Bala Venkatesh

Summary

Country: Australia

Publications

  1. doi request reprint Continuation of statin therapy in patients with presumed infection: a randomized controlled trial
    Peter S Kruger
    Intensive Care Unit, Princess Alexandra Hospital, Ipswich Road, Wooloongabba, Brisbane, Australia
    Am J Respir Crit Care Med 183:774-81. 2011
  2. ncbi request reprint The ADRENAL study protocol: adjunctive corticosteroid treatment in critically ill patients with septic shock
    Bala Venkatesh
    Princess Alexandra Hospital and Wesley Hospital, University of Queensland, Brisbane, QLD, Australia
    Crit Care Resusc 15:83-8. 2013
  3. pmc Plasma acetate, gluconate and interleukin-6 profiles during and after cardiopulmonary bypass: a comparison of Plasma-Lyte 148 with a bicarbonate-balanced solution
    Paul G Davies
    DDepartment of Anaesthesia, Princess Alexandra Hospital, University of Queensland, Ipswich Road, Woolloongabba, QLD 4102, Australia
    Crit Care 15:R21. 2011
  4. pmc Unmeasured anions: the unknown unknowns
    Bala Venkatesh
    Crit Care 12:113. 2008
  5. ncbi request reprint Relationship between tissue hypoxia and apoptosis: a preliminary observational study
    Bala Venkatesh
    Department of Intensive Care, Princess Alexandra Hospital, Brisbane, QLD, Australia
    Crit Care Resusc 9:129-36. 2007
  6. ncbi request reprint Indices to quantify changes in intracranial and cerebral perfusion pressure by assessing agreement between hourly and semi-continuous recordings
    B Venkatesh
    Departments of Intensive Care, Princess Alexandra and Wesley Hospitals, University of Queensland, Ipswich Road, 4102 Woolloongabba, Queensland, Australia
    Intensive Care Med 30:510-3. 2004
  7. doi request reprint Interstitium: the next diagnostic and therapeutic platform in critical illness
    Bala Venkatesh
    Intensive Care, Princess Alexandra and Wesley Hospital, University of Queensland, Queensland, Australia
    Crit Care Med 38:S630-6. 2010
  8. ncbi request reprint Subcutaneous gas tensions closely track ileal mucosal gas tensions in a model of endotoxaemia without anaerobism
    Bala Venkatesh
    Department of Intensive Care, University of Queensland, Princess Alexandra Hospital, Woolloongabba and Wesley Hospital, Australia
    Intensive Care Med 31:447-53. 2005
  9. ncbi request reprint Relative adrenal insufficiency in sepsis: match point or deuce?
    Bala Venkatesh
    Princess Alexandra Hospital, Brisbane, QLD, Australia
    Crit Care Resusc 8:376-80. 2006
  10. pmc Clinical review: ketones and brain injury
    Hayden White
    Department of Intensive Care, Griffi ths University, Logan Hospital, Meadowbrook, Queensland 4131, Australia
    Crit Care 15:219. 2011

Detail Information

Publications81

  1. doi request reprint Continuation of statin therapy in patients with presumed infection: a randomized controlled trial
    Peter S Kruger
    Intensive Care Unit, Princess Alexandra Hospital, Ipswich Road, Wooloongabba, Brisbane, Australia
    Am J Respir Crit Care Med 183:774-81. 2011
    ..In patients on prior statin therapy who are hospitalized for acute infections, current literature is unclear on whether statins should be continued during their hospitalization...
  2. ncbi request reprint The ADRENAL study protocol: adjunctive corticosteroid treatment in critically ill patients with septic shock
    Bala Venkatesh
    Princess Alexandra Hospital and Wesley Hospital, University of Queensland, Brisbane, QLD, Australia
    Crit Care Resusc 15:83-8. 2013
    ..There is considerable global uncertainty on the role of low-dose corticosteroids in septic shock, which translates into variations in prescribing practices...
