Farid Moinfar

Summary

Affiliation: Medical University of Graz
Country: Austria

Publications

  1. ncbi Flat ductal intraepithelial neoplasia of the breast: evolution of Azzopardi's "clinging" concept
    Farid Moinfar
    Unit of Breast and Gynecologic Pathology, Institute of Pathology, Medical University of Graz, Graz, Austria
    Semin Diagn Pathol 27:37-48. 2010
  2. ncbi Is 'basal-like' carcinoma of the breast a distinct clinicopathological entity? A critical review with cautionary notes
    Farid Moinfar
    Unit of Breast and Gynecologic Pathology, Department of Pathology, Medical University of Graz, Graz, Austria
    Pathobiology 75:119-31. 2008
  3. doi Flat ductal intraepithelial neoplasia of the breast: a review of diagnostic criteria, differential diagnoses, molecular-genetic findings, and clinical relevance--it is time to appreciate the Azzopardi concept!
    Farid Moinfar
    Unit of Breast and Gynecologic Pathology, Department of Pathology, Medical University of Graz, Graz, Austria
    Arch Pathol Lab Med 133:879-92. 2009
  4. doi Macro-environment of breast carcinoma: frequent genetic alterations in the normal appearing skins of patients with breast cancer
    Farid Moinfar
    Department of Pathology, Medical University of Graz, Graz, Austria
    Mod Pathol 21:639-46. 2008
  5. ncbi Endometrial stromal sarcomas frequently express epidermal growth factor receptor (EGFR, HER-1): potential basis for a new therapeutic approach
    Farid Moinfar
    Institute of Pathology, Medical University Graz, Graz, Austria
    Am J Surg Pathol 29:485-9. 2005
  6. pmc JAZF1/JJAZ1 gene fusion in endometrial stromal sarcomas: molecular analysis by reverse transcriptase-polymerase chain reaction optimized for paraffin-embedded tissue
    Andelko Hrzenjak
    Institute of Pathology, Medical University of Graz, Auenbruggerplatz 25, 8036 Graz, Austria
    J Mol Diagn 7:388-95. 2005
  7. ncbi Expression of androgen receptors in benign and malignant endometrial stromal neoplasms
    Farid Moinfar
    Department of Pathology, Medical University Graz, 8036, Graz, Austria
    Virchows Arch 444:410-4. 2004
  8. ncbi Allelic imbalances in endometrial stromal neoplasms: frequent genetic alterations in the nontumorous normal-appearing endometrial and myometrial tissues
    Farid Moinfar
    Institute of Pathology, Medical University of Graz, Auenbruggerplatz 25, A 8036 Graz, Austria
    Gynecol Oncol 95:662-71. 2004
  9. ncbi Chromosomal alterations in low-grade endometrial stromal sarcoma and undifferentiated endometrial sarcoma as detected by comparative genomic hybridization
    Iris Halbwedl
    Department of Pathology, Medical University of Graz, Auenbruggerplatz 25, A 8036 Graz, Austria
    Gynecol Oncol 97:582-7. 2005
  10. doi Chromosomal aberrations as detected by array comparative genomic hybridization in early low-grade intraepithelial neoplasias of the breast
    Elvira Stacher
    Institute of Pathology, Medical University of Graz, Graz, Austria
    Histopathology 59:549-55. 2011

