Research Topics
| T J InglisSummaryAffiliation: Western Australia Country: Australia Publications
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Detail Information
Publications
Expanded range of Burkholderia species in AustraliaAvram Levy
Division of Microbiology and Infectious Diseases, PathWest Laboratory Medicine, Perth, Australia
Am J Trop Med Hyg 78:599-604. 2008..Evidence of these species in Australia has implications for bacterial identification in clinical laboratories, diagnostic serology tests, and environmental biodiversity studies...
Use of matrix-assisted laser desorption/ionization time-of-flight mass spectrometry analysis for rapid confirmation of Burkholderia pseudomallei in septicemic melioidosisTimothy J J Inglis
School of Pathology and Laboratory Medicine, Faculty of Medicine, Dentistry, and Health Sciences, University of Western Australia, Nedlands 6009, Western Australia, Australia
Am J Trop Med Hyg 86:1039-42. 2012..This procedure reduced the time to definitive identification by more than 24 hours. This analysis is a useful addition to laboratory methods for early recognition of septicemic melioidosis in non-endemic settings...
Burkholderia pseudomallei traced to water treatment plant in AustraliaT J Inglis
Western Australian Centre for Pathology and Medical Research, Nedlands, Australia
Emerg Infect Dis 6:56-9. 2000..B. pseudomallei was isolated from a water storage tank and from spray formed in a pH-raising aerator unit. Pulsed-field gel electrophoresis confirmed the aerator and storage tank isolates were identical to the outbreak strain, WKo97...
Melioidosis in the AmericasTimothy J J Inglis
Division of Microbiology and Infectious Diseases, PathWest Laboratory Medicine Western Australia, Queen Elizabeth II Medical Centre, Nedlands, Western Australia, Australia
Am J Trop Med Hyg 75:947-54. 2006..Increased clinical awareness of the disease and improvements in laboratory diagnostic methods are likely to bring wider recognition of melioidosis in the Americas...
Principia aetiologica: taking causality beyond Koch's postulatesTimothy J J Inglis
Division of Microbiology and Infectious Diseases, PathWest Laboratory Medicine WA, QEII Medical Centre, University of Western Australia, Nedlands, WA 6909, Australia
J Med Microbiol 56:1419-22. 2007..A priobe is the sufficient and necessary antecedent cause of a pathophysiological process evident as an infectious disease...
Deployable laboratory response to emergence of melioidosis in central Sri LankaTimothy J J Inglis
Division of Microbiology and Infectious Diseases, PathWest Laboratory Medicine WA, QEII Medical Centre, Hospital Avenue, Nedlands, Locked Bag 2009, Western Australia 6909, Australia
J Clin Microbiol 46:3479-81. 2008..Soil supernatants from rice field and rubber plantation samples also produced PCR-positive results. These procedures could be used for melioidosis field work in other remote locations...
Melioidosis risk in a tropical industrial environmentTimothy J J Inglis
Division of Microbiology and Infectious Diseases, PathWest Laboratory Medicine, Westerm Australia, Australia
Am J Trop Med Hyg 80:78-84. 2009..The effect of long-term climatic trends on this potential biologic threat requires further study...
Trouble in paradiseTimothy J J Inglis
Division of Microbiology and Infectious Diseases, PathWest Laboratory Medicine WA, Perth, WA, Australia
Med J Aust 191:597-8. 2009..Conference delegates workshopped a realistically staged disaster scenario in which they were completely isolated from outside resources...
Emergence of multi-resistant Pseudomonas aeruginosa in a Western Australian hospitalT J J Inglis
PathWest Laboratory Medicine WA, Perth, WA, Australia
J Hosp Infect 76:60-5. 2010..The third seasonal cluster persisted for longer, indicating adaption to environment. More effective environmental control of P. aeruginosa is urgently needed...
The aftermath of the Western Australian melioidosis outbreakTimothy J J Inglis
Division of Microbiology and Infectious Diseases, PathWest Laboratory Medicine, Nedlands, WA 6009, Australia
Am J Trop Med Hyg 84:851-7. 2011..Additional biogeographic and ecological studies are needed to establish the relative importance of environmental cofactors in disease pathogenesis...