  3. pmc Plasma acetate, gluconate and interleukin-6 profiles during and after cardiopulmonary bypass: a comparison of Plasma-Lyte 148 with a bicarbonate-balanced solution
    Paul G Davies
    DDepartment of Anaesthesia, Princess Alexandra Hospital, University of Queensland, Ipswich Road, Woolloongabba, QLD 4102, Australia
    Crit Care 15:R21. 2011
    ..No published data exist on the peak plasma acetate and gluconate concentrations resulting from the use of Plasma-Lyte 148 during CPB...
  4. pmc Unmeasured anions: the unknown unknowns
    Bala Venkatesh
    Crit Care 12:113. 2008
    ..Both the anion gap and the strong ion gap are used as scanning tools for recognition of these anions. The mechanisms underlying these elevations and their significance require further clarification...
  5. ncbi request reprint Relationship between tissue hypoxia and apoptosis: a preliminary observational study
    Bala Venkatesh
    Department of Intensive Care, Princess Alexandra Hospital, Brisbane, QLD, Australia
    Crit Care Resusc 9:129-36. 2007
    ..This observational study examined the relationship between tissue hypoxia (PO2 of 30mmHg and 15mmHg) and the development of dysoxia and apoptosis...
  6. ncbi request reprint Indices to quantify changes in intracranial and cerebral perfusion pressure by assessing agreement between hourly and semi-continuous recordings
    B Venkatesh
    Departments of Intensive Care, Princess Alexandra and Wesley Hospitals, University of Queensland, Ipswich Road, 4102 Woolloongabba, Queensland, Australia
    Intensive Care Med 30:510-3. 2004
    ..Each of these indices relates the number of abnormal observations to the total number of observations taken...
  7. doi request reprint Interstitium: the next diagnostic and therapeutic platform in critical illness
    Bala Venkatesh
    Intensive Care, Princess Alexandra and Wesley Hospital, University of Queensland, Queensland, Australia
    Crit Care Med 38:S630-6. 2010
    ..In this review we explore how interstitial monitoring might be used as a platform for future diagnostics and therapy in critical illness...
  8. ncbi request reprint Subcutaneous gas tensions closely track ileal mucosal gas tensions in a model of endotoxaemia without anaerobism
    Bala Venkatesh
    Department of Intensive Care, University of Queensland, Princess Alexandra Hospital, Woolloongabba and Wesley Hospital, Australia
    Intensive Care Med 31:447-53. 2005
    ....
  9. ncbi request reprint Relative adrenal insufficiency in sepsis: match point or deuce?
    Bala Venkatesh
    Princess Alexandra Hospital, Brisbane, QLD, Australia
    Crit Care Resusc 8:376-80. 2006
  10. pmc Clinical review: ketones and brain injury
    Hayden White
    Department of Intensive Care, Griffi ths University, Logan Hospital, Meadowbrook, Queensland 4131, Australia
    Crit Care 15:219. 2011
    ....
  11. ncbi request reprint Protein losing enteropathy in critically ill adult patients with burns: a preliminary report
    Balasubramanian Venkatesh
    Intensive Care Unit, Princess Alexandra Hospital, University of Queensland, Australia
    Intensive Care Med 30:162-6. 2004
    ..This study characterised the presence of protein-losing enteropathy in adults with burns and examined the relationship between the magnitude of burn size and the severity of protein loss...
  12. doi request reprint Adrenocortical (dys)function in septic shock - a sick euadrenal state
    Bala Venkatesh
    Princess Alexandra and Wesley Hospitals, University of Queensland, Brisbane, Australia
    Best Pract Res Clin Endocrinol Metab 25:719-33. 2011
    ....
  13. ncbi request reprint Evidence of altered cortisol metabolism in critically ill patients: a prospective study
    Bala Venkatesh
    Department of Intensive Care, Princess Alexandra and Wesley Hospitals, University of Queensland, 4102, Queensland, Australia
    Intensive Care Med 33:1746-53. 2007
    ..No published data exist on the activity of this enzyme in critical illness...
