Research Topics
| Gerald GartlehnerSummaryAffiliation: Danube University Krems Country: Austria Publications
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Detail Information
Publications
The general and comparative efficacy and safety of duloxetine in major depressive disorder: a systematic review and meta-analysisGerald Gartlehner
Department for Evidence based Medicine and Clinical Epidemiology, Danube University Krems, Krems, Austria
Drug Saf 32:1159-73. 2009..Second-generation antidepressants dominate the management of patients with major depressive disorder (MDD). Evidence on the general and comparative benefits and harms is still accruing...
[Balancing benefits and harms of population-based interventions, using the example of cancer screening]Gerald Gartlehner
Department für Evidenzbasierte Medizin und Klinische Epidemiologie, Donau Universität Krems Österreich
Z Evid Fortbild Qual Gesundhwes 105:176-82. 2011..Studies, however, indicate that the prerequisite for informed decision making, namely objective and balanced information about benefits and harms, is often missing...
How should primary care doctors select which antidepressants to administer?Gerald Gartlehner
Department of Evidence Based Medicine and Clinical Epidemiology, Danube University, Karl Dorrek Strasse 30, 3500, Krems, Austria
Curr Psychiatry Rep 14:360-9. 2012..This article summarizes the best available evidence regarding comparative benefits and harms of second-generation antidepressants for treating depressive disorders...
Clinical heterogeneity in systematic reviews and health technology assessments: synthesis of guidance documents and the literatureGerald Gartlehner
Danube University, Krems
Int J Technol Assess Health Care 28:36-43. 2012..The aim of this study was to synthesize best practices for addressing clinical heterogeneity in systematic reviews and health technology assessments (HTAs)...
Comparative benefits and harms of second-generation antidepressants for treating major depressive disorder: an updated meta-analysisGerald Gartlehner
Danube University, Krems, Austria
Ann Intern Med 155:772-85. 2011..Second-generation antidepressants dominate the management of major depressive disorder (MDD), but evidence on the comparative benefits and harms of these agents is contradictory...
Direct versus indirect comparisons: a summary of the evidenceGerald Gartlehner
Danube University, Krems, Austria
Int J Technol Assess Health Care 24:170-7. 2008..The aim of this study was to provide a comprehensive summary and interpretation of the current evidence on the use and validity of statistical methods to conduct indirect comparisons of treatment effects...
Differences in efficacy and safety of pharmaceutical treatments between men and women: an umbrella reviewGerald Gartlehner
Department for Evidence based Medicine and Clinical Epidemiology, Danube University Krems, Krems, Austria
PLoS ONE 5:e11895. 2010..The available body of evidence, however, was limited in quality and quantity, confining the range and certainty of our conclusions...
The effect of study sponsorship on a systematically evaluated body of evidence of head-to-head trials was modest: secondary analysis of a systematic reviewGerald Gartlehner
Department of Evidence Based Medicine and Clinical Epidemiology, Danube University, Krems, Austria
J Clin Epidemiol 63:117-25. 2010..The objective of this study was to determine the effect of industry bias in a systematically reviewed body of evidence of head-to-head trials...
Comparative risk for harms of second-generation antidepressants : a systematic review and meta-analysisGerald Gartlehner
Department for Evidence based Medicine and Clinical Epidemiology, Danube University Krems, Krems, Austria
Drug Saf 31:851-65. 2008..However, a comprehensive assessment of both benefits and harms is crucial to evaluate the net benefit...
Comparative benefits and harms of second-generation antidepressants: background paper for the American College of PhysiciansGerald Gartlehner
Danube University, Krems, Austria
Ann Intern Med 149:734-50. 2008..Second-generation antidepressants dominate the management of major depressive disorder, dysthymia, and subsyndromal depression. Evidence on the comparative benefits and harms is still accruing...
Assessment of adverse effects and applicability--two areas not (yet) covered adequately in Cochrane reportsGerald Gartlehner
Danube University, Krems, Austria
Z Evid Fortbild Qual Gesundhwes 102:497-502. 2008....
