Research Topics
Genomes and GenesSpecies | William SterlacciSummaryAffiliation: Innsbruck Medical University Country: Austria Publications
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Detail Information
Publications
Thyroid follicular carcinoma-like renal tumor: a case report with morphologic, immunophenotypic, cytogenetic, and scintigraphic studiesWilliam Sterlacci
Department of Pathology, Medical University of Innsbruck, Muellerstr 44, Innsbruck, Austria
Virchows Arch 452:91-5. 2008..To our knowledge, this is the second fully documented case of a thyroid follicular carcinoma-like renal tumor. This uncommon variant is important to keep in mind to prevent unnecessary or inappropriate treatment...
Idiopathic systemic amyloidosis primarily affecting the lungs with fatal pulmonary haemorrhage due to vascular involvementWilliam Sterlacci
Institute of Pathology, Medical University of Innsbruck, Mullerstrasse 44, 6020, Innsbruck, Austria
Pathol Oncol Res 15:133-6. 2009..The diagnosis was established after fatal pulmonary haemorrhage caused by vessel impairment due to additional vascular amyloid deposits...
Clinical relevance of neuroendocrine differentiation in non-small cell lung cancer assessed by immunohistochemistry: a retrospective study on 405 surgically resected casesWilliam Sterlacci
Institute for Pathology, Medical University Innsbruck, Muellerstrasse 44, 6020 Innsbruck, Austria
Virchows Arch 455:125-32. 2009..In conclusion, additional immunohistochemical detection of neuroendocrine differentiation in non-small cell lung cancer is presently not of prognostic importance and does not justify a distinct consideration...
Tissue-sparing application of the newly proposed IASLC/ATS/ERS classification of adenocarcinoma of the lung shows practical diagnostic and prognostic impactWilliam Sterlacci
Academic Hospital Feldkirch, Affiliation of the Medical University Innsbruck, Institute for Pathology, Carinagasse 47, 6807 Feldkirch, Austria
Am J Clin Pathol 137:946-56. 2012..5 months; for poor differentiation, 38.5 months; P = .019). Double stains combining the aforementioned nuclear and membranous markers are highly diagnostic for NSCLC, conserving tumor tissue for subsequent analyses...
High transforming growth factor β expression represents an important prognostic parameter for surgically resected non-small cell lung cancerWilliam Sterlacci
University Teaching Hospital Feldkirch, Institute for Pathology, Carinagasse 47, 6807 Feldkirch, Austria
Hum Pathol 43:339-49. 2012..021; hazard ratio, 2.602; 95% confidence interval, 1.159-5.844). These results should help to identify patients who are most suitable for therapeutic strategies aiming to block the transforming growth factor β signaling pathway...
A comprehensive analysis of p16 expression, gene status, and promoter hypermethylation in surgically resected non-small cell lung carcinomasWilliam Sterlacci
Institute for Pathology, Academic Teaching Hospital Feldkirch, Affiliation of the Medical University Innsbruck, Carinagasse, Feldkirch, Austria
J Thorac Oncol 6:1649-57. 2011..Further insight into the significance of protein expression, gene status and promoter methylation is needed and has the potential to optimize existing treatment strategies...
The prognostic impact of sex on surgically resected non-small cell lung cancer depends on clinicopathologic characteristicsWilliam Sterlacci
Institute for Pathology, Academic Hospital Feldkirch, Affiliation of the Medical University Innsbruck, Feldkirch, Austria
Am J Clin Pathol 135:611-8. 2011..This study elucidates sex-specific interactions between patient and tumor characteristics, which are pivotal toward improving prognostic accuracy, individualized therapies, and screening efforts...
Deregulation of p27 and cyclin D1/D3 control over mitosis is associated with unfavorable prognosis in non-small cell lung cancer, as determined in 405 operated patientsWilliam Sterlacci
Hospital Feldkirch, Affiliation of the Medical University Innsbruck, Institute for Pathology, Carinagasse 47, Feldkirch, Austria
J Thorac Oncol 5:1325-36. 2010....
The elderly patient with surgically resected non-small cell lung cancer--a distinct situation?William Sterlacci
University Teaching Hospital Feldkirch, Institute for Pathology, Carinagasse 47, 6807 Feldkirch, Austria
Exp Gerontol 47:237-42. 2012..The Ki-67 index offers prognostic information for overall survival in the elderly...
Basic clinical parameters predict gefitinib efficacy in non-small cell lung cancerAndreas Pircher
Medical University of Innsbruck, Department of Internal Medicine V Haematology and Oncology, Anichstrasse 35, A 6020 Innsbruck, Austria
Anticancer Res 31:2949-55. 2011..We retrospectively analysed data for 82 patients with advanced NSCLC treated with gefitinib and correlated benefits with clinical baseline and therapy-related parameters...
Absence of extramural venous invasion is an excellent predictor of metastasis-free survival in colorectal carcinoma stage II--a study using tangential tissue sectioningKlaus Dirschmid
Institute for Pathology, Academic Teaching Hospital Feldkirch, Feldkirch, Austria
J Clin Pathol 65:619-23. 2012..The present prospective study applies tangential vessel preparation to CRC resection specimens and correlates results of EVI with metachronous haematogenous metastatic (MHM) spread...
Prognostic and predictive value of cell cycle deregulation in non-small-cell lung cancerWilliam Sterlacci
Institute of Pathology, Feldkirch Academic Hospital, Affiliation of the Innsbruck Medical University, Feldkirch, Austria
Pathobiology 79:175-94. 2012..In conclusion, the cell cycle offers several prognostic, predictive and therapeutic possibilities in NSCLC, many still developmental. Progress in this field has the potential to improve the current scenario for NSCLC patients...
Splenic rupture, beyond and behind: a histological, morphometric and follow-up study of 254 casesWilliam Sterlacci
Institute of Pathology, Medical University of Innsbruck, Innsbruck, Austria
Pathobiology 73:280-7. 2006..CONCLUSIONS: Splenic rupture is due to an often unexpected underlying disease in approximately 10% of the cases. This should be kept in mind when dealing with susceptible patient groups...
Angiogenesis in nodal B cell lymphomas: a high throughput studyAlexandar Tzankov
Institute of Pathology, Medical University of Innsbruck, Innsbruck, Austria
J Clin Pathol 60:476-82. 2007....
Implications of EGFR PharmDx kit for cetuximab eligibilityChristian Ensinger
Institute of Pathology, Medical University of Innsbruck, A 6020 Innsbruck, Austria
Expert Rev Mol Diagn 8:141-8. 2008..This proceeding represents an important step toward a personalized cancer therapy with major advantages for patients, mainly reduction of toxic side effects and dramatically increased efficiency...
Paclitaxel treatment reduces neointimal hyperplasia in cultured human saphenous veinsThomas Schachner
Department of Cardiac Surgery, Innsbruck Medical University, Innsbruck, Austria
Eur J Cardiothorac Surg 32:906-11. 2007....
