Colin J R Stewart

Summary

Affiliation: Western Australia
Country: Australia

Publications

  1. doi An immunohistochemical and molecular analysis of problematic and unclassified ovarian sex cord-stromal tumors
    Colin J R Stewart
    Department of Histopathology, King Edward Memorial Hospital, Perth, Western Australia, Australia School for Women s and Infants Health, University of Western Australia, Crawley, Australia Electronic address
    Hum Pathol 44:2774-81. 2013
  2. doi Transtubal spread of endometrial carcinoma: correlation of intra-luminal tumour cells with tumour grade, peritoneal fluid cytology, and extra-uterine metastasis
    C J R Stewart
    Department of Histopathology, King Edward Memorial Hospital, Perth, WA, Australia
    Pathology 45:382-7. 2013
  3. doi Epithelial-mesenchymal transition in carcinomas of the female genital tract
    Colin J R Stewart
    Departments of Histopathology, King Edward Memorial Hospital, Perth, Australia
    Histopathology 62:31-43. 2013
  4. doi Mullerian carcinosarcoma arising in the cecum associated with florid vascular proliferation/glomeruloid microvascular proliferation
    Colin J R Stewart
    Department of Histopathology, University of Western Australia, Perth, Western Australia, Australia
    Int J Gynecol Pathol 32:38-43. 2013
  5. doi β-Catenin and E-cadherin expression in stage I adult-type granulosa cell tumour of the ovary: correlation with tumour morphology and clinical outcome
    Colin J R Stewart
    Department of Histopathology, King Edward Memorial Hospital, Bagot Rd, Subiaco, Perth, WA 6008, Australia
    Histopathology 62:257-66. 2013
  6. doi Fallopian tube metastases of non-gynaecological origin: a series of 20 cases emphasizing patterns of involvement including intra-epithelial spread
    Colin J R Stewart
    Department of Pathology, King Edward Memorial Hospital, Perth, Western Australia, Australia
    Histopathology 60:E106-14. 2012
  7. doi KRAS mutations in ovarian low-grade endometrioid adenocarcinoma: association with concurrent endometriosis
    Colin J R Stewart
    Department of Histopathology, King Edward Memorial Hospital, Perth 6008, Western Australia
    Hum Pathol 43:1177-83. 2012
  8. doi Fascin expression in endocervical neoplasia: correlation with tumour morphology and growth pattern
    Colin J R Stewart
    Department of Histopathology, King Edward Memorial Hospital, Perth, Western Australia, Australia
    J Clin Pathol 65:213-7. 2012
  9. doi Micro-anatomical variation in cellular proliferation in endometrial adenocarcinoma, and inverse correlation between Ki67 and cytokeratin 7 expression
    Colin J R Stewart
    Department of Histopathology, King Edward Memorial Hospital, University of Western Australia, Perth, Australia
    Histopathology 57:46-54. 2010
  10. doi Tubulo-squamous vaginal polyp with basaloid epithelial differentiation
    Colin J R Stewart
    Department of Histopathology, King Edward Memorial Hospital, Perth 6008, Australia
    Int J Gynecol Pathol 28:563-6. 2009

Collaborators

Detail Information

Publications45

  1. doi An immunohistochemical and molecular analysis of problematic and unclassified ovarian sex cord-stromal tumors
    Colin J R Stewart
    Department of Histopathology, King Edward Memorial Hospital, Perth, Western Australia, Australia School for Women s and Infants Health, University of Western Australia, Crawley, Australia Electronic address
    Hum Pathol 44:2774-81. 2013
    ..Immunohistochemical profiles overlap with those of better categorized SCST, but staining may be focal or negative emphasizing the requirement for antibody panels in diagnostic assessment. ..
