M Pircher

Summary

Affiliation: Medical University of Vienna
Country: Austria

Publications

  1. pmc Polarization sensitive optical coherence tomography in the human eye
    Michael Pircher
    Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, Waehringerstr 13, 1090 Vienna, Austria
    Prog Retin Eye Res 30:431-51. 2011
  2. ncbi request reprint Dynamic focus in optical coherence tomography for retinal imaging
    M Pircher
    Medical University of Vienna, Center for Biomedical Engineering and Physics, Vienna, Austria
    J Biomed Opt 11:054013. 2006
  3. ncbi request reprint Human macula investigated in vivo with polarization-sensitive optical coherence tomography
    Michael Pircher
    Center for Biomedical Engineering and Physics, Medical University of Vienna, Austria
    Invest Ophthalmol Vis Sci 47:5487-94. 2006
  4. pmc Simultaneous imaging of human cone mosaic with adaptive optics enhanced scanning laser ophthalmoscopy and high-speed transversal scanning optical coherence tomography
    M Pircher
    Center for Biomedical Engineering and Physics, Medical University of Vienna, Vienna, Austria
    Opt Lett 33:22-4. 2008
  5. pmc In vivo investigation of human cone photoreceptors with SLO/OCT in combination with 3D motion correction on a cellular level
    Michael Pircher
    Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, Waehringerstr 13, Vienna, Austria
    Opt Express 18:13935-44. 2010
  6. pmc Phase contrast coherence microscopy based on transverse scanning
    Michael Pircher
    Center for Biomedical Engineering and Physics, Medical University of Vienna, Waehringerstrasse 13, 1090 Vienna, Austria
    Opt Lett 34:1750-2. 2009
  7. doi request reprint Measurements of depolarization distribution in the healthy human macula by polarization sensitive OCT
    Bernhard Baumann
    Center for Biomedical Engineering and Physics, Medical University of Vienna, Waehringer Strasse 13, 1090 Vienna, Austria
    J Biophotonics 2:426-34. 2009
  8. ncbi request reprint High sensitive measurement of the human axial eye length in vivo with Fourier domain low coherence interferometry
    Branislav Grajciar
    Center for Biomedical Engineering and Physics, Medical University of Vienna, Waehringerstrasse 13, A 1090 Vienna, Austria
    Opt Express 16:2405-14. 2008
  9. pmc Sample motion-insensitive, full-range, complex, spectral-domain optical-coherence tomography
    Stefan Zotter
    Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, Wahringerstrasse 13, A 1090 Vienna, Austria
    Opt Lett 35:3913-5. 2010
  10. pmc Segmentation and quantification of retinal lesions in age-related macular degeneration using polarization-sensitive optical coherence tomography
    Bernhard Baumann
    Medical University of Vienna, Center for Medical Physics and Biomedical Engineering, Währinger Straße 13, Vienna, Austria
    J Biomed Opt 15:061704. 2010

