S Aharinejad

Summary

Affiliation: Medical University of Vienna
Country: Austria

Publications

  1. ncbi request reprint Selective upregulation of vascular endothelial growth factor receptors neuropilin-1 and -2 in human neuroblastoma
    Mitra Fakhari
    Department of Pediatric Surgery, University of Vienna, Vienna, Austria
    Cancer 94:258-63. 2002
  2. doi request reprint First hand accounts of events in the laboratory of Prof. Eduard Pernkopf. Interviews by Seyed Hossein Aharinejad and Stephen W Carmichael
    Walter Kraus
    Center for Anatomy and Cell Biology, Medical University of Vienna, A 1090 Vienna, Austria
    Clin Anat 26:297-303. 2013
  3. pmc Serum glutathione S-transferase P1 1 in prediction of cardiac function
    Olena Andrukhova
    Center for Anatomy and Cell Biology, Department of Cardiovascular Research, Vienna, Austria
    J Card Fail 18:253-61. 2012
  4. doi request reprint Low serum IGF-1 is a risk factor for cardiac allograft vasculopathy in cardiac transplant recipients
    Seyedhossein Aharinejad
    Department of Cardiac Surgery, Medical University of Vienna, Vienna, Austria
    Transplantation 93:309-13. 2012
  5. pmc Association of CD14+ monocyte-derived progenitor cells with cardiac allograft vasculopathy
    Mohamed Salama
    Department of Cardiothoracic Surgery, Center for Anatomy and Cell Biology, Medical University of Vienna, Vienna, Austria
    J Thorac Cardiovasc Surg 142:1246-53. 2011
  6. pmc Colony-stimulating factor-1 transfection of myoblasts improves the repair of failing myocardium following autologous myoblast transplantation
    Seyedhossein Aharinejad
    Department of Cardio Thoracic Surgery, Medical University of Vienna, Waehringerguertel 18 20, A 1090 Vienna, Austria
    Cardiovasc Res 79:395-404. 2008
  7. doi request reprint Apollon/RNF41 myocardial messenger RNA diagnoses cardiac allograft apoptosis in rejection
    Seyedhossein Aharinejad
    Department of Cardiothoracic Surgery, Medical University of Vienna, Vienna, Austria
    Transplantation 89:245-52. 2010
  8. ncbi request reprint Colony-stimulating factor-1 blockade by antisense oligonucleotides and small interfering RNAs suppresses growth of human mammary tumor xenografts in mice
    Seyedhossein Aharinejad
    Laboratory for Cardiovascular Research, Department of Anatomy and Cell Biology, Vienna Medical University, Waehringerstrasse 13, A 1090 Vienna, Austria
    Cancer Res 64:5378-84. 2004
  9. doi request reprint Donor myocardial apollon mRNA is associated with cardiac allograft rejection
    Seyedhossein Aharinejad
    Department of Cardiac Surgery, Medical University of Vienna, Vienna, Austria
    J Heart Lung Transplant 29:777-85. 2010
  10. ncbi request reprint Differential role of TGF-beta1/bFGF and ET-1 in graft fibrosis in heart failure patients
    Seyedhossein Aharinejad
    Department of Cardio Thoracic Surgery, Vienna Medical University, Waehringer Guertel 18 20, A 1090 Vienna, Austria
    Am J Transplant 5:2185-92. 2005

Collaborators

Detail Information

Publications55

  1. ncbi request reprint Selective upregulation of vascular endothelial growth factor receptors neuropilin-1 and -2 in human neuroblastoma
    Mitra Fakhari
    Department of Pediatric Surgery, University of Vienna, Vienna, Austria
    Cancer 94:258-63. 2002
    ..Neuropilin-1 and 2 (NRP) are novel specific receptors of VEGF(165), whose role is unknown in human neuroblastoma...
  2. doi request reprint First hand accounts of events in the laboratory of Prof. Eduard Pernkopf. Interviews by Seyed Hossein Aharinejad and Stephen W Carmichael
    Walter Kraus
    Center for Anatomy and Cell Biology, Medical University of Vienna, A 1090 Vienna, Austria
    Clin Anat 26:297-303. 2013
    ..We present transcripts of those interviews. The reader may evaluate their recollections in light of the political and social forces active in that period of history...
