M Pircher

..Finally the benefits of the method for imaging different diseases as, e.g., age related macula degeneration (AMD) or glaucoma is demonstrated...

..We demonstrate the capability of this instrument with the measurement of the human cone spacing in perifoveal retina...

..The en-face imaging speed of the instrument is 40 fps (520 x 200 pixels). The measured precision of the method to detect small changes in optical path lengths was approximately 3 nm...

..Several volumes are stitched together to increase the total field of view. Different features of the three dimensional structure of cone photoreceptors are investigated in detail and at different eccentricities from the fovea...

..To investigate a depolarizing layer that is visible in polarization-sensitive optical coherence tomography (PS-OCT) images of the retina. To identify this layer and characterize its depolarizing effect quantitatively...

..We show that maintenance of a transverse resolution of approximately 4.4 microm can be achieved over an optical depth of 1 mm in a model eye and apply our method to imaging the human retina in vivo...

..Because of the double-beam scanning approach, our system is completely insensitive to sample motion. To demonstrate the performance of our setup, we present images of the human optic nerve head in vivo and of a human tooth...

..PS-OCT appears as a promising imaging modality for three-dimensional retinal imaging and ranging with additional contrast based on the structures' tissue-inherent polarization properties...

..To demonstrate the performance of our system we present images of the microvascular network around the fovea and around the optic nerve head of the human eye...

..We demonstrate the performance of the instrument by measuring the axial eye length of 9 patients with cataract and compare our results with those obtained using the IOL Master (Carl Zeiss Meditec Inc.)...

..Depolarization in the RPE is most pronounced close to the center of the fovea and decreases with eccentricity...

..From the retardation and thickness data, 2D birefringence maps of the RNFL are derived. Circumpapillary plots of RNFL retardation and thickness obtained by PS-SD-OCT are quantitatively compared with those obtained by SLP...

..We demonstrate that bidirectional color Doppler optical coherence tomography allows for the measurement of absolute blood flow values in vivo in human retinal vessels...

..The latter is important for improved resolution of depolarization imaging. We demonstrate our instrument for high-resolution PS-OCT imaging of the healthy human retina...

..These datasets can be interactively explored by the reader. Furthermore, we provide data of the 3D distribution of backscattered Stokes vectors to allow the reader to develop and test their own data processing algorithms...

..To compare polarization-sensitive optical coherence tomography (PS-OCT) scans to SLP images. To present a method to obtain pseudo-SLP images by PS-OCT that are free of atypical artifacts...

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..Finally we demonstrate our method by comparing images of human skin recorded in vivo with and without frequency compounding. The compounding method results in an increased contrast and improved image quality without loss of resolution...

..We implemented the method in a state of the art spectral domain PS-OCT system and demonstrate it in a test sample and human retina in vivo...

..Recognition of these disease-specific RA patterns in dry and wet forms of AMD is of particular relevance to identify the status and progression of RPE disease and may help to better estimate the functional prognosis of AMD...

..By using a state of the art spectral domain PS-OCT instrument, we demonstrate the method in healthy and diseased eyes...

..We demonstrate this method on human cornea and anterior chamber angle and present, to the best of our knowledge, the first OCT images of retardation and fast axis orientation of the anterior chamber angle region in vivo...

..To investigate and map the polarizing properties of keratoconus corneas in vitro and to compare the results with those obtained in normal corneas...

..Knowledge of the retardation and the slow axis distribution of the cornea might improve nerve fiber polarimetry for glaucoma diagnostics and could be useful for diagnosing different types of pathologies of the cornea...

..Results show errors between a few percent for high concentrations, up to 31% for low concentrations. The application of such a technique in OCT might require ultrahigh depth resolution and/or other scattered photon rejection techniques...