Claudia Lamina

Summary

Affiliation: Innsbruck Medical University
Country: Austria

Publications

  1. pmc Digging into the extremes: a useful approach for the analysis of rare variants with continuous traits?
    Claudia Lamina
    Division of Genetic Epidemiology, Department of Medical Genetics, Molecular, and Clinical Pharmacology, Innsbruck Medical University, Schopfstrasse 41, 6020 Innsbruck, Austria
    BMC Proc 5:S105. 2011
  2. doi request reprint Visualizing interaction effects: a proposal for presentation and interpretation
    Claudia Lamina
    Division of Genetic Epidemiology, Department of Medical Genetics, Molecular and Clinical Pharmacology, Innsbruck Medical University, Schöpfstr 41, A 6020 Innsbruck, Austria
    J Clin Epidemiol 65:855-62. 2012
  3. pmc Interaction of time-varying albumin and phosphorus on mortality in incident dialysis patients
    Emanuel Zitt
    Department of Nephrology and Dialysis, Academic Teaching Hospital, Feldkirch, Austria
    Clin J Am Soc Nephrol 6:2650-6. 2011
  4. pmc Association of HbA1c values with mortality and cardiovascular events in diabetic dialysis patients. The INVOR study and review of the literature
    Gisela Sturm
    Division of Genetic Epidemiology, Department of Medical Genetics, Molecular and Clinical Pharmacology, Innsbruck Medical University, Innsbruck, Austria
    PLoS ONE 6:e20093. 2011
  5. doi request reprint Body adiposity index and other indexes of body composition in the SAPHIR study: association with cardiovascular risk factors
    Andreas Melmer
    Department of Internal Medicine I, Innsbruck Medical University, Innsbruck, Austria
    Obesity (Silver Spring) 21:775-81. 2013
  6. doi request reprint Comparison and evaluation of cardiac biomarkers in patients with intermittent claudication: results from the CAVASIC study
    Barbara Kollerits
    Division of Genetic Epidemiology, Department of Medical Genetics, Molecular and Clinical Pharmacology, Innsbruck Medical University, Innsbruck, Austria
    Clin Chem 59:692-702. 2013
  7. pmc Candidate gene sequencing of SLC11A2 and TMPRSS6 in a family with severe anaemia: common SNPs, rare haplotypes, no causative mutation
    Anita Kloss-Brandstätter
    Division of Genetic Epidemiology, Department of Medical Genetics, Molecular and Clinical Pharmacology, Innsbruck Medical University, Innsbruck, Austria
    PLoS ONE 7:e35015. 2012
  8. doi request reprint Evaluation of gene-obesity interaction effects on cholesterol levels: a genetic predisposition score on HDL-cholesterol is modified by obesity
    Claudia Lamina
    Division of Genetic Epidemiology, Department of Medical Genetics, Molecular and Clinical Pharmacology, Innsbruck Medical University, Schoepfstr 41, A 6020 Innsbruck, Austria
    Atherosclerosis 225:363-9. 2012
  9. pmc Sex and age interaction with genetic association of atherogenic uric acid concentrations
    Anita Brandstätter
    Division of Genetic Epidemiology, Department of Medical Genetics, Molecular and Clinical Pharmacology, Innsbruck Medical University, Schöpfstr 41, A 6020 Innsbruck, Austria
    Atherosclerosis 210:474-8. 2010
  10. pmc Lipoprotein (a) concentrations, apolipoprotein (a) phenotypes, and peripheral arterial disease in three independent cohorts
    Anja Laschkolnig
    Division of Genetic Epidemiology, Department of Medical Genetics, Molecular and Clinical Pharmacology, Innsbruck Medical University, Schöpfstr 41, A 6020 Innsbruck, Austria
    Cardiovasc Res 103:28-36. 2014

