W Wolfgang Fleischhacker

Summary

Affiliation: Innsbruck Medical University
Country: Austria

Publications

  1. ncbi request reprint A double-blind, randomized comparative study of aripiprazole and olanzapine in patients with schizophrenia
    W Wolfgang Fleischhacker
    Department of Biological Psychiatry, Medical University of Innsbruck, Austria
    Biol Psychiatry 65:510-7. 2009
  2. pmc Schizophrenia--time to commit to policy change
    W Wolfgang Fleischhacker
    To whom correspondence should be addressed Innsbruck Medical University, Anichstrasse 35, A 6020 Innsbruck, Austria tel 43 512 504 23669, fax 43 512 504 25267, E mail
    Schizophr Bull 40:S165-94. 2014
  3. ncbi request reprint Completed and attempted suicides among 18,154 subjects with schizophrenia included in a large simple trial
    W Wolfgang Fleischhacker
    Department of Psychiatry and Psychotherapy, Medical University Innsbruck, Innsbruck, Austria 6020
    J Clin Psychiatry 75:e184-90. 2014
  4. doi request reprint Long-term safety and tolerability of aripiprazole once-monthly in maintenance treatment of patients with schizophrenia
    W Wolfgang Fleischhacker
    Department of Psychiatry and Psychotherapy, Division of Biological Psychiatry, Medical University Innsbruck, Innsbruck, Austria
    Int Clin Psychopharmacol 28:171-6. 2013
  5. doi request reprint Metabolic risk factors in first-episode schizophrenia: baseline prevalence and course analysed from the European First-Episode Schizophrenia Trial
    W Wolfgang Fleischhacker
    Department of Biological Psychiatry, Medical University Innsbruck, Innsbruck, Austria
    Int J Neuropsychopharmacol 16:987-95. 2013
  6. doi request reprint Interpreting treatment trials in schizophrenia patients: lessons learned from EUFEST
    W Wolfgang Fleischhacker
    Department of Psychiatry and Psychotherapy, Medical University Innsbruck, Innsbruck, Austria
    Schizophr Res 138:39-40. 2012
  7. ncbi request reprint Second-generation antipsychotic long-acting injections: systematic review
    W Wolfgang Fleischhacker
    Medical University Innsbruck, Department of Psychiatry and Psychotherapy, Anichstrasse 35, A 6020 Innsbruck, Austria
    Br J Psychiatry Suppl 52:S29-36. 2009
  8. ncbi request reprint Comorbid somatic illnesses in patients with severe mental disorders: clinical, policy, and research challenges
    W Wolfgang Fleischhacker
    Department of Biological Psychiatry, Medical University Innsbruck, Innsbruck, Austria
    J Clin Psychiatry 69:514-9. 2008
  9. ncbi request reprint Effects of adjunctive treatment with aripiprazole on body weight and clinical efficacy in schizophrenia patients treated with clozapine: a randomized, double-blind, placebo-controlled trial
    W Wolfgang Fleischhacker
    Biological Psychiatry Division, Medical University Innsbruck, Innsbruck, Austria
    Int J Neuropsychopharmacol 13:1115-25. 2010
  10. ncbi request reprint Brain activation patterns during a selective attention test--a functional MRI study in healthy volunteers and unmedicated patients during an acute episode of schizophrenia
    Elisabeth M Weiss
    Department of General Psychiatry, Medical University Innsbruck, Anichstrasse 35, A 6020 Innsbruck, Austria
    Psychiatry Res 154:31-40. 2007

Detail Information

Publications70

  1. ncbi request reprint A double-blind, randomized comparative study of aripiprazole and olanzapine in patients with schizophrenia
    W Wolfgang Fleischhacker
    Department of Biological Psychiatry, Medical University of Innsbruck, Austria
    Biol Psychiatry 65:510-7. 2009
    ..Few studies have directly compared the efficacy and tolerability of atypical agents...
  2. pmc Schizophrenia--time to commit to policy change
    W Wolfgang Fleischhacker
    To whom correspondence should be addressed Innsbruck Medical University, Anichstrasse 35, A 6020 Innsbruck, Austria tel 43 512 504 23669, fax 43 512 504 25267, E mail
    Schizophr Bull 40:S165-94. 2014
    ..Implementation of the above recommendations will require engagement by every stakeholder, but with commitment from all, change can be achieved. ..