  2. doi Transtubal spread of endometrial carcinoma: correlation of intra-luminal tumour cells with tumour grade, peritoneal fluid cytology, and extra-uterine metastasis
    C J R Stewart
    Department of Histopathology, King Edward Memorial Hospital, Perth, WA, Australia
    Pathology 45:382-7. 2013
    ..To assess the significance of intra-luminal tumour cells (ILTC) within the fallopian tubes of patients with endometrial carcinoma, with emphasis on high grade histological subtypes...
  3. doi Epithelial-mesenchymal transition in carcinomas of the female genital tract
    Colin J R Stewart
    Departments of Histopathology, King Edward Memorial Hospital, Perth, Australia
    Histopathology 62:31-43. 2013
    ..Diagnostic histopathologists are ideally placed to critically evaluate the role of EMT in gynaecological and other types of malignancy...
  4. doi Mullerian carcinosarcoma arising in the cecum associated with florid vascular proliferation/glomeruloid microvascular proliferation
    Colin J R Stewart
    Department of Histopathology, University of Western Australia, Perth, Western Australia, Australia
    Int J Gynecol Pathol 32:38-43. 2013
    ..Recognition of these tumor-associated vasoformative lesions may be important in view of their adverse prognostic association and may become therapeutically relevant considering the current developments in angiogenesis inhibitors...
  5. doi β-Catenin and E-cadherin expression in stage I adult-type granulosa cell tumour of the ovary: correlation with tumour morphology and clinical outcome
    Colin J R Stewart
    Department of Histopathology, King Edward Memorial Hospital, Bagot Rd, Subiaco, Perth, WA 6008, Australia
    Histopathology 62:257-66. 2013
    ..To study E-cadherin and β-catenin expression in stage I adult-type granulosa cell tumours (AGCTs) and correlate the findings with tumour morphology and clinical outcome...
  6. doi Fallopian tube metastases of non-gynaecological origin: a series of 20 cases emphasizing patterns of involvement including intra-epithelial spread
    Colin J R Stewart
    Department of Pathology, King Edward Memorial Hospital, Perth, Western Australia, Australia
    Histopathology 60:E106-14. 2012
    ..To determine the frequency and distribution of Fallopian tube involvement in patients with ovarian metastases of non-gynaecological origin...
  7. doi KRAS mutations in ovarian low-grade endometrioid adenocarcinoma: association with concurrent endometriosis
    Colin J R Stewart
    Department of Histopathology, King Edward Memorial Hospital, Perth 6008, Western Australia
    Hum Pathol 43:1177-83. 2012
    ....
  8. doi Fascin expression in endocervical neoplasia: correlation with tumour morphology and growth pattern
    Colin J R Stewart
    Department of Histopathology, King Edward Memorial Hospital, Perth, Western Australia, Australia
    J Clin Pathol 65:213-7. 2012
    ..In this study fascin expression was assessed in adenocarcinoma in situ (ACIS) and invasive adenocarcinoma of the endocervix, and the results were correlated with tumour growth patterns (papillary, glandular or infiltrative)...
  9. doi Micro-anatomical variation in cellular proliferation in endometrial adenocarcinoma, and inverse correlation between Ki67 and cytokeratin 7 expression
    Colin J R Stewart
    Department of Histopathology, King Edward Memorial Hospital, University of Western Australia, Perth, Australia
    Histopathology 57:46-54. 2010
    ..To investigate micro-anatomical variations in proliferative activity within uterine endometrioid adenocarcinoma with particular emphasis on tumour areas comprising microcystic, elongated and fragmented ('MELF') glands...
  10. doi Tubulo-squamous vaginal polyp with basaloid epithelial differentiation
    Colin J R Stewart
    Department of Histopathology, King Edward Memorial Hospital, Perth 6008, Australia
    Int J Gynecol Pathol 28:563-6. 2009
    ..This feature has not been recorded previously in tubulo-squamous polyp and potentially could create diagnostic difficulty with other lesions such as basal cell/adenoid basal carcinoma or small-cell neuroendocrine carcinoma...