  14. ncbi request reprint Examinations in intensive care medicine: an international perspective
    Bala Venkatesh
    Joint Faculty of Intensive Care Medicine, Melbourne, Vic, Australia
    Crit Care Resusc 9:259-63. 2007
  15. pmc Changes in serum adiponectin concentrations in critical illness: a preliminary investigation
    Bala Venkatesh
    Department of Intensive Care, Princess Alexandra and Wesley Hospitals, University of Queensland, Ipswich Road, QLD 4102, Woolloongabba, Australia
    Crit Care 13:R105. 2009
    ..Perturbations in adiponectin concentration have been associated with obesity and the metabolic syndrome. Data on adiponectin pathophysiology in critical illness are limited...
  16. ncbi request reprint Monitoring cerebral perfusion and oxygenation: an elusive goal
    B Venkatesh
    Department of Intensive Care Medicine, Princess Alexandra and Wesley Hospitals, and Division of Anaesthesia and Critical Care, University of Queensland, QLD 4102, Australia
    Crit Care Resusc 7:195-9. 2005
    ....
  17. ncbi request reprint Sick adrenal or sick euadrenal?
    Bala Venkatesh
    Princess Alexandra and Wesley Hospitals, and University of Queensland, Brisbane, QLD
    Crit Care Resusc 11:301-4. 2009
    ....
  18. pmc Measurement of tissue cortisol levels in patients with severe burns: a preliminary investigation
    Jeremy Cohen
    Burns Trauma and Critical Care Research Centre, University of Queensland, Herston 4006, Australia
    Crit Care 13:R189. 2009
    ....
  19. pmc Tissue accumulation of cephalothin in burns: a comparative study by microdialysis of subcutaneous interstitial fluid cephalothin concentrations in burn patients and healthy volunteers
    Andrew J Dalley
    Burns Trauma and Critical Care Research Centre, University of Queensland, Royal Brisbane and Women s Hospital, Brisbane, Queensland, Australia
    Antimicrob Agents Chemother 53:210-5. 2009
    ..The results demonstrate the potential fallibility of using healthy population models to extrapolate tissue pharmacodynamic predictions from plasma data for burn patients...
  20. pmc Prediction of hospital outcome in septic shock: a prospective comparison of tissue Doppler and cardiac biomarkers
    David J Sturgess
    School of Medicine, The University of Queensland, Princess Alexandra Hospital, Brisbane, Australia
    Crit Care 14:R44. 2010
    ..The contribution of fluid management and diastolic dysfunction to elevation of BNP was also evaluated...
  21. pmc Unbound cephalothin pharmacokinetics in adult burn patients are related to the elapsed time after injury
    Andrew J Dalley
    University of Queensland, Burns Trauma and Critical Care Research Centre, Royal Brisbane and Women s Hospital, Herston, Brisbane, Queensland, Australia
    Antimicrob Agents Chemother 53:5303-5. 2009
    ..Mean residence times and distribution volumes increased between 1 and 4 days posttrauma, suggesting that burn patient pharmacokinetics change during the initial fluid resuscitation phase of treatment...
  22. doi request reprint A multicenter randomized trial of atorvastatin therapy in intensive care patients with severe sepsis
    Peter Kruger
    Intensive Care Unit, Princess Alexandra Hospital, Wooloongabba, Brisbane, Australia
    Am J Respir Crit Care Med 187:743-50. 2013
    ..Observational studies link statin therapy with improved outcomes in patients with severe sepsis...
  23. ncbi request reprint Variability of cortisol assays can confound the diagnosis of adrenal insufficiency in the critically ill population
    Jeremy Cohen
    Department of Intensive Care, Ipswich Hospital, Chelmsford Avenue, 4305 QLD, Ipswich, Australia
    Intensive Care Med 32:1901-5. 2006
    ..To compare the total plasma cortisol values obtained from three widely used immunoassays and a high pressure liquid chromatography (HPLC) technique on samples obtained from patients with sepsis...
  24. pmc Plasma protein C levels in immunocompromised septic patients are significantly lower than immunocompetent septic patients: a prospective cohort study
    Rakshit Panwar
    Intensive Care, Monash Medical Centre, Clayton, VIC 3168, Australia
    J Hematol Oncol 2:43. 2009
    ..Before embarking on a trial of APC administration in immunocompromised septic patients, a preliminary study on plasma levels of protein C in this cohort is essential...
