W Wirth

Summary

Affiliation: Institute of Anatomy and Musculoskeletal Research
Country: Austria

Publications

  1. pmc Meniscus body position and its change over four years in asymptomatic adults: a cohort study using data from the Osteoarthritis Initiative (OAI)
    Katharina Bruns
    Department of Orthopedics, Clinical Sciences Lund, Lund University, Lund, Sweden
    BMC Musculoskelet Disord 15:32. 2014
  2. pmc Lateral and medial joint space narrowing predict subsequent cartilage loss in the narrowed, but not in the non-narrowed femorotibial compartment--data from the Osteoarthritis Initiative
    W Wirth
    Institute of Anatomy and Musculoskeletal Research, Paracelsus Medical University, Salzburg, Austria Chondrometrics GmbH, Ainring, Germany Electronic address
    Osteoarthritis Cartilage 22:63-70. 2014
  3. pmc Direct comparison of fixed flexion, radiography and MRI in knee osteoarthritis: responsiveness data from the Osteoarthritis Initiative
    W Wirth
    Institute of Anatomy and Musculoskeletal Research, Paracelsus Medical University, Salzburg, Austria
    Osteoarthritis Cartilage 21:117-25. 2013
  4. pmc Revision 1 size and position of the healthy meniscus, and its correlation with sex, height, weight, and bone area- a cross-sectional study
    Katja Bloecker
    Institute of Anatomy and Musculoskeletal Research, Paracelsus Medical University Salzburg, Austria
    BMC Musculoskelet Disord 12:248. 2011
  5. pmc Comparison of 1-year vs 2-year change in regional cartilage thickness in osteoarthritis results from 346 participants from the Osteoarthritis Initiative
    W Wirth
    Institute of Anatomy and Musculoskeletal Research, Paracelsus Medical University, Salzburg, Austria
    Osteoarthritis Cartilage 19:74-83. 2011
  6. pmc Sensitivity to change of cartilage morphometry using coronal FLASH, sagittal DESS, and coronal MPR DESS protocols--comparative data from the Osteoarthritis Initiative (OAI)
    W Wirth
    Chondrometrics GmbH, Ainring, Germany
    Osteoarthritis Cartilage 18:547-54. 2010
  7. pmc MRI-based extended ordered values more efficiently differentiate cartilage loss in knees with and without joint space narrowing than region-specific approaches using MRI or radiography--data from the OA initiative
    W Wirth
    Chondrometrics GmbH, Ainring, Germany
    Osteoarthritis Cartilage 19:689-99. 2011
  8. ncbi request reprint Relationship between knee pain and the presence, location, size and phenotype of femorotibial denuded areas of subchondral bone as visualized by MRI
    S Cotofana
    Paracelsus Medical University, Salzburg, Austria
    Osteoarthritis Cartilage 21:1214-22. 2013
  9. pmc Regional analysis of femorotibial cartilage loss in a subsample from the Osteoarthritis Initiative progression subcohort
    W Wirth
    Chondrometrics GmbH, Ainring, Germany
    Osteoarthritis Cartilage 17:291-7. 2009
  10. pmc Presence, location, type and size of denuded areas of subchondral bone in the knee as a function of radiographic stage of OA - data from the OA initiative
    R B Frobell
    Institute of Anatomy and Musculoskeletal Research, Paracelsus Medical University, Salzburg, Austria
    Osteoarthritis Cartilage 18:668-76. 2010