  11. doi Comparison of proliferation indices in primary adult-type granulosa cell tumors of the ovary and their corresponding metastases: an analysis of 14 cases
    Colin J R Stewart
    Department of Histopathology, King Edward Memorial Hospital, Perth, Western Australia 6008, Australia
    Int J Gynecol Pathol 28:423-31. 2009
    ..Therefore, data derived from the analysis of primary GCT may not always be applicable to recurrent tumors. These findings may have implications for management including the potential response of GCT to adjuvant therapies...
  12. ncbi Intraoperative assessment of ovarian tumors: a 5-year review with assessment of discrepant diagnostic cases
    Colin J R Stewart
    Department of Histopathology, King Edward Memorial Hospital, Subiaco, Western Australia
    Int J Gynecol Pathol 25:216-22. 2006
    ..This study confirms that ovarian frozen section is a generally reliable technique, but there are problematic areas, particularly involving the assessment of borderline tumors...
  13. doi KRAS mutation and microsatellite instability in endometrial adenocarcinomas showing MELF-type myometrial invasion
    C J R Stewart
    Department of Histopathology, King Edward Memorial Hospital, Subiaco, Australia
    J Clin Pathol 63:604-8. 2010
    ..Immunohistochemical studies have suggested that MELF-type changes represent an epithelial-mesenchymal transition which has been associated with KRAS activation in various tumours...
  14. doi Galectin-3 expression in uterine endometrioid adenocarcinoma: comparison of staining in conventional tumor glands and in areas of MELF pattern myometrial invasion
    Colin J R Stewart
    Department of Histopathology, King Edward Memorial Hospital, Perth, Western Australia, Australia
    Int J Gynecol Pathol 29:555-61. 2010
    ..As MELF pattern invasion is associated with the loss of galectin-3 expression, there may be implications for the use of galectin inhibitors in the treatment of endometrial carcinomas and other malignancies...
  15. doi CD147 (EMMPRIN) and matrix metalloproteinase-2 expression in uterine endometrioid adenocarcinoma
    C J R Stewart
    Department of Histopathology, King Edward Memorial Hospital, Perth, Western Australia, Australia
    Pathol Res Pract 207:30-6. 2011
    ..It is likely that stromal MMP2 plays a role in potentiating invasion in these tumors but this may be regulated by factors other than CD147...
  16. doi Correlation between invasive pattern and immunophenotypic alterations in endocervical adenocarcinoma
    Colin J R Stewart
    Department of Histopathology, King Edward Memorial Hospital, Perth, WA, Australia
    Histopathology 58:720-8. 2011
    ..To assess the immunophenotypic changes associated with epithelial-mesenchymal transition (EMT) in endocervical adenocarcinoma, and correlate the findings with tumour morphology including growth pattern...
  17. doi Fascin expression in low-grade uterine endometrioid adenocarcinoma: correlation with microcystic, elongated and fragmented (MELF)-type alteration at the deep invasive margin
    Colin J R Stewart
    Department of Histopathology, King Edward Memorial Hospital, Bagot Road, Subiaco, Perth, WA 6008, Australia
    Histopathology 59:73-80. 2011
    ..Therefore, fascin immunoreactivity was investigated in a series of endometrial carcinomas specifically comparing expression in conventional tumour areas, foci of MELF-type invasion and in stromal elements...
  18. doi Cytokeratin 19 expression in normal endometrium and in low-grade endometrioid adenocarcinoma of the endometrium
    Colin J R Stewart
    Department of Histopathology, King Edward Memorial Hospital, Perth, Western Australia
    Int J Gynecol Pathol 30:484-91. 2011
    ..Further studies are required to determine the mechanism and biologic significance of localized alterations in CK19 expression within endometrial neoplasms...
  19. doi Immunophenotypic features of MELF pattern invasion in endometrial adenocarcinoma: evidence for epithelial-mesenchymal transition
    Colin J R Stewart
    Department of Histopathology, King Edward Memorial Hospital, Perth, WA, Australia
    Histopathology 55:91-101. 2009
    ..These changes share features of epithelial-mesenchymal transition (EMT) in carcinomas arising at other sites. The aim was to compare the immunophenotypic profile of MELF-type epithelium with conventional glandular areas of EEC...