  3. ncbi request reprint Completed and attempted suicides among 18,154 subjects with schizophrenia included in a large simple trial
    W Wolfgang Fleischhacker
    Department of Psychiatry and Psychotherapy, Medical University Innsbruck, Innsbruck, Austria 6020
    J Clin Psychiatry 75:e184-90. 2014
    ..To characterize subgroups of subjects with schizophrenia from the Ziprasidone Observational Study of Cardiac Outcomes (ZODIAC) trial who either completed or attempted suicide and those who did not...
  4. doi request reprint Long-term safety and tolerability of aripiprazole once-monthly in maintenance treatment of patients with schizophrenia
    W Wolfgang Fleischhacker
    Department of Psychiatry and Psychotherapy, Division of Biological Psychiatry, Medical University Innsbruck, Innsbruck, Austria
    Int Clin Psychopharmacol 28:171-6. 2013
    ..There were no unexpected changes in weight or shifts in fasting metabolic parameters across all study phases. ARI-OM had a safety and tolerability profile comparable with oral aripiprazole in maintenance treatment of schizophrenia...
  5. doi request reprint Metabolic risk factors in first-episode schizophrenia: baseline prevalence and course analysed from the European First-Episode Schizophrenia Trial
    W Wolfgang Fleischhacker
    Department of Biological Psychiatry, Medical University Innsbruck, Innsbruck, Austria
    Int J Neuropsychopharmacol 16:987-95. 2013
    ....
  6. doi request reprint Interpreting treatment trials in schizophrenia patients: lessons learned from EUFEST
    W Wolfgang Fleischhacker
    Department of Psychiatry and Psychotherapy, Medical University Innsbruck, Innsbruck, Austria
    Schizophr Res 138:39-40. 2012
    ..Implications for clinical trial design and the interpretation of such studies are discussed...
  7. ncbi request reprint Second-generation antipsychotic long-acting injections: systematic review
    W Wolfgang Fleischhacker
    Medical University Innsbruck, Department of Psychiatry and Psychotherapy, Anichstrasse 35, A 6020 Innsbruck, Austria
    Br J Psychiatry Suppl 52:S29-36. 2009
    ..Second-generation antipsychotics (SGAs) represent an advance in the long-term management of schizophrenia...
  8. ncbi request reprint Comorbid somatic illnesses in patients with severe mental disorders: clinical, policy, and research challenges
    W Wolfgang Fleischhacker
    Department of Biological Psychiatry, Medical University Innsbruck, Innsbruck, Austria
    J Clin Psychiatry 69:514-9. 2008
    ....
  9. ncbi request reprint Effects of adjunctive treatment with aripiprazole on body weight and clinical efficacy in schizophrenia patients treated with clozapine: a randomized, double-blind, placebo-controlled trial
    W Wolfgang Fleischhacker
    Biological Psychiatry Division, Medical University Innsbruck, Innsbruck, Austria
    Int J Neuropsychopharmacol 13:1115-25. 2010
    ..Improvements may reduce metabolic risk factors associated with clozapine treatment...
  10. ncbi request reprint Brain activation patterns during a selective attention test--a functional MRI study in healthy volunteers and unmedicated patients during an acute episode of schizophrenia
    Elisabeth M Weiss
    Department of General Psychiatry, Medical University Innsbruck, Anichstrasse 35, A 6020 Innsbruck, Austria
    Psychiatry Res 154:31-40. 2007
    ..Treatment with second generation antipsychotics may improve executive performance in patients with schizophrenia and facilitate a normalization of functional hypofrontality after symptomatic improvement...
  11. ncbi request reprint Patient outcomes in schizophrenia II: the impact of cognition
    Alex Hofer
    Department of Biological Psychiatry, Innsbruck Medical University, Anichstrasse 35, A 6020 Innsbruck, Austria
    Eur Psychiatry 20:395-402. 2005
    ..Associations have been found between the severity of cognitive deficits and social dysfunction, impairments in independent living, occupational limitations, and disturbances in quality of life (QOL)...