Collaborators

Detail Information

Publications31

  1. pmc Meniscus body position and its change over four years in asymptomatic adults: a cohort study using data from the Osteoarthritis Initiative (OAI)
    Katharina Bruns
    Department of Orthopedics, Clinical Sciences Lund, Lund University, Lund, Sweden
    BMC Musculoskelet Disord 15:32. 2014
    ..However, very little is known about meniscal position in the asymptomatic knee and its natural history. Hence our objective was to study meniscal body position and its change over 4 years in asymptomatic adults...
  2. pmc Lateral and medial joint space narrowing predict subsequent cartilage loss in the narrowed, but not in the non-narrowed femorotibial compartment--data from the Osteoarthritis Initiative
    W Wirth
    Institute of Anatomy and Musculoskeletal Research, Paracelsus Medical University, Salzburg, Austria Chondrometrics GmbH, Ainring, Germany Electronic address
    Osteoarthritis Cartilage 22:63-70. 2014
    ..To determine the predictive value of unicompartimental joint space narrowing (JSN) for MRI-based cartilage thickness loss in the narrowed and the non-narrowed femorotibial compartment...
  3. pmc Direct comparison of fixed flexion, radiography and MRI in knee osteoarthritis: responsiveness data from the Osteoarthritis Initiative
    W Wirth
    Institute of Anatomy and Musculoskeletal Research, Paracelsus Medical University, Salzburg, Austria
    Osteoarthritis Cartilage 21:117-25. 2013
    ..We directly compare the responsiveness of magnetic resonance imaging (MRI)-based cartilage thickness and JSW measures from fixed-flexion radiography (FFR) and explore the correlation of region-matched changes between both methods...
  4. pmc Revision 1 size and position of the healthy meniscus, and its correlation with sex, height, weight, and bone area- a cross-sectional study
    Katja Bloecker
    Institute of Anatomy and Musculoskeletal Research, Paracelsus Medical University Salzburg, Austria
    BMC Musculoskelet Disord 12:248. 2011
    ..Meniscus extrusion or hypertrophy may occur in knee osteoarthritis (OA). However, currently no data are available on the position and size of the meniscus in asymptomatic men and women with normal meniscus integrity...
  5. pmc Comparison of 1-year vs 2-year change in regional cartilage thickness in osteoarthritis results from 346 participants from the Osteoarthritis Initiative
    W Wirth
    Institute of Anatomy and Musculoskeletal Research, Paracelsus Medical University, Salzburg, Austria
    Osteoarthritis Cartilage 19:74-83. 2011
    ..To compare femorotibial cartilage thickness changes over a 2- vs a 1-year observation period in knees with radiographic knee osteoarthritis (OA)...
  6. pmc Sensitivity to change of cartilage morphometry using coronal FLASH, sagittal DESS, and coronal MPR DESS protocols--comparative data from the Osteoarthritis Initiative (OAI)
    W Wirth
    Chondrometrics GmbH, Ainring, Germany
    Osteoarthritis Cartilage 18:547-54. 2010
    ..We therefore directly compared the sensitivity to cartilage thickness changes and the correlation of these protocols longitudinally...
  7. pmc MRI-based extended ordered values more efficiently differentiate cartilage loss in knees with and without joint space narrowing than region-specific approaches using MRI or radiography--data from the OA initiative
    W Wirth
    Chondrometrics GmbH, Ainring, Germany
    Osteoarthritis Cartilage 19:689-99. 2011
    ....
  8. ncbi request reprint Relationship between knee pain and the presence, location, size and phenotype of femorotibial denuded areas of subchondral bone as visualized by MRI
    S Cotofana
    Paracelsus Medical University, Salzburg, Austria
    Osteoarthritis Cartilage 21:1214-22. 2013
    ..A relation between pain and denuded areas of subchondral bone (dABs) has been suggested and this study explores this relationship further by relating the presence, phenotype, location and size of dABs to different measures of knee pain...
  9. pmc Regional analysis of femorotibial cartilage loss in a subsample from the Osteoarthritis Initiative progression subcohort
    W Wirth
    Chondrometrics GmbH, Ainring, Germany
    Osteoarthritis Cartilage 17:291-7. 2009
    ..Here we analyze regional femorotibial (FT) cartilage thickness changes over 1 year using 3 Tesla MRI. Specifically, we tested whether changes in central subregions exceed those in the total cartilage plates...
  10. pmc Presence, location, type and size of denuded areas of subchondral bone in the knee as a function of radiographic stage of OA - data from the OA initiative
    R B Frobell
    Institute of Anatomy and Musculoskeletal Research, Paracelsus Medical University, Salzburg, Austria
    Osteoarthritis Cartilage 18:668-76. 2010
    ..To assess the presence, location, type and size of denuded areas of subchondral bone (dAB) in the femorotibial joint, measured quantitatively with 3T MRI, in a large subset of OAI participants...
