Research Topics
| P ZimmetSummaryCountry: Australia Publications
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Detail Information
Publications
Preventing Type 2 diabetes and the dysmetabolic syndrome in the real world: a realistic viewP Zimmet
International Diabetes Institute, Caulfield and Monash University, Victoria, Australia
Diabet Med 20:693-702. 2003..Longer-term follow-up studies will also clarify whether both lifestyle and pharmacological interventions actually prevent Type 2 diabetes, or merely delay its onset...
Genotype, obesity and cardiovascular disease--has technical and social advancement outstripped evolution?P Zimmet
International Diabetes Institute, Caulfield, Victoria, Australia
J Intern Med 254:114-25. 2003..If lifestyle measures fail, then pharmacological intervention may be necessary. For this, novel agents such as dual PPARalpha/gamma agonists may be the therapy of the future...
Serum leptin concentration, obesity, and insulin resistance in Western Samoans: cross sectional studyP Zimmet
International Diabetes Institute, Victoria, Australia
BMJ 313:965-9. 1996..The relation with insulin independent of body mass index suggests a possible role for leptin in insulin resistance or hyperinsulinaemia...
Hyperleptinaemia: the missing link in the, metabolic syndrome?M de Courten
International Diabetes Institute, Melbourne, Australia
Diabet Med 14:200-8. 1997....
Leptin predicts the development of diabetes in Mauritian men, but not women: a population-based studyS Soderberg
International Diabetes Institute, Melbourne, Australia
Int J Obes (Lond) 31:1126-33. 2007..To determine if levels of the adipocyte-derived hormone, leptin, predict the development of type 2 diabetes...
Increasing prevalence of Type 2 diabetes mellitus in all ethnic groups in MauritiusS Soderberg
International Diabetes Institute, Melbourne, Australia
Diabet Med 22:61-8. 2005..To describe the prevalence of different stages of glucose intolerance in a population from Mauritius followed over 11 years...
Risk factors for coronary heart disease in a population with a high prevalence of obesity and diabetes: a case-control study of the Polynesian population of Western SamoaS Wahi
Baker Medical Research Institute, Melbourne, Victoria, Australia
J Cardiovasc Risk 4:173-8. 1997....
Etiology of the metabolic syndrome: potential role of insulin resistance, leptin resistance, and other playersP Zimmet
International Diabetes Institute, Melbourne, Australia
Ann N Y Acad Sci 892:25-44. 1999....
Global and societal implications of the diabetes epidemicP Zimmet
International Diabetes Institute, 260 Kooyong Road, Caulfield, Victoria 3162, Australia
Nature 414:782-7. 2001..The prevention of diabetes and control of its micro- and macrovascular complications will require an integrated, international approach if we are to see significant reduction in the huge premature morbidity and mortality it causes...
Genetic variation in SH3-domain GRB2-like (endophilin)-interacting protein 1 has a major impact on fat massN Cummings
Genomics and Systems Biology, Baker IDI Heart and Diabetes Institute, Melbourne, Victoria, Australia
Int J Obes (Lond) 36:201-6. 2012..The purpose of this study was to assess the role of genetic variation in SGIP1 in human disease...
Epidemiology of childhood type 2 diabetes in the developing worldR Singh
International Diabetes Institute, Melbourne, Australia
Pediatr Diabetes 5:154-68. 2004..These are of relevance in both developed and developing nations...
Decorin is a secreted protein associated with obesity and type 2 diabetesK Bolton
Metabolic Research Unit, School of Exercise and Nutrition Sciences, Deakin University, Waurn Ponds, Victoria, Australia
Int J Obes (Lond) 32:1113-21. 2008..To characterize the expression of the small leucine-rich glycoprotein decorin in adipose tissue...
Effects of beacon administration on energy expenditure and substrate utilisation in Psammomys obesus (Israeli sand rats)K Walder
Metabolic Research Unit, School of Health Sciences, Deakin University, Geelong, Victoria, Australia
Int J Obes Relat Metab Disord 25:1281-5. 2001..To investigate whether beacon administration affects substrate utilisation, physical activity levels or energy expenditure in Psammomys obesus...
Bariatric surgery: an IDF statement for obese Type 2 diabetesJ B Dixon
Baker IDI Heart and Diabetes Institute, Melbourne, Victoria, Australia
Surg Obes Relat Dis 7:433-47. 2011..National guidelines for bariatric surgery need to be developed for people with Type 2 diabetes and a BMI of 35 kg/m(2) or more...
High incidence of type 2 diabetes and increasing conversion rates from impaired fasting glucose and impaired glucose tolerance to diabetes in MauritiusS Soderberg
International Diabetes Institute, Melbourne, Victoria, Australia
J Intern Med 256:37-47. 2004..Glucose tolerance was classified according to WHO 1999 criteria...
Crucial points at diagnosis. Type 2 diabetes or slow type 1 diabetesP Zimmet
International Diabetes Institute, Melbourne, Australia
Diabetes Care 22:B59-64. 1999..3% of those not on insulin at 6 years. Antibodies to GAD indicate an underlying autoimmune process and have a high positive predictive value for type 1 diabetes and future insulin dependency in adults...