Detail Information

Publications33

  1. ncbi Flat ductal intraepithelial neoplasia of the breast: evolution of Azzopardi's "clinging" concept
    Farid Moinfar
    Unit of Breast and Gynecologic Pathology, Institute of Pathology, Medical University of Graz, Graz, Austria
    Semin Diagn Pathol 27:37-48. 2010
    ..This type of breast lesion is an indicator for coexisting neoplastic lesions, such as low-grade ductal intraepithelial neoplasia (atypical ductal hyperplasia/low-grade ductal carcinoma in situ) and lobular intraepithelial neoplasia...
  2. ncbi Is 'basal-like' carcinoma of the breast a distinct clinicopathological entity? A critical review with cautionary notes
    Farid Moinfar
    Unit of Breast and Gynecologic Pathology, Department of Pathology, Medical University of Graz, Graz, Austria
    Pathobiology 75:119-31. 2008
    ....
  3. doi Flat ductal intraepithelial neoplasia of the breast: a review of diagnostic criteria, differential diagnoses, molecular-genetic findings, and clinical relevance--it is time to appreciate the Azzopardi concept!
    Farid Moinfar
    Unit of Breast and Gynecologic Pathology, Department of Pathology, Medical University of Graz, Graz, Austria
    Arch Pathol Lab Med 133:879-92. 2009
    ..The lesion remained widely unrecognized and/or ignored until recent years when its neoplastic nature was confirmed at the molecular-genetic level...
  4. doi Macro-environment of breast carcinoma: frequent genetic alterations in the normal appearing skins of patients with breast cancer
    Farid Moinfar
    Department of Pathology, Medical University of Graz, Graz, Austria
    Mod Pathol 21:639-46. 2008
    ..These data indicate that more global assessment of tumor micro- and macro-environment is crucial for our understanding of breast carcinogenesis...
  5. ncbi Endometrial stromal sarcomas frequently express epidermal growth factor receptor (EGFR, HER-1): potential basis for a new therapeutic approach
    Farid Moinfar
    Institute of Pathology, Medical University Graz, Graz, Austria
    Am J Surg Pathol 29:485-9. 2005
    ..This finding may provide the basis for a new therapeutic strategy using monoclonal antibodies against EGFR (such as cetuximab) or small molecule inhibitors of EGFR (such as gefitinib) in patients with endometrial sarcomas...
  6. pmc JAZF1/JJAZ1 gene fusion in endometrial stromal sarcomas: molecular analysis by reverse transcriptase-polymerase chain reaction optimized for paraffin-embedded tissue
    Andelko Hrzenjak
    Institute of Pathology, Medical University of Graz, Auenbruggerplatz 25, 8036 Graz, Austria
    J Mol Diagn 7:388-95. 2005
    ..In combination with other established methods, accurate reverse transcriptase-polymerase chain reaction analysis of JAZF1/JJAZ1 gene fusion may be useful in diagnosing difficult or unusual ESS/UES cases...
  7. ncbi Expression of androgen receptors in benign and malignant endometrial stromal neoplasms
    Farid Moinfar
    Department of Pathology, Medical University Graz, 8036, Graz, Austria
    Virchows Arch 444:410-4. 2004
    ..In addition to determination of ER and PR, the results of immunohistochemical examination of AR in these rare uterine tumors may have some impact on the postoperative management of the patients...
  8. ncbi Allelic imbalances in endometrial stromal neoplasms: frequent genetic alterations in the nontumorous normal-appearing endometrial and myometrial tissues
    Farid Moinfar
    Institute of Pathology, Medical University of Graz, Auenbruggerplatz 25, A 8036 Graz, Austria
    Gynecol Oncol 95:662-71. 2004
    ..The aim of this study was to examine the possibility of loss of heterozygosity (LOH) and microsatellite instability (MIS) in different tissue components of ESS...
  9. ncbi Chromosomal alterations in low-grade endometrial stromal sarcoma and undifferentiated endometrial sarcoma as detected by comparative genomic hybridization
    Iris Halbwedl
    Department of Pathology, Medical University of Graz, Auenbruggerplatz 25, A 8036 Graz, Austria
    Gynecol Oncol 97:582-7. 2005
    ..The aim of the present study was to characterize the karyotypic abnormalities in these malignant mesenchymal tumors and to find specific chromosomal aberrations with eventual correlation with histologic grades...
  10. doi Chromosomal aberrations as detected by array comparative genomic hybridization in early low-grade intraepithelial neoplasias of the breast
    Elvira Stacher
    Institute of Pathology, Medical University of Graz, Graz, Austria
