Affiliation: Medical University of Vienna
- Indirect CB2 receptor and mediator-dependent stimulation of human whole-blood neutrophils by exogenous and endogenous cannabinoidsBirgit Kraft
Department of Anesthesiology and Intensive Care Medicine B, Medical University of Vienna, Austria
J Pharmacol Exp Ther 315:641-7. 2005..Results of our further experiments suggest that products of the arachidonic acid metabolism are mediators of the cannabinoid-induced enhancement of the respiratory burst reaction of whole-blood PMNs...
- Lack of analgesia by oral standardized cannabis extract on acute inflammatory pain and hyperalgesia in volunteersBirgit Kraft
Department of Anesthesiology and Intensive Care Medicine A, Medical University of Vienna, Vienna, Austria
Anesthesiology 109:101-10. 2008..Therefore, the aim of this study was to investigate the effects of oral cannabis extract in two different human models of acute inflammatory pain and hyperalgesia...
- Cannabinoid receptor-independent suppression of the superoxide generation of human neutrophils (PMN) by CP55 940, but not by anandamideBirgit Kraft
Department of Anesthesiology, Medical University of Vienna, Waehringer Guertel 18 20, A 1090 Vienna, Austria
Life Sci 75:969-77. 2004..This inhibitory effect of CP55 940 was not CB-receptor-mediated. In contrast, anandamide and methanandamide did not alter the oxidative microbicidal PMN function...
- The procoagulatory effects of delta-9-tetrahydrocannabinol in human plateletsEngelbert Deusch
Department of General Anesthesiology and Intensive Care B, Vienna Medical University, General Hospital Vienna, Waehringer Guertel 18 20, A 1090 Vienna, Austria
Anesth Analg 99:1127-30, table of contents. 2004..However, further in vivo studies are warranted to evaluate the role of cannabinoid receptors in mediating the demonstrated procoagulatory effect of THC...
- No carnitine palmitoyltransferase deficiency in skeletal muscle in 18 malignant hyperthermia susceptible individualsThomas Wieser
Department of Anaesthesia and Pain Management, Medical University of Vienna, Allgemeines Krankenhaus, Wahringer Gurtel 18 20, 1090 Vienna, Austria
Neuromuscul Disord 18:471-4. 2008..Thus our data do not support the hypothesis that susceptibility to malignant hyperthermia has an effect on the carnitine palmitoyltransferase enzyme system...
- Opioid medication and driving abilityHans G Kress
Department of Anaesthesiology and Intensive Care Medicine, Medical University of Vienna, Waehringer Guertel 18 20, A 1090 Vienna, Austria
Eur J Pain 9:141-4. 2005..Based on these data, the prerequisites and restrictions for driving under chronic opioid medication are outlined and practical guidelines are proposed...
- Novel ryanodine receptor mutation that may cause malignant hyperthermiaAlexius Kaufmann
Department of Special Anesthesia and Pain Management, Medical University of Vienna, Wahringer Gurtel 18 20, Vienna A 1090, Austria
Anesthesiology 109:457-64. 2008..The aim of this study was to provide functional data that establish a potential link between this new variant and susceptibility to MH, and thus enable application in genetic tests...
- No evidence for direct modulatory effects of delta 9-tetrahydrocannabinol on human polymorphonuclear leukocytesEngelbert Deusch
University Hospital AKH, Vienna Medical University, A 1090 Vienna, Austria
J Neuroimmunol 141:99-103. 2003..Thus, circulating human PMN from healthy individuals remain unaffected by Delta(9)-THC due to the absence of functional CB(2)-receptor expression...