailability of NO, hyp-OxLDL might also contribute to atherogenesis by reducing the antiatherogenic effects of nitric oxide...
  2. doi request reprint Estimation of platelet function under high shear conditions to assist a rapid diagnosis of Heyde Syndrome
    Werner Schmid
    Center for Physiology and Pathophysiology, Institute of Physiology, Department of Internal Medicine III, Medical University of Vienna, Vienna 1090, Austria
    Platelets 19:636-40. 2008
    ..This test offers an easy to use diagnostic tool to evaluate platelet function in suspected Heyde Syndrome thus leading to immediate tailored patient's management...
  3. doi request reprint Hypochlorite-oxidized LDL induces intraplatelet ROS formation and surface exposure of CD40L--a prominent role of CD36
    Alice Assinger
    Institute of Physiology, Center for Physiology and Pharmacology, Medical University of Vienna, Schwarzspanierstr 17, A 1090 Vienna, Austria
    Atherosclerosis 213:129-34. 2010
    ....
  4. doi request reprint Specific binding of hypochlorite-oxidized HDL to platelet CD36 triggers proinflammatory and procoagulant effects
    Alice Assinger
    Institute of Physiology, Center for Physiology and Pharmacology, Medical University of Vienna, Schwarzspanierstr 17, A 1090 Vienna, Austria
    Atherosclerosis 212:153-60. 2010
    ..Therefore it was the aim of this work to clarify if these platelet-activating effects result from specific binding of hypochlorite-oxidized HDL (hyp-OxHDL) to the platelet surface and to identify responsible receptors...
  5. doi request reprint Platelet-stimulating effects of oxidized LDL are not attributable to toxic properties of the lipoproteins
    Werner Schmid
    Institute of Physiology, Center for Physiology and Pathophysiology, Medical University of Vienna, Schwarzspanierstr 17 A 1090 Vienna, Austria
    Thromb Res 122:630-9. 2008
    ..As a conclusion, platelet-activating effects of oxidatively modified LDL are not attributable to toxic properties of the lipoproteins and this finding might expand possibilities for therapeutical intervention...
  6. doi request reprint Decreased VASP phosphorylation in platelets of male and female smokers of young age
    Alice Assinger
    Institute of Physiology, Center for Physiology and Pharmacology, Medical University of Vienna, Schwarzspanierstr 17 A 1090 Vienna, Austria
    Platelets 21:596-603. 2010
    ..Therefore, our findings add another piece of evidence to the harmful effects of smoking in both male and female smokers...
  7. pmc Iron deficiency alters megakaryopoiesis and platelet phenotype independent of thrombopoietin
    Rayko Evstatiev
    Division of Gastroenterology and Hepatology, Department of Medicine III, Medical University of Vienna, Vienna, Austria Christian Doppler Laboratory on Molecular Cancer Chemoprevention, Medical University of Vienna, Vienna, Austria
    Am J Hematol 89:524-9. 2014
    ..Iron deficiency-induced thrombocytosis may have evolved to maintain or increase the coagulation capacity in conditions with chronic bleeding...
  8. doi request reprint Oxidation by hypochlorite converts protective HDL into a potent platelet agonist
    Alice Assinger
    Institute of Physiology, Center for Physiology and Pathophysiology, Medical University of Vienna, Schwarzspanierstrasse 17, Vienna, Austria
    FEBS Lett 582:778-84. 2008
    ..The observed effects are dose dependent and can be blocked by an antibody directed against the lipoprotein-binding domain of platelet thrombospondin- and scavenger receptor CD36...
  9. doi request reprint Iron deficiency generates secondary thrombocytosis and platelet activation in IBD: the randomized, controlled thromboVIT trial
    Stefanie Kulnigg-Dabsch
    Division of Gastroenterology and Hepatology, Department of Medicine III, Medical University of Vienna, Vienna, Austria
    Inflamm Bowel Dis 19:1609-16. 2013
    ..Here, we want to test the effect of iron replacement on platelet count and activity in IBD-associated thrombocytosis...
  10. ncbi request reprint Redox-sensitive impairment of porcine coronary artery vasodilation by hypochlorite-modified LDL
    Christian A Plass
    Institute of Physiology, Center for Physiology and Pathophysiology, Medical University of Vienna, Schwarzspanierstr 17, A 1090 Vienna, Austria
    Atherosclerosis 190:330-7. 2007
    ....
  11. doi request reprint Increased responsiveness to thrombin through protease-activated receptors (PAR)-1 and -4 in active Crohn's disease
    Werner Schmid
    Department of Anesthesiology, General Intensive Care and Pain Medicine, Division of Cardiothoracic and Vascular Anesthesia and Intensive Care, Medical University of Vienna, Vienna, Austria
    J Crohns Colitis 8:495-503. 2014
    ..Abundant thrombin generation in association with inflammation is considered a major reason for the increased risk for thromboembolic events. We therefore investigated platelet responsiveness to thrombin...
  12. ncbi request reprint CD32-mediated platelet aggregation in vitro by anti-thymocyte globulin: implication of therapy-induced in vivo thrombocytopenia
    Hendrik Jan Ankersmit
    Department of Cardiothoracic Surgery, University of Vienna, Vienna, Austria
    Am J Transplant 3:754-9. 2003
    ..Since blocking of CD32 abrogates platelet aggregation, we suggest that CD32 plays a crucial role in ATG-induced thrombocytopenia...