  3. pmc Serum glutathione S-transferase P1 1 in prediction of cardiac function
    Olena Andrukhova
    Center for Anatomy and Cell Biology, Department of Cardiovascular Research, Vienna, Austria
    J Card Fail 18:253-61. 2012
    ..We hypothesized that GSTP1 might be a useful serum marker in the monitoring of HF patients...
  4. doi request reprint Low serum IGF-1 is a risk factor for cardiac allograft vasculopathy in cardiac transplant recipients
    Seyedhossein Aharinejad
    Department of Cardiac Surgery, Medical University of Vienna, Vienna, Austria
    Transplantation 93:309-13. 2012
    ..Insulin-like growth factor-1 (IGF-1) is associated with different cardiovascular diseases; however, its role in CAV pathogenesis remains unknown...
  5. pmc Association of CD14+ monocyte-derived progenitor cells with cardiac allograft vasculopathy
    Mohamed Salama
    Department of Cardiothoracic Surgery, Center for Anatomy and Cell Biology, Medical University of Vienna, Vienna, Austria
    J Thorac Cardiovasc Surg 142:1246-53. 2011
    ..Endothelial progenitor cells are reportedly involved in cardiac allograft vasculopathy; however, the role of CD14(+) monocyte-derived progenitor cells in cardiac allograft vasculopathy pathogenesis remains unknown...
  6. pmc Colony-stimulating factor-1 transfection of myoblasts improves the repair of failing myocardium following autologous myoblast transplantation
    Seyedhossein Aharinejad
    Department of Cardio Thoracic Surgery, Medical University of Vienna, Waehringerguertel 18 20, A 1090 Vienna, Austria
    Cardiovasc Res 79:395-404. 2008
    ..Colony-stimulating factor-1 (CSF-1) accelerates myoblast proliferation and angiogenesis. We hypothesized that CSF-1 overexpression improves myoblast survival and cardiac function in ischaemia-induced heart failure...
  7. doi request reprint Apollon/RNF41 myocardial messenger RNA diagnoses cardiac allograft apoptosis in rejection
    Seyedhossein Aharinejad
    Department of Cardiothoracic Surgery, Medical University of Vienna, Vienna, Austria
    Transplantation 89:245-52. 2010
    ..The apoptosis rate in EMB correlates with ACR severity. Apollon inhibits apoptosis, and RNF41 catalyzes its degradation. Whether tissue Apollon/RNF41 could diagnose ACR is not known. This study addressed this issue...
  8. ncbi request reprint Colony-stimulating factor-1 blockade by antisense oligonucleotides and small interfering RNAs suppresses growth of human mammary tumor xenografts in mice
    Seyedhossein Aharinejad
    Laboratory for Cardiovascular Research, Department of Anatomy and Cell Biology, Vienna Medical University, Waehringerstrasse 13, A 1090 Vienna, Austria
    Cancer Res 64:5378-84. 2004
    ..In addition, mouse survival significantly increased after CSF-1 blockade. These studies demonstrate that CSF-1 and CSF-1 receptor are potential therapeutic targets for the treatment of mammary cancer...
  9. doi request reprint Donor myocardial apollon mRNA is associated with cardiac allograft rejection
    Seyedhossein Aharinejad
    Department of Cardiac Surgery, Medical University of Vienna, Vienna, Austria
    J Heart Lung Transplant 29:777-85. 2010
    ..ACR is reportedly associated with apoptosis and Apollon inhibits apoptosis and promotes cell survival. It is unknown whether donor myocardial tissue Apollon mRNA could predict ACR...
  10. ncbi request reprint Differential role of TGF-beta1/bFGF and ET-1 in graft fibrosis in heart failure patients
    Seyedhossein Aharinejad
    Department of Cardio Thoracic Surgery, Vienna Medical University, Waehringer Guertel 18 20, A 1090 Vienna, Austria
    Am J Transplant 5:2185-92. 2005
    ..ET-1 might be a major pathologic trigger for graft fibrosis in DCM...