  25. doi request reprint Serial changes in plasma total cortisol, plasma free cortisol, and tissue cortisol activity in patients with septic shock: an observational study
    Jeremy Cohen
    Burns, Trauma, and Critical Care Research Centre, University of Queensland, Herston, Queensland, Australia
    Shock 37:28-33. 2012
    ..Changes in plasma and urinary F:E ratios suggest tissue modulation of 11-β hydroxysteroid dehydrogenase activity. Total plasma cortisol measurements may not reflect the global adrenal response in septic shock...
  26. ncbi request reprint Plasma free cortisol and B-type natriuretic peptide in septic shock
    David J Sturgess
    Department of Intensive Care Medicine, University of Queensland, Brisbane, Queensland, Australia
    Anaesth Intensive Care 40:95-8. 2012
    ..Acute Physiology and Chronic Health Evaluation III score and noradrenaline dose were independent predictors of plasma free cortisol...
  27. doi request reprint Cerebral perfusion pressure in neurotrauma: a review
    Hayden White
    Department of Critical Care, Logan Hospital, Griffiths University, Brisbane, Australia
    Anesth Analg 107:979-88. 2008
    ..As yet, there is no strong outcome evidence to support this approach. Until then, the current debate over the optimal approach to CPP management is likely to continue...
  28. ncbi request reprint Vitamin D measurement in the intensive care unit: methodology, clinical relevance and interpretation of a random value
    Anand Krishnan
    University of Queensland, Australia
    Inflamm Allergy Drug Targets 12:230-8. 2013
    ..1α,25(OH)2D3 may behave differently to 25-hydroxyvitamin D, both in plasma and at tissue level, in inflammatory states. Measurement of tissue 1α,25(OH)2D3 levels may provide the true estimate of vitamin D activity. ..
  29. ncbi request reprint Epidemiology and significance of coagulase-negative staphylococci isolated in blood cultures from critically ill adult patients
    Mahesh B Savithri
    Princess Alexandra Hospital, Brisbane, QLD, Australia
    Crit Care Resusc 13:103-7. 2011
    ..Little published data are available on the epidemiology and significance of coagulase-negative staphylococci (CoNS) in blood culture isolates among critically ill adult patients...
  30. pmc Clinical review: adiponectin biology and its role in inflammation and critical illness
    Katherine Robinson
    Intensive Care Unit, Wesley Hospital, Auchenflower, Brisbane, Queensland, Australia
    Crit Care 15:221. 2011
    ..The various options for modulation of serum adiponectin (recombinant adiponectin, thiazolidinediones) are discussed...
  31. doi request reprint A preliminary study of atorvastatin plasma concentrations in critically ill patients with sepsis
    Peter S Kruger
    Department of Intensive Care, Princess Alexandra Hospital, Ipswich Road, Woolloongabba, Brisbane, Australia
    Intensive Care Med 35:717-21. 2009
    ..A lack of published pharmacokinetic data on statins in sepsis has prompted concerns about their safety and toxicity. This study determined single dose pharmacokinetics of Atorvastatin administered orally to acutely ill patients...
  32. ncbi request reprint Assessment of tissue cortisol activity
    Jeremy Cohen
    Burns Trauma and Critical Care Research Centre, University of Queensland, Brisbane, QLD
    Crit Care Resusc 11:287-9. 2009
    ....
  33. pmc Acute fluid shifts influence the assessment of serum vitamin D status in critically ill patients
    Anand Krishnan
    Intensive Care Unit, Princess Alexandra Hospital, University of Queensland, Ipswich Road, Woolloongabba, QLD 4102, Australia
    Crit Care 14:R216. 2010
    ..Serum vitamin D concentrations in these studies were measured following resuscitation. It is unclear whether aggressive fluid resuscitation independently influences serum vitamin D...
  34. ncbi request reprint Comparison of the diagnostic accuracy of measured and calculated free cortisol in acutely ill patients using the Coolens equation
    Jeremy Cohen
    Royal Brisbane Hospital, Brisbane, Australia
    Crit Care Resusc 15:39-41. 2013
    ....
  35. ncbi request reprint Vitamin D in the ICU: anything new under the sun?