Collaborators

Detail Information

Publications26

  1. pmc Polarization sensitive optical coherence tomography in the human eye
    Michael Pircher
    Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, Waehringerstr 13, 1090 Vienna, Austria
    Prog Retin Eye Res 30:431-51. 2011
    ..Finally the benefits of the method for imaging different diseases as, e.g., age related macula degeneration (AMD) or glaucoma is demonstrated...
  2. ncbi request reprint Dynamic focus in optical coherence tomography for retinal imaging
    M Pircher
    Medical University of Vienna, Center for Biomedical Engineering and Physics, Vienna, Austria
    J Biomed Opt 11:054013. 2006
    ..We show that maintenance of a transverse resolution of approximately 4.4 microm can be achieved over an optical depth of 1 mm in a model eye and apply our method to imaging the human retina in vivo...
  3. ncbi request reprint Human macula investigated in vivo with polarization-sensitive optical coherence tomography
    Michael Pircher
    Center for Biomedical Engineering and Physics, Medical University of Vienna, Austria
    Invest Ophthalmol Vis Sci 47:5487-94. 2006
    ..To investigate a depolarizing layer that is visible in polarization-sensitive optical coherence tomography (PS-OCT) images of the retina. To identify this layer and characterize its depolarizing effect quantitatively...
  4. pmc Simultaneous imaging of human cone mosaic with adaptive optics enhanced scanning laser ophthalmoscopy and high-speed transversal scanning optical coherence tomography
    M Pircher
    Center for Biomedical Engineering and Physics, Medical University of Vienna, Vienna, Austria
    Opt Lett 33:22-4. 2008
    ..We demonstrate the capability of this instrument with the measurement of the human cone spacing in perifoveal retina...
  5. pmc In vivo investigation of human cone photoreceptors with SLO/OCT in combination with 3D motion correction on a cellular level
    Michael Pircher
    Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, Waehringerstr 13, Vienna, Austria
    Opt Express 18:13935-44. 2010
    ..Several volumes are stitched together to increase the total field of view. Different features of the three dimensional structure of cone photoreceptors are investigated in detail and at different eccentricities from the fovea...
  6. pmc Phase contrast coherence microscopy based on transverse scanning
    Michael Pircher
    Center for Biomedical Engineering and Physics, Medical University of Vienna, Waehringerstrasse 13, 1090 Vienna, Austria
    Opt Lett 34:1750-2. 2009
    ..The en-face imaging speed of the instrument is 40 fps (520 x 200 pixels). The measured precision of the method to detect small changes in optical path lengths was approximately 3 nm...
  7. doi request reprint Measurements of depolarization distribution in the healthy human macula by polarization sensitive OCT
    Bernhard Baumann
    Center for Biomedical Engineering and Physics, Medical University of Vienna, Waehringer Strasse 13, 1090 Vienna, Austria
    J Biophotonics 2:426-34. 2009
    ..Depolarization in the RPE is most pronounced close to the center of the fovea and decreases with eccentricity...
  8. ncbi request reprint High sensitive measurement of the human axial eye length in vivo with Fourier domain low coherence interferometry
    Branislav Grajciar
    Center for Biomedical Engineering and Physics, Medical University of Vienna, Waehringerstrasse 13, A 1090 Vienna, Austria
    Opt Express 16:2405-14. 2008
    ..We demonstrate the performance of the instrument by measuring the axial eye length of 9 patients with cataract and compare our results with those obtained using the IOL Master (Carl Zeiss Meditec Inc.)...
  9. pmc Sample motion-insensitive, full-range, complex, spectral-domain optical-coherence tomography
    Stefan Zotter
    Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, Wahringerstrasse 13, A 1090 Vienna, Austria
    Opt Lett 35:3913-5. 2010
    ..Because of the double-beam scanning approach, our system is completely insensitive to sample motion. To demonstrate the performance of our setup, we present images of the human optic nerve head in vivo and of a human tooth...
  10. pmc Segmentation and quantification of retinal lesions in age-related macular degeneration using polarization-sensitive optical coherence tomography
    Bernhard Baumann
    Medical University of Vienna, Center for Medical Physics and Biomedical Engineering, Währinger Straße 13, Vienna, Austria
    J Biomed Opt 15:061704. 2010
    ..PS-OCT appears as a promising imaging modality for three-dimensional retinal imaging and ranging with additional contrast based on the structures' tissue-inherent polarization properties...
  11. pmc Visualization of microvasculature by dual-beam phase-resolved Doppler optical coherence tomography
    Stefan Zotter
    Center for Medical Physics and Biomedical Engineering, Medical University of Vienna, Vienna, Austria
    Opt Express 19:1217-27. 2011
    ..To demonstrate the performance of our system we present images of the microvascular network around the fovea and around the optic nerve head of the human eye...
  12. doi request reprint Retinal nerve fiber layer birefringence evaluated with polarization sensitive spectral domain OCT and scanning laser polarimetry: a comparison
    E Gotzinger
    Center for Biomedical Engineering and Physics, Medical University of Vienna, Austria
    J Biophotonics 1:129-39. 2008
    ..From the retardation and thickness data, 2D birefringence maps of the RNFL are derived. Circumpapillary plots of RNFL retardation and thickness obtained by PS-SD-OCT are quantitatively compared with those obtained by SLP...
  13. ncbi request reprint Bidirectional Doppler Fourier-domain optical coherence tomography for measurement of absolute flow velocities in human retinal vessels
    René M Werkmeister
