R M Bonelli

Summary

Affiliation: Medical University of Graz
Country: Austria

Publications

  1. ncbi request reprint Huntington's disease: present treatments and future therapeutic modalities
    Raphael M Bonelli
    University Clinic of Psychiatry, Karl Franzens University Graz, Graz University Clinic of Neurology, University of Innsbruck, Innsbruck, Austria
    Int Clin Psychopharmacol 19:51-62. 2004
  2. ncbi request reprint A review of the treatment options for Huntington's disease
    Raphael M Bonelli
    University of Clinic of Psychiatry, Karl Franzens University Graz, Graz, Austria
    Expert Opin Pharmacother 5:767-76. 2004
  3. ncbi request reprint Neuroprotection in Huntington's disease: a 2-year study on minocycline
    Raphael M Bonelli
    Department of Psychiatry, Graz Medical University, Graz, Austria
    Int Clin Psychopharmacol 19:337-42. 2004
  4. ncbi request reprint The influence of psychotropic drugs on cerebral cell death: female neurovulnerability to antipsychotics
    Raphael M Bonelli
    University Clinic of Psychiatry, Graz Medical University, Graz, Austria
    Int Clin Psychopharmacol 20:145-9. 2005
  5. ncbi request reprint Ziprasidone in Huntington's disease: the first case reports
    Raphael M Bonelli
    University Clinic of Psychiatry, Karl Franzens University Graz, Austria
    J Psychopharmacol 17:459-60. 2003
  6. ncbi request reprint Basal ganglia volumetric studies in affective disorder: what did we learn in the last 15 years?
    R M Bonelli
    University Clinic of Psychiatry, Graz Medical University, Graz, Austria
    J Neural Transm 113:255-68. 2006
  7. ncbi request reprint Pharmacological management of Huntington's disease: an evidence-based review
    Raphael M Bonelli
    University Clinic of Psychiatry, Department of Psychiatry, Graz Medical University, Auenbruggerplatz 31, A 8036 Graz, Austria
    Curr Pharm Des 12:2701-20. 2006
  8. ncbi request reprint A systematic review of the treatment studies in Huntington's disease since 1990
    Raphael M Bonelli
    University Clinic of Psychiatry, Graz Medical University, Auenbruggerplatz 31, A 8036 Graz, Austria
    Expert Opin Pharmacother 8:141-53. 2007
  9. pmc Frontal-subcortical circuitry and behavior
    Raphael M Bonelli
    Department of Psychiatry, Graz Medical University, Auenbruggerplatz 31, 8036 Graz, Austria
    Dialogues Clin Neurosci 9:141-51. 2007
  10. ncbi request reprint Apraxia of eyelid closure in Huntington's disease
    R M Bonelli
    Department of Neurology and Psychiatry, Hospital BHB Eggenberg, Graz, Austria
    J Neural Transm 109:197-201. 2002