  20. doi Acquired lymphangiectasia ('lymphangioma circumscriptum') of the vulva: a report of eight cases
    C J R Stewart
    Department of Histopathology, King Edward Memorial Hospital, Perth, Western Australia, Australia
    Pathology 41:448-53. 2009
    ..To present the clinico-pathological findings of eight cases of acquired vulval lymphangiectasia (AVL) with discussion of the terminology and differential diagnosis...
  21. ncbi MELF pattern invasion in endometrial carcinoma: association with low grade, myoinvasive endometrioid tumours, focal mucinous differentiation and vascular invasion
    C J R Stewart
    Department of Histopathology, King Edward Memorial Hospital, Perth, Western Australia, Australia
    Pathology 41:454-9. 2009
    ..To investigate the frequency of microcystic, elongated and fragmented (MELF) pattern invasion in endometrial carcinoma and its association with other pathological findings...
  22. ncbi Ovarian mucinous tumour arising in mature cystic teratoma and associated with pseudomyxoma peritonei: report of two cases and comparison with ovarian involvement by low-grade appendiceal mucinous tumour
    Colin J R Stewart
    Departments of Histopathology and Gynaecological Oncology, King Edward Memorial Hospital, Perth, Western Australia
    Pathology 38:534-8. 2006
    ..In this report two further examples of this rare tumour are described, and the immunohistological phenotype including expression of MUC proteins is compared with secondary ovarian involvement by low-grade appendiceal mucinous neoplasm...
  23. ncbi Value of elastin staining in the assessment of peritoneal implants associated with ovarian serous borderline tumours
    C J R Stewart
    Department of Pathology, King Edward Memorial Hospital, Perth, Western Australia, Australia
    Histopathology 51:313-21. 2007
    ..To determine whether elastin stains aid in classifying peritoneal implants associated with ovarian serous borderline tumours (SBT)...
  24. ncbi Identification of serosal invasion and extramural venous invasion on review of Dukes' stage B colonic carcinomas and correlation with survival
    C J R Stewart
    Division of Anatomical Pathology, PathWest, Sir Charles Gairdner Hospital, Nedlands, Perth, Western Australia, Australia
    Histopathology 51:372-8. 2007
    ....
  25. pmc Mucosal endocrine cell micronests and single endocrine cells following neo-adjuvant therapy for adenocarcinoma of the distal oesophagus and oesophagogastric junction
    Colin J R Stewart
    Division of Anatomical Pathology, Sir Charles Gairdner Hospital and SJOG Pathology, Perth, Western Australia
    J Clin Pathol 60:1284-9. 2007
    ..To determine the frequency of endocrine cell micronests (ECM) and single endocrine cells (SEC) within the glandular mucosa of the distal oesophagus and oesophagogastric junction (OGJ) following neo-adjuvant therapy for adenocarcinoma...
  26. doi Detection of Y-chromosome in gonadal tumours using fluorescence in situ hybridization: diagnostic value in intersex conditions including older patients with clinically unsuspected androgen insensitivity syndrome
    C J R Stewart
    Department of Histopathology, King Edward Memorial Hospital, Perth, Western Australia, Australia
    Histopathology 52:175-82. 2008
    ....
  27. doi Use of reticulin stain in the diagnosis of intra-uterine gestation
    Colin J R Stewart
    Department of Histopathology, King Edward Memorial Hospital, Perth, Western Australia
    Pathology 40:365-71. 2008
    ..We have noted that these stromal changes may be highlighted by a simple reticulin stain; therefore, we have evaluated reticulin staining in a series of endometrial biopsy specimens from patients with intra-uterine and ectopic gestations...