    Priya Nair
    Intensive Care Unit, St Vincent s Hospital, Sydney, NSW, Australia
    Crit Care Resusc 14:268-73. 2012
    ....
  36. doi request reprint Characterising adrenal function using directly measured plasma free cortisol in stable severe liver disease
    Terrence Tan
    Department of Gastroenterology and Hepatology, Princess Alexandra Hospital, Queensland, Australia
    J Hepatol 53:841-8. 2010
    ..Diagnosing AI is problematic owing to controversies in using total serum cortisol as a measure of adrenal function. No published data exist on directly measured plasma free cortisol (PFC) in patients with liver disease...
  37. doi request reprint The metabolic syndrome in critically ill patients
    Katherine Robinson
    Department of Intensive Care, Wesley Hospital, University of Queensland, Australia
    Best Pract Res Clin Endocrinol Metab 25:835-45. 2011
    ..The role of adiponectin in the metabolic abnormalities in both the metabolic syndrome and in sepsis are reviewed. The potential role of the pleiotropic effects of statins in the therapy of sepsis is also discussed...
  38. ncbi request reprint Monitoring tissue oxygenation during resuscitation of major burns
    B Venkatesh
    University of Queensland, Herston, Queensland, Australia
    J Trauma 50:485-94. 2001
    ..This observational study was undertaken to examine changes in tissue oxygenation indices during burn resuscitation...
  39. ncbi request reprint Accuracy of pleural fluid pH and PCO2 measurement in a blood gas analyser. Analysis of bias and precision
    B Venkatesh
    Department of Intensive Care, Royal Brisbane Hospital, University of Queensland, Herston, Australia
    Scand J Clin Lab Invest 59:619-26. 1999
    ..A BGA is reliable for pleural fluid pH measurements. Pleural fluid PCO2 measurements in a BGA have a concentration-dependent bias and imprecision. Anaerobic storage of specimens for pleural pH and PCO2 analysis is mandatory...
  40. ncbi request reprint Subcutaneous oxygen tensions provide similar information to ileal luminal CO2 tensions in an animal model of haemorrhagic shock
    B Venkatesh
    Department of Intensive Care, Royal Brisbane Hospital, Herston, Queensland, Australia
    Intensive Care Med 26:592-600. 2000
    ..We therefore compared continuous subcutaneous PO2 (PO2sc) and PCO2 (PCO2sc) with simultaneous continuous gut luminal PCO2 (PCO2gi) in an animal model of haemorrhagic shock and resuscitation...
  41. ncbi request reprint Accuracy of intramucosal pH calculated from arterial bicarbonate and the Henderson-Hasselbalch equation: assessment using simulated ischemia
    T J Morgan
    Division of Anesthesiology and Intensive Care, Royal Brisbane Hospital, Queensland, Australia
    Crit Care Med 27:2495-9. 1999
    ..To determine the accuracy of intramucosal pH (pHi) calculated using arterial bicarbonate instead of mucosal capillary bicarbonate in the Henderson-Hasselbalch equation...
  42. ncbi request reprint Continuous Intra-arterial Blood Gas Monitoring
    B Venkatesh
    Intensive Care Unit, Royal Brisbane Hospital, Brisbane, Queensland Australia
    Crit Care Resusc 1:150. 1999
    ..To review the technology and the role of continuous intra-arterial blood gas monitoring in critical illness...
  43. ncbi request reprint Blood in the gastrointestinal tract delays and blunts the PCO2 response to transient mucosal ischaemia
    B Venkatesh
    Department of Intensive Care, Royal Brisbane Hospital, University of Queensland, Australia
    Intensive Care Med 26:1108-15. 2000
    ..To determine whether the presence of blood in the gastrointestinal tract impairs the detection of splanchnic mucosal ischaemia by reducing the rate and magnitude of rise in gut luminal PCO2...
  44. ncbi request reprint Transient mesenteric ischaemic episodes tracked by continuous jejunal PCO2 monitoring during liquid feeding
    T J Morgan
    Division of Anesthesiology and Intensive Care, Royal Brisbane Hospital, Herston Road, Herston, Queensland 4029, Australia
    Intensive Care Med 27:1408-11. 2001
    ..To test the effect of liquid feeds on the responses to splanchnic ischaemia of a continuous rapid response PCO2 sensor inserted in the jejunum...
