David J Speers

Summary

Affiliation: Western Australia
Country: Australia

Publications

  1. pmc Clinical and radiological predictors of outcome for Murray Valley encephalitis
    David J Speers
    Department of Microbiology, PathWest Laboratory Medicine WA, Nedlands, Western Australia, Australia
    Am J Trop Med Hyg 88:481-9. 2013
  2. ncbi request reprint Diagnosis of malaria aided by polymerase chain reaction in two cases with low-level parasitaemia
    D J Speers
    Department of General Medicine, Sir Charles Gairdner Hospital, The Western Australian Centre for Pathology and Medical Research, Perth, Western Australia 6009, Australia
    Intern Med J 33:613-5. 2003
  3. pmc Combination assay detecting both human immunodeficiency virus (HIV) p24 antigen and anti-HIV antibodies opens a second diagnostic window
    David Speers
    Division of Clinical Microbiology and Infectious Diseases, The Western Australian Centre for Pathology and Medical Research PathCentre, Hospital Avenue, Nedlands, Western Australia 6009, Australia
    J Clin Microbiol 43:5397-9. 2005
  4. ncbi request reprint Oseltamivir-resistant pandemic (H1N1) 2009 influenza in a severely ill patient: the first Australian case
    David J Speers
    Division of Microbiology and Infectious Diseases, PathWest Laboratory Medicine WA, Perth, WA
    Med J Aust 192:166-8. 2010
  5. doi request reprint The detection of oseltamivir-resistant pandemic influenza A/H1N1 2009 viruses using a real-time RT-PCR assay
    Glenys R Chidlow
    Department of Microbiology, PathWest Laboratory Medicine WA, Nedlands, Australia
    J Virol Methods 169:47-51. 2010
  6. ncbi request reprint Penicillin-resistant Neisseria meningitidis bacteraemia, Kimberley region, March 2010
    Shivanti D Abeysuriya
    Department of Microbiology, PathWest Laboratory Medicine, Queen Elizabeth II Medical Centre, Nedlands, Western Australia
    Commun Dis Intell Q Rep 34:342-4. 2010
  7. ncbi request reprint Validation of the FibroTest biochemical markers score in assessing liver fibrosis in hepatitis C patients
    Enrico Rossi
    Clinical Biochemistry, PathCentre, Nedlands, Western Australia, Australia
    Clin Chem 49:450-4. 2003
  8. pmc Duplex real-time reverse transcriptase PCR assays for rapid detection and identification of pandemic (H1N1) 2009 and seasonal influenza A/H1, A/H3, and B viruses
    Glenys Chidlow
    Department of Microbiology, PathWest Laboratory Medicine WA, QEII Medical Centre, Nedlands, Western Australia, Australia
    J Clin Microbiol 48:862-6. 2010
  9. doi request reprint Procalcitonin and C-reactive protein in severe 2009 H1N1 influenza infection
    Paul Robert Ingram
    Microbiology and Infectious Diseases, PathWest Laboratories, Hospital Ave, Nedlands, Perth, WA 6160, Australia
    Intensive Care Med 36:528-32. 2010
  10. ncbi request reprint Influenza and respiratory syncytial virus are the major respiratory viruses detected from prospective testing of pediatric and adult coronial autopsies
    David J Speers
    Department of Microbiology, PathWest Laboratory Medicine WA, Queen Elizabeth II Medical Centre, Nedlands, WA, Australia School of Medicine and Pharmacology, University of Western Australia, Crawley, WA, Australia
    Influenza Other Respir Viruses 7:1113-21. 2013