  28. doi WT1 expression in endometrioid ovarian carcinoma with and without associated endometriosis
    C J R Stewart
    Department of Histopathology, King Edward Memorial Hospital, Bagot Road, Subiaco, Perth, WA 6009, Australia
    Pathology 40:592-9. 2008
    ..To determine how frequently endometrioid ovarian carcinomas (EOC) express WT1 protein, and to correlate the results with the presence of endometriosis and p53 immunoreactivity...
  29. doi Intraoperative assessment of clear cell carcinoma of the ovary
    Colin J R Stewart
    Department of Histopathology, King Edward Memorial Hospital and SJOG Pathology, Perth, Australia
    Int J Gynecol Pathol 27:475-82. 2008
    ..Review of the frozen-section slides from the CCC with discrepant intraoperative diagnoses showed features suggestive or indicative of the correct diagnosis in 7 (39%) of 18 cases...
  30. doi Extrauterine adenomyoma with atypical (symplastic) smooth muscle cells: a report of 2 cases
    Colin J R Stewart
    Department of Histopathology, King Edward Memorial Hospital, Perth, Western Australia, Australia
    Int J Gynecol Pathol 28:23-8. 2009
    ..In this report 2 cases of extrauterine adenomyoma are presented in which the smooth muscle component showed focal atypical (symplastic) cytologic appearances...
  31. doi Expression of cell cycle regulatory proteins in endometrial adenocarcinoma: variations in conventional tumor areas and in microcystic, elongated and fragmented glands
    Colin J R Stewart
    Department of Histopathology, King Edward Memorial Hospital, Perth, Western Australia, Australia
    Mod Pathol 22:725-33. 2009
    ....
  32. ncbi Accuracy of frozen section in distinguishing primary ovarian neoplasia from tumors metastatic to the ovary
    Colin J R Stewart
    Department of Histopathology, King Edward Memorial Hospital, Perth, Western Australia, Australia
    Int J Gynecol Pathol 24:356-62. 2005
    ..The simple algorithm proposed by Seidman and colleagues for assessment of ovarian mucinous tumors is helpful and can be applied to low-grade adenocarcinomas of other histological types...
  33. doi Cyclin D1, E-cadherin and beta-catenin expression in FIGO Stage IA cervical squamous carcinoma: diagnostic value and evidence for epithelial-mesenchymal transition
    Mei Hui E Koay
    Department of Histopathology, King Edward Memorial Hospital, Perth, WA, Australia
    Histopathology 61:1125-33. 2012
    ..Epithelial-mesenchymal transition (EMT) may be a mechanism of invasion in cervical neoplasia and expression of EMT-associated proteins could prove useful in this diagnostic setting...
  34. doi Is the detection of endometrial nerve fibers useful in the diagnosis of endometriosis?
    Connull Leslie
    Department of Histopathology, King Edward Memorial Hospital, Subiaco, Western Australia
    Int J Gynecol Pathol 32:149-55. 2013
    ..Pathologists and gynecologists considering this diagnostic approach should carefully consider the methodological factors that may influence its reliability...
  35. doi Value of cytology in the intraoperative assessment of ovarian tumors: a review of 402 cases and comparison with frozen section diagnosis
    Colin J R Stewart
    Department of Histopathology, King Edward Memorial Hospital, Perth, Western Australia
    Cancer Cytopathol 118:127-36. 2010
    ..In this study the accuracy of intraoperative cytology has been assessed and the results compared with frozen section diagnosis...
  36. ncbi Ovarian teratoma associated with anti-N-methyl D-aspartate receptor encephalitis: a report of 5 cases documenting prominent intratumoral lymphoid infiltrates
    Marcus Dabner
    Department of Histopathology, King Edward Memorial Hospital, Perth, Western Australia
    Int J Gynecol Pathol 31:429-37. 2012
    ..Careful histopathologic examination may be required to identify small, radiologically occult teratomas, and to demonstrate the presence of subtle neoplastic neuroglial components in teratomas associated with anti-NMDAR encephalitis...