  45. ncbi request reprint Relative adrenal insufficiency in the intensive care population; background and critical appraisal of the evidence
    J Cohen
    Department of Intensive Care Medicine, Royal Brisbane and Women s Hospital, Brisbane, Queensland, Australia
    Anaesth Intensive Care 38:425-36. 2010
    ....
  46. doi request reprint Random measurements of adiponectin and IL-6 may not be indicative of the 24-h profile in critically ill patients
    Katherine Robinson
    Intensive Care Unit, The Wesley Hospital, University of Queensland, Brisbane, Australia
    Clin Endocrinol (Oxf) 79:892-8. 2013
    ..It is unclear whether a random adiponectin measurement adequately reflects the 24-h profile in critically ill patients...
  47. pmc Tissue Doppler in critical illness: a retrospective cohort study
    David J Sturgess
    The University of Queensland, Department of Intensive Care, Brisbane, Australia
    Crit Care 11:R97. 2007
    ....
  48. ncbi request reprint Evidence-based evolution of the high-stakes postgraduate intensive care examination in Australia and New Zealand
    Richard P Lee
    Joint Faculty of Intensive Care Medicine, Australian and New Zealand College of Anaesthetists and Royal Australasian College of Physicians, Melbourne, Vic
    Crit Care Resusc 11:144-50. 2009
    ..To date, there have been 800 presentations to the exam, with 498 successful candidates...
  49. ncbi request reprint Stability of the strong ion gap versus the anion gap over extremes of PCO2 and pH
    T J Morgan
    Department of Chemical Pathology, Mater Health Services, Brisbane, Queensland, Australia
    Anaesth Intensive Care 35:370-3. 2007
    ..01; hypoalbuminaemic blood: 16.5 (0.8) mEq/l versus 11.8 (2.0) mEq/l, P < 0.05). We conclude that, unlike the AG, the SIG is not affected by severe respiratory acidosis and alkalosis, enhancing its utility in acid-base disturbances...
  50. ncbi request reprint High-stakes assessment of the non-technical skills of critical care trainees using simulation: feasibility, acceptability and reliability
    Leo Nunnink
    University of Queensland, Brisbane, QLD, Australia
    Crit Care Resusc 16:6-12. 2014
    ....
  51. ncbi request reprint The compatibility of a low concentration of hydrocortisone sodium succinate with selected drugs during a simulated Y-site administration
    Andrew J Semark
    Department of Intensive Care Medicine, Princess Alexandra Hospital, Brisbane, QLD, Australia
    Crit Care Resusc 15:63-6. 2013
    ....
  52. ncbi request reprint The use of hypertonic saline for treating intracranial hypertension after traumatic brain injury
    Hayden White
    Department of Anesthesiology, QE II Hospital, Princess Alexandra Hospital, University of Queensland, Brisbane, Australia
    Anesth Analg 102:1836-46. 2006
    ..There are few clinical studies in traumatic brain injury with patient survival as an end point. In this review, we examined the experimental and clinical knowledge of hypertonic saline as an osmotherapeutic agent in neurotrauma...
  53. ncbi request reprint Basic science research in Australian intensive care practice
    Gordon A Laurie
    Department of Intensive Care, Wesley Hospital, Brisbane, QLD, Australia
    Crit Care Resusc 10:52. 2008
    ....
  54. doi request reprint Use of a nurse-led intervention to optimize beta-blockade for reducing cardiac events after major noncardiac surgery
    Thomas H Marwick
    University of Queensland, Brisbane, Australia
    Am Heart J 157:784-90. 2009
    ..We sought whether optimizing beta-blockade (BB) delivery could make them more effective...
  55. doi request reprint The role of hypertonic saline in neurotrauma
    H White
    QE II Hospital, Department of Anesthesiology, Brisbane, Australia
    Eur J Anaesthesiol Suppl 42:104-9. 2008
    ..Hypertonic saline may be considered a therapeutic adjunct to the medical management of traumatic brain injury, awaiting definitive evidence to support routine use...
