Dietmar Fries

Summary

Affiliation: Innsbruck Medical University
Country: Austria

Publications

  1. doi request reprint The early use of fibrinogen, prothrombin complex concentrate, and recombinant-activated factor VIIa in massive bleeding
    Dietmar Fries
    Department for General and Surgical Critical Care Medicine, Medical University Innsbruck, Innsbruck, Austria
    Transfusion 53:91S-95S. 2013
  2. doi request reprint [Coagulation Monitoring using ROTEM(®): Pro]
    Dietmar Fries
    Abteilung für Allgemeine und Chirurgische Intensivmedizin, der Medizinischen Universität Innsbruck, Germany
    Anasthesiol Intensivmed Notfallmed Schmerzther 46:312-6. 2011
  3. doi request reprint Thrombosis prophylaxis in critically ill patients
    Dietmar Fries
    Department of General and Surgical Intensive Care Medicine, Medical University of Innsbruck, Innsbruck, Austria
    Wien Med Wochenschr 161:68-72. 2011
  4. doi request reprint Role of fibrinogen in trauma-induced coagulopathy
    D Fries
    Department of General and Surgical Critical Care Medicine, Innsbruck Medical University, Anichstrasse 35, Innsbruck, Austria
    Br J Anaesth 105:116-21. 2010
  5. doi request reprint [Anticoagulation in critically ill patient]
    Dietmar Fries
    Klinische Abteilung für Allgemeine und Chirurgische Intensivmedizin, Universitätsklinik für Anästhesie und Allgemeine Intensivmedizin, Medizinische Universitat Innsbruck, Innsbruck, Austria
    Wien Med Wochenschr 159:487-91. 2009
  6. ncbi request reprint Hemostatic changes after crystalloid or colloid fluid administration during major orthopedic surgery: the role of fibrinogen administration
    Markus Mittermayr
    Department of Anesthesiology and Critical Care Medicine, Innsbruck Medical University, Innsbruck, Austria
    Anesth Analg 105:905-17, table of contents. 2007
  7. ncbi request reprint Coagulation changes and edema formation during long-distance bus travel
    Wolfgang Schobersberger
    University for Health Sciences, Medical Informatics and Technology Tyrol, Institute for Leisure, Travel and Alpine Medicine, Innsbruck, Austria
    Blood Coagul Fibrinolysis 15:419-25. 2004
  8. doi request reprint Detection of protamine and heparin after termination of cardiopulmonary bypass by thrombelastometry (ROTEM): results of a pilot study
    Markus Mittermayr
    Department of Anesthesiology and Critical Care Medicine, Innsbruck Medical University, Anichstr 35, A 6020 Innsbruck, Austria
    Anesth Analg 108:743-50. 2009
  9. doi request reprint The in vitro effects of fibrinogen concentrate, factor XIII and fresh frozen plasma on impaired clot formation after 60% dilution
    Thorsten Haas
    Department of Anaesthesiology and Critical Care Medicine, Innsbruck Medical University, Anichstrasse 35, 6020 Innsbruck, Austria
    Anesth Analg 106:1360-5, table of contents. 2008
  10. ncbi request reprint The effect of fibrinogen substitution on reversal of dilutional coagulopathy: an in vitro model
    Dietmar Fries
    Department of Anaesthesiology and Critical Care Medicine, Innsbruck Medical University, Innsbruck, Austria
    Anesth Analg 102:347-51. 2006

