Peter R Eastwood

Summary

Affiliation: Western Australia
Country: Australia

Publications

  1. doi request reprint How to write research papers and grants: 2011 Asian Pacific Society for Respirology Annual Scientific Meeting Postgraduate Session
    Peter R Eastwood
    West Australian Sleep Disorders Research Institute, Department of Pulmonary Physiology and Sleep Medicine, Sir Charles Gairdner Hospital, Perth, Western Australia, Australia
    Respirology 17:792-801. 2012
  2. ncbi request reprint Collapsibility of the upper airway at different concentrations of propofol anesthesia
    Peter R Eastwood
    West Australian Sleep Disorders Research Institute, Department of Pulmonary Physiology, Sir Charles Gairdner Hospital, and School of Anatomy and Human Biology, University of Western Australia
    Anesthesiology 103:470-7. 2005
  3. ncbi request reprint Modulation of upper and lower esophageal sphincter tone during sleep
    Peter R Eastwood
    Department of Pulmonary Physiology, Sir Charles Gairdner Hospital, Hospital Avenue, Nedlands, WA 6009, Australia
    Sleep Med 8:135-43. 2007
  4. ncbi request reprint High-intensity inspiratory muscle training in COPD
    K Hill
    Dept of Pulmonary Physiology, Sir Charles Gairdner Hospital, Hospital Avenue, Nedlands, Western Australia, 6009 Australia
    Eur Respir J 27:1119-28. 2006
  5. ncbi request reprint Anaerobic metabolism of inspiratory muscles in COPD
    Peter R Eastwood
    Department of Pulmonary Physiology, Sir Charles Gairdner Hospital, Perth, Western Australia, Australia
    Respirology 11:32-40. 2006
  6. doi request reprint Obstructive Sleep Apnoea: From pathogenesis to treatment: Current controversies and future directions
    Peter R Eastwood
    West Australian Sleep Disorders Research Institute, Department of Pulmonary Physiology, Sir Charles Gairdner Hospital, Nedlands, WA 6009, Australia
    Respirology 15:587-95. 2010
  7. pmc Treating obstructive sleep apnea with hypoglossal nerve stimulation
    Peter R Eastwood
    Sir Charles Gairdner Hospital, Perth, Australia
    Sleep 34:1479-86. 2011
  8. doi request reprint Evaluation of pharyngeal shape and size using anatomical optical coherence tomography in individuals with and without obstructive sleep apnoea
    Jennifer H Walsh
    West Australian Sleep Disorders Research Institute, Sir Charles Gairdner Hospital, Perth, Western Australia, Australia
    J Sleep Res 17:230-8. 2008
  9. pmc Effect of body posture on pharyngeal shape and size in adults with and without obstructive sleep apnea
    Jennifer H Walsh
    West Australian Sleep Disorders Research Institute, Sir Charles Gairdner Hospital, Nedlands, Western Australia
    Sleep 31:1543-9. 2008
  10. pmc Influence of head extension, flexion, and rotation on collapsibility of the passive upper airway
    Jennifer H Walsh
    West Australian Sleep Disorders Research Institute, Department of Pulmonary Physiology, Sir Charles Gairdner Hospital, Nedlands, WA, Australia
    Sleep 31:1440-7. 2008

Detail Information

Publications50

  1. doi request reprint How to write research papers and grants: 2011 Asian Pacific Society for Respirology Annual Scientific Meeting Postgraduate Session
    Peter R Eastwood
    West Australian Sleep Disorders Research Institute, Department of Pulmonary Physiology and Sleep Medicine, Sir Charles Gairdner Hospital, Perth, Western Australia, Australia
    Respirology 17:792-801. 2012
    ....
  2. ncbi request reprint Collapsibility of the upper airway at different concentrations of propofol anesthesia
    Peter R Eastwood
    West Australian Sleep Disorders Research Institute, Department of Pulmonary Physiology, Sir Charles Gairdner Hospital, and School of Anatomy and Human Biology, University of Western Australia
    Anesthesiology 103:470-7. 2005
    ..This study investigated the effect of varying concentrations of propofol on upper airway collapsibility and the mechanisms responsible for it...