    Histopathology 59:549-55. 2011
    ..Frequently, it occurs concomitantly with lobular intraepithelial neoplasia (LIN). We aimed to elucidate chromosomal aberrations in these early neoplastic breast lesions with the use of array comparative genomic hybridization analysis...
  11. pmc Histone deacetylase inhibitor vorinostat suppresses the growth of uterine sarcomas in vitro and in vivo
    Andelko Hrzenjak
    Lore Saldow Research Unit for Molecular Pathology of Gynecologic Tumors, Department of Pathology, Medical University of Graz, Auenbruggerplatz 25, 8036 Graz, Austria
    Mol Cancer 9:49. 2010
    ..We analyzed the influence of vorinostat on expression of different HDACs, p21(WAF1) and activation of apoptosis. Finally, we examined the antitumor effects of vorinostat on uterine sarcoma in vivo...
  12. ncbi Mammary NOS-type sarcoma with CD10 expression: a rare entity with features of myoepithelial differentiation
    Sebastian Leibl
    Institute of Pathology, Medical University of Graz, Graz, Austria
    Am J Surg Pathol 30:450-6. 2006
    ..The immunophenotype of NOS-type sarcomas with CD10 expression suggests that these neoplasms represent a mammary sarcoma variant with myoepithelial features...
  13. ncbi Valproate inhibition of histone deacetylase 2 affects differentiation and decreases proliferation of endometrial stromal sarcoma cells
    Andelko Hrzenjak
    Department of Pathology, Medical University of Graz, Auenbruggerplatz 25, 8036 Graz, Austria
    Mol Cancer Ther 5:2203-10. 2006
    ..Our results suggest that HDAC2 might be considered as potential drug target in the therapy of ESS and that HDAC inhibitors should be further evaluated in clinical trials in ESS...
  14. ncbi Inverse correlation of secreted frizzled-related protein 4 and beta-catenin expression in endometrial stromal sarcomas
    Andelko Hrzenjak
    Department of Pathology, Medical University, Graz, Austria
    J Pathol 204:19-27. 2004
    ..SFRP4 may therefore be a putative tumour suppressor involved in deregulation of the Wnt pathway and in the pathogenesis of ESS and UES...
  15. ncbi Metaplastic breast carcinomas: are they of myoepithelial differentiation?: immunohistochemical profile of the sarcomatoid subtype using novel myoepithelial markers
    Sebastian Leibl
    Department of Pathology, Medical University of Graz, Graz, Austria
    Am J Surg Pathol 29:347-53. 2005
    ..CD29 and 14-3-3sigma represent valuable novel myoepithelial markers in these diagnostically difficult cases...
  16. doi Androgen receptor expression in breast cancer patients tested for BRCA1 and BRCA2 mutations
    Gunda Pristauz
    Department of Obstetrics and Gynecology, Medical University of Graz, Graz, Austria
    Histopathology 57:877-84. 2010
    ....
  17. doi Bilateral ovarian well-differentiated Sertoli-Leydig cell tumors with heterologous elements associated with unilateral serous cystadenoma--a case report
    Elvira Stacher
    Institute of Pathology, Department of Gynecology and Obstetrics, Medical University of Graz, Auenbruggerplatz 25, Graz, Austria
    Int J Gynecol Pathol 29:419-22. 2010
    ..Furthermore, on the left side it also was associated with a serous cystadenoma...
  18. ncbi Ovarian granulosa cell tumors frequently express EGFR (Her-1), Her-3, and Her-4: An immunohistochemical study
    Sebastian Leibl
    Department of Pathology, Medical University of Graz, Auenbruggerplatz 25, A 8036 Graz, Austria
    Gynecol Oncol 101:18-23. 2006
    ..Combined chemotherapy and radiotherapy are currently used for patients with advanced or recurrent disease. The aim of this study was to investigate the possible eligibility of patients with GCTs for anti-Her therapy...
  19. ncbi Evaluation of the prognostic significance of androgen receptor expression in metastatic breast cancer
    Walter Schippinger
    Division of Oncology, Department of Internal Medicine, Medical University of Graz, Auenbruggerplatz 15, 8036 Graz, Austria
    Virchows Arch 449:24-30. 2006
    ..In conclusion, SAR is significantly longer in patients with AR-expressing breast carcinoma. However, AR expression is not an independent prognostic factor for SAR in metastatic breast cancer...
  20. ncbi Androgen receptors are frequently expressed in mammary and extramammary Paget's disease
    Bernadette Liegl
    Department of Pathology, Medical University of Graz, Graz, Austria
    Mod Pathol 18:1283-8. 2005
    ..The knowledge about frequent expression of AR in Paget's disease could lead to the development of a new adjuvant therapy, particularly in patients with recurrent disease...