Collaborators

Detail Information

Publications18

  1. pmc Digging into the extremes: a useful approach for the analysis of rare variants with continuous traits?
    Claudia Lamina
    Division of Genetic Epidemiology, Department of Medical Genetics, Molecular, and Clinical Pharmacology, Innsbruck Medical University, Schopfstrasse 41, 6020 Innsbruck, Austria
    BMC Proc 5:S105. 2011
    ....
  2. doi request reprint Visualizing interaction effects: a proposal for presentation and interpretation
    Claudia Lamina
    Division of Genetic Epidemiology, Department of Medical Genetics, Molecular and Clinical Pharmacology, Innsbruck Medical University, Schöpfstr 41, A 6020 Innsbruck, Austria
    J Clin Epidemiol 65:855-62. 2012
    ..However, the interpretation of these models is often not clear. We propose several graphical presentations and corresponding statistical tests alleviating the interpretation of interaction effects...
  3. pmc Interaction of time-varying albumin and phosphorus on mortality in incident dialysis patients
    Emanuel Zitt
    Department of Nephrology and Dialysis, Academic Teaching Hospital, Feldkirch, Austria
    Clin J Am Soc Nephrol 6:2650-6. 2011
    ..We prospectively investigated the relationship and interaction between serum albumin and phosphorus with all-cause mortality in an inception cohort of incident dialysis patients...
  4. pmc Association of HbA1c values with mortality and cardiovascular events in diabetic dialysis patients. The INVOR study and review of the literature
    Gisela Sturm
    Division of Genetic Epidemiology, Department of Medical Genetics, Molecular and Clinical Pharmacology, Innsbruck Medical University, Innsbruck, Austria
    PLoS ONE 6:e20093. 2011
    ..Improved glycemic control reduces complications in patients with diabetes mellitus (DM). However, it is discussed controversially whether patients with diabetes mellitus and end-stage renal disease benefit from strict glycemic control...
  5. doi request reprint Body adiposity index and other indexes of body composition in the SAPHIR study: association with cardiovascular risk factors
    Andreas Melmer
    Department of Internal Medicine I, Innsbruck Medical University, Innsbruck, Austria
    Obesity (Silver Spring) 21:775-81. 2013
    ....
  6. doi request reprint Comparison and evaluation of cardiac biomarkers in patients with intermittent claudication: results from the CAVASIC study
    Barbara Kollerits
    Division of Genetic Epidemiology, Department of Medical Genetics, Molecular and Clinical Pharmacology, Innsbruck Medical University, Innsbruck, Austria
    Clin Chem 59:692-702. 2013
    ..However, there is limited information about the association and comparative performance of these peptides in peripheral arterial disease (PAD)...
  7. pmc Candidate gene sequencing of SLC11A2 and TMPRSS6 in a family with severe anaemia: common SNPs, rare haplotypes, no causative mutation
    Anita Kloss-Brandstätter
    Division of Genetic Epidemiology, Department of Medical Genetics, Molecular and Clinical Pharmacology, Innsbruck Medical University, Innsbruck, Austria
    PLoS ONE 7:e35015. 2012
    ..After excluding all known causes responsible for iron deficiency anaemia we searched for mutations in SLC11A2 and TMPRSS6 that could explain the severe anaemia in these children...
  8. doi request reprint Evaluation of gene-obesity interaction effects on cholesterol levels: a genetic predisposition score on HDL-cholesterol is modified by obesity
    Claudia Lamina
    Division of Genetic Epidemiology, Department of Medical Genetics, Molecular and Clinical Pharmacology, Innsbruck Medical University, Schoepfstr 41, A 6020 Innsbruck, Austria
    Atherosclerosis 225:363-9. 2012
    ..g. physical activity and diet) was observed in some candidate gene studies on lipids. We aimed to evaluate gene-obesity interaction effects on HDL (HDL-C), LDL (LDL-C) and total cholesterol (TC) levels using genetic predisposition scores...
  9. pmc Sex and age interaction with genetic association of atherogenic uric acid concentrations
    Anita Brandstätter
    Division of Genetic Epidemiology, Department of Medical Genetics, Molecular and Clinical Pharmacology, Innsbruck Medical University, Schöpfstr 41, A 6020 Innsbruck, Austria
    Atherosclerosis 210:474-8. 2010
    ..High serum uric acid levels are associated with gout, atherosclerosis and cardiovascular disease. Three genes (SLC2A9, ABCG2, and SLC17A3) were reported to be involved in the regulation of uric acid levels...
  10. pmc Lipoprotein (a) concentrations, apolipoprotein (a) phenotypes, and peripheral arterial disease in three independent cohorts
    Anja Laschkolnig
    Division of Genetic Epidemiology, Department of Medical Genetics, Molecular and Clinical Pharmacology, Innsbruck Medical University, Schöpfstr 41, A 6020 Innsbruck, Austria
    Cardiovasc Res 103:28-36. 2014
    ..Therefore, we analysed this association in three independent cohorts and performed a Mendelian Randomization approach using instrumental variable regression...
  11. doi request reprint Plasma concentrations of the vitamin E-binding protein afamin are associated with overall and progression-free survival and platinum sensitivity in serous ovarian cancer--a study by the OVCAD consortium
    Andreas Melmer
    Division of Genetic Epidemiology, Department of Medical Genetics, Molecular and Clinical Pharmacology, Innsbruck Medical University, Austria
    Gynecol Oncol 128:38-43. 2013
    ..This study evaluates the association of afamin with survival and response to therapy in serous OC patients within the OVCAD consortium project...
  12. doi request reprint Look beyond one's own nose: combination of information from publicly available sources reveals an association of GATA4 polymorphisms with plasma triglycerides
    Claudia Lamina
    Division of Genetic Epidemiology, Department of Medical Genetics, Molecular and Clinical Pharmacology, Innsbruck Medical University, Innsbruck, Austria
    Atherosclerosis 219:698-703. 2011
    ..Our approach is a more often applicable advance to uncover associations and their functional implications which would have been otherwise missed by standard genome-wide association studies (GWAS)...
  13. doi request reprint Sex-specific association of time-varying haemoglobin values with mortality in incident dialysis patients
    Gisela Sturm
    Division of Genetic Epidemiology, Department of Medical Genetics, Molecular and Clinical Pharmacology, Innsbruck Medical University, Schöpfstr 41, Innsbruck, Austria
    Nephrol Dial Transplant 25:2715-22. 2010
    ..Previous studies in dialysis patients showed an association between haemoglobin levels and all-cause mortality, however, without addressing sex differences...
  14. pmc Polymorphisms in the gene regions of the adaptor complex LAMTOR2/LAMTOR3 and their association with breast cancer risk
    Mariana E de Araujo
    Division of Cell Biology, Innsbruck Medical University, Innsbruck, Austria
    PLoS ONE 8:e53768. 2013
    ..Our aim was to address the possible role of genetic polymorphisms in LAMTOR2 and LAMTOR3 as genetic risk factors for breast cancer...
  15. pmc Investigation and functional characterization of rare genetic variants in the adipose triglyceride lipase in a large healthy working population
    Stefan Coassin
    Division of Genetic Epidemiology, Department of Medical Genetics, Molecular and Clinical Pharmacology, Innsbruck Medical University, Innsbruck, Austria
    PLoS Genet 6:e1001239. 2010
    ..In contrast to these rather small effects, we describe here also the first patient with "neutral lipid storage disease with myopathy" (NLSDM) with a point mutation in the catalytic dyad, but otherwise intact protein...
  16. doi request reprint Paradise lost or paradise regained? Changes in admission system affect academic performance and drop-out rates of medical students
    Hans Georg Kraft
    Department of Medical Genetics, Molecular and Clinical Pharmacology, Innsbruck Medical University, Innsbruck, Austria
    Med Teach 35:e1123-9. 2013
    ..Until this year admission to medical studies was unrestricted. Innsbruck Medical University chose the Eignungstest für das Medizinstudium in der Schweiz (EMS) aptitude test for admission testing...
  17. doi request reprint In vivo stable-isotope kinetic study suggests intracellular assembly of lipoprotein(a)
    Michael E Frischmann
    Division of Genetic Epidemiology, Department of Medical Genetics, Molecular and Clinical Pharmacology, Innsbruck Medical University, Austria
    Atherosclerosis 225:322-7. 2012
    ..To address the Lp(a) assembly mechanism, we studied the in vivo kinetics of apo(a) and apoB-100 from Lp(a) and LDL apoB-100 in nine healthy probands using stable-isotope methodology...
  18. pmc A common variant in the adiponutrin gene influences liver enzyme values
    Barbara Kollerits
    Division of Genetic Epidemiology, Department of Medical Genetics, Molecular and Clinical Pharmacology, Innsbruck Medical University, , A 6020 Innsbruck, Austria
    J Med Genet 47:116-9. 2010
    ..Conclusion The highly significant associations of this transversion polymorphism within the adiponutrin gene with increased ALT and AST concentrations support a role for adiponutrin as a susceptibility gene for hepatic dysfunction...