  11. ncbi request reprint Tibial coverage, meniscus position, size and damage in knees discordant for joint space narrowing - data from the Osteoarthritis Initiative
    K Bloecker
    Institute for Anatomy and Musculoskeletal Research, Paracelsus Medical University, Salzburg, Austria
    Osteoarthritis Cartilage 21:419-27. 2013
    ..We therefore compared quantitative and semi-quantitative measures of meniscus position and morphology in individuals with bilateral painful knees discordant on medial joint space narrowing (mJSN)...
  12. pmc How do short-term rates of femorotibial cartilage change compare to long-term changes? Four year follow-up data from the osteoarthritis initiative
    F Eckstein
    Institute of Anatomy and Musculoskeletal Research, Paracelsus Medical University, Salzburg, Austria
    Osteoarthritis Cartilage 20:1250-7. 2012
    ..To compare unbiased estimates of short- vs long-term cartilage loss in osteoarthritic knees...
  13. ncbi request reprint Effects of exercise intervention on knee morphology in middle-aged women: a longitudinal analysis using magnetic resonance imaging
    S Cotofana
    Institute of Anatomy and Musculoskeletal Research, Paracelsus Medical University, Salzburg, Austria sebastian cotofana pmu ac at
    Cells Tissues Organs 192:64-72. 2010
    ....
  14. ncbi request reprint Femorotibial cartilage morphology: reproducibility of different metrics and femoral regions, and sensitivity to change in disease
    M Hudelmaier
    Institute of Anatomy and Musculoskeletal Research, Paracelsus Medical University, Salzburg, Austria
    Cells Tissues Organs 192:340-50. 2010
    ..35). The long femoral cartilage ROI provided more reproducible measurements than the short one. VCtAB and ThCtAB.Me may be preferable metrics in longitudinal studies of articular cartilage adaptation or OA...
  15. pmc Reference values and Z-scores for subregional femorotibial cartilage thickness--results from a large population-based sample (Framingham) and comparison with the non-exposed Osteoarthritis Initiative reference cohort
    F Eckstein
    Paracelsus Medical University and Chondrometrics GmbH, Salzburg, Austria
    Osteoarthritis Cartilage 18:1275-83. 2010
    ..To establish sex-specific (subregional) reference values of cartilage thickness and potential maximal Z-scores in the femorotibial joint...
  16. pmc Baseline and longitudinal change in isometric muscle strength prior to radiographic progression in osteoarthritic and pre-osteoarthritic knees--data from the Osteoarthritis Initiative
    F Eckstein
    Institute of Anatomy and Musculoskeletal Research, Paracelsus Medical University, A5020 Salzburg, Austria
    Osteoarthritis Cartilage 21:682-90. 2013
    ....
  17. pmc One year change of knee cartilage morphology in the first release of participants from the Osteoarthritis Initiative progression subcohort: association with sex, body mass index, symptoms and radiographic osteoarthritis status
    F Eckstein
    Institute of Anatomy and Musculoskeletal Research, PMU, Salzburg, Austria
    Ann Rheum Dis 68:674-9. 2009
    ..Here cartilage loss using 3 Tesla (3 T) MRI is analysed over 1 year in a subset of the OAI, together with its association with various risk factors...
  18. ncbi request reprint Contribution of regional 3D meniscus and cartilage morphometry by MRI to joint space width in fixed flexion knee radiography--a between-knee comparison in subjects with unilateral joint space narrowing
    K Bloecker
    Institute of Anatomy and Musculoskeletal Research, Paracelsus Medical University, Strubergasse 21, 5020 Salzburg, Austria Department of Traumatology and Sports Medicine, Paracelsus Medical University, Mullner Hauptstrasse 48, 5020 Salzburg, Austria Electronic address
    Eur J Radiol 82:e832-9. 2013
    ..Our objective was to determine the proportion by which 3D (regional) meniscus and cartilage measures explain between-knee differences of JSW in the fixed flexion radiographs...
  19. pmc Double echo steady state magnetic resonance imaging of knee articular cartilage at 3 Tesla: a pilot study for the Osteoarthritis Initiative
    F Eckstein
    Institute of Anatomy and Musculoskeletal Research, Paracelsus Private Medical University, Strubergasse 21, A5020 Salzburg, Austria
    Ann Rheum Dis 65:433-41. 2006
    ..Quantitative magnetic resonance imaging (qMRI) may provide valuable measures of cartilage morphology in osteoarthritis (OA) but has been confined to sequences with relatively long acquisition times at 1.5 Tesla (T)...
  20. ncbi request reprint Relative distribution of quadriceps head anatomical cross-sectional areas and volumes-Sensitivity to pain and to training intervention
    M Sattler
    Institute of Anatomy, Paracelsus Medical University, Salzburg, Austria
    Ann Anat 196:464-70. 2014
    ..This is the first study to explore the relative distribution of quadriceps head anatomical cross-sectional areas (ACSA) and volumes, and their response to pain and to training intervention...