Collaborators

Detail Information

Publications16

  1. pmc Clinical and radiological predictors of outcome for Murray Valley encephalitis
    David J Speers
    Department of Microbiology, PathWest Laboratory Medicine WA, Nedlands, Western Australia, Australia
    Am J Trop Med Hyg 88:481-9. 2013
    ..MRI scans repeated months after acute illness showed destruction of the thalamus and basal ganglia, cortex, or cerebellum. These findings may help clinicians predict the neurological outcome when evaluating patients with MVE...
  2. ncbi request reprint Diagnosis of malaria aided by polymerase chain reaction in two cases with low-level parasitaemia
    D J Speers
    Department of General Medicine, Sir Charles Gairdner Hospital, The Western Australian Centre for Pathology and Medical Research, Perth, Western Australia 6009, Australia
    Intern Med J 33:613-5. 2003
    ..Plasmodium vivax was detected by PCR prior to the light microscopy becoming positive in one case, and in the second case Plasmodium malariae was detected when light microscopy was unable to speciate the causative Plasmodium species...
  3. pmc Combination assay detecting both human immunodeficiency virus (HIV) p24 antigen and anti-HIV antibodies opens a second diagnostic window
    David Speers
    Division of Clinical Microbiology and Infectious Diseases, The Western Australian Centre for Pathology and Medical Research PathCentre, Hospital Avenue, Nedlands, Western Australia 6009, Australia
    J Clin Microbiol 43:5397-9. 2005
    ..Although it is likely to be rare, this phenomenon has also been reported for other fourth-generation HIV immunoassays and has implications for the reported diagnostic windows of these assays...
  4. ncbi request reprint Oseltamivir-resistant pandemic (H1N1) 2009 influenza in a severely ill patient: the first Australian case
    David J Speers
    Division of Microbiology and Infectious Diseases, PathWest Laboratory Medicine WA, Perth, WA
    Med J Aust 192:166-8. 2010
    ..He subsequently died of non-respiratory complications. This is the first case of oseltamivir-resistant pandemic (H1N1) 2009 in Australia and the first report of resistance in a solid organ transplant recipient...
  5. doi request reprint The detection of oseltamivir-resistant pandemic influenza A/H1N1 2009 viruses using a real-time RT-PCR assay
    Glenys R Chidlow
    Department of Microbiology, PathWest Laboratory Medicine WA, Nedlands, Australia
    J Virol Methods 169:47-51. 2010
    ..The sensitive rRT-PCR assays may be performed directly on patient specimens, can detect resistant virus at low levels, and therefore may provide early warning of developing resistance within individual patients or the wider population...
  6. ncbi request reprint Penicillin-resistant Neisseria meningitidis bacteraemia, Kimberley region, March 2010
    Shivanti D Abeysuriya
    Department of Microbiology, PathWest Laboratory Medicine, Queen Elizabeth II Medical Centre, Nedlands, Western Australia
    Commun Dis Intell Q Rep 34:342-4. 2010
    ..meningitidis disease is of concern and emphasises the importance of ongoing surveillance for antimicrobial resistance...
  7. ncbi request reprint Validation of the FibroTest biochemical markers score in assessing liver fibrosis in hepatitis C patients
    Enrico Rossi
    Clinical Biochemistry, PathCentre, Nedlands, Western Australia, Australia
    Clin Chem 49:450-4. 2003
    ..We investigated the predictive value of the proprietary FibroTest score to accurately identify significant fibrosis in Australian hepatitis C patients...
  8. pmc Duplex real-time reverse transcriptase PCR assays for rapid detection and identification of pandemic (H1N1) 2009 and seasonal influenza A/H1, A/H3, and B viruses
    Glenys Chidlow
    Department of Microbiology, PathWest Laboratory Medicine WA, QEII Medical Centre, Nedlands, Western Australia, Australia
    J Clin Microbiol 48:862-6. 2010
    ..9% for seasonal A/H1, and 96.3% and 99.6% for A/H3. Automated sample extraction facilitated the rapid processing of samples so that the assays allowed accurate, rapid, and cost-effective screening of large numbers of clinical samples...
  9. doi request reprint Procalcitonin and C-reactive protein in severe 2009 H1N1 influenza infection
    Paul Robert Ingram
    Microbiology and Infectious Diseases, PathWest Laboratories, Hospital Ave, Nedlands, Perth, WA 6160, Australia
    Intensive Care Med 36:528-32. 2010
    ..To examine whether, in an adult intensive care unit (ICU), procalcitonin or C-reactive protein (CRP) levels discriminated between 2009 H1N1 influenza infection and community-acquired pneumonia of bacterial origin...
  10. ncbi request reprint Influenza and respiratory syncytial virus are the major respiratory viruses detected from prospective testing of pediatric and adult coronial autopsies
    David J Speers
    Department of Microbiology, PathWest Laboratory Medicine WA, Queen Elizabeth II Medical Centre, Nedlands, WA, Australia School of Medicine and Pharmacology, University of Western Australia, Crawley, WA, Australia
    Influenza Other Respir Viruses 7:1113-21. 2013
    ..To ascertain the full mortality of influenza and other respiratory viruses, the testing of community autopsy specimens is essential...
  11. pmc Real-time PCR assay for detection of blaZ genes in Staphylococcus aureus clinical isolates
    Lynette A Pereira
    Department of Microbiology, PathWest Laboratory Medicine WA, Queen Elizabeth II Medical Centre, Nedlands, Western Australia, Australia
    J Clin Microbiol 52:1259-61. 2014
    ..Conventional PCR methods have demonstrated superior sensitivity and specificity to phenotypic tests. To our knowledge, this is the first description of real-time PCR detection of the blaZ gene. ..
  12. doi request reprint The viruses of Australia and the risk to tourists
    David W Smith
    PathWest Laboratory Medicine WA, Queen Elizabeth II Medical Centre, Nedlands, Western Australia 6909, Australia
    Travel Med Infect Dis 9:113-25. 2011
    ..However, it is important to remember that most tourists pass through other countries in the Asia/Pacific region on their way to and from Australia and may therefore have acquired infections prior to or after leaving Australia...
  13. doi request reprint Decline in native kidney function in liver transplant recipients is not associated with BK virus infection
    Muna Salama
    Department of Gastroenterology Hepatology, University of Western Australia, Perth, Australia
    Liver Transpl 14:1787-92. 2008
    ..It appears that the most probable pathway for the development of BKV nephropathy requires a second hit, such as kidney inflammation, kidney ischemia, or donor-recipient human leukocyte antigen mismatch...
  14. ncbi request reprint Hepascore: an accurate validated predictor of liver fibrosis in chronic hepatitis C infection
    Leon A Adams
    Department of Gastroenterology and Hepatology, Sir Charles Gairdner Hospital, Perth, Australia
    Clin Chem 51:1867-73. 2005
    ..We sought to create an algorithm of serum markers that accurately and reliably predict liver fibrosis stage among hepatitis C patients...
  15. pmc Outbreak of sporotrichosis, Western Australia
    Kynan T Feeney
    Sir Charles Gairdner Hospital, Nedlands, Western Australia, Australia
    Emerg Infect Dis 13:1228-31. 2007
    ..Declining infection rates have occurred after various community measures were instigated...
  16. ncbi request reprint Does sequencing the PKRBD of hepatitis C virus NS5A predict therapeutic response to combination therapy in an Australian population?
    Gerry C MacQuillan
    Department of Medicine, University of Western Australia, Crawley, Western Australia, Australia
    J Gastroenterol Hepatol 19:551-7. 2004
    ..Patients infected with a HCV genotype 1 prototype sequence should be counseled before receiving combination IFN-alpha and ribavirin therapy as they have a poor response to treatment...