  21. ncbi Isolated recurrence at the residual uterine cervix after abdominal radical trachelectomy for early cervical cancer
    Arnim A Bader
    Department of Obstetrics and Gynecology, Medical University of Graz, Auenbruggerplatz 14, A 8036 Graz, Austria
    Gynecol Oncol 99:785-7. 2005
    ..We report an isolated recurrence at the residual cervix shortly after abdominal radical trachelectomy for cervical cancer...
  22. ncbi Effects of Targeting Endometrial Stromal Sarcoma Cells via Histone Deacetylase and PI3K/AKT/mTOR Signaling
    Ping Quan
    Institute of Pathology, Medical University of Graz, Graz, Austria
    Anticancer Res 34:2883-97. 2014
    ..Conclusion: SAHA combined with inhibition of PI3K and mTOR could represent an efficient therapy option for patients with ESS. ..
  23. ncbi Androgen receptors frequently are expressed in breast carcinomas: potential relevance to new therapeutic strategies
    Farid Moinfar
    Department of Pathology, School of Medicine, Karl Franzens University Graz, Graz, Austria
    Cancer 98:703-11. 2003
    ..The aim of the current study was to examine the presence of androgen receptors (AR) in breast carcinomas...
  24. ncbi Regulation of the E2F family: a further step in understanding ovarian cancer biology
    Edgar Petru
    Department of Obstetrics and Gynecology, Medical University of Graz, Graz, Austria
    Cancer Biol Ther 5:777-8. 2006
  25. doi Molecular classification of breast carcinomas with particular emphasis on "basal-like" carcinoma: a critical review
    Mohammad Ali Lavasani
    Unit of Breast and Gynecologic Pathology, Department of Pathology, Medical University of Graz, Graz, Austria
    J Biophotonics 5:345-66. 2012
    ....
  26. doi Diagnostic yield of touch imprint cytology of prostate core needle biopsies
    Sebastian Mannweiler
    Institute of Pathology, Medical University of Graz, Auenbruggerplatz 25, A 8036, Graz, Austria
    Pathol Oncol Res 15:97-101. 2009
    ..We conclude, that in problematic cases the additional use of touch imprint cytology and serial sectioning of prostate core needle biopsies significantly improve the diagnostic accuracy...
  27. ncbi Is intraoperative frozen section analysis of pelvic lymph nodes accurate after neoadjuvant chemotherapy in patients with cervical cancer?
    Arnim A Bader
    Department of Obstetrics and Gynecology, Medical University of Graz, Auenbruggerplatz 14, A 8036 Graz, Austria
    Gynecol Oncol 103:106-12. 2006
    ..We analyzed the accuracy of frozen section examination of pelvic lymph nodes in patients after NACT for cervical cancer...
  28. ncbi Uterine sarcomas
    Farid Moinfar
    Department of Pathology, Graz University School of Medicine, Austria
    Pathology 39:55-71. 2007
    ..Clinical information necessary for accurate diagnosis of these lesions is emphasised. A multidisciplinary approach to management of patients with uterine sarcomas is essential for optimal management...
  29. ncbi A case report of an ependymoblastoma in the rectovaginal space and a review of the literature
    Elisabeth Smolle
    Institute of Pathology, Medical University of Graz, Auenbruggerplatz 25, A 8036 Graz, Austria
    Anticancer Res 34:819-27. 2014
    ..They are most frequently located intraventricularly, but they may also occur in the spinal cord or, very seldom, at extraneural sites. Here we report a case of an ectopic ependymoma, arising in the pelvic cavity...
  30. pmc Molecular evidence for the bi-clonal origin of neuroendocrine tumor derived metastases
    Beate Rinner
    Center for Medical Research, Medical University of Graz, Stiftingtalstra├če 24, Graz, 8010, Austria
    BMC Genomics 13:594. 2012
    ....
  31. ncbi Metaplastic sarcomatoid carcinoma of the breast: not a misnomer
    Sebastian Leibl
    Am J Surg Pathol 30:1052-3; author reply 1053-5. 2006
  32. ncbi Accurate size measurement in infiltrating lobular carcinoma of the breast--gross versus microscopic evaluation
    Farid Moinfar
    Breast J 12:509-10. 2006
  33. ncbi Combined E-cadherin and high molecular weight cytokeratin immunoprofile differentiates lobular, ductal, and hybrid mammary intraepithelial neoplasias
    Gary L Bratthauer
    Department of Gynecologic and Breast Pathology, Armed Forces Institute of Pathology, Washington, DC 20306 6000, USA
    Hum Pathol 33:620-7. 2002
    ..This group needs further evaluation for better understanding of its significance, pattern of progression, and behavior...