Detail Information

Publications30

  1. doi request reprint The early use of fibrinogen, prothrombin complex concentrate, and recombinant-activated factor VIIa in massive bleeding
    Dietmar Fries
    Department for General and Surgical Critical Care Medicine, Medical University Innsbruck, Innsbruck, Austria
    Transfusion 53:91S-95S. 2013
    ..The aim of any hemostatic therapy is to control bleeding and minimize blood loss and transfusion requirements. Transfusion of allogeneic blood products as well as the presence of coagulopathy cause increased morbidity and mortality...
  2. doi request reprint [Coagulation Monitoring using ROTEM(®): Pro]
    Dietmar Fries
    Abteilung für Allgemeine und Chirurgische Intensivmedizin, der Medizinischen Universität Innsbruck, Germany
    Anasthesiol Intensivmed Notfallmed Schmerzther 46:312-6. 2011
    ..New viscoelastic methods like the ROTEM® may help to improve coagulation monitoring and management even in the emergency situation or under critical care conditions...
  3. doi request reprint Thrombosis prophylaxis in critically ill patients
    Dietmar Fries
    Department of General and Surgical Intensive Care Medicine, Medical University of Innsbruck, Innsbruck, Austria
    Wien Med Wochenschr 161:68-72. 2011
    ..Severity of illness and SAPS II-score determine dosing of the direct thrombin inhibitor argatroban which needs to be about 10-times lower than in patients without critical illness...
  4. doi request reprint Role of fibrinogen in trauma-induced coagulopathy
    D Fries
    Department of General and Surgical Critical Care Medicine, Innsbruck Medical University, Anichstrasse 35, Innsbruck, Austria
    Br J Anaesth 105:116-21. 2010
    ..In multiple trauma patients, priority must be given to early and effective correction of impaired fibrin polymerization by administering fibrinogen concentrate...
  5. doi request reprint [Anticoagulation in critically ill patient]
    Dietmar Fries
    Klinische Abteilung für Allgemeine und Chirurgische Intensivmedizin, Universitätsklinik für Anästhesie und Allgemeine Intensivmedizin, Medizinische Universitat Innsbruck, Innsbruck, Austria
    Wien Med Wochenschr 159:487-91. 2009
    ..Dosing of the direct thrombin inhibitor argatroban depends on the severity of illness (SAPS II-score) and is up to 10-times lower than in patients without critical illness...
  6. ncbi request reprint Hemostatic changes after crystalloid or colloid fluid administration during major orthopedic surgery: the role of fibrinogen administration
    Markus Mittermayr
    Department of Anesthesiology and Critical Care Medicine, Innsbruck Medical University, Innsbruck, Austria
    Anesth Analg 105:905-17, table of contents. 2007
    ..To explore whether disturbed fibrin polymerization is the main problem underlying dilutional coagulopathy and can be reversed by fibrinogen administration, we conducted a prospective study using modified thrombelastography (ROTEM)...
  7. ncbi request reprint Coagulation changes and edema formation during long-distance bus travel
    Wolfgang Schobersberger
    University for Health Sciences, Medical Informatics and Technology Tyrol, Institute for Leisure, Travel and Alpine Medicine, Innsbruck, Austria
    Blood Coagul Fibrinolysis 15:419-25. 2004
    ..Thus, it is questionable whether hypoxia is the crucial risk factor for thromboembolic events after long-haul flights...
  8. doi request reprint Detection of protamine and heparin after termination of cardiopulmonary bypass by thrombelastometry (ROTEM): results of a pilot study
    Markus Mittermayr
    Department of Anesthesiology and Critical Care Medicine, Innsbruck Medical University, Anichstr 35, A 6020 Innsbruck, Austria
    Anesth Analg 108:743-50. 2009
    ..Our goal of this study was to determine whether protamine's effects on coagulation can be detected and differentiated from those of heparin when using thrombelastometry (ROTEM)...
  9. doi request reprint The in vitro effects of fibrinogen concentrate, factor XIII and fresh frozen plasma on impaired clot formation after 60% dilution
    Thorsten Haas
    Department of Anaesthesiology and Critical Care Medicine, Innsbruck Medical University, Anichstrasse 35, 6020 Innsbruck, Austria
    Anesth Analg 106:1360-5, table of contents. 2008
    ....
  10. ncbi request reprint The effect of fibrinogen substitution on reversal of dilutional coagulopathy: an in vitro model
    Dietmar Fries
    Department of Anaesthesiology and Critical Care Medicine, Innsbruck Medical University, Innsbruck, Austria
    Anesth Analg 102:347-51. 2006
    ..The effect of in vitro fibrinogen substitution on ROTEM variables was dependent on the fibrinogen dosage and the type of solution used to dilute the blood samples...
  11. ncbi request reprint Leg edema formation and venous blood flow velocity during a simulated long-haul flight
    Markus Mittermayr
