Research Topics
| Renate KainSummaryAffiliation: Medical University of Vienna Country: Austria Publications
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Detail Information
Publications
What is the evidence for antibodies to LAMP-2 in the pathogenesis of ANCA associated small vessel vasculitis?Renate Kain
Clinical Institute of Pathology, Medical University of Vienna, Vienna, Austria
Curr Opin Rheumatol 25:26-34. 2013..It addresses recent controversies over prevalence of anti-hLAMP-2 antibodies as well as their potential for diagnosis and monitoring disease activity...
High prevalence of autoantibodies to hLAMP-2 in anti-neutrophil cytoplasmic antibody-associated vasculitisRenate Kain
Clinical Institute of Pathology, Medical University of Vienna, Vienna, Austria
J Am Soc Nephrol 23:556-66. 2012..Large-scale prospective studies are now needed to determine whether they are pathogenic or merely an epiphenomenon...
Anti-hLAMP2-antibodies and dual positivity for anti-GBM and MPO-ANCA in a patient with relapsing pulmonary-renal syndromeChristoph Etter
Division of Nephrology, University Hospital Zurich, Zurich, Switzerland
BMC Nephrol 12:26. 2011..Whilst anti-GBM disease is considered a non-relapsing condition, the long-term course of double-positive patients is less predictable...
Molecular mimicry in pauci-immune focal necrotizing glomerulonephritisRenate Kain
Department of Pathology, Medical University of Vienna, Wahringer Gurtel 18 20, 1090 Wien, Austria
Nat Med 14:1088-96. 2008..Thus, FimH-triggered autoimmunity to LAMP-2 provides a previously undescribed clinically relevant molecular mechanism for the development of pauci-immune FNGN...
Pathogenesis of small vessel vasculitis associated with autoantibodies to neutrophil cytoplasmic antigens: new insights from animal modelsRenate Kain
Institute of Clinical Pathology, Medical University of Vienna, Wahringer Gurtel, Vienna, Austria
Curr Opin Rheumatol 22:15-20. 2010..In-vitro experiments have provided invaluable insight into the molecular mechanisms of antibody action and their subcellular effects; however, they may not reflect the in-vivo situation that can only be assessed in animal models...
Histological and clinical predictors of early and late renal outcome in ANCA-associated vasculitisIrmgard Neumann
Department of Nephrology, Wilhelminenspital, Vienna, Austria
Nephrol Dial Transplant 20:96-104. 2005..Renal involvement remains a major determinant in antineutrophil cytoplasmic autoantibody-associated small vessel vasculitis (AASV). While some patients may develop persistent renal damage, others have a favourable outcome...
Gross proteinuria and subacute renal failure after coronary angiography - a case report of cholesterol crystal embolizationPeter Biesenbach
Internal Medicine III Clinical Division of Nephrology and Dialysis, Medical University of Vienna, Vienna, Austria
Wien Klin Wochenschr 122:251-4. 2010..Identification of high-risk patients is of utmost importance as efficient therapeutic strategies do not exist...
Glomerular immune deposits are associated with increased proteinuria in patients with ANCA-associated crescentic nephritisIrmgard Neumann
Department of Nephrology, Wilhelminenspital, Vienna, Austria
Nephrol Dial Transplant 18:524-31. 2003..In some patients, however, significant amounts of immune deposits may be detected. Therefore, we evaluated the clinical significance of these immune deposits in anti-neutrophil cytoplasmic autoantibody (ANCA)-associated pauci-immune CGN...