  56. ncbi request reprint A clinician's guide to predicting fluid responsiveness in critical illness: applied physiology and research methodology
    D J Sturgess
    School of Medicine, University of Queensland, Princess Alexandra Hospital, Wolloongabba, Queensland, Australia
    Anaesth Intensive Care 35:669-78. 2007
    ..In addition, the potential importance of methodological differences in the cutrent literature will be considered...
  57. ncbi request reprint Acid-base and bio-energetics during balanced versus unbalanced normovolaemic haemodilution
    T J Morgan
    University of Queensland Intensive Care Laboratories, Royal Brisbane Hospital, Brisbane, Queensland, Australia
    Anaesth Intensive Care 35:173-9. 2007
    ..We conclude that a crystalloid SID of 24 mEq/l provides balanced haemodilution. Bio-energetic perturbations with higher SID haemodilution may be more severe and need further investigation...
  58. doi request reprint Are there any benefits from statin treatment for the septic patient?
    Peter S Kruger
    Anaesthesia and Intensive Care, University of Queensland, Brisbane, QLD, Australia
    Curr Atheroscler Rep 16:378. 2014
    ..Further studies are required to address fundamental issues such as efficacy, potential target patient populations, dose, class equivalence and safety...
  59. ncbi request reprint Inadequate antimicrobial prophylaxis during surgery: a study of beta-lactam levels during burn debridement
    Andrew J Dalley
    Burns Trauma and Critical Care Research Centre, University of Queensland, Brisbane, Queensland, Australia
    J Antimicrob Chemother 60:166-9. 2007
    ..To determine how long single-dose prophylactic antibiotic regimens for burns surgery maintained plasma concentrations above the MICs for target organisms during surgery...
  60. ncbi request reprint Not all unexplained hyperkalaemia is pseudohyperkalaemia
    Goce Dimeski
    Department of Chemical Pathology, Pathology Queensland, Princess Alexandra Hospital, Brisbane, QLD
    Crit Care Resusc 11:219-21. 2009
    ..This report highlights the importance of systematic scrutiny of pathology results, especially when they do not fit the "clinical picture", and the crucial role of the laboratory in aiding the clinician...
  61. ncbi request reprint Information on the Internet about head injury pertaining to intensive care: less quantity and more quality is needed
    Benjamin K Cheung
    Department of Intensive Care, Princess Alexandra Hospital, Brisbane, QLD, Australia
    Crit Care Resusc 8:100-6. 2006
    ..This study investigated the accuracy of health information about head injury pertaining to intensive care on the Internet, and correlated website characteristics with the quality of their content...
  62. ncbi request reprint Continuous measurement of cerebral blood flow velocity using transcranial Doppler reveals significant moment-to-moment variability of data in healthy volunteers and in patients with subarachnoid hemorrhage
    Bala Venkatesh
    Royal Brisbane Hospital, Herston, Queensland, Australia
    Crit Care Med 30:563-9. 2002
    ....
  63. ncbi request reprint Evaluation of random plasma cortisol and the low dose corticotropin test as indicators of adrenal secretory capacity in critically ill patients: a prospective study
    B Venkatesh
    Department of Intensive Care, Royal Brisbane Hospital, Queensland
    Anaesth Intensive Care 33:201-9. 2005
    ..We suggest that caution be exercised when drawing conclusions on the adequacy of adrenal function based on a single random plasma cortisol or the corticotropin test...
  64. ncbi request reprint Evidence-based evolution of the high stakes postgraduate intensive care examination in Australia and New Zealand
    R P Lee
    Joint Faculty of Intensive Care Medicine, Ulimaroa, Victoria, Australia
    Anaesth Intensive Care 37:525-31. 2009
    ..To date, there have been 800 presentations to the exam with 498 successful candidates...
  65. ncbi request reprint Equivalent metabolic acidosis with four colloids and saline on ex vivo haemodilution
    T J Morgan
    Adult Intensive Care Unit and Department of Chemical Pathology, Mater Health Services, Brisbane, Queensland, Australia
    Anaesth Intensive Care 37:407-14. 2009
    ..By proportionally increasing the strong ion difference, these modifications counter deviations from pure saline effects caused by colloid weak acid activity. Extrapolation in vivo requires further investigation...