    Center for Biomedical Engineering and Physics, Medical University of Vienna, Vienna, Austria
    Opt Lett 33:2967-9. 2008
    ..We demonstrate that bidirectional color Doppler optical coherence tomography allows for the measurement of absolute blood flow values in vivo in human retinal vessels...
  14. pmc Three-dimensional polarization sensitive OCT imaging and interactive display of the human retina
    Erich Gotzinger
    Center for Biomedical Engineering and Physics, Medical University of Vienna, Austria
    Opt Express 17:4151-65. 2009
    ..These datasets can be interactively explored by the reader. Furthermore, we provide data of the 3D distribution of backscattered Stokes vectors to allow the reader to develop and test their own data processing algorithms...
  15. pmc Retinal cone mosaic imaged with transverse scanning optical coherence tomography
    Michael Pircher
    Center for Biomedical Engineering and Physics, Medical University of Vienna, Wahringer Strasse 13, A 1090 Vienna, Austria
    Opt Lett 31:1821-3. 2006
    ....
  16. ncbi request reprint Corneal birefringence compensation for polarization sensitive optical coherence tomography of the human retina
    Michael Pircher
    Medical University of Vienna, Center for Biomedical Engineering and Physics, Wahringer Strasse 13, A 1090 Vienna, Austria
    J Biomed Opt 12:041210. 2007
    ..We implemented the method in a state of the art spectral domain PS-OCT system and demonstrate it in a test sample and human retina in vivo...
  17. pmc Polarization maintaining fiber based ultra-high resolution spectral domain polarization sensitive optical coherence tomography
    Erich Gotzinger
    Center for Biomedical Engineering and Physics, Medical University of Vienna, Austria
    Opt Express 17:22704-17. 2009
    ..The latter is important for improved resolution of depolarization imaging. We demonstrate our instrument for high-resolution PS-OCT imaging of the healthy human retina...
  18. pmc Analysis of the origin of atypical scanning laser polarimetry patterns by polarization-sensitive optical coherence tomography
    Erich Gotzinger
    Center for Biomedical Engineering and Physics, General Hospital and Medical University of Vienna, Vienna, Austria
    Invest Ophthalmol Vis Sci 49:5366-72. 2008
    ..To compare polarization-sensitive optical coherence tomography (PS-OCT) scans to SLP images. To present a method to obtain pseudo-SLP images by PS-OCT that are free of atypical artifacts...
  19. ncbi request reprint Speckle reduction in optical coherence tomography by frequency compounding
    Michael Pircher
    University of Vienna, Institute of Medical Physics, Wahringerstrasse 13, A 1090, Vienna, Austria
    J Biomed Opt 8:565-9. 2003
    ..Finally we demonstrate our method by comparing images of human skin recorded in vivo with and without frequency compounding. The compounding method results in an increased contrast and improved image quality without loss of resolution...
  20. pmc Imaging of the retinal pigment epithelium in age-related macular degeneration using polarization-sensitive optical coherence tomography
    Christian Ahlers
    Department of Ophthalmology, Medical University of Vienna, Vienna, Austria
    Invest Ophthalmol Vis Sci 51:2149-57. 2010
    ..Recognition of these disease-specific RA patterns in dry and wet forms of AMD is of particular relevance to identify the status and progression of RPE disease and may help to better estimate the functional prognosis of AMD...
  21. pmc Retinal pigment epithelium segmentation by polarization sensitive optical coherence tomography
    Erich Gotzinger
    Center for Biomedical Engineering and Physics, Medical University of Vienna, Austria
    Opt Express 16:16410-22. 2008
    ..By using a state of the art spectral domain PS-OCT instrument, we demonstrate the method in healthy and diseased eyes...
  22. ncbi request reprint Imaging of birefringent properties of keratoconus corneas by polarization-sensitive optical coherence tomography
    Erich Gotzinger
    Center for Biomedical Engineering and Physics, Medical University of Vienna, Vienna, Austria
    Invest Ophthalmol Vis Sci 48:3551-8. 2007
    ..To investigate and map the polarizing properties of keratoconus corneas in vitro and to compare the results with those obtained in normal corneas...
  23. ncbi request reprint Transversal phase resolved polarization sensitive optical coherence tomography
    Michael Pircher
    Department of Medical Physics, University of Vienna, Waehringerstr 13, A 1090 Vienna, Austria
    Phys Med Biol 49:1257-63. 2004
    ..We demonstrate this method on human cornea and anterior chamber angle and present, to the best of our knowledge, the first OCT images of retardation and fast axis orientation of the anterior chamber angle region in vivo...
  24. ncbi request reprint Measurement and imaging of birefringent properties of the human cornea with phase-resolved, polarization-sensitive optical coherence tomography
    Erich Gotzinger
    Department of Medical Physics, University of Vienna, Wahringer Strasse 13, A 1090 Vienna, Austria
    J Biomed Opt 9:94-102. 2004
    ..Knowledge of the retardation and the slow axis distribution of the cornea might improve nerve fiber polarimetry for glaucoma diagnostics and could be useful for diagnosing different types of pathologies of the cornea...
  25. ncbi request reprint Dispersion-based optical coherence tomography OCT measurement of mixture concentrations
    Seyed Morteza Bagherzadeh
    Division of Medical Physics, Medical University Vienna, Waehringer Strasse 13, A 1090 Wien Austria
    Opt Lett 32:2924-6. 2007
    ..Results show errors between a few percent for high concentrations, up to 31% for low concentrations. The application of such a technique in OCT might require ultrahigh depth resolution and/or other scattered photon rejection techniques...