  12. ncbi request reprint Patient outcomes in schizophrenia I: correlates with sociodemographic variables, psychopathology, and side effects
    Alex Hofer
    Department of Biological Psychiatry, Innsbruck Medical University, Anichstrasse 35, A 6020 Innsbruck, Austria
    Eur Psychiatry 20:386-94. 2005
    ..The present cross-sectional study examined the relationships of psychopathology, side effects, and sociodemographic factors with treatment outcomes in terms of patients' quality of life (QOL), functioning, and needs for care...
  13. ncbi request reprint Early changes of plasma lipids during treatment with atypical antipsychotics
    Maria A Rettenbacher
    Department of Biological Psychiatry, Medical University Innsbruck, Innsbruck, Austria
    Int Clin Psychopharmacol 21:369-72. 2006
    ..These results are important with regard to the increased risk for cardiovascular complications in patients with schizophrenia...
  14. ncbi request reprint Correlates of subjective and functional outcomes in outpatient clinic attendees with schizophrenia and schizoaffective disorder
    Alex Hofer
    Department of Biological Psychiatry, Medical University Innsbruck, Anichstrasse 35, 6020 Innsbruck, Austria
    Eur Arch Psychiatry Clin Neurosci 256:246-55. 2006
    ..Our observations suggest that subjective and functional outcomes in highly compliant patients are mainly predicted by psychopathological symptoms and unchangeable sociodemographic variables...
  15. ncbi request reprint Alcohol and/or benzodiazepine use: different accidents--different impacts?
    Ilsemarie Kurzthaler
    Department of Biological Psychiatry, Medical University Innsbruck, Austria
    Hum Psychopharmacol 20:583-9. 2005
    ..This study adds evidence to the existing literature about the co-occurance of alcohol and/or benzodiazepine consumption and accident-related injuries...
  16. ncbi request reprint Alcohol and benzodiazepines in falls: an epidemiological view
    Ilsemarie Kurzthaler
    Department of Biological Psychiatry, Medical University Innsbruck, Anichstrasse 35, A 6020 Innsbruck, Austria
    Drug Alcohol Depend 79:225-30. 2005
    ..5%; females=2.4%). In addition, this study shows that alcohol plays a more important role in patients up to 70 years in fall-related accidents when compared to accidents of other causes...
  17. ncbi request reprint Quality of life in schizophrenia: the impact of psychopathology, attitude toward medication, and side effects
    Alex Hofer
    Department of Biological Psychiatry, Innsbruck University Clinics, Innsbruck, Austria
    J Clin Psychiatry 65:932-9. 2004
    ..Factors deemed relevant in this context include severity of symptoms, antipsychotic-induced side effects, sociodemographic variables, and patients' subjective response to medication...
  18. ncbi request reprint Neural correlates of episodic encoding and recognition of words in unmedicated patients during an acute episode of schizophrenia: a functional MRI study
    Alex Hofer
    Department of Biological Psychiatry, Innsbruck University Clinics, Austria
    Am J Psychiatry 160:1802-8. 2003
    ..The same procedure was used in this study to investigate unmedicated patients during an acute episode of schizophrenia...
  19. doi request reprint Factors influencing the choice of new generation antipsychotic medication in the treatment of patients with schizophrenia
    Monika Edlinger
    University Clinic of Biological Psychiatry, Department of Psychiatry and Psychotherapy, Medical University Innsbruck, Innsbruck, Austria
    Schizophr Res 113:246-51. 2009
    ..This prospective, naturalistic study investigated the factors influencing physicians' choice of antipsychotic drug therapy in the treatment of patients with schizophrenia...
  20. ncbi request reprint Executive function and memory in relation to olfactory deficits in alcohol-dependent patients
    Claudia I Rupp
    Department of Psychiatry, Innsbruck Medical University, Innsbruck, Austria
    Alcohol Clin Exp Res 30:1355-62. 2006
    ....
  21. ncbi request reprint Dropout rates in placebo-controlled and active-control clinical trials of antipsychotic drugs: a meta-analysis
    Georg Kemmler
    Department of General Psychiatry, Innsbruck University Clinics, Anichstrasse 35, A 6020 Innsbruck, Austria
    Arch Gen Psychiatry 62:1305-12. 2005
    ..Dropout rates in randomized clinical trials of antipsychotic drugs have consistently been reported to be high, and the use of a placebo-controlled design is hypothesized to be one of the reasons for this...