Inadequate reporting of trials compromises the applicability of systematic reviewsGerald Gartlehner
Department for Evidence based Medicine and Clinical Epidemiology, Danube University, Krems, Austria
Int J Technol Assess Health Care 25:323-30. 2009..This study aimed to determine whether information reported in studies included in systematic reviews was adequate enough to assess their applicability...
Comparative effectiveness of second-generation antidepressants for accompanying anxiety, insomnia, and pain in depressed patients: a systematic reviewKylie J Thaler
Danube University Krems, Krems, Austria
Depress Anxiety 29:495-505. 2012....
[Clinical outcomes, health-related quality of life, and cost-effectiveness of a 6-month community- based lifestyle program for adults at increased cardiovascular risk in lower Austria]Ursula Reichenpfader
Department für Evidenzbasierte Medizin und Klinische Epidemiologie, Donau Universität Krems, Krems, Osterreich
Wien Med Wochenschr 162:321-9. 2012..To investigate lifestyle intervention effects and cost-effectiveness of a structured 6-month exercise and nutrition program for individuals at high risk for cardiovascular disease...
Second-generation antidepressants for seasonal affective disorderKylie Thaler
Department for Evidence based Medicine and Clinical Epidemiology, Danube University Krems, Krems, Austria
Cochrane Database Syst Rev 12:CD008591. 2011..Seasonal affective disorder (SAD) is a seasonal pattern of recurrent depressive episodes that is often treated with second-generation antidepressants (SGAs), light therapy or psychotherapy...
[Austrian patient information materials on PSA-screening do not meet international evidence-based standards]Michaela Strobelberger
Department für Evidenzbasierte Medizin und Klinische Epidemiologie, Donau Universität, Krems, Austria
Wien Med Wochenschr 161:89-98. 2011..The aim of this paper was to evaluate all in Austria available patient information materials on PSA-screening with regard to their evidence-based content and their potential to facilitate informed decision-making...
Antidepressants for the treatment of abdominal pain-related functional gastrointestinal disorders in children and adolescentsAngela Kaminski
Department for Evidence based Medicine and Clinical Epidemiology, Danube University Krems, Dr Karl Dorrek Strasse 30, Krems, Austria, 3500
Cochrane Database Syst Rev 7:CD008013. 2011..To date, the evidence on the benefits and harms of antidepressants for the treatment of abdominal pain-related FGIDs has not been assessed systematically...
Sentinel lymph node dissection only versus complete axillary lymph node dissection in early invasive breast cancer: a systematic review and meta-analysisAnna Glechner
Danube University, Department for Evidence based Medicine and Clinical Epidemiology, Austria
Eur J Cancer 49:812-25. 2013..The aim of this review was to systematically assess the evidence on the comparative benefits and harms of ALND versus SLND for sentinel node positive breast cancer patients...
Efficacy and safety of anakinra for the treatment of rheumatoid arthritis: an update of the Oregon Drug Effectiveness Review ProjectKylie Thaler
Department for Evidence based Medicine and Clinical Epidemiology, Danube University Krems, Krems, Austria
Biologics 3:485-98. 2009..To systematically review the general and comparative efficacy and safety of anakinra for rheumatoid arthritis...
Bach Flower Remedies for psychological problems and pain: a systematic reviewKylie Thaler
Department for Evidence based Medicine and Clinical Epidemiology, Danube University, Krems, A 3500, Austria
BMC Complement Altern Med 9:16. 2009..We assessed whether Bach Flower Remedies (BFRs) are safe and efficacious for these indications by performing a systematic review of the literature...
Semi-automating the manual literature search for systematic reviews increases efficiencyAndrea L Chapman
Department for Evidence based Medicine and Clinical Epidemiology, Danube University Krems, Krems, Austria
Health Info Libr J 27:22-7. 2010....