  66. ncbi request reprint Serum procalcitonin and C-reactive protein as markers of sepsis and outcome in patients with neurotrauma and subarachnoid haemorrhage
    E Oconnor
    Department of Intensive Care, Royal Brisbane Hospital, Queensland
    Anaesth Intensive Care 32:465-70. 2004
    ..Further clinical trials with larger sample sizes are required to confirm any potential role of PCT as a sepsis and outcome indicator in patients with head injuries or subarachnoid haemorrhage...
  67. ncbi request reprint A prospective comparison between written examination and either simulation-based or oral viva examination of intensive care trainees' procedural skills
    L Nunnink
    Intensive Care Unit, Princess Alexandra Hospital, Brisbane, Queensland, Australia
    Anaesth Intensive Care 38:876-82. 2010
    ..We hypothesise that identification of critical candidate errors in a simulation format exam that were not exposed in a written exam may indicate better predictive validity for simulation format examination of procedural skills...
  68. ncbi request reprint B-type natriuretic peptide concentrations and myocardial dysfunction in critical illness
    D J Sturgess
    Department of Intensive Care, Princess Alexandra Hospital, University of Queensland, Brisbane, Queensland, Australia
    Anaesth Intensive Care 34:151-63. 2006
    ..Continued research should augment the validity of BNP assay in the evaluation of myocardial function in patients with life-threatening illness...
  69. ncbi request reprint Changes in serum procalcitonin and C-reactive protein following antimicrobial therapy as a guide to antibiotic duration in the critically ill: a prospective evaluation
    B Venkatesh
    Intensive Care Unit, Princess Alexandra Hospital, Brisbane, Queensland, Australia
    Anaesth Intensive Care 37:20-6. 2009
    ..The marked variability and overlap in plasma profile of these markers between CP and CN sepsis makes it difficult to define a nadir plasma concentration at which one can recommend discontinuation of antibiotic therapy...
  70. ncbi request reprint A comparison of transcutaneous Doppler corrected flow time, b-type natriuretic peptide and central venous pressure as predictors of fluid responsiveness in septic shock: a preliminary evaluation
    D J Sturgess
    Department of Intensive Care, The Wesley Hospital, Brisbane, Queensland, Australia
    Anaesth Intensive Care 38:336-41. 2010
    ..Transcutaneous aortic Doppler FTc offers promise as a simple, completely non-invasive predictor of fluid responsiveness and should be evaluated further..
  71. ncbi request reprint Acid-base effects of a bicarbonate-balanced priming fluid during cardiopulmonary bypass: comparison with Plasma-Lyte 148. A randomised single-blinded study
    T J Morgan
    Department of Anaesthesia, Princess Alexandra Hospital, Brisbane, Queensland, Australia
    Anaesth Intensive Care 36:822-9. 2008
    ..These are likely to be gluconate and/or acetate. Whether surges of exogenous anions during bypass can be harmful requires further study...
  72. ncbi request reprint Venous thromboembolism prophylaxis in the critically ill: a point prevalence survey of current practice in Australian and New Zealand intensive care units
    Megan S Robertson
    Epworth Healthcare, Melbourne, Vic
    Crit Care Resusc 12:9-15. 2010
    ..There are limited data describing current VTE prophylaxis regimens in Australia and New Zealand...
  73. ncbi request reprint Sodium crocetinate does not alter gut hypercapnic responses or renal energy stores during transient sub-diaphragmatic ischaemia
    Thomas J Morgan
    Adult Intensive Care, Mater Misericordiae Health Services, Raymond Terrace, 4101, South Brisbane, Queensland, Australia
    Intensive Care Med 29:652-4. 2003
    ..To evaluate the protection afforded by trans-sodium crocetinate against dysoxia in an animal model of recurrent sub-diaphragmatic ischaemia...
  74. ncbi request reprint Nitric oxide synthase inhibition in sepsis? Lessons learned from large-animal studies
    Balázs Hauser
    Sektion Anasthesiologische Pathophysiologie und Verfahrensentwicklung, Universitatsklinikum, Parkstrasse 11, D 89073 Ulