Felicia Y T Yap
- Advanced glycation end products as environmental risk factors for the development of type 1 diabetesFelicia Y T Yap
BakerIDI Diabetes and Heart Institute, Melbourne, Victoria, Australia
Curr Drug Targets 13:526-40. 2012....
- Advanced glycation end products are direct modulators of β-cell functionMelinda T Coughlan
Division of Diabetes Complications, Diabetes and Metabolism Division, Baker IDI Heart and Diabetes Institute, Melbourne, Australia
Diabetes 60:2523-32. 2011..Excess accumulation of advanced glycation end products (AGEs) contributes to aging and chronic diseases. We aimed to obtain evidence that exposure to AGEs plays a role in the development of type 1 diabetes (T1D)...
- Deletion of bone-marrow-derived receptor for AGEs (RAGE) improves renal function in an experimental mouse model of diabetesGreg Tesch
Department of Nephrology, Monash Medical Centre, Monash Health, Clayton, Melbourne, Vic, Australia
Diabetologia 57:1977-85. 2014..The aim of this study was to determine whether deletion of RAGE from bone-marrow-derived cells influences the pathogenesis of experimental diabetic nephropathy...
- Effects of high-density lipoprotein elevation with cholesteryl ester transfer protein inhibition on insulin secretionAndrew L Siebel
Baker IDI Heart and Diabetes Institute, Melbourne, Australia
Circ Res 113:167-75. 2013..High-density lipoprotein cholesterol elevation via cholesteryl ester transfer protein (CETP) inhibition represents a novel therapy for atherosclerosis, which also may have relevance for type 2 diabetes mellitus...
- Inhibition of NADPH oxidase prevents advanced glycation end product-mediated damage in diabetic nephropathy through a protein kinase C-alpha-dependent pathwayVicki Thallas-Bonke
JDRF Albert Einstein Centre for Diabetes Complications, Diabetes and Metabolism Division, Baker Medical Research Institute, P O Box 6492, St Kilda Rd, Central, Melbourne, Victoria, Australia
Diabetes 57:460-9. 2008..Since NADPH oxidase activation is closely linked to other putative pathways, its interaction with changes in protein kinase C (PKC) and increased advanced glycation was examined...