Research Topics
| W DimpfelSummaryCountry: Austria Publications
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Detail Information
Publications
Validation of an EEG-derived spectral frequency index (SFx) for continuous monitoring of sleep depth in humansW Dimpfel
Pro Science Private Research Clinic GmbH med Forschung und Entwicklung, Kurt Schumacher Strasse 9, D 35440 Linden, Germany
Eur J Med Res 3:453-60. 1998..79 indicating a substantial matching between the manually staged score and the SFx. We therefore conclude that the SFx is a suitable and objective indicator of sleep depth in humans...
Evidence for neuronal dysfunction in migraine: concurrence between specific qEEG findings and clinical drug response--a retrospective analysis-B Vonderheid-Guth
Pro Science Private Research Clinic GmbH, Kurt Schumacher Str 9, D 35440 Linden, Germany
Eur J Med Res 5:473-83. 2000..The aim of this analysis was to verify objective correlates of the clinical improvement of migraine in patients by means of quantitative topographical EEG (qEEG)...
Efficacy of dimethylaminoethanol (DMAE) containing vitamin-mineral drug combination on EEG patterns in the presence of different emotional statesW Dimpfel
Pro Science, Private Research Clinic GmbH med Forschung und Entwicklung, Kurt Schumacher Str 9, D 35440 Linden, Germany
Eur J Med Res 8:183-91. 2003....
Preclinical data base of pharmaco-specific rat EEG fingerprints (tele-stereo-EEG)W Dimpfel
Pro Science Research Clinic GmbH med Forschung und Entwicklung, Kurt Schumacher Str 9, D 35440 Linden, Germany
Eur J Med Res 8:199-207. 2003..Finally the recognition of new indications of already launched drugs not only becomes feasible but has resulted in filing of new indication patents...
Gender difference in electrical brain activity during presentation of various film excerpts with different emotional contentW Dimpfel
Pro Science Research Clinic GmbH med Forschung und Entwicklung, Kurt Schumacher Str 9, D 35440 Linden, Germany
Eur J Med Res 8:192-8. 2003..The data are further proof that recording the computer aided quantitative EEG is a very fruitful and promising approach in psychophysiology...
Source density analysis of functional topographical EEG: monitoring of cognitive drug actionW Dimpfel
Pro Science Private Research Institute GmbH, Kurt Schumacher Str 9, Linden D 35440, Germany
Eur J Med Res 1:283-90. 1996..A second perspective arises from the fact that it should be possible to recognize mental impairments at a very early stage by using this method, thus providing the possibility of an early treatment...
Functional imaging of headache - first steps in an objective quantitative classification of migraineS Sauer
Pro Science Private Research Institute GmbH, med Forschung und Entwicklung, Kurt Schumacher Str 9, Linden D 35440, Germany
Eur J Med Res 2:367-76. 1997..Furthermore, a decrease in alpha power neighbouring the focus was found in 18 patients and a contralateral reduction of alpha power was seen in 16 patients. No difference was detected between migraine with aura and migraine without aura...
Pharmacodynamic properties of St. John's wort-A single blind neurophysiological study in healthy subjects comparing two commercial preparationsW Dimpfel
Pro Science Private Research Clinic GmbH, Kurt Schumacher Str 9, D 35440 Linden, Germany
Eur J Med Res 4:303-12. 1999..In summary quantitative EEG proved to be able to discriminate between different extracts of St. John's wort with respect to time of effect and profile changes on neuronal communication structure...
Effects of lozenge containing lavender oil, extracts from hops, lemon balm and oat on electrical brain activity of volunteersW Dimpfel
NeuroCode AG, Kurt Schumacher Strasse 9, D 35440 Linden, Germany
Eur J Med Res 9:423-31. 2004..The data are further proof that recording computer aided quantitative EEG is a very fruitful and promising approach in psychophysiology...
Characterization of atypical antipsychotic drugs by a late decrease of striatal alpha1 spectral power in the electropharmacogram of freely moving ratsW Dimpfel
Justus Liebig University Giessen, Hessen, Germany
Br J Pharmacol 152:538-48. 2007..The present investigation was undertaken to investigate the difference between atypical and typical antipsychotic drugs...
Neurophysiological characterization of a functionally active drink containing extracts of ginkgo and ginseng by source density analysis of the human EEGW Dimpfel
Justus Liebig University of Giessen, D 35392 Giessen, Germany
Nutr Neurosci 9:213-24. 2006..3 ms) as well as increases of amplitude (from 2.07 to 3.95 microV) of the auditory P300 potential at the electrode position Pz point to a possible improvement of attention, however, the difference did not reach statistical significance...
Central action of a fixed Valerian-hops extract combination (Ze 91019) in freely moving ratsW Dimpfel
, Giessen, Germany
Eur J Med Res 11:496-500. 2006..The results are therefore in line with the view that the fixed extract combination Ze 91019 works as an adenosine agonist via inhibition of cholinergic transmission leading to sedation and sleep...
Effects of tolterodine, trospium chloride, and oxybutynin on the central nervous systemA Todorova
Pro Science Private Research Clinic GmbH, Kurt-Schumacher-Str. 9, D-35440 Linden, Germany
J Clin Pharmacol 41:636-44. 2001..The minimal qEEG changes observed with tolterodine and trospium chloride reflect most probably a rebound message from the peripheral target organs. Prescription of oxybutynin thus implicates a higher risk of CNS side effects...
Description of healthy and disturbed sleep by means of the spectral frequency index (SFx) - a retrospective analysisN Hammer
Pro Science Private Research Clinic GmbH, Linden, Germany
Eur J Med Res 6:333-44. 2001..CONCLUSIONS: The main advantage of this method in comparison to the visual sleep scoring system is that the depth of sleep is assessed objectively and described continuously...
Source density analysis of the human EEG after ingestion of a drink containing decaffeinated extract of green tea enriched with L-theanine and theogallinW Dimpfel
Justus Liebig University of Giessen, D 35392 Giessen, Germany
Nutr Neurosci 10:169-80. 2007..Thus, decaffeinated extract of green tea still has a stimulating effect despite the lack of caffeine presumably due to its high content in L-theanine and theogallin as found in preclinical experiments...