Deployable laboratory response to influenza pandemic; PCR assay field trials and comparison with reference methodsTimothy J J Inglis
Division of Microbiology and Infectious Diseases, PathWest Laboratory Medicine WA, QEII Medical Centre, Nedlands, Western Australia, Australia
PLoS ONE 6:e25526. 2011..Influenza A/H1N1/09 became the dominant seasonal variant and returned to Australia during the Southern winter the following year...
Multiresistant Escherichia coli in aged care: the gathering stormTimothy J J Inglis
Division of Microbiology and Infectious Diseases, PathWest Laboratory Medicine WA, Perth, WA, Australia
Med J Aust 195:489-90. 2011..The growing infection control challenges facing an ageing population...
Clinical guideline for diagnosis and management of melioidosisTimothy J J Inglis
Division of Microbiology and Infectious Diseases, QEII Medical Centre, Nedlands, WA, Australia
Rev Inst Med Trop Sao Paulo 48:1-4. 2006....
Comparison of diagnostic laboratory methods for identification of Burkholderia pseudomalleiTimothy J J Inglis
Division of Microbiology and Infectious Diseases, Western Australian Centre for Pathology and Medical Research PathCentre, Locked Bag 2009, Nedlands, WA 6009, Australia
J Clin Microbiol 43:2201-6. 2005..Incorporation of PCR-based identification within this schema may improve percentages of recognition further but requires more detailed evaluation...
Comparison of rapid, automated ribotyping and DNA macrorestriction analysis of Burkholderia pseudomalleiTimothy J J Inglis
Division of Microbiology and Infectious Diseases, Western Australian Centre for Pathology, Nedlands, Australia
J Clin Microbiol 40:3198-203. 2002..pseudomallei as a biohazard...
Preliminary report on the northern Australian melioidosis environmental surveillance projectT J J Inglis
Western Australian Centre for Pathology and Medical Research PathCentre, Locked Bag 2009, Nedlands, WA 6909, Australia
Epidemiol Infect 132:813-20. 2004..that are potential hosts to B. pseudomallei were recovered from environmental specimens. Culturable B. pseudomallei was not found to be widely dispersed in the environments sampled...
Flagellum-mediated adhesion by Burkholderia pseudomallei precedes invasion of Acanthamoeba astronyxisTimothy J J Inglis
Department of Microbiology, Faculty of Medicine and Dentistry, University of Western Australia, Western Australian Centre for Pathology and Medical Research, Nedlands, WA 6909, Australia
Infect Immun 71:2280-2. 2003..pseudomallei NCTC 1026b did not demonstrate flagellum-mediated endocytosis in timed coculture, confirming that an intact flagellar apparatus assists B. pseudomallei entry into A. astronyxis...
Comparison of the susceptibilities of Burkholderia pseudomallei to meropenem and ceftazidime by conventional and intracellular methodsT J J Inglis
The Division of Microbiology and Infectious Diseases, Western Australian Centre for Pathology and Medical Research, Nedlands, Western Australia, Australia
Antimicrob Agents Chemother 48:2999-3005. 2004..Further development of the intracellular MIC method is expected to help assess the efficacy of antimicrobial agents on this bacterial species in an intracellular setting...
Cellular fatty acid profile distinguishes Burkholderia pseudomallei from avirulent Burkholderia thailandensisTimothy J J Inglis
Division of Microbiology and Infectious Diseases, Western Australian Centre for Pathology and Medical Research, Nedlands, Western Australia, Australia
J Clin Microbiol 41:4812-4. 2003..thailandensis isolates. GC mass spectrophotometry confirmed that 2-hydroxymyristic acid was present in B. pseudomallei. GC-fatty acid methyl ester analysis may be useful in distinguishing these two closely related species...
Interaction between Burkholderia pseudomallei and Acanthamoeba species results in coiling phagocytosis, endamebic bacterial survival, and escapeT J Inglis
Division of Microbiology, Western Australian Centre for Pathology and Medical Research, Nedlands, Western Australia 6009
Infect Immun 68:1681-6. 2000..pseudomallei and subsequent human exposure. Endamebic passage of B. pseudomallei warrants further investigation as a potential in vitro model of intracellular B. pseudomallei infection...