  3. ncbi request reprint Modulation of upper and lower esophageal sphincter tone during sleep
    Peter R Eastwood
    Department of Pulmonary Physiology, Sir Charles Gairdner Hospital, Hospital Avenue, Nedlands, WA 6009, Australia
    Sleep Med 8:135-43. 2007
    ..This study sought to describe the effects of sleep, respiration and posture on the function of the UES and the LES and the pressure differentials developed across them...
  4. ncbi request reprint High-intensity inspiratory muscle training in COPD
    K Hill
    Dept of Pulmonary Physiology, Sir Charles Gairdner Hospital, Hospital Avenue, Nedlands, Western Australia, 6009 Australia
    Eur Respir J 27:1119-28. 2006
    ..In conclusion, high-intensity inspiratory muscle training improves inspiratory muscle function in subjects with moderate-to-severe chronic obstructive pulmonary disease, yielding meaningful reductions in dyspnoea and fatigue...
  5. ncbi request reprint Anaerobic metabolism of inspiratory muscles in COPD
    Peter R Eastwood
    Department of Pulmonary Physiology, Sir Charles Gairdner Hospital, Perth, Western Australia, Australia
    Respirology 11:32-40. 2006
    ....
  6. doi request reprint Obstructive Sleep Apnoea: From pathogenesis to treatment: Current controversies and future directions
    Peter R Eastwood
    West Australian Sleep Disorders Research Institute, Department of Pulmonary Physiology, Sir Charles Gairdner Hospital, Nedlands, WA 6009, Australia
    Respirology 15:587-95. 2010
    ....
  7. pmc Treating obstructive sleep apnea with hypoglossal nerve stimulation
    Peter R Eastwood
    Sir Charles Gairdner Hospital, Perth, Australia
    Sleep 34:1479-86. 2011
    ..Reduced upper airway muscle activity during sleep is fundamental to obstructive sleep apnea (OSA) pathogenesis. Hypoglossal nerve stimulation (HGNS) counteracts this problem, with potential to reduce OSA severity...
  8. doi request reprint Evaluation of pharyngeal shape and size using anatomical optical coherence tomography in individuals with and without obstructive sleep apnoea
    Jennifer H Walsh
    West Australian Sleep Disorders Research Institute, Sir Charles Gairdner Hospital, Perth, Western Australia, Australia
    J Sleep Res 17:230-8. 2008
    ..These findings suggest that it is an abnormality in size rather than shape that is the more important anatomical predictor of OSA...
  9. pmc Effect of body posture on pharyngeal shape and size in adults with and without obstructive sleep apnea
    Jennifer H Walsh
    West Australian Sleep Disorders Research Institute, Sir Charles Gairdner Hospital, Nedlands, Western Australia
    Sleep 31:1543-9. 2008
    ..This study compared the effect of body posture on upper airway shape and size in individuals with OSA with control subjects matched for age, BMI, and gender...
  10. pmc Influence of head extension, flexion, and rotation on collapsibility of the passive upper airway
    Jennifer H Walsh
    West Australian Sleep Disorders Research Institute, Department of Pulmonary Physiology, Sir Charles Gairdner Hospital, Nedlands, WA, Australia
    Sleep 31:1440-7. 2008
    ..To determine the effect of head posture on upper airway collapsibility and site of collapse of the passive human upper airway...
  11. ncbi request reprint Applying anatomical optical coherence tomography to quantitative 3D imaging of the lower airway
    Robert A McLaughlin
    Optical Biomedical Engineering Laboratory, School of Electrical, Electronic and Computer Engineering, University of Western Australia, Crawley, WA 6009, Australia
    Opt Express 16:17521-9. 2008
    ..The paper also illustrates the capability of the system to assess the real-time dynamic changes within the airway that occur during respiration...
  12. ncbi request reprint Relationship between upper airway and inspiratory pump muscle force in obstructive sleep apnea
    Kelly L Shepherd
    West Australian Sleep Disorders Research Institute, Department of Pulmonary Physiology, Sir Charles Gairdner Hospital, Nedlands, Western Australia 6009, Australia
    Chest 130:1757-64. 2006
    ..It is possible that the relative strengths of UA dilator and inspiratory pump muscles could be an important determinant of the susceptibility to UA collapse during sleep (ie, obstructive sleep apnea [OSA])...
  13. doi request reprint Estimating maximum work rate during incremental cycle ergometry testing from six-minute walk distance in patients with chronic obstructive pulmonary disease
    Kylie Hill
    Department of Pulmonary Physiology, Sir Charles Gairdner Hospital, Nedlands, Western Australia, Australia
    Arch Phys Med Rehabil 89:1782-7. 2008
    ....
  14. doi request reprint Gastro-oesophageal reflux symptoms are related to the presence and severity of obstructive sleep apnoea
    Kelly L Shepherd
    Department of Pulmonary Physiology, West Australian Sleep Disorders Research Institute, Sir Charles Gairdner Hospital, Nedlands, Australia
    J Sleep Res 20:241-9. 2011
    ..This association is independent of other risk factors including age, gender and body mass index, suggesting a causal relationship between OSA and nocturnal reflux...
  15. doi request reprint Evolution of changes in upper airway collapsibility during slow induction of anesthesia with propofol
    David R Hillman
    West Australian Sleep Disorders Research Institute, and Department of Pulmonary Physiology, Sir Charles Gairdner Hospital, Nedlands, Western Australia, Australia 6009
    Anesthesiology 111:63-71. 2009
    ..This study assessed how this increase in collapsibility evolves during slow Propofol induction and how it relates to anesthesia-induced changes in upper airway muscle activity and conscious state...
  16. ncbi request reprint Feasibility of Applying Real-time Optical Imaging During Bronchoscopic Interventions for Central Airway Obstruction
    Jonathan P Williamson
    Departments of Pulmonary Physiology Respiratory Medicine Radiology, Sir Charles Gairdner Hospital School of Anatomy and Human Biology Optical Biomedical Engineering Laboratory, School of Electrical, Electronic and Computer Engineering, The University of Western Australia West Australian Sleep Disorders Research Institute, Perth, Australia
    J Bronchology Interv Pulmonol 17:307-16. 2010
    ..This study aims to describe the potential role of real-time aOCT in guiding interventions during CAO procedures...
  17. doi request reprint Variability of human upper airway collapsibility during sleep and the influence of body posture and sleep stage
    Jeremy S L Ong
    Centre for Sleep Science, School of Anatomy and Human Biology, University of Western Australia, Australia
    J Sleep Res 20:533-7. 2011
    ..When within-subject variability is accounted for, change in body posture from supine to lateral significantly decreases passive pharyngeal collapsibility...
  18. ncbi request reprint Respiratory gating of anatomical optical coherence tomography images of the human airway
    Robert A McLaughlin
    Optical Biomedical Engineering Laboratory, School of Electrical, Electronic and Computer Engineering, University of Western Australia, Crawley WA 6009, Australia
    Opt Express 17:6568-77. 2009
    ..It is shown that respiratory gating can substantially improve the quality of aOCT images and reveal events and features that are otherwise obscured by blurring...
  19. ncbi request reprint Physiologic responses to incremental and self-paced exercise in COPD: a comparison of three tests
    Sian E Turner
    Physiotherapy Department, Sir Charles Gairdner Hospital, Hospital Avenue, Nedlands, WA, Australia
    Chest 126:766-73. 2004
    ..To investigate cardiorespiratory and dyspnea responses to incremental and self-paced exercise tests in patients with COPD...
  20. doi request reprint Elastic properties of the central airways in obstructive lung diseases measured using anatomical optical coherence tomography
    Jonathan P Williamson
    Department of Pulmonary Physiology, Sir Charles Gairdner Hospital, Perth, Australia
    Am J Respir Crit Care Med 183:612-9. 2011
    ..Such knowledge could help elucidate mechanisms of excessive airway narrowing...
  21. ncbi request reprint Dyspnoea in COPD: can inspiratory muscle training help?
    Kylie Hill
    Department of Pulmonary Physiology, Sir Charles Gairdner Hospital, Nedlands, WA 6009, Australia
    Aust J Physiother 50:169-80. 2004
    ..This paper describes the origin of dyspnoea in COPD, with particular attention given to the role of inspiratory muscle dysfunction in its genesis and its possible amelioration through inspiratory muscle training...
  22. pmc Distribution of airway narrowing responses across generations and at branching points, assessed in vitro by anatomical optical coherence tomography
    Peter B Noble
    Division of Clinical Sciences, Telethon Institute for Child Health Research, Roberts Road, Perth, 6008, Australia
    Respir Res 11:9. 2010
    ..Whilst heterogeneity has been detected by previous experimental approaches, its spatial relationship either within or between airways is unknown...
  23. doi request reprint Inspiratory muscle training for patients with chronic obstructive pulmonary disease: a practical guide for clinicians
    Kylie Hill
    Curtin Health Innovation Research Institute, Curtin University, Perth, Australia
    Arch Phys Med Rehabil 91:1466-70. 2010
    ..It is prudent to exclude people at risk of pneumothorax or spontaneous rib fracture. Evaluation of IMT should include measures of PImax, dyspnea, health-related quality of life, and exercise capacity...
  24. ncbi request reprint The effect of learning on ventilatory responses to inspiratory threshold loading in COPD
    Gavin A Sturdy
    Department of Pulmonary Physiology, Sir Charles Gairdner Hospital, Nedlands, WA 6009, Australia
    Respir Med 98:1-8. 2004
    ..This study sought to determine whether a similar "learning effect" is evident in patients with COPD, and what the mechanism of any such effect may be...
  25. doi request reprint Anesthesia, sleep, and upper airway collapsibility
    David R Hillman
    West Australian Sleep Disorders Research Institute, Department of Pulmonary Physiology, Sir Charles Gairdner Hospital, Nedlands, Perth, Australia
    Anesthesiol Clin 28:443-55. 2010
    ..Specific follow-up of suspected cases is needed to ensure that the sleep-related component of the problem receives appropriate care...
  26. ncbi request reprint Obstructive sleep apnoea and anaesthesia
    David R Hillman
    West Australian Sleep Disorders Research Institute and Department of Pulmonary Physiology, Sir Charles Gairdner Hospital, Perth, WA, Australia
    Sleep Med Rev 8:459-71. 2004
    ..On the other hand difficulty with airway maintenance during anaesthesia should prompt further investigation for the possibility of OSA...
  27. ncbi request reprint Six-minute walk distance in healthy Singaporean adults cannot be predicted using reference equations derived from Caucasian populations
    Hermione Poh
    School of Physiotherapy, Curtin University of Technology, Perth, Western Australia, Australia
    Respirology 11:211-6. 2006
    ..The aim of this study was to determine 6MWD in healthy Singaporeans and identify contributors to 6MWD in this population. We also compared measured 6MWD with predicted 6MWD from two regression equations derived in Caucasian subjects...
  28. doi request reprint The effect of diaphragm contraction on upper airway collapsibility
    David R Hillman
    West Australian Sleep Disorders Research Institute, Department of Pulmonary Physiology and Sleep Medicine, Sir Charles Gairdner Hospital, Perth, Australia
    J Appl Physiol 115:337-45. 2013
    ..The effect appears primarily mediated by changes in lung volume rather than mediastinal traction from diaphragm descent. The study provides a rationale for use of continuous phrenic stimulation to treat obstructive sleep apnea. ..
  29. doi request reprint Obstructive sleep apnoea and nocturnal gastroesophageal reflux are common in lung transplant patients
    Kelly L Shepherd
    Department of Pulmonary Physiology, West Australian Sleep Disorders Research Institute, Sir Charles Gairdner Hospital, Nedlands, WA, Australia
    Respirology 13:1045-52. 2008
    ..This study investigated the relationship between nocturnal GOR, OSA and BOS in a group of lung transplant patients...
  30. doi request reprint Using optical coherence tomography to improve diagnostic and therapeutic bronchoscopy
    Jonathan P Williamson
    Department of Pulmonary Physiology, Sir Charles Gairdner Hospital, Nedlands, Perth, WA 6009, Australia
    Chest 136:272-6. 2009
    ..The severity of newly diagnosed tracheomalacia was able to be quantified using aOCT imaging (subject 3). aOCT imaging during bronchoscopy allows accurate real-time airway measurements and may assist bronchoscopic assessment...
  31. ncbi request reprint Heterogeneous activity of the human genioglossus muscle assessed by multiple bipolar fine-wire electrodes
    Peter R Eastwood
    Department of Pulmonary Physiology, Sir Charles Gairdner Hospital, University of Western Australia, Australia 6009
    J Appl Physiol 94:1849-58. 2003
    ..We hypothesize that regional differences in density and type of muscle fiber are the most likely sources of heterogeneity in these responses...
  32. ncbi request reprint Collapsibility of the upper airway during anesthesia with isoflurane
    Peter R Eastwood
    West Australian Sleep Disorders Research Institute, Department of Pulmonary Physiology, Sir Charles Gairdner Hospital, Nedlands, Western Australia, Australia
    Anesthesiology 97:786-93. 2002
    ..The unprotected upper airway tends to obstruct during general anesthesia, yet its mechanical properties have not been studied in detail during this condition...
  33. ncbi request reprint Function of the lower esophageal sphincter during and after high-intensity exercise
    Kathleen J Maddison
    Department of Pulmonary Physiology, Sir Charles Gairdner Hospital, University of Western Australia, Nedlands, Australia
    Med Sci Sports Exerc 37:1728-33. 2005
    ..The aim of this study was to determine the influence of exercise with and without ingestion of fluid on the LES barrier pressure in asymptomatic individuals...
  34. ncbi request reprint The impact of continuous positive airway pressure on the lower esophageal sphincter
    Kelly L Shepherd
    West Australian Sleep Disorders Research Institute, Department of Pulmonary Physiology, Sir Charles Gairdner Hospital, Nedlands, Western Australia 6009, Australia
    Am J Physiol Gastrointest Liver Physiol 292:G1200-5. 2007
    ..The findings suggest CPAP may make the LES less susceptible to reflux by increasing Pb and decreasing the duration of LES relaxation...
  35. ncbi request reprint Volume displaced by diaphragm motion in emphysema
    B Singh
    Department of Pulmonary Physiology, Sir Charles Gairdner Hospital, University of Western Australia, Nedlands, Western Australia 6009, Australia
    J Appl Physiol 91:1913-23. 2001
    ..36 vs. 0.82 +/- 0.80 liters, P < 0.05). We conclude that DeltaVdi can be normal in emphysema because 1) hyperinflation is shared between ribcage and diaphragm, preserving Lap, and 2) the diaphragm remains flat during inspiration...
  36. ncbi request reprint The effects of learning on the ventilatory responses to inspiratory threshold loading
    P R Eastwood
    Department of Pulmonary Physiology, Sir Charles Gairdner Hospital, Nedlands, Western Australia, Australia
    Am J Respir Crit Care Med 158:1190-6. 1998
    ..Measurements from PTL should only be used to assess respiratory muscle performance after allowing time for learning...
  37. doi request reprint Managing obstruction of the central airways
    J P Williamson
    Department of Pulmonary Physiology, Sir Charles Gairdner Hospital, Western Australia 6009, Australia
    Intern Med J 40:399-410. 2010
    ....
  38. doi request reprint Measuring airway dimensions during bronchoscopy using anatomical optical coherence tomography
    J P Williamson
    Dept of Pulmonary Physiology, Level 5, G Block, Sir Charles Gairdner Hospital, Perth, Australia
    Eur Respir J 35:34-41. 2010
    ..Using aOCT with conventional bronchoscopy allows real-time measurement of airway dimensions and could be useful clinically in settings where knowledge of airway calibre is required...
  39. ncbi request reprint Comparison of incremental and constant load tests of inspiratory muscle endurance in COPD
    K Hill
    Department of Pulmonary Physiology, Sir Charles Gairdner Hospital, Hospital Avenue, Nedlands, Western Australia, Australia 6009
    Eur Respir J 30:479-86. 2007
    ..However, to attribute changes in these tests to improvements in inspiratory muscle endurance, breathing pattern should be controlled...
  40. doi request reprint Quantifying tracheobronchial tree dimensions: methods, limitations and emerging techniques
    J P Williamson
    Department of Pulmonary Physiology, Sir Charles Gairdner Hospital, Nedlands, Perth 6009, Australia
    Eur Respir J 34:42-55. 2009
    ..This article contributes to this understanding by providing a comprehensive review of current and emerging techniques for quantifying airway dimensions...
  41. ncbi request reprint Six minute walk distance in healthy subjects aged 55-75 years
    Bernadine Camarri
    School of Physiotherapy, Curtin University of Technology, Perth, Western Australia, Australia
    Respir Med 100:658-65. 2006
    ..This study was undertaken to determine 6MWD in a population-based sample of healthy subjects and to identify predictors of 6MWD in this group...
  42. doi request reprint Anatomical optical coherence tomography for long-term, portable, quantitative endoscopy
    Matthew S Leigh
    Optical Biomedical Engineering Laboratory OBEL, School of Electrical, Electronic and Computer Engineering, University of Western Australia, Crawley, W A 6009, Australia
    IEEE Trans Biomed Eng 55:1438-46. 2008
    ..Our experiments show that the instrument is capable of imaging subjects during sleep, and that it can record dynamic changes in airway size and shape...
  43. doi request reprint Improvement in aerobic capacity after an exercise program in sporadic inclusion body myositis
    Liam G Johnson
    Centre for Neuromuscular and Neurological Disorders, University of Western Australia, Perth, Western Australia
    J Clin Neuromuscul Dis 10:178-84. 2009
    ..The study aimed to investigate the effects of a combined functional and aerobic exercise program on aerobic capacity, muscle strength, and functional mobility in a group of patients with sporadic inclusion body myositis (IBM)...
  44. ncbi request reprint The effect of interstate travel on the sleep patterns and performance of elite Australian Rules footballers
    Louise K Richmond
    School of Human Movement and Exercise Science, University of Western Australia, Australia
    J Sci Med Sport 10:252-8. 2007
    ..05). All other measures of performance were similar at home and away. These results show that prior interstate travel has minimal effect on sleep quality and game performance in elite footballers...
  45. ncbi request reprint Respiratory muscle training: the con argument
    K Hill
    Department of Pulmonary Physiology, Sir Charles Gairdner Hospital, Nedlands, WA, Australia
    Chron Respir Dis 2:223-4. 2005
  46. ncbi request reprint Effect of asbestos-related pleural fibrosis on excursion of the lower chest wall and diaphragm
    B Singh
    Department of Pulmonary Physiology, Sir Charles Gairdner Hospital, Nedlands, Australia
    Am J Respir Crit Care Med 160:1507-15. 1999
    ..Reduction in the latter contribution was the main cause of restriction, because the reduction in volume contributed by the diaphragm was partly compensated by flattening of its dome...
  47. ncbi request reprint Inspiratory muscle performance in endurance athletes and sedentary subjects
    P R Eastwood
    Department of Pulmonary Physiology, Sir Charles Gairdner Hospital, Nedlands, Western Australia, Australia
    Respirology 6:95-104. 2001
    ..The aim of this study was to determine whether whole-body endurance training is associated with increased respiratory muscle strength and endurance...
  48. ncbi request reprint Quantitative upper airway imaging with anatomic optical coherence tomography
    Julian J Armstrong
    Optical Biomedical Engineering Laboratory, School of Electrical, Electronic, and Computer Engineering, University of Western Australia, 35 Stirling Highway, Crawley, Western Australia 6009
    Am J Respir Crit Care Med 173:226-33. 2006
    ..We describe an endoscopic optical technique (anatomic optical coherence tomography, aOCT) that provides quantitative real-time imaging of the internal anatomy of the human upper airway...
  49. ncbi request reprint Effect of surface tension of mucosal lining liquid on upper airway mechanics in anesthetized humans
    Jason P Kirkness
    Ludwig Engel Centre for Respiratory Research, Westmead Hospital and University of Sydney, Westmead, New South Wales, 2145, Australia
    J Appl Physiol 95:357-63. 2003
    ..Instillation of exogenous surfactant into the UA lowers the gamma of UAL, thus increasing UA patency and augmenting reopening of the collapsed airway...
  50. ncbi request reprint Comparison of upper airway collapse during general anaesthesia and sleep
    Peter R Eastwood
    Lancet 359:1207-9. 2002
    ..Our findings suggest that sleep-disordered breathing should be considered in all patients with a pronounced tendency for upper airway obstruction during anaesthesia or during recovery from it...