  22. ncbi request reprint Perceived functioning, well-being and psychiatric symptoms in patients with stable schizophrenia treated with long-acting risperidone for 1 year
    W Wolfgang Fleischhacker
    Department of Biological Psychiatry, Medical University Innsbruck, Anichstrasse 35, 6020 Innsbruck, Austria
    Br J Psychiatry 187:131-6. 2005
    ..The extent to which antipsychotics improve patients' well-being is uncertain...
  23. doi request reprint Sexual dysfunction in first-episode schizophrenia patients: results from European First Episode Schizophrenia Trial
    Peter Malik
    Department of Psychiatry and Psychotherapy, Medical University Innsbruck, Innsbruck, Austria
    J Clin Psychopharmacol 31:274-80. 2011
    ..In addition, there is a strong correlation between the prolactin-increasing properties of amisulpride and menstrual irregularities...
  24. ncbi request reprint Language lateralization in unmedicated patients during an acute episode of schizophrenia: a functional MRI study
    Elisabeth M Weiss
    Department of General Psychiatry, Anichstrasse 35, Innsbruck Medical University, A 6020 Innsbruck, Austria
    Psychiatry Res 146:185-90. 2006
    ..These results suggest that decreased language lateralization is also evident in unmedicated patients experiencing an acute episode of schizophrenia...
  25. ncbi request reprint Cognitive impairment in schizophrenia: clinical ratings are not a suitable alternative to neuropsychological testing
    Alex Hofer
    Medical University Innsbruck, Department of Biological Psychiatry, Anichstrasse 35, A 6020 Innsbruck, Austria
    Schizophr Res 92:126-31. 2007
    ..These data clearly show that clinical assessment of cognitive deficits by the PANSS is not a viable alternative to neuropsychological testing to obtain information about cognitive functioning in schizophrenia...
  26. doi request reprint Attitudes of patients with schizophrenia and depression towards psychiatric research
    Monika Edlinger
    Medical University Innsbruck, Department of Psychiatry and Psychotherapy, University Clinic of Biological Psychiatry, Anichstrasse 35, A 6020 Innsbruck, Austria
    Psychiatry Res 177:172-6. 2010
    ..Our findings confirm and extend those of other groups. This should encourage psychiatrists at least in academic settings where most of this research has been done to approach patients to take part in clinical research...
  27. doi request reprint Low bone mineral density and impaired bone metabolism in young alcoholic patients without liver cirrhosis: a cross-sectional study
    Peter Malik
    Department of Biological Psychiatry, Medical University Innsbruck, Anichstrasse 35, Innsbruck, Austria
    Alcohol Clin Exp Res 33:375-81. 2009
    ..Ethanol's direct effect on bone-modeling cells as well as alcoholism-related "life-style factors" such as malnutrition, lack of exercise, hormonal changes, and liver cirrhosis are discussed as potential causative factors...
  28. ncbi request reprint Neural substrates for episodic encoding and recognition of unfamiliar faces
    Alex Hofer
    Medical University Innsbruck, Department of Biological Psychiatry, Anichstrasse 35, A 6020 Innsbruck, Austria
    Brain Cogn 63:174-81. 2007
    ..These results support the view that the successful episodic retrieval of newly learned faces is based on a dorsal visual stream mechanism...
  29. ncbi request reprint Schizophrenia: attitudes of patients and professional carers towards the illness and antipsychotic medication
    Maria A Rettenbacher
    Department of Biological Psychiatry, Innsbruck University Clinics, Innsbruck, Austria
    Pharmacopsychiatry 37:103-9. 2004
    ....
  30. ncbi request reprint Osteoporosis in patients with schizophrenia
    Martina Hummer
    Department of Biological Psychiatry, Innsbruck University Hospital, Austria
    Am J Psychiatry 162:162-7. 2005
    ..The authors' goals were to investigate the association between schizophrenia and a decrease in bone mineral density and to get more insight into potential underlying pathophysiological mechanisms...
  31. ncbi request reprint Association between antipsychotic-induced elevation of liver enzymes and weight gain: a prospective study
    Maria A Rettenbacher
    Department of Biological Psychiatry, Medical University Innsbruck, Anichstrasse, Innsbruck, Austria
    J Clin Psychopharmacol 26:500-3. 2006
    ..We conclude that antipsychotic-induced elevation of liver enzymes is mostly transient and could be associated with weight gain...
