Affiliation: Elisabethinen Hospital
- The clinical impact of DNA methylation frequencies of JAK2 negative regulators in patients with essential thrombocythemiaMathilde Födermayr
Department of Internal Medicine I, Elisabethinen Hospital, Linz, Austria
Leuk Res 36:588-90. 2012..Taken together, regarding the genomic regions investigated our data indicate a minor role of methylation of JAK2 negative regulators for the clinical course of ET...
- In vitro detection of methylated DNA via recombinant protein MBD2bMathilde Födermayr
Ist Department of Internal Medicine, Elisabethinen Hospital Linz, Fadingerstrasse 1, Linz, Austria
Mol Biol Rep 36:1859-62. 2009..We were able to show that these functional recombinant proteins bind to unilaterally and symmetrically methylated oligonucleotides and genomic DNA in vitro and thus can be used in various detection assays...
- Immunodetection arrayJohannes Pröll
Red Cross Transfusion Service of Upper Austria, Linz and Elisabethinen Hospital, 1st Department of Internal Medicine, Linz, Austria
Methods Mol Biol 507:45-54. 2009..These methodological improvements allow for the direct detection of 5' mC in genomic DNA hybridized to microarrays without prior PCR amplification with high analytical sensitivity...
- Ultra-sensitive immunodetection of 5'methyl cytosine for DNA methylation analysis on oligonucleotide microarraysJohannes Pröll
Elisabethinen Hospital, 1st Department of Internal Medicine Fadingerstrasse 1, A 4010 Linz, Austria
DNA Res 13:37-42. 2006..Thus, this novel technique can potentially be used for DNA methylation analysis in various scientific fields...