Collaborators

Detail Information

Publications35

  1. ncbi request reprint Huntington's disease: present treatments and future therapeutic modalities
    Raphael M Bonelli
    University Clinic of Psychiatry, Karl Franzens University Graz, Graz University Clinic of Neurology, University of Innsbruck, Innsbruck, Austria
    Int Clin Psychopharmacol 19:51-62. 2004
    ..Finally, some cellular mechanisms are discussed in this paper because they are essential for future neuroprotective modalities, such as minocycline, unsaturated fatty acids or riluzole...
  2. ncbi request reprint A review of the treatment options for Huntington's disease
    Raphael M Bonelli
    University of Clinic of Psychiatry, Karl Franzens University Graz, Graz, Austria
    Expert Opin Pharmacother 5:767-76. 2004
    ..Psychiatric symptoms, on the other hand, are often amenable to treatment and relief of these symptoms may provide significant improvement in quality of life...
  3. ncbi request reprint Neuroprotection in Huntington's disease: a 2-year study on minocycline
    Raphael M Bonelli
    Department of Psychiatry, Graz Medical University, Graz, Austria
    Int Clin Psychopharmacol 19:337-42. 2004
    ..A long-term, double-blind, placebo-controlled trial appears highly warranted for definitively establishing the value of minocycline in HD...
  4. ncbi request reprint The influence of psychotropic drugs on cerebral cell death: female neurovulnerability to antipsychotics
    Raphael M Bonelli
    University Clinic of Psychiatry, Graz Medical University, Graz, Austria
    Int Clin Psychopharmacol 20:145-9. 2005
    ..Finally, the possible connection between the observed increased cerebral cell death and tardive dyskinesia, the most threatening side-effect in antipsychotic therapy, is discussed...
  5. ncbi request reprint Ziprasidone in Huntington's disease: the first case reports
    Raphael M Bonelli
    University Clinic of Psychiatry, Karl Franzens University Graz, Austria
    J Psychopharmacol 17:459-60. 2003
    ..We report three genetically confirmed HD patients who improved significantly in several categories of the motor scale of the Unified HD Rating Scale...
  6. ncbi request reprint Basal ganglia volumetric studies in affective disorder: what did we learn in the last 15 years?
    R M Bonelli
    University Clinic of Psychiatry, Graz Medical University, Graz, Austria
    J Neural Transm 113:255-68. 2006
    ....
  7. ncbi request reprint Pharmacological management of Huntington's disease: an evidence-based review
    Raphael M Bonelli
    University Clinic of Psychiatry, Department of Psychiatry, Graz Medical University, Auenbruggerplatz 31, A 8036 Graz, Austria
    Curr Pharm Des 12:2701-20. 2006
    ..Despite the increasing body of published reports on pharmacological interventions in Huntington's disease (HD), an evidence based review (EBR) of treatment studies has not yet been published...
  8. ncbi request reprint A systematic review of the treatment studies in Huntington's disease since 1990
    Raphael M Bonelli
    University Clinic of Psychiatry, Graz Medical University, Auenbruggerplatz 31, A 8036 Graz, Austria
    Expert Opin Pharmacother 8:141-53. 2007
    ..The authors conducted a systematic review of pharmacological therapy in HD using the available papers that were published between 1990 and 2006...
  9. pmc Frontal-subcortical circuitry and behavior
    Raphael M Bonelli
    Department of Psychiatry, Graz Medical University, Auenbruggerplatz 31, 8036 Graz, Austria
    Dialogues Clin Neurosci 9:141-51. 2007
    ....
  10. ncbi request reprint Apraxia of eyelid closure in Huntington's disease
    R M Bonelli
    Department of Neurology and Psychiatry, Hospital BHB Eggenberg, Graz, Austria
    J Neural Transm 109:197-201. 2002
    ..No report on HD is available so far, although oculomotor disturbances are quite common in this disease...
  11. doi request reprint Combating depression in Huntington's disease: effective antidepressive treatment with venlafaxine XR
    Anna K Holl
    University Clinic of Psychiatry bUniversity Clinic of Neurosurgery, Graz Medical University, Auenbruggerplatz 31, Graz, Austria
    Int Clin Psychopharmacol 25:46-50. 2010
    ..Venlafaxine XR is highly effective in the treatment of depression in HD, although it may produce unpleasant side effects. Further studies are required to establish the most suitable treatment for depression in HD...
  12. ncbi request reprint Pramipexole ameliorates neurologic and psychiatric symptoms in a Westphal variant of Huntington's disease
    Raphael M Bonelli
    Department of Neurology and Psychiatry, Hospital BHB Eggenberg, Graz, Austria
    Clin Neuropharmacol 25:58-60. 2002
    ..In this study, however, we report a 34-year-old woman with this rare variant who showed a clear-cut improvement in motor function and depressive symptoms after treatment with pramipexole, a new dopamine agonist...
  13. ncbi request reprint Compactotomy in Huntington's chorea
    R M Bonelli
    Department of Neurology and Psychiatry, Hospital BHB Eggenberg, Graz, Austria
    Med Hypotheses 57:491-6. 2001
    ..Several lines of evidence in recent neurophysiological research support our hypothesis and are discussed below...
  14. ncbi request reprint High-dose olanzapine in Huntington's disease
    R M Bonelli
    Department of Neurology and Psychiatry, Hospital BHB Eggenberg, Graz, Austria
    Int Clin Psychopharmacol 17:91-3. 2002
    ..This effect lasted for 5 months. We conclude that high-dose olanzapine appears to be useful in grave choreatic attacks...
  15. ncbi request reprint Sexuality in multiple sclerosis
    E Z Schmidt
    University Clinic of Psychiatry, Medical University of Graz, Graz, Austria
    J Neural Transm 112:1201-11. 2005