    Department for General and Surgical Intensive Care Medicine, Medical University Innsbruck, Innsbruck, Austria
    Thromb Res 120:497-504. 2007
    ..At present no studies have been performed measuring the time course of lower limb blood flow, leg volume and leg tissue thickness during a long-haul flight...
  12. doi request reprint Time for changing coagulation management in trauma-related massive bleeding
    Dietmar Fries
    Department of General and Surgical Critical Care Medicine, Innsbruck Medical University, Austria
    Curr Opin Anaesthesiol 22:267-74. 2009
    ....
  13. doi request reprint Point-of-care whole blood impedance aggregometry versus classical light transmission aggregometry for detecting aspirin and clopidogrel: the results of a pilot study
    Corinna Velik-Salchner
    Department of Anesthesiology and Intensive Care Medicine, Innsbruck Medical University, Anichstrasse 35, A 6020 Innsbruck, Austria
    Anesth Analg 107:1798-806. 2008
    ..We determined whether whole blood impedance aggregometry using the Multiplate detects the effects of antiplatelet drugs as reliably as does classical light transmission aggregometry (LTA) or the platelet function analyzer PFA-100(R)...
  14. doi request reprint Fibrinogen in craniosynostosis surgery
    Thorsten Haas
    Department of Anaesthesiology and Critical Care Medicine, Innsbruck Medical University, Anichstrasse 35, 6020 Innsbruck, Austria
    Anesth Analg 106:725-31, table of contents. 2008
    ..We report our experience with human fibrinogen concentrate (Hemocomplettan) used to improve impaired fibrinogen polymerization in children...
  15. doi request reprint Microcirculatory parameters after isotonic and hypertonic colloidal fluid resuscitation in acute hemorrhagic shock
    Stephan Maier
    Department of Anesthesiology and Critical Care Medicine, Innsbruck Medical University, Innsbruck, Austria
    J Trauma 66:337-45. 2009
    ..We investigated sublingual mucosal microcirculatory parameters during hemorrhage and after fluid resuscitation with gelatin, hydroxyethyl starch, or hypertonic saline and hydroxyethyl starch in pigs...
  16. ncbi request reprint The effects of perioperatively administered crystalloids and colloids on concentrations of molecular markers of activated coagulation and fibrinolysis
    Dietmar Fries
    Department of Anaesthesia and Critical Care Medicine, The Leopold Franzens University of Innsbruck, Innsbruck, Austria
    Blood Coagul Fibrinolysis 15:213-9. 2004
    ..Thus, these results cannot confirm the hypothesis that crystalloid fluids per se cause hypercoagulability in vivo...
  17. doi request reprint Less impairment of hemostasis and reduced blood loss in pigs after resuscitation from hemorrhagic shock using the small-volume concept with hypertonic saline/hydroxyethyl starch as compared to administration of 4% gelatin or 6% hydroxyethyl starch solutio
    Thorsten Haas
    Department of Anaesthesiology and Critical Care Medicine, Innsbruck Medical University, Anichstrasse 35, 6020 Innsbruck, Austria
    Anesth Analg 106:1078-86, table of contents. 2008
    ..All i.v. fluids cause dose-related dilutional coagulopathy and show intrinsic effects on the hemostatic system, but only few data refer to functional consequences after small-volume resuscitation...
  18. doi request reprint The exclusive use of coagulation factor concentrates enables reversal of coagulopathy and decreases transfusion rates in patients with major blunt trauma
    Petra Innerhofer
    Clinic of Anaesthesiology and Intensive Care Medicine, Innsbruck Medical University, Innsbruck, Austria
    Injury 44:209-16. 2013
    ..FFP and coagulation factor concentrates are used to correct trauma-induced coagulopathy (TIC). However, data on coagulation profiles investigating effects of therapy are scarce...
  19. doi request reprint An assessment of cardiopulmonary bypass-induced changes in platelet function using whole blood and classical light transmission aggregometry: the results of a pilot study
    Corinna Velik-Salchner
    Department of Anesthesiology and Intensive Care Medicine, Innsbruck Medical University, Anichstrasse 35, A 6020 Innsbruck, Austria
    Anesth Analg 108:1747-54. 2009
    ..In this study, we explored whether antiplatelet medications impair whole blood impedance aggregometry after cardiac surgery and cardiopulmonary bypass (CPB) compared with classical light transmission aggregometry (LTA)...
  20. ncbi request reprint Coagulation monitoring and management of anticoagulation during cardiac assist device support
    Dietmar Fries
    Department of Anesthesia and Intensive Care Medicine, University of Innsbruck, Innsbruck, Austria
    Ann Thorac Surg 76:1593-7. 2003
    ..Moreover septic complications and insufficient anticoagulation are responsible for thromboembolic events...
  21. ncbi request reprint Successful reversal of deleterious coagulopathy by recombinant factor VIIa
    Thorsten Haas