  37. ncbi Superficial cervico-vaginal myofibroblastoma: a report of five cases
    Colin J R Stewart
    Department of Pathology, King Edward Memorial Hospital, Subiaco, Western Australia, Australia
    Pathology 37:144-8. 2005
    ..To describe the pathological and immunohistochemical features of five cases of superficial cervico-vaginal myofibroblastoma (SCVM), a recently described mesenchymal tumour affecting middle-aged and elderly females...
  38. doi Immunophenotypic analysis of ovarian endometrioid adenocarcinoma: correlation with KRAS mutation and the presence of endometriosis
    Colin J R Stewart
    Department of Pathology, King Edward Memorial Hospital, Perth School of Women s and Infants Health Centre for Applied Statistics, University of Western Australia Department of Research, Sir Charles Gairdner Hospital, Perth, Western Australia Cancer and Population Studies Group, Queensland Institute of Medical Research, Brisbane Department of Histopathology, Sullivan Nicolaides Pathology, Brisbane, Queensland, Australia
    Pathology 45:559-66. 2013
    ..The relationship between endometriosis and ovarian endometrioid adenocarcinoma (OEC) is well recognised but it is unclear whether endometriosis positive and negative OECs develop via similar pathogenetic mechanisms...
  39. doi An evaluation of the morphologic features of low-grade mucinous neoplasms of the appendix metastatic in the ovary, and comparison with primary ovarian mucinous tumors
    Colin J R Stewart
    Department of Histopathology C J R S, N M A, King Edward Memorial Hospital, Subiaco, Perth School for Women s and Infants Health C J R S, D A D, University of Western Australia, WA, Australia James Homer Wright Pathology Laboratories R H Y, Massachusetts General Hospital, and Harvard Medical School, Boston, MA
    Int J Gynecol Pathol 33:1-10. 2014
    ....
  40. doi Bilateral ovarian lymphangioma (lymphangioleiomyoma)
    Sooraj Pillai
    Department of Histopathology, King Edward Memorial Hospital, Subiaco, Western Australia
    Int J Gynecol Pathol 32:171-5. 2013
    ..Lymphangioma and lymphangioleiomyoma should be considered in the differential diagnosis of bilateral, multicystic ovarian neoplasms...
  41. doi Prognostic value of mitotic counts and Ki-67 immunoreactivity in adult-type granulosa cell tumour of the ovary
    E M Leuverink
    Department of Histopathology, King Edward Memorial Hospital, Perth, Western Australia, Australia
    J Clin Pathol 61:914-9. 2008
    ..In this study the mitotic activity and Ki-67 immunohistochemistry was assessed in a series of GCT using carefully specified methodology, and the findings were correlated with clinicopathological findings...
  42. pmc Crystalline plasma cell inclusions in helicobacter-associated gastritis
    C J R Stewart
    Division of Anatomical Pathology, PathWest, Sir Charles Gairdner Hospital, Perth, Western Australia
    J Clin Pathol 59:851-4. 2006
    ..Crystalline cytoplasmic inclusions are well documented in B cell lymphomas but have rarely been described in reactive plasmacytic infiltrates...
  43. ncbi Hormonally mediated disturbance of angiogenesis in the human endometrium after exposure to intrauterine levonorgestrel
    C Jay McGavigan
    Department of Obstetrics and Gynaecology, University of Glasgow, Glasgow Royal Infirmary, Glasgow, UK
    Hum Reprod 18:77-84. 2003
    ..The system induces inter-menstrual bleeding within the first few months after insertion. We hypothesized that this bleeding might be associated with a change in vascular development...
  44. ncbi Lymphoplasmacytic sclerosing pancreatitis: a report of two cases
    Colin J R Stewart
    Pathology 37:258-61. 2005
  45. ncbi Ovarian mucinous tumour with multifocal endocrine cell micronests
    Colin J R Stewart
    Pathology 40:91-3. 2008