  32. ncbi request reprint QTc variability in schizophrenia patients treated with antipsychotics and healthy controls
    Maria A Rettenbacher
    Department of Biological Psychiatry, Innsbruck University Hospital, A 6020 Innsbruck, Austria
    J Clin Psychopharmacol 25:206-10. 2005
    ....
  33. ncbi request reprint Olanzapine induces insulin resistance: results from a prospective study
    Christoph F Ebenbichler
    Department of Medicine, University of Innsbruck, Innsbruck, Austria
    J Clin Psychiatry 64:1436-9. 2003
    ..The aim of this study was to compare glucose metabolism in patients with schizophrenia receiving olanzapine with that in control subjects...
  34. ncbi request reprint Cognitive remediation therapy during treatment for alcohol dependence
    Claudia I Rupp
    Division of Biological Psychiatry, Department of Psychiatry and Psychotherapy, Innsbruck Medical University, Innsbruck, Austria
    J Stud Alcohol Drugs 73:625-34. 2012
    ..A secondary aim was to evaluate whether the benefits of CR generalize to noncognitive clinically meaningful outcomes at the end of inpatient treatment...
  35. ncbi request reprint Trends in the pharmacological treatment of patients with schizophrenia over a 12 year observation period
    Monika Edlinger
    Department of Biological Psychiatry, Medical University Innsbruck Anichstrasse 35 A 6020, Austria
    Schizophr Res 77:25-34. 2005
    ..All in all, the pharmacological management of schizophrenia patients is increasingly in tune with current treatment guidelines...
  36. ncbi request reprint The safety of clozapine in the treatment of first- and multiple-episode patients with treatment-resistant schizophrenia
    Alex Hofer
    Department of Biological Psychiatry, Innsbruck University Clinics, Innsbruck, Austria
    Int J Neuropsychopharmacol 6:201-6. 2003
    ..With regard to side-effects, we could not find any significant difference between groups. Altogether, response and side-effects to clozapine treatment do not seem to be determined by the chronicity of the disorder...
  37. ncbi request reprint Placebo or active control trials of antipsychotic drugs?
    W Wolfgang Fleischhacker
    Department of Biological Psychiatry, Innsbruck University Clinics, Austria
    Arch Gen Psychiatry 60:458-64. 2003
    ..Sample size requirements for various equivalence margins in noninferiority trials are provided. Scientific and ethical arguments should lead to a more frequent use of the active-control noninferiority trial design...
  38. ncbi request reprint Brain activation patterns during a selective attention test-a functional MRI study in healthy volunteers and patients with schizophrenia
    Elisabeth M Weiss
    Department of Biological Psychiatry, Innsbruck University Clinics, Anichstrasse 35, A 6020 Innsbruck, Austria
    Psychiatry Res 123:1-15. 2003
    ....
  39. ncbi request reprint Gender differences in regional cerebral activity during the perception of emotion: a functional MRI study
    Alex Hofer
    Medical University Innsbruck, Department of Biological Psychiatry, Anichstrasse 35, A 6020 Innsbruck, Austria
    Neuroimage 32:854-62. 2006
    ..Our findings suggest gender-related neural responses to emotional stimuli and could contribute to the understanding of mechanisms underlying gender-related vulnerability of the prevalence and severity of neuropsychiatric disorders...
  40. ncbi request reprint Various bilateral olfactory deficits in male patients with schizophrenia
    Claudia I Rupp
    Department of General Psychiatry, Innsbruck Medical University, Anichstrasse 35, 6020 Innsbruck, Austria
    Schizophr Bull 31:155-65. 2005
    ..Olfactory dysfunctions were found across both nostrils. Results suggest specific dysfunctions in olfactory processing in schizophrenia patients, including early stages of the odor identification process...
  41. ncbi request reprint Olfactory functions and volumetric measures of orbitofrontal and limbic regions in schizophrenia
    Claudia I Rupp
    Department of Psychiatry, Medical University Innsbruck, Austria
    Schizophr Res 74:149-61. 2005
    ..In this study, we examined the relationship between different olfactory functions and volumes of the hippocampus-amygdala complex (HAC) and the orbitofrontal brain region using magnetic resonance imaging (MRI)...
  42. ncbi request reprint Brain activation patterns during a verbal fluency test-a functional MRI study in healthy volunteers and patients with schizophrenia
    Elisabeth M Weiss
    Department of Biological Psychiatry, Innsbruck University Clinics, Anichstrasse 35, 6020 Innsbruck, Austria
    Schizophr Res 70:287-91. 2004
    ..These data indicate that high-functioning schizophrenia patients show a reduced language lateralization of the frontal cortex compared to healthy controls...
  43. ncbi request reprint Treatment of schizophrenia with long-acting injectable risperidone: a 12-month open-label trial of the first long-acting second-generation antipsychotic
    W Wolfgang Fleischhacker
    Department of Biological Psychiatry, Innsbruck University Clinics, Anichstrasse 35, 6020 Innsbruck, Austria
    J Clin Psychiatry 64:1250-7. 2003
    ..The long-term safety and efficacy of long-acting injectable risperidone, the first long-acting second-generation antipsychotic, were evaluated in stable patients with schizophrenia...
  44. ncbi request reprint The European First Episode Schizophrenia Trial (EUFEST): rationale and design of the trial
    W Wolfgang Fleischhacker
    Department of Biological Psychiatry, Medical University Innsbruck, Anichstrasse 35, A 6020 Innsbruck, Austria
    Schizophr Res 78:147-56. 2005
    ..These and other facts have stimulated discussions regarding the effectiveness of the new generation of antipsychotics...
  45. ncbi request reprint Second-generation antipsychotics: are their similarities greater than their differences?
    W Wolfgang Fleischhacker
    Department of Biological Psychiatry, Innsbruck University Clinics, Innsbruck, Austria
    Eur Psychiatry 18:38s-45s. 2003
    ..Therefore, clinicians must make an individualised treatment decision, and select the most appropriate antipsychotic agent for each patient...
  46. ncbi request reprint Experimental antipsychotics and metabolic adverse effects--findings from clinical trials
    Alexander Tschoner
    Department of Internal Medicine I, Medical University Innsbruck, Center of Internal Medicine, 6020 Innsbruck, Austria
    Curr Opin Investig Drugs 10:1041-8. 2009
    ..This review discusses some of the most recently developed antipsychotic compounds that have undergone clinical assessment from the perspective of their metabolic impact...
  47. ncbi request reprint Aripiprazole
    W Wolfgang Fleischhacker
    Department of Biological Psychiatry, Medical University Innsbruck, Austria
    Expert Opin Pharmacother 6:2091-101. 2005
    ..Further studies in other indications and clinical trials that confirm results from the Phase II and III clinical development programme are eagerly awaited...
  48. doi request reprint Facial affect recognition in symptomatically remitted patients with schizophrenia and bipolar disorder
    Nursen Yalcin-Siedentopf
    Medical University Innsbruck, Department of Psychiatry and Psychotherapy, Biological Psychiatry Division, Anichstrasse 35, A 6020 Innsbruck, Austria Electronic address
    Schizophr Res 152:440-5. 2014
    ..However, in the psychosocial context BD patients seem to be more sensitive to residual symptomatology...
  49. ncbi request reprint Sibutramine in the treatment of antipsychotic-induced weight gain: a pilot study in patients with schizophrenia
    Falko Biedermann
    aDepartment of Psychiatry and Psychotherapy, Biological Psychiatry Division bDepartment of Internal Medicine I, Medical University Innsbruck, Innsbruck cDepartment of Internal and Geriatric Medicine, Hochzirl Hospital, Zirl, Austria
    Int Clin Psychopharmacol 29:181-4. 2014
    ..This pilot trial suggests that adjunctive treatment with sibutramine may be safe and effective in schizophrenic patients with antipsychotic-induced weight gain...
  50. ncbi request reprint Olanzapine-induced weight gain and disturbances of lipid and glucose metabolism
    Ursula eder-Ischia
    Department of Biological Psychiatry, Innsbruck University Clinics, Innsbruck, Austria
    Essent Psychopharmacol 6:112-7. 2005
    ..Clinicians should take these risks seriously in prescribing these antipsychotics and employ intelligent safeguards if and when they use them...
  51. ncbi request reprint An FMRI study of episodic encoding and recognition of words in patients with schizophrenia in remission
    Alex Hofer
    Department of Biological Psychiatry and Radiology, Innsbruck University Clinics, Anichstrasse 35, A 6020 Innsbruck, Austria
    Am J Psychiatry 160:911-8. 2003
    ..Verbal memory deficits are among the most severe cognitive deficits observed in patients with schizophrenia. This study examined patterns of brain activity during episodic encoding and recognition of words in patients with schizophrenia...
  52. ncbi request reprint Attitudes of patients with schizophrenia toward placebo-controlled clinical trials
    Martina Hummer
    Department of Biological Psychiatry, Innsbruck University Clinics, Innsbruck, Austria
    J Clin Psychiatry 64:277-81. 2003
    ..Although much is known about the opinions of professionals concerning this issue, so far nothing is known about the opinions of patients who are most affected by the realization of placebo-controlled clinical trials...
  53. ncbi request reprint Normative data for functional assessment of cancer therapy--general scale and its use for the interpretation of quality of life scores in cancer survivors
    Bernhard Holzner
    Department of Biological Psychiatry, Innsbruck University Hospital, Innsbruck, Austria
    Acta Oncol 43:153-60. 2004
    ..Furthermore, unless patient data are compared with normative values, phenomena such as adaptation and response shift might be missed or misinterpreted...
  54. ncbi request reprint The effect of nabilone on neuropsychological functions related to driving ability: an extended case series
    Ilsemarie Kurzthaler
    Department of Biological Psychiatry, Innsbruck University Clinics, Austria
    Hum Psychopharmacol 20:291-3. 2005
    ..No indication was found of a deterioration of any of the five investigated neuropsychological functions during the 4-week treatment period with nabilone...
  55. doi request reprint Long-acting injectable formulations of new-generation antipsychotics: a review from a clinical perspective
    Anna Sophia Rauch
    Department of Psychiatry and Psychotherapy, Biological Psychiatry Division, Medical University Innsbruck, Anichstr 35, 6020, Innsbruck, Austria
    CNS Drugs 27:637-52. 2013
    ..The purpose of this manuscript is to review the recent clinical evidence on new-generation depot antipsychotics. ..
  56. ncbi request reprint Combined clozapine and electroconvulsive therapy in clozapine-resistant schizophrenia: clinical and cognitive outcomes
    Falko Biedermann
    From the Departments of Biological Psychiatry, and General Psychiatry, Medical University of Innsbruck, Innsbruck, Austria
    J ECT 27:e61-2. 2011
    ..The Positive and Negative Syndrome Scale total score decreased, and all cognitive measures improved.Electroconvulsive therapy would seem to be a safe treatment option for treatment-refractory schizophrenia patients...
  57. doi request reprint Emerging drugs for schizophrenia
    Falko Biedermann
    Medical University Innsbruck, Department for Psychiatry and Psychotherapy, Clinic for Biological Psychiatry, Anichstrasse 35, A 6020 Innsbruck Austria
    Expert Opin Emerg Drugs 16:271-82. 2011
    ..Managing psychotic symptoms is only one facet of successful treatment of schizophrenia. Effective remedies against negative symptoms and cognitive deficits are still an unmet clinical need...
  58. ncbi request reprint Factors influencing compliance in schizophrenia patients
    W Wolfgang Fleischhacker
    Department of Biological Psychiatry, Innsbruck University Clinics, Innsbruck, Austria
    J Clin Psychiatry 64:10-3. 2003
    ....
  59. ncbi request reprint Switching between second-generation antipsychotics: why and how?
    Monika Edlinger
    Department of Biological Psychiatry, Innsbruck Medical University, Innsbruck, A 6020, Austria
    CNS Drugs 19:27-42. 2005
    ..We review the available evidence concerning techniques, problems and consequences when switching from one second-generation antipsychotic agent to another and discuss potential difficulties...
  60. ncbi request reprint Treatment of schizophrenia patients: comparing new-generation antipsychotics to each other
    W Wolfgang Fleischhacker
    Department of Biological Psychiatry, Medical University Innsbruck, Innsbruck, Austria
    Curr Opin Psychiatry 19:128-34. 2006
    ....
  61. ncbi request reprint Olfactory functioning in patients with alcohol dependence: impairments in odor judgements
    Claudia I Rupp
    Medical University Innsbruck, Department of Psychiatry, Anichstrasse 35, 6020 Innsbruck, Austria
    Alcohol Alcohol 39:514-9. 2004
    ..However, olfactory functioning with regard to the immediate, perception driven odor associations is unknown. Therefore, this study assessed olfactory judgements in nonamnesic and nondemented patients with alcohol dependence...
  62. doi request reprint Poor health behaviour and reduced quality of life of people treated with psychotropic drugs
    Martin Kopp
    Department of Sport Science, University of Innsbruck, Innsbruck, Austria
    Hum Psychopharmacol 26:161-7. 2011
    ..We have investigated health behaviour, quality of life, and sociodemographic variables of people with psychopharmacological treatment using data from the most recent Austrian Health Survey...
  63. doi request reprint Antipsychotics in the early stage of development
    Falko Biedermann
    Department of Biological Psychiatry, Medical University Innsbruck, Innsbruck, Tyrol, Austria
    Curr Opin Psychiatry 22:326-30. 2009
    ....
  64. ncbi request reprint Alcohol and/or benzodiazepine use in injured road users
    Ilsemarie Kurzthaler
    Innsbruck University Clinics, Department of Biological Psychiatry, Innsbruck, Austria
    Hum Psychopharmacol 18:361-7. 2003
    ..Concerning alcohol or benzodiazepine use, females showed lower frequencies of both alcohol and benzodiazepine positive blood samples. The frequency of alcohol use was higher in patients <or= 60 years of age...
  65. ncbi request reprint Clock drawing, clock reading, clock setting, and judgment of clock faces in elderly people with dementia and depression
    Thomas Bodner
    Department of Biological Psychiatry, Innsbruck University Clinics, Innsbruck, Austria
    J Am Geriatr Soc 52:1146-50. 2004
    ..To assess patient performance on different clock tasks...
  66. doi request reprint Tolerability of antipsychotics: recent controversies and future management
    W Wolfgang Fleischhacker
    Department of Biological Psychiatry, Medical University of Innsbruck, Austria
    J Clin Psychiatry 70:e06. 2009
    ....
  67. ncbi request reprint No evidence for an association between serum cholesterol and the course of depression and suicidality
    Eberhard A Deisenhammer
    Department of General Psychiatry, Innsbruck University Hospital, Anichstrasse 35, A 6020, Innsbruck, Austria
    Psychiatry Res 121:253-61. 2004
    ..Cholesterol levels do not appear to be an appropriate biological marker for suicidality during the first 4 weeks of treatment in patients with a major depressive episode...
  68. ncbi request reprint The effects of second-generation antipsychotics on cognitive functioning and psychosocial outcome in schizophrenia
    Elisabeth M Weiss
    Department of Biological Psychiatry, Innsbruck University Clinics, Anichstrasse 35, 6020 Innsbruck University Clinics, Anichtrasse 35, 6020 Innsbruck, Austria
    Psychopharmacology (Berl) 162:11-7. 2002
    ..In this context it also addresses several methodological and conceptional issues that limited the comparison of these studies...
  69. ncbi request reprint Feasibility of placebo-controlled clinical trials of antipsychotic compounds in Europe
    W Wolfgang Fleischhacker
    Department of Biological Psychiatry, Innsbruck University Clinics, Anichstrasse 35, 6020 Innsbruck, Austria
    Psychopharmacology (Berl) 162:82-4. 2002
    ..Most recent phase II and phase III PCTs of antipsychotics in schizophrenia have been conducted outside Europe. This development needs to be better understood...
  70. ncbi request reprint Reduced olfactory sensitivity, discrimination, and identification in patients with alcohol dependence
    Claudia I Rupp
    University Clinics of Innsbruck, Department of General Psychiatry, Anichstrasse 35, 6020 Innsbruck, Austria
    Alcohol Clin Exp Res 27:432-9. 2003
    ..Various olfactory deficits have been reported in the alcohol-induced amnestic syndrome (Korsakoff's syndrome). Less is known about olfactory functioning in nonamnesic and nondemented alcoholic patients...