The burden of type 2 diabetes: are we doing enough?P Zimmet
International Diabetes Institute, Caulfield, Victoria, Australia
Diabetes Metab 29:6S9-18. 2003..Above all, intervention is needed today...
Bariatric surgery: an IDF statement for obese Type 2 diabetesJ B Dixon
Baker IDI Heart and Diabetes Institute, 99 Commercial Road, Melbourne, Victoria, Australia
Diabet Med 28:628-42. 2011..National guidelines for bariatric surgery need to be developed for people with Type 2 diabetes and a BMI of 35 kg/m(2) or more...
Addressing the insulin resistance syndrome: a role for the thiazolidinedionesP Zimmet
International Diabetes Institute, Caulfield, Victoria, Australia
Trends Cardiovasc Med 12:354-62. 2002....
Elevated hypothalamic beacon gene expression in Psammomys obesus prone to develop obesity and type 2 diabetesK Walder
Metabolic Research Unit, School of Health Sciences, Deakin University, Waurn Ponds, Victoria, Australia
Int J Obes Relat Metab Disord 26:605-9. 2002..In addition, effects of dietary energy composition on beacon gene expression were investigated in diabetes-prone P. obesus...
Effects of ramipril and rosiglitazone on cardiovascular and renal outcomes in people with impaired glucose tolerance or impaired fasting glucose: results of the Diabetes REduction Assessment with ramipril and rosiglitazone Medication (DREAM) trialG R Dagenais
Laval University Heart and Lung Institute, 2725 Chemin Ste Foy, Quebec, Quebec City, Canada
Diabetes Care 31:1007-14. 2008..We determined the effects of ramipril and rosiglitazone on combined and individual CVD and renal outcomes in people with IGT and/or IFG in the Diabetes REduction Assessment With ramipril and rosiglitazone Medication (DREAM) trial...
Ethnic comparisons of the cross-sectional relationships between measures of body size with diabetes and hypertensionR Huxley
The George Institute for International Health, Sydney, NSW, Australia
Obes Rev 9:53-61. 2008....
Diet, nutrition and the prevention of type 2 diabetesN P Steyn
Chronic Diseases of Lifestyle Unit, Medical Research Council MRC, Tygerberg, South Africa
Public Health Nutr 7:147-65. 2004..The overall objective of this study was to evaluate and provide evidence and recommendations on current published literature about diet and lifestyle in the prevention of type 2 diabetes...
Islet autoimmunity status in Asians with young-onset diabetes (12-40 years): association with clinical characteristics, beta cell function and cardio-metabolic risk factorsA C Thai
Department of Medicine, Yong Loo Lin School of Medicine, National University of Singapore, 5 Lower Kent Ridge Road, 119074 Singapore, Singapore
Diabetes Res Clin Pract 80:224-30. 2008..Regardless of autoimmunity status, the cardio-metabolic risk factors, in particular atherogenic dyslipidaemia, hypertension and albuminuria were common in our patients with young-onset diabetes...
International Diabetes Federation: a consensus on Type 2 diabetes preventionK G M M Alberti
Department of Endocrinology and Metabolic Medicine, St Mary s Hospital, London, UK
Diabet Med 24:451-63. 2007..In addition, it is important that all activities are tailored to the specific local situation. Further information on the prevention of diabetes can be found on the IDF website: http://www.idf.org/prevention...
Impaired glucose tolerance and impaired fasting glycaemia: the current status on definition and interventionN Unwin
Diabetes and Metabolism, School of Clinical Medical Sciences, University of New Castle, UK
Diabet Med 19:708-23. 2002..4. Life style interventions are highly effective in delaying or preventing the onset of diabetes in people with IGT and may reduce CVD and total mortality, but the latter requires formal testing...
Latent autoimmune diabetes in adults (LADA)--more than a nameL Groop
Department of Clinical Sciences, Diabetes and Endocrinology, Lund University, University Hospital Malmo, 20502, Malmo, Sweden
Diabetologia 49:1996-8. 2006
Improving glucose management: ten steps to get more patients with type 2 diabetes to glycaemic goalS Del Prato
University of Pisa, Italy
Int J Clin Pract 59:1345-55. 2005..Implementation of these recommendations should reduce the risk of diabetes-related complications, improve patient quality of life and impact more effectively on the increasing healthcare cost related to diabetes...
IA-2 antibody prevalence and risk assessment of early insulin requirement in subjects presenting with type 2 diabetes (UKPDS 71)G F Bottazzo
Scientific Directorate, , Scientific Institute, Rome, Italy
Diabetologia 48:703-8. 2005..The measurement of IA-2betaA does not provide additional information...
The mitochondrial rhomboid protease PSARL is a new candidate gene for type 2 diabetesK Walder
Metabolic Research Unit, School of Health Sciences, Deakin University, Pigdons Road, Waurn Ponds, 3217, Australia
Diabetologia 48:459-68. 2005..This study aimed to identify genes that are expressed in skeletal muscle, encode proteins with functional significance in mitochondria, and are associated with type 2 diabetes...
Metabolic, immunological and clinical characteristics in newly diagnosed Asian diabetes patients aged 12-40 yearsC Y Pan
Chinese PLA General Hospital, Beijing, China
Diabet Med 21:1007-13. 2004..To describe the clinical, biochemical and immunological characteristics of young-onset diabetes in Asia...