  11. doi request reprint Programmed cell death in idiopathic dilated cardiomyopathy is mediated by suppression of the apoptosis inhibitor Apollon
    Seyedhossein Aharinejad
    Department of Cardiothoracic Surgery, Center of Anatomy and Cell Biology, Medical University of Vienna, Vienna, Austria
    Ann Thorac Surg 86:109-14; discussion 114. 2008
    ..The present study tested the hypothesis that the Apollon/Smac system may mediate programmed cell death in DCM...
  12. doi request reprint Donor serum SMARCAL1 concentrations predict primary graft dysfunction in cardiac transplantation
    Seyedhossein Aharinejad
    Department of Cardiothoracic Surgery, Medical University of Vienna, Austria
    Circulation 120:S198-205. 2009
    ..Primary graft dysfunction (PGD) is a life-threatening complication in cardiac transplantation. A sensitive, specific, and easily measurable predictor in donors could facilitate PGD prevention...
  13. ncbi request reprint Matrix metalloproteases and their tissue inhibitor in cardiac transplantation
    Seyedhossein Aharinejad
    Department of Cardiothoracic Surgery, Medical University of Vienna, Waehringer Guertel 18 20, A 1090 Vienna, Austria
    Eur J Cardiothorac Surg 32:48-51. 2007
    ..This study sought to determine the temporal profile of MMP serum levels following cardiac transplantation...
  14. ncbi request reprint Donor myocardial HIF-1alpha is an independent predictor of cardiac allograft dysfunction: a 7-year prospective, exploratory study
    S Aharinejad
    Department of Cardiothoracic Surgery, Medical University of Vienna, Vienna, Austria
    Am J Transplant 7:2012-9. 2007
    ..HIF-1alpha demonstrates the potential to be a predictive marker for PGD; however, as multiple factors were tested at different time points, prospective evaluation is clearly necessary to confirm this observation...
  15. ncbi request reprint Prediction of lung-transplant rejection by hepatocyte growth factor
    Seyedhossein Aharinejad
    Laboratory for Cardiovascular Research, Department of Anatomy, Medical University of Vienna, Vienna, Austria
    Lancet 363:1503-8. 2004
    ..We investigated whether HGF could be an accurate marker for prediction of lung-graft rejection...
  16. ncbi request reprint Selective downregulation of VEGF-A(165), VEGF-R(1), and decreased capillary density in patients with dilative but not ischemic cardiomyopathy
    D Abraham
    Laboratory for Cardiovascular Research, Department of Anatomy, University of Vienna, Austria
    Circ Res 87:644-7. 2000
    ..Whether downregulation of certain VEGF isoforms in DCM is a cause or consequence of this disorder remains unclear, although upregulated VEGF levels in ICM are most likely the result of ischemia...
  17. doi request reprint Serum matrix metalloprotease-1 and vascular endothelial growth factor--a predict cardiac allograft rejection
    S Aharinejad
    Department of Cardiothoracic Surgery, Center for Anatomy and Cell Biology, Medical University of Vienna, Vienna, Austria
    Am J Transplant 9:149-59. 2009
    ..Combination of serum MMP-1 and VEGF-A concentration may be a noninvasive prognostic marker of cardiac allograft rejection, and could have important implications for choice of surveillance and immunosuppression protocols...
  18. ncbi request reprint Impact of cardiac transplantation on molecular pathology of ET-1, VEGF-C, and mitochondrial metabolism and morphology in dilated versus ischemic cardiomyopathic patients
    S Aharinejad
    Laboratory for Cardiovascular Research, First Department of Anatomy, University of Vienna, Waehringerstrasse 13, A 1090 Vienna, Austria
    Transplantation 72:1043-9. 2001
    ..Therefore, it is more likely that these changes are the cause rather than a consequence of DCM...
  19. doi request reprint Concomitant endothelin-1 overexpression in lung transplant donors and recipients predicts primary graft dysfunction
    M Salama
    Department of Cardiothoracic Surgery, Medical University of Vienna, Vienna, Austria
    Am J Transplant 10:628-36. 2010
    ....
  20. doi request reprint Endothelin-1 is a useful biomarker for early detection of bronchiolitis obliterans in lung transplant recipients
    Mohamed Salama
    Department of Cardiothoracic Surgery, Medical University of Vienna, Vienna, Austria
    J Thorac Cardiovasc Surg 140:1422-7. 2010
    ..Whether ET-1 could predict BO syndrome (BOS) development is unknown...