    Department of Anesthesiology and Critical Care Medicine, Innsbruck Medical University, Anichstrasse 35, 6020 Innsbruck, Austria
    Anesth Analg 100:54-8. 2005
    ..Coagulation measurements improved, and transfusion requirements declined considerably. No adverse effects associated with rFVIIa were observed...
  22. ncbi request reprint Blood coagulation activation and fibrinolysis during a downhill marathon run
    Günther Sumann
    Division for General and Surgical Intensive Care Medicine, Clinic for Anesthesia and Intensive Care Medicine, Medical University of Innsbruck, Innsbruck, Austria
    Blood Coagul Fibrinolysis 18:435-40. 2007
    ..These changes were paralleled by an activation of fibrinolysis indicating a preserved hemostatic balance...
  23. ncbi request reprint Administration of recombinant activated factor VII (NovoSeven) in three cases of uncontrolled bleeding caused by disseminated intravascular coagulopathy
    Stefan Schmid
    Department of General and Surgical Critical Care Medicine, Innsbruck Medical University, Austria
    Clin Appl Thromb Hemost 13:313-7. 2007
    ..Recombinant factor VIIa might be an option for the treatment of severe bleeding complications in the case of DIC refractory to the conventional therapy...
  24. doi request reprint Fibrinogen concentrate in dilutional coagulopathy: a dose study in pigs
    Judith Martini
    Clinical Department of Anesthesiology and General Intensive Care Medicine, Medical University Innsbruck, Innsbruck, Austria Clinical Department of General and Surgical Intensive Care Medicine, Medical University Innsbruck, Innsbruck, Austria Department of Paediatrics, Medical University Innsbruck, Innsbruck, Austria US Army Institute of Surgical Research, Fort Sam Houston, Texas
    Transfusion 54:149-57. 2014
    ..Fibrinogen (150-600 mg/kg) normalized clot firmness and decreased blood loss. No signs of hypercoagulability or thromboembolism were detected after high dosages. ..
  25. doi request reprint [Coagulation management in trauma-related massive bleeding. - Recommendations of the Task Force for Coagulation (AGPG) of the Austrian Society of Anesthesiology, Resuscitation and Intensive Care Medicine (OGARI)]
    Dietmar Fries
    Klinische Abteilung für Allgemeine und Chirurgische Intensivmedizin, Medizinische Universitat Innsbruck, Osterreich
    Anasthesiol Intensivmed Notfallmed Schmerzther 45:552-61. 2010
    ....
  26. ncbi request reprint Normal values for thrombelastography (ROTEM) and selected coagulation parameters in porcine blood
    Corinna Velik-Salchner
    Department of Anaesthesia and Intensive Care Medicine, Innsbruck Medical University, Anichstrasse 35, A 6020 Innsbruck, Austria
    Thromb Res 117:597-602. 2006
    ..Normal values and reference intervals for porcine blood are given. As compared to the human reference intervals for the coagulation parameters investigated, porcine blood was found to be hypercoagulable...
  27. ncbi request reprint Formation of edema and fluid shifts during a long-haul flight
    Markus Mittermayr
    Clinic for Anesthesia and Intensive Care Medicine, The Leopold Franzens University of Innsbruck, Innsbruck, Austria
    J Travel Med 10:334-9. 2003
    ..The aim of our study was to evaluate edema formation in the leg and to investigate possible fluid shifts to the interstitial space under real flight conditions...
  28. ncbi request reprint Risk for postoperative infection after transfusion of white blood cell-filtered allogeneic or autologous blood components in orthopedic patients undergoing primary arthroplasty
    Petra Innerhofer
    Department of Anesthesia and Critical Care Medicine, University of Innsbruck, Innsbruck, Austria
    Transfusion 45:103-10. 2005
    ..This study was designed to obtain data on the incidence of postoperative infection in patients undergoing elective orthopedic surgery and receiving white blood cell (WBC)-filtered blood components prepared according to current standards...
  29. pmc Management of dabigatran-induced bleeding: expert statement
    Dietmar Fries
    Department of Anesthesia and Intensive Care, Medical University Innsbruck, Innsbruck, Austria
    Wien Klin Wochenschr 125:721-9. 2013
    ..It recommends an escalation of treatment measures as summarized in a pocket guide (see electronic supplementary material online and insert in the print issue). ..
  30. ncbi request reprint The effects of perioperatively administered colloids and crystalloids on primary platelet-mediated hemostasis and clot formation
    Petra Innerhofer
    Department of Anesthesia and Critical Care Medicine, Theoretical Surgery Unit, The Leopold Franzens University of Innsbruck, Innsbruck, Austria
    Anesth Analg 95:858-65, table of contents. 2002
    ..The reduction in total clot strength was due to impaired fibrinogen polymerization, resulting in a decreased fibrinogen part of the clot and reduced clot elasticity...