    ..Positive familial support can often help the patient in coping with the illness, nonetheless problems with changing roles and multiple-sclerosis-minimizing can improve the need of contacts to outstanding persons...
  16. doi request reprint Ideomotor limb apraxia in Huntington's disease: a case-control study
    Anna K Hödl
    University Clinic of Psychiatry, Graz Medical University, Auenbruggerplatz 31, 8036, Graz, Austria
    J Neurol 255:331-9. 2008
    ..The aim of our study is to determine the correlation between the occurrence of ideomotor limb apraxia and neuropsychological deficits in HD...
  17. doi request reprint Structural neuroimaging of the basal ganglia in schizophrenic patients: a review
    Gerrit N Brandt
    Department of Psychiatry, Medical University of Graz, Graz, Austria
    Wien Med Wochenschr 158:84-90. 2008
    ..Further studies are warranted for a better understanding of the mechanisms, which may lead to structural basal ganglia abnormalities, with medication effects demanding particular attention...
  18. doi request reprint Sexuality in Huntington's disease
    Eva Z Schmidt
    Department of Psychiatry, Medical University of Graz, Graz, Austria
    Wien Med Wochenschr 158:78-83. 2008
    ..Treatment options for HD patients with sexual disorder are only reported sporadically, guidelines can only be obtained from non-HD patients and further research is needed...
  19. ncbi request reprint Olanzapine for Huntington's disease: an open label study
    Raphael M Bonelli
    Department of Neurology and Psychiatry, Hospital BHB Eggenberg, Graz, Austria
    Clin Neuropharmacol 25:263-5. 2002
    ..High-dose olanzapine seems to be useful in choreatic HD patients. A double blind, placebo-controlled trial appears warranted to definitively establish the symptomatic value of olanzapine in HD...
  20. ncbi request reprint Minocycline for Huntington's disease: an open label study
    Raphael M Bonelli
    Department of Neurology and Psychiatry, Hospital BHB Eggenberg, Graz, Austria
    Neurology 60:883-4. 2003
  21. ncbi request reprint Amantadine in the akinetic-rigid variant of Huntington's disease
    Markus K Magnet
    Karl Franzens University Graz, Graz, Austria
    Ann Pharmacother 38:1194-6. 2004
    ..To report the effects of amantadine on an akinetic-rigid variant of Huntington's disease (HD)...
  22. ncbi request reprint Cerebrospinal fluid tissue transglutaminase in vascular dementia
    Raphael M Bonelli
    Department of Neurology and Psychiatry, Hospital BHB Eggenberg, Bergstrasse 27, A 8021 Graz, Austria
    J Neurol Sci 203:207-9. 2002
    ..It may serve as completion of CSF analysis in diagnosis of dementing disorders and be a simple way of assessing the efficacy of possible new anti-apoptotic drugs...
  23. ncbi request reprint Zotepine in Huntington's disease
    Raphael M Bonelli
    Department of Neurology and Psychiatry, Hospital BHB Eggenberg, Bergstrasse 27, A 8021 Graz, Austria
    Hum Psychopharmacol 18:227-9. 2003
    ..This is the first description of zotepine in HD. Our findings suggest that zotepine is useful in the treatment of HD chorea. Controlled trials of its use in HD would be welcome...
  24. ncbi request reprint Riluzole and olanzapine in Huntington's disease
    Raphael M Bonelli
    Eur J Neurol 9:183-4. 2002
  25. ncbi request reprint Huntington's disease and minocycline
    Anna K Hödl
    Mov Disord 20:510-1; author reply 511. 2005
  26. ncbi request reprint Cerebrospinal fluid tissue transglutaminase as a biochemical marker for Alzheimer's disease
    Raphael M Bonelli
    Department of Neurology and Psychiatry, Hospital BHB Eggenberg, Bergstrasse 27, A 8021 Graz, Austria
    Neurobiol Dis 11:106-10. 2002
    ..It may serve as completion of CSF analysis in the diagnosis of dementing disorders and may be a simple way of assessing the efficacy of possible new antiapoptotic drugs...
  27. ncbi request reprint Deep brain stimulation in Huntington's disease
    Raphael M Bonelli
    Mov Disord 17:429-30; author reply 431-2. 2002
  28. ncbi request reprint Mirtazapine in suicidal Huntington's disease
    Raphael M Bonelli
    Ann Pharmacother 37:452. 2003
  29. ncbi request reprint Drug holiday in Huntington's disease
    Eva Z Schmidt
    Ann Pharmacother 39:773. 2005
  30. ncbi request reprint Prevalence of autoimmune thyroiditis and non-immune thyroid disease in multiple sclerosis
    Gerald Niederwieser
    Department of Neurology, Barmherzige Brüder Hospital, Bergstrasse 27, 8021 Graz, Austria
    J Neurol 250:672-5. 2003
    ..Longitudinal studies comparing MS patients with or without AIT could show whether there is an influence of AIT on the disease course or progression...
  31. ncbi request reprint Olanzapine-associated seizure
    Raphael M Bonelli
    Ann Pharmacother 37:149-50. 2003
  32. ncbi request reprint Quetiapine in Huntington's disease: a first case report
    Raphael M Bonelli
    J Neurol 249:1114-5. 2002
  33. ncbi request reprint Apoptotic cascades as possible targets for inhibiting cell death in Huntington's disease
    Lindsay R Pattison
    Department of Biochemistry and Molecular Biology, The College of Wooster, 1189 Beall Avenue, Wooster, OH 44691, USA
    J Neurol 253:1137-42. 2006
    ....
  34. ncbi request reprint Cortical blood flow during rest and Wisconsin Card Sorting Test performance in schizophrenia
    Felipe Ortuno
    University Clinic of Psychiatry, University of Navarra College of Medicine, Pamplona, Spain
    Wien Med Wochenschr 156:179-84. 2006
    ..The aim of this study is to examine if patients with schizophrenia differ in prefrontal, orbitofrontal, temporal, parietal and occipital blood flow from healthy controls during performance of the Wisconsin Card Sorting Test (WCST)...
  35. ncbi request reprint Why minocycline is helpful in Huntington's disease
    Raphael M Bonelli
    J Psychopharmacol 17:461. 2003