Research Topics
Species | Werner SchmidSummaryAffiliation: Medical University of Vienna Country: Austria Publications
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Detail Information
Publications
Hypochlorite-oxidized low density lipoproteins reduce production and bioavailability of nitric oxide in RAW 264.7 macrophages by distinct mechanismsWerner Schmid
Center for Physiology and Pathophysiology, Institute of Physiology, Medical University of Vienna, and Department of Urology, Rudolfstiftung Hospital, Vienna, Austria
Life Sci 83:50-8. 2008..By mediating these effects on production and bioavailability of NO, hyp-OxLDL might also contribute to atherogenesis by reducing the antiatherogenic effects of nitric oxide...
Estimation of platelet function under high shear conditions to assist a rapid diagnosis of Heyde SyndromeWerner Schmid
Center for Physiology and Pathophysiology, Institute of Physiology, Department of Internal Medicine III, Medical University of Vienna, Vienna 1090, Austria
Platelets 19:636-40. 2008..This test offers an easy to use diagnostic tool to evaluate platelet function in suspected Heyde Syndrome thus leading to immediate tailored patient's management...
Hypochlorite-oxidized LDL induces intraplatelet ROS formation and surface exposure of CD40L--a prominent role of CD36Alice Assinger
Institute of Physiology, Center for Physiology and Pharmacology, Medical University of Vienna, Schwarzspanierstr 17, A 1090 Vienna, Austria
Atherosclerosis 213:129-34. 2010....
Specific binding of hypochlorite-oxidized HDL to platelet CD36 triggers proinflammatory and procoagulant effectsAlice Assinger
Institute of Physiology, Center for Physiology and Pharmacology, Medical University of Vienna, Schwarzspanierstr 17, A 1090 Vienna, Austria
Atherosclerosis 212:153-60. 2010..Therefore it was the aim of this work to clarify if these platelet-activating effects result from specific binding of hypochlorite-oxidized HDL (hyp-OxHDL) to the platelet surface and to identify responsible receptors...
Platelet-stimulating effects of oxidized LDL are not attributable to toxic properties of the lipoproteinsWerner Schmid
Institute of Physiology, Center for Physiology and Pathophysiology, Medical University of Vienna, Schwarzspanierstr 17 A 1090 Vienna, Austria
Thromb Res 122:630-9. 2008..As a conclusion, platelet-activating effects of oxidatively modified LDL are not attributable to toxic properties of the lipoproteins and this finding might expand possibilities for therapeutical intervention...
Decreased VASP phosphorylation in platelets of male and female smokers of young ageAlice Assinger
Institute of Physiology, Center for Physiology and Pharmacology, Medical University of Vienna, Schwarzspanierstr 17 A 1090 Vienna, Austria
Platelets 21:596-603. 2010..Therefore, our findings add another piece of evidence to the harmful effects of smoking in both male and female smokers...
Oxidation by hypochlorite converts protective HDL into a potent platelet agonistAlice Assinger
Institute of Physiology, Center for Physiology and Pathophysiology, Medical University of Vienna, Schwarzspanierstrasse 17, Vienna, Austria
FEBS Lett 582:778-84. 2008..The observed effects are dose dependent and can be blocked by an antibody directed against the lipoprotein-binding domain of platelet thrombospondin- and scavenger receptor CD36...
Redox-sensitive impairment of porcine coronary artery vasodilation by hypochlorite-modified LDLChristian A Plass
Institute of Physiology, Center for Physiology and Pathophysiology, Medical University of Vienna, Schwarzspanierstr 17, A 1090 Vienna, Austria
Atherosclerosis 190:330-7. 2007....
CD32-mediated platelet aggregation in vitro by anti-thymocyte globulin: implication of therapy-induced in vivo thrombocytopeniaHendrik Jan Ankersmit
Department of Cardiothoracic Surgery, University of Vienna, Vienna, Austria
Am J Transplant 3:754-9. 2003..Since blocking of CD32 abrogates platelet aggregation, we suggest that CD32 plays a crucial role in ATG-induced thrombocytopenia...
