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Genomes and Genes | G DaumSummaryAffiliation: Graz University of Technology Country: Austria Publications
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Publications
Systematic analysis of yeast strains with possible defects in lipid metabolismG Daum
Institut fur Biochemie und Lebensmittelchemie, Technische Universitat, Graz, Austria
Yeast 15:601-14. 1999..Finally, lipid composition of mutant strains deleted of the respective open reading frames was determined. For some genes we found evidence suggesting a possible role in lipid metabolism...- Biochemistry, cell biology and molecular biology of lipids of Saccharomyces cerevisiaeG Daum
Institut fur Biochemie und Lebensmittelchemie, Technische Universitat, Petersgasse, Graz, Austria
Yeast 14:1471-510. 1998..Finally, we discuss distinct functions of certain key lipids and their possible roles in cellular processes... 
Electrospray ionization tandem mass spectrometry (ESI-MS/MS) analysis of the lipid molecular species composition of yeast subcellular membranes reveals acyl chain-based sorting/remodeling of distinct molecular species en route to the plasma membraneR Schneiter
Spezialforschungsbereich Biomembrane Research Center, Institut fur Biochemie und Lebensmittelchemie, Technische Universitat Graz, A 8010 Graz, Austria
J Cell Biol 146:741-54. 1999..This observation suggests that acyl chain-based sorting and/or remodeling mechanisms are operating to maintain the specific lipid molecular species composition of the yeast plasma membrane...- 1-Acyldihydroxyacetone-phosphate reductase (Ayr1p) of the yeast Saccharomyces cerevisiae encoded by the open reading frame YIL124w is a major component of lipid particlesK Athenstaedt
Institut fur Biochemie und Lebensmittelchemie, Technische Universitat, Spezialforschungsbereich Biomembrane Research Center, Petersgasse 12 2, A 8010 Graz, Austria
J Biol Chem 275:235-40. 2000..Taken together, these results identified Ayr1p of the yeast as the first ADR from any organism at the molecular level... - Phospholipid synthesis and lipid composition of subcellular membranes in the unicellular eukaryote Saccharomyces cerevisiaeE Zinser
Institut fur Biochemie und Lebensmittelchemie, Technische Universitat Graz, Austria
J Bacteriol 173:2026-34. 1991..The rigidity of the plasma membrane and of secretory vesicles, determined by measuring fluorescence anisotropy by using trimethylammonium diphenylhexatriene as a probe, can be attributed to the high content of ergosterol... - Biosynthesis of phosphatidic acid in lipid particles and endoplasmic reticulum of Saccharomyces cerevisiaeK Athenstaedt
SFB Biomembrane Research Center, Institut fur Biochemie und Lebensmittelchemie, Technische Universitat, Graz, Austria
J Bacteriol 179:7611-6. 1997..Thus, yeast contains at least two independent systems of phosphatidic acid biosynthesis... - A subfraction of the yeast endoplasmic reticulum associates with the plasma membrane and has a high capacity to synthesize lipidsH Pichler
, , and SFB Biomembrane Research Center, Graz, Austria
Eur J Biochem 268:2351-61. 2001..A possible role of PAM in the supply of lipids to the plasma membrane is discussed... - Contribution of Are1p and Are2p to steryl ester synthesis in the yeast Saccharomyces cerevisiaeD Zweytick
Institut fur Biochemie und Lebensmittelchemie, Technische Universität Graz and SFB Biomembrane Research Center, Graz, Austria
Eur J Biochem 267:1075-82. 2000.... - Identification and characterization of major lipid particle proteins of the yeast Saccharomyces cerevisiaeK Athenstaedt
Institut fur Biochemie und Lebensmittelchemie, Technische Universität and SFB Biomembrane Research Center, Petersgasse 12 2, A 8010 Graz, Austria
J Bacteriol 181:6441-8. 1999..Strains with YBR177c, YMR313c, and YKL140w deleted exhibited phospholipid and/or neutral lipid patterns that were different from the wild-type strain and thus may be further candidate ORFs involved in yeast lipid metabolism... - Biochemical characterization and subcellular localization of the sterol C-24(28) reductase, erg4p, from the yeast saccharomyces cerevisiaeD Zweytick
Institut fur Biochemie und Lebensmittelchemie, Technische Universität and SFB Biomembrane Research Center, Petersgasse 12 2, A 8010, Graz, Austria
FEBS Lett 470:83-7. 2000..We conclude that ergosterol biosynthesis is completed in the endoplasmic reticulum, and the final product is supplied from there to its membranous destinations... - YDL142c encodes cardiolipin synthase (Cls1p) and is non-essential for aerobic growth of Saccharomyces cerevisiaeG Tuller
Institut fur Biochemie und Lebensmittelchemie, Technische Universitat Graz, Austria
FEBS Lett 421:15-8. 1998..Collectively, these data indicate that cardiolipin is not essential for aerobic growth of Saccharomyces cerevisiae... - Phospholipid-synthesizing enzymes in Golgi membranes of the yeast, Saccharomyces cerevisiaeA Leber
Institut fur Biochemie und Lebensmittelchemie, Technische Universitat Graz, Austria
FEBS Lett 377:271-4. 1995..Two phospholipid-synthesizing enzymes, namely phosphatidylinositol synthase and sn-1,2-diacylglycerol cholinephosphotransferase, are detected in the Golgi at a specific activity which exceeds that of the endoplasmic reticulum... - Deletion of six open reading frames from the left arm of chromosome IV of Saccharomyces cerevisiaeG Tuller
SFB Biomembrane Research Center and Institut für Biochemie und Lebensmittelchemie, Technische Universitat Graz, Austria
Yeast 15:1275-85. 1999..The other deletion mutants grew like wild-type at different temperatures and on different carbon sources. A brief computational analysis of the six ORFs studied in this work is presented... - PDR16 and PDR17, two homologous genes of Saccharomyces cerevisiae, affect lipid biosynthesis and resistance to multiple drugsH B van den Hazel
Unite de Biochimie Physiologique, Universite Catholique de Louvain, Belgium
J Biol Chem 274:1934-41. 1999..Collectively, our results indicate that PDR16 and PDR17 control levels of various lipids in various compartments of the cell and thereby provide a mechanism for multidrug resistance unrecognized so far... - Mrs5p, an essential protein of the mitochondrial intermembrane space, affects protein import into yeast mitochondriaE Jarosch
Institut fur Mikrobiologie und Genetik, Universitat Wien, A 1030 Vienna, Austria
J Biol Chem 271:17219-25. 1996..Depletion of Mrs5p in yeast cells causes accumulation of unprocessed precursors of the mitochondrial hsp60 protein and defects in all cytochrome complexes. These findings suggest an essential role of Mrs5p in mitochondrial biogenesis... - Formation and mobilization of neutral lipids in the yeast Saccharomyces cerevisiaeA Wagner
Institute of Biochemistry, Graz University of Technology, Petersgasse 12 2, A 8010 Graz, Austria
Biochem Soc Trans 33:1174-7. 2005..The role of these proteins in biosynthesis and mobilization of TAG and STE, and the regulation of these processes will be discussed in this minireview... - In yeast sterol biosynthesis the 3-keto reductase protein (Erg27p) is required for oxidosqualene cyclase (Erg7p) activityC Mo
Biology Department, Indiana University Purdue University Indianapolis, 723 West Michigan Street, Indianapolis, IN 46202, USA
Biochim Biophys Acta 1633:68-74. 2003..We suggest that the physical interaction of Erg27p with Erg7p is an essential regulatory tool in yeast sterol biosynthesis... - Triacylglycerol biosynthesis in yeastD Sorger
, , Petersgasse 12/2, Austria
Appl Microbiol Biotechnol 61:289-99. 2003..The interplay of these organelles, formation of LP, and enzymatic properties of enzymes catalyzing the synthesis of PA, DAG, and TAG in yeast are discussed in this communication... - Dual localization of squalene epoxidase, Erg1p, in yeast reflects a relationship between the endoplasmic reticulum and lipid particlesR Leber
Institut für Biochemie und Lebensmittelchemie and SFB Biomembrane Research Center, Technische Universitat Graz, 1121 Vienna, Austria
Mol Biol Cell 9:375-86. 1998..Close contact between lipid particles and endoplasmic reticulum may be necessary for a concerted action of these two compartments in sterol biosynthesis... - Roles of phosphatidylethanolamine and of its several biosynthetic pathways in Saccharomyces cerevisiaeR Birner
, , Austria
Mol Biol Cell 12:997-1007. 2001..Thus, PtdEtn depletion does not affect protein secretion in general, suggesting that high levels of nonbilayer-forming lipids such as PtdEtn are not essential for membrane vesicle fusion processes in vivo... - Subcellular and submitochondrial localization of phospholipid-synthesizing enzymes in Saccharomyces cerevisiaeK Kuchler
J Bacteriol 165:901-10. 1986..Data concerning susceptibility to various inhibitors, heat sensitivity, and the pH optima indicate that there is a close similarity of the mitochondrial and microsomal enzymes that catalyze the same reaction... - Import of proteins into mitochondria. Cytochrome b2 and cytochrome c peroxidase are located in the intermembrane space of yeast mitochondriaG Daum
J Biol Chem 257:13028-33. 1982..The availability of submitochondrial fractions provides a basis for studying import of precursor polypeptides into isolated yeast mitochondria... - Dynamics of neutral lipid storage and mobilization in yeastG Daum
Institute of Biochemistry, Graz University of Technology, Petersgasse 12 2, 8010 Graz, Austria
Biochimie 89:243-8. 2007..The fact that neutral lipid homeostasis is linked to a number of cell biological processes confirms the important role of this class of lipids as cellular modulators or effectors...