  21. ncbi request reprint Thigh muscle cross-sectional areas and strength in knees with early vs knees without radiographic knee osteoarthritis: a between-knee, within-person comparison
    A S Ruhdorfer
    Institute of Anatomy, Paracelsus Medical University, Salzburg, Austria Electronic address
    Osteoarthritis Cartilage 22:1634-8. 2014
    ....
  22. ncbi request reprint Trajectory of cartilage loss within 4 years of knee replacement--a nested case-control study from the Osteoarthritis Initiative
    F Eckstein
    Institute of Anatomy, Paracelsus Medical University, Salzburg, Austria Chondrometrics GmbH, Ainring, Germany Electronic address
    Osteoarthritis Cartilage 22:1542-9. 2014
    ..Knee replacement (KR) represents a clinically important endpoint of knee osteoarthritis (KOA). Here we examine the 4-year trajectory of femoro-tibial cartilage thickness loss prior to KR vs non-replaced controls...
  23. pmc Side differences of thigh muscle cross-sectional areas and maximal isometric muscle force in bilateral knees with the same radiographic disease stage, but unilateral frequent pain - data from the osteoarthritis initiative
    M Sattler
    Institute of Anatomy and Musculoskeletal Research, Paracelsus Medical University, Salzburg, Austria
    Osteoarthritis Cartilage 20:532-40. 2012
    ....
  24. ncbi request reprint Is loss in femorotibial cartilage thickness related to severity of contra-lateral radiographic knee osteoarthritis? - Longitudinal data from the Osteoarthritis Initiative
    S Cotofana
    Institute of Anatomy, Paracelsus Medical University, Salzburg, Austria Chondrometrics GmbH, Ainring, Germany Electronic address
    Osteoarthritis Cartilage 22:2059-66. 2014
    ..Here we analyze a "progression" model in mild radiographic KOA (RKOA), based on contra-lateral radiographic status...
  25. ncbi request reprint Imaging of cartilage and bone: promises and pitfalls in clinical trials of osteoarthritis
    F Eckstein
    Institute of Anatomy, Paracelsus Medical University, Salzburg, Austria Chondrometrics GmbH, Ainring, Germany Electronic address
    Osteoarthritis Cartilage 22:1516-32. 2014
    ..When employed properly, imaging has tremendous potential for ascertaining treatment effects on various joint structures, potentially over shorter time scales than required for demonstrating effects on clinical outcomes. ..
  26. pmc Magnitude and regional distribution of cartilage loss associated with grades of joint space narrowing in radiographic osteoarthritis--data from the Osteoarthritis Initiative (OAI)
    F Eckstein
    Institute of Anatomy, PMU Salzburg, Austria
    Osteoarthritis Cartilage 18:760-8. 2010
    ....
  27. ncbi request reprint Rates and sensitivity of knee cartilage thickness loss in specific central reading radiographic strata from the Osteoarthritis Initiative
    S Maschek
    Institute of Anatomy, Paracelsus Medical University, Salzburg, Austria Chondrometrics GmbH, Ainring, Germany
    Osteoarthritis Cartilage 22:1550-3. 2014
    ....
  28. ncbi request reprint Longitudinal analysis of MR spin-spin relaxation times (T2) in medial femorotibial cartilage of adolescent vs mature athletes: dependence of deep and superficial zone properties on sex and age
    W Wirth
    Institute of Anatomy, Paracelsus Medical University, Salzburg, Austria
    Osteoarthritis Cartilage 22:1554-8. 2014
    ..However, no longitudinal imaging studies have been conducted to examine cartilage maturation in healthy subjects thus far. Therefore, we explore T2 change in the deep and superficial cartilage layers at the end of adolescence...
  29. ncbi request reprint Five-year followup of knee joint cartilage thickness changes after acute rupture of the anterior cruciate ligament
    F Eckstein
    Institute of Anatomy, Paracelsus Medical University, Salzburg and Nuremberg, Salzburg, Austria, and Chondrometrics GmbH, Ainring, Germany
    Arthritis Rheumatol 67:152-61. 2015
    ..Anterior cruciate ligament (ACL) rupture involves an increased risk of osteoarthritis. The purpose of this study was to explore changes in cartilage thickness over 5 years after ACL rupture...
  30. pmc Morphometric differences between the medial and lateral meniscus in healthy men - a three-dimensional analysis using magnetic resonance imaging
    K Bloecker
    Institute of Anatomy and Musculoskeletal Research, Paracelsus Medical University, Salzburg, Austria
    Cells Tissues Organs 195:353-64. 2012
    ..001) than the medial one. Also, the LM displayed less (physiological) extrusion than the medial one. These data may guide strategies for meniscal tissue engineering and transplantation aiming to restore normal joint conditions...
  31. ncbi request reprint Correlation between single-slice muscle anatomical cross-sectional area and muscle volume in thigh extensors, flexors and adductors of perimenopausal women
    S Cotofana
    Institute of Anatomy and Musculoskeletal Research, Paracelsus Private Medical University, Strubergasse 21, 5020 Salzburg, Austria
    Eur J Appl Physiol 110:91-7. 2010
    ....