  21. pmc Stromal cell-derived CSF-1 blockade prolongs xenograft survival of CSF-1-negative neuroblastoma
    Dietmar Abraham
    Laboratory for Cardiovascular Research, Vienna Medical University, A 1090Vienna, Austria
    Int J Cancer 126:1339-52. 2010
    ..These studies demonstrated that increased CSF-1 production by host cells enhances TAM recruitment and NB growth and that the CSF-1 phenotype of NB tumor cells adversely affects survival...
  22. ncbi request reprint Colony-stimulating factor-1 antisense treatment suppresses growth of human tumor xenografts in mice
    Seyedhossein Aharinejad
    Laboratory for Cardiovascular Research, Department of Anatomy, University of Vienna, Waehringerstrasse 13, A 1090 Vienna, Austria
    Cancer Res 62:5317-24. 2002
    ..Because the cancer cells used were CSF-1 negative, CSF-1 antisense targeted tumor stromal cell CSF-1 production. CSF-1 blockade could be a novel strategy in treatment of solid tumors...
  23. ncbi request reprint Vascular endothelial growth factor increases pulmonary vascular permeability in cystic fibrosis patients undergoing lung transplantation
    Katharina Krenn
    Laboratory for Cardiovascular Research, Center for Anatomy and Cell Biology, Medical University of Vienna, Waehringerstr 13, A 1090 Vienna, Austria
    Eur J Cardiothorac Surg 32:35-41. 2007
    ..The mechanisms of VEGF overproduction and its impact on CF lung pathology and pulmonary vascular permeability during lung transplantation are not fully understood...
  24. pmc Elevated transforming growth factor-beta 1 (TGF-β1) levels in human fracture healing
    Kambiz Sarahrudi
    Department of Traumatology, Medical University of Vienna, Waehringer Guertel 18 20, Vienna, Austria
    Injury 42:833-7. 2011
    ..The purpose of this study was to analyse TGF-β1 local and serum concentrations in fracture healing to further contribute to the understanding of molecular regulation of fracture healing...
  25. ncbi request reprint Upregulation of vascular endothelial growth factor receptors is associated with advanced neuroblastoma
    M Fakhari
    Laboratory for Cardiovascular Research, Departments of Anatomy, Pediatric Surgery, and Molecular Biology, University of Vienna, Vienna, Austria
    J Pediatr Surg 37:582-7. 2002
    ..The interaction of VEGF and its receptors at gene and protein levels in neuroblastoma remains widely unknown...
  26. ncbi request reprint Colon cancer cell-derived tumor necrosis factor-alpha mediates the tumor growth-promoting response in macrophages by up-regulating the colony-stimulating factor-1 pathway
    Karin Zins
    Laboratory for Cardiovascular Research, Department of Anatomy and Cell Biology, Vienna Medical University, Waehringerstrasse 13, A 1090 Vienna, Austria
    Cancer Res 67:1038-45. 2007
    ..Thus, interrupting tumor cell-macrophage communication by targeting TNF-alpha may provide an alternative therapeutic approach for the treatment of colon cancer...
  27. ncbi request reprint Impaired VE-cadherin/beta-catenin expression mediates endothelial cell degeneration in dilated cardiomyopathy
    Romana Schäfer
    Laboratory for Cardiovascular Research, Department of Anatomy, University of Vienna, Vienna, Austria
    Circulation 108:1585-91. 2003
    ..Cardiac expression of VEGF-A but not its receptor KDR is blunted in dilated cardiomyopathy (DCM). Whether VE-cadherin/Ang function is affected in DCM is unknown...
  28. ncbi request reprint Host CD147 blockade by small interfering RNAs suppresses growth of human colon cancer xenografts
    Dietmar Abraham
    Laboratory for Cardiovascular Research, Center of Anatomy and Cell Biology, Medical University of Vienna, Waehringerstrasse 13, A 1090 Vienna, Austria
    Front Biosci 13:5571-9. 2008
    ..Interestingly, inhibition of cancer cell-derived EMMPRIN leads to increased MMP-9 levels in vivo. Our findings provide new insights into CD147-mediated tumor-host interactions mediating colon cancer growth...
  29. ncbi request reprint Upregulated hypoxia-inducible factor-1 DNA binding activity to the vascular endothelial growth factor-A promoter mediates increased vascular permeability in donor lung grafts
    Dietmar Abraham
    Laboratory for Cardiovascular Research, Department of Anatomy, University of Vienna, Vienna, Austria
    Ann Thorac Surg 77:1751-5. 2004
    ..We hypothesized that HIF-1 regulates VEGF-mediated vascular permeability in lung grafts...
  30. pmc Adenoviral-mediated endothelial precursor cell delivery of soluble CD115 suppresses human prostate cancer xenograft growth in mice
    Trevor Lucas
    Laboratory for Cardiovascular Research, Department of Anatomy and Cell Biology, Vienna Medical University, Vienna, Austria
    Stem Cells 27:2342-52. 2009
    ..01) and vascular density (p < .03), and suppresses the growth of xenografts (p < .03). These data show for the first time that targeting stromal cell processes with cellular therapy has the potential to retard prostate tumor growth...
  31. ncbi request reprint Colony-stimulating factor-1 antibody reverses chemoresistance in human MCF-7 breast cancer xenografts
    Patrick Paulus
    Laboratory for Cardiovascular Research, Department of Anatomy and Cell Biology, Vienna Medical University, Vienna, Austria
    Cancer Res 66:4349-56. 2006
    ..These studies support the paradigm of CSF-1 blockade in the treatment of solid tumors and show that anti-CSF-1 antibodies are potential therapeutic agents for the treatment of mammary cancer...
  32. ncbi request reprint Recipient vascular endothelial growth factor serum levels predict primary lung graft dysfunction
    K Krenn
    Laboratory for Cardiovascular Research, Center for Anatomy and Cell Biology, Medical University of Vienna, Waehringerstrasse 13, A 1090 Vienna, Austria
    Am J Transplant 7:700-6. 2007
    ..778). At a cut-off level of > or =650 pg/mL VEGF had 86% sensitivity and 62% specificity to identify PGD grade 3 versus 0-2. Pre-operative VEGF serum concentrations could identify lung transplant recipients with high PGD risk...
  33. ncbi request reprint Broncho-alveolar lavage matrix metalloproteases as a sensitive measure of bronchiolitis obliterans
    Shahrokh Taghavi
    Department of Cardio Thoracic Surgery, Vienna Medical University, Waehringer Guertel, Austria
    Am J Transplant 5:1548-52. 2005
    ..BAL MMP-8, -9 and TIMP-1 might be useful markers to detect BO in lung transplant patients...
  34. doi request reprint Direct epicardial shock wave therapy improves ventricular function and induces angiogenesis in ischemic heart failure
    Daniel Zimpfer
    Department of Cardiothoracic Surgery, Medical University of Vienna, Vienna, Austria
    J Thorac Cardiovasc Surg 137:963-70. 2009
    ..Direct application of low-energy unfocused shock waves induces angiogenesis in ischemic soft tissue. The potential effects of epicardial shock wave therapy applied in direct contact to ischemic myocardium are uncertain...
  35. doi request reprint Novel insights into the mechanisms and treatment of intramural hematoma affecting the entire thoracic aorta
    Michael Grimm
    Department of Cardiothoracic Surgery, University of Vienna Medical School, Vienna, Austria
    Ann Thorac Surg 86:453-6. 2008
    ....
  36. ncbi request reprint Inflammation and postinfarct remodeling: overexpression of IkappaB prevents ventricular dilation via increasing TIMP levels
    Karola Trescher
    Ludwig Boltzmann Institute for Cardiosurgical Research, Medical University of Vienna, c o Institute of Biomedical Research, AKH Wien, Wahringer Gurtel 18 20, 1090 Vienna, Austria
    Cardiovasc Res 69:746-54. 2006
    ..The objective of the present study was to investigate the effect of overexpression and mode of function of IkappaB, the natural inhibitor of NF-kappaB, on ECM remodeling in a rat model of MI...
  37. doi request reprint Targeting stromal-cancer cell interactions with siRNAs
    Seyedhossein Aharinejad
    Laboratory for Cardiovascular Research, Center for Anatomy and Cell Biology, Medical University of Vienna, Vienna, Austria
    Methods Mol Biol 487:243-66. 2009
    ..This chapter summarizes our current understanding of the tumor microenvironment and highlights some potential targets for therapeutic intervention with small interfering RNAs...
  38. ncbi request reprint Target validation using RNA interference in solid tumors
    Seyedhossein Aharinejad
    Laboratory for Cardiovascular Research, Center for Anatomy and Cell Biology, Vienna Medical University, Vienna, Austria
    Methods Mol Biol 361:227-38. 2007
    ..The suppression of CSF-1 by RNA interference is therefore a powerful tool to block gene function and influence tumor-stroma interactions in solid tumor development...
  39. ncbi request reprint Co-expression of endothelin-1 and vascular endothelial growth factor mediates increased vascular permeability in lung grafts before reperfusion
    Shahrokh Taghavi
    Department of Cardiothoracic Surgery, University of Vienna, Vienna, Austria
    J Heart Lung Transplant 21:600-3. 2002
    ..Hypoxia and ET-1 co-upregulate VEGF-A overexpression, therefore temporary VEGF-A antagonism during graft preservation might be of benefit in lung transplantation...
  40. doi request reprint Growth factor release in extra- and intramedullary osteosynthesis following tibial fracture
    K Sarahrudi
    Department of Traumatology, Medical University of Vienna, Waehringer Guertel 18 20, Vienna, Austria
    Injury 42:772-7. 2011
    ..The purpose of the study was to investigate whether different osteosynthesis techniques influence the released quantity of cytokines...
  41. doi request reprint VEGF serum concentrations in patients with long bone fractures: a comparison between impaired and normal fracture healing
    Kambiz Sarahrudi
    Department of Traumatology, Medical University of Vienna, Waehringer Guertel 18 20, A 1090 Vienna, Austria
    J Orthop Res 27:1293-7. 2009
    ....
  42. doi request reprint Combination of anorganic bovine-derived hydroxyapatite with binding peptide does not enhance bone healing in a critical-size defect in a rabbit model
    Kambiz Sarahrudi
    Department of Traumatology, Medical University of Vienna, Vienna, Austria
    J Orthop Res 26:759-63. 2008
    ..0004). An enhanced or accelerated ingrowth of bone, as reported in previous studies, was not observed. Our results imply that the ABM/P-15 is not a suitable graft for the treatment of critical-sized segmental defects in long bones...
  43. ncbi request reprint Pulmonary lymphatic filling is increased in spontaneously hypertensive rats
    S Aharinejad
    Microcirculation Laboratory, Department of Anatomy, University of Vienna, Wahringerstrasse 13, A 1090 Vienna, Austria
    Anat Embryol (Berl) 200:425-32. 1999
    ..01). This anatomic evidence suggests that pulmonary venous sphincters are associated with focal lymphatic filling, and perivascular muscle action might be a component of the pulmonary lymphatic system...
  44. ncbi request reprint Valvular density alone cannot account for sites of chronic venous insufficiency and ulceration in the lower extremity
    S Aharinejad
    Laboratory for Cardiovascular Research, Department of Anatomy, University of Vienna, Vienna, Austria
    Microcirculation 8:347-54. 2001
    ..We hypothesized that the anatomical distribution of venous stasis ulcers in the lower extremity is related to a lower density of venous valves...
  45. ncbi request reprint Morphometry of human coronary arterial trees
    S Aharinejad
    Department of Anatomy, University of Vienna, Austria
    Anat Rec 251:50-9. 1998
    ..Arterial trees have been grown to arbitrary resolution without input of anatomical data. We performed this study to learn about the shortcomings that might have resulted from neglecting the anatomical data in CCO models...
  46. ncbi request reprint VEGF-A and -C but not -B mediate increased vascular permeability in preserved lung grafts
    Dietmar Abraham
    Laboratory for Cardiovascular Research, First Department of Anatomy, University of Vienna, Waehringerstrasse 13, A 1090 Vienna, Austria
    Transplantation 73:1703-6. 2002
    ..Overexpression of VEGF is associated with increased vascular permeability in the early stage of acute lung injury in mice. The role of various forms of VEGF in transplantation-induced lung injury is not well understood...
  47. doi request reprint Persistent plasminogen activator inhibitor 1 gene expression in cardiac transplant recipients with idiopathic dilated cardiomyopathy
    Romana Schäfer
    Laboratory for Cardiovascular Research, Center for Anatomy and Cell Biology, Medical University of Vienna, A 1090 Vienna, Austria
    J Thorac Cardiovasc Surg 139:1644-51. 2010
    ..Idiopathic dilated cardiomyopathy is reportedly associated with endothelial cell dysfunction. Whether endothelial cell damage plays a role in patients with dilated cardiomyopathy after cardiac transplantation remains unknown...
  48. ncbi request reprint Low dose carboplatin combined with angiostatic agents prevents metastasis in human testicular germ cell tumor xenografts
    Dietmar Abraham
    Department of Anatomy, University of Vienna, Austria
    J Urol 170:1388-93. 2003
    ..We examined the efficacy of angiostatic thrombospondin-1 (TSP-1), endostatin and combined angiostatic/low dose carboplatin in mice xenografted with human nonseminomatous germ cell tumor...
  49. doi request reprint Elevated levels of macrophage colony-stimulating factor in human fracture healing
    Kambiz Sarahrudi
    Department of Traumatology, Medical University of Vienna, and Department of Traumatology and Sportstraumatology, Danube Hospital, Vienna, Austria
    J Orthop Res 28:671-6. 2010
    ..This study indicates, for the first time, to our knowledge, a possible local and systemic involvement of M-CSF in humans during fracture healing...
  50. ncbi request reprint Fibrin-embedded administration of VEGF plasmid enhances skin flap survival
    Wolfgang Michlits
    Laboratory for Cardiovascular Research, Center for Anatomy and Cell Biology, Medical University of Vienna, Vienna, Austria
    Wound Repair Regen 15:360-7. 2007
    ..The suggested therapeutic approach is easily applicable and inexpensive in preparation. Thus, this protocol may also enhance wound healing in posttrauma skin lacerations or in skin grafts...
  51. ncbi request reprint Modulation of tumor associated macrophages in solid tumors
    Trevor Lucas
    Laboratory for Cardiovascular Research, Center for Anatomy and Cell Biology, Vienna Medical University, Waehringer Strasse 13, Vienna, A 1090, Austria
    Front Biosci 13:5580-8. 2008
    ..This review outlines the strategies for targeting CSF-1 in malignancies to influence TAMs in tumor development...
  52. doi request reprint Prophylactic low-energy shock wave therapy improves wound healing after vein harvesting for coronary artery bypass graft surgery: a prospective, randomized trial
    Julia Dumfarth
    Department of Cardiothoracic Surgery, Medical University of Vienna, Austria
    Ann Thorac Surg 86:1909-13. 2008
    ..In this study, we investigate whether prophylactic low-energy SWT improves wound healing after vein harvesting for coronary artery bypass graft surgery...
  53. doi request reprint The impact of colony-stimulating factor-1 on fracture healing: an experimental study
    Kambiz Sarahrudi
    Department of Traumatology, Medical University of Vienna, Vienna, Austria
    J Orthop Res 27:36-41. 2009
    ..The present data emphasize for the first time the importance of CSF-1 in the bone healing. The use of CSF-1 in addition to conventional fixation might be a novel approach for the treatment of bone defects...
  54. ncbi request reprint Structural aspects of the lymphocyte traffic in rat submandibular lymph node
    Shigenori Okada
    Section of Respiratory and Critical Care Medicine, Department of Medicine, University of Illinois at Chicago, 840 S Wood St, Chicago, IL 60612 7323, USA
    Microsc Microanal 8:116-33. 2002
    ..However, the highly organized structural organization may play a significant role in regulating and directing lymphocyte flow to facilitate antigen presentation...
  55. ncbi request reprint Arteriogenesis depends on circulating monocytes and macrophage accumulation and is severely depressed in op/op mice
    Caroline E Bergmann
    Research Group for Experimental and Clinical Arteriogenesis, Freiberg, Germany
    J Leukoc Biol 80:59-65. 2006
    ..This study provides additional evidence for the preeminent role of monocytes/macrophages during arteriogenesis in a genuine model of monocyte deficiency, i.e., without pharmacological intervention...