Case report: recovery from persistent septicemic melioidosisT J Inglis
Division of Microbiology and Infectious Diseases, Western Australian Centre for Pathology and Medical Research, Nedlands, Australia
Am J Trop Med Hyg 65:76-82. 2001..A combination of antibiotics known to possess intracellular activity against B. pseudomallei, surgery and supportive critical care may provide a means of improving the probability of survival in persistent septicemic melioidosis...
A hospital-wide study of the impact of introducing a personal data assistant-augmented blood culture roundTimothy J J Inglis
1Division of Microbiology and Infectious Diseases, PathWest Laboratory Medicine WA, QEII Medical Centre, Nedlands, WA 6909, Australia
J Med Microbiol 57:43-9. 2008..Introduction of molecular identification tests, such as multiplex PCR methods, at the Gram-stain stage of blood culture is unlikely to affect the rate of death in hospital, but may reduce the length of hospital admission...
Molecular epidemiology of Scedosporium apiospermum infection determined by PCR amplification of ribosomal intergenic spacer sequences in patients with chronic lung diseaseE C Williamson
Division of Microbiology and Infectious Diseases, The Western Australian Center for Pathology and Medical Research PathCentre, Nedlands 6009, Australia
J Clin Microbiol 39:47-50. 2001..There was no epidemiological evidence of direct patient-to-patient spread, and Scedosporium organisms were not isolated from dust, soil, or air samples from the unit. The source and route of transmission have yet to be determined...
PCR-based identification of Burkholderia pseudomalleiAdam Merritt
Division of Microbiology and Infectious Diseases, PathWest Laboratory Medicine WA, QEII Medical Centre, Nedlands, Australia
Rev Inst Med Trop Sao Paulo 48:239-44. 2006....
Disinfection of Burkholderia pseudomallei in potable waterKay Howard
Division of Microbiology and Infectious Diseases, Western Australian Centre for Pathology and Medical Research, Locked Bag 2009, Nedlands WA 6909, Australia
Water Res 39:1085-92. 2005..Given the results obtained from these co-culture experiments, more research is needed to investigate the role of amoeba and biofilms in survival of B. pseudomallei in potable water...
The public health implications of melioidosisTimothy J J Inglis
University of Western Australia, Australia
Braz J Infect Dis 13:59-66. 2009..Climate change-driven extreme weather events will both increase the prevalence of infection and gradually extend its main endemic zone...
Environmental factors that affect the survival and persistence of Burkholderia pseudomalleiTimothy J J Inglis
Division of Microbiology and Infectious Diseases, PathWest Laboratory Medicine WA, Hospital Avenue, QEII Medical Centre, Nedlands, Western Australia 6909, Australia
Appl Environ Microbiol 72:6865-75. 2006
Invasion of spores of the arbuscular mycorrhizal fungus Gigaspora decipiens by Burkholderia sppAvram Levy
School of Biomedical and Chemical Sciences, The University of Western Australia, Queen Elizabeth II Medical Centre, Nedlands, Australia
Appl Environ Microbiol 69:6250-6. 2003..Burkholderia spp. colonized both hyphae and spores, attaching to surfaces in either an end-on or side-on fashion. Adherence of Burkholderia spp. to eukaryotic surfaces also involved the formation of numerous fibrillar structures...
The effect of free chlorine on Burkholderia pseudomallei in potable waterKay Howard
Division of Microbiology and Infectious Diseases, Western Australian Centre for Pathology and Medical Research, Locked Bag 2009, WA 6909, Nedlands, Australia
Water Res 37:4425-32. 2003..This finding has practical implications for water treatment in regions where B. pseudomallei is endemic. Future work to assess the effect of alternative water disinfection processes either singly or in sequence is necessary...
Melioidosis, northeastern BrazilDionne Bezerra Rolim
, Cear, Brazil
Emerg Infect Dis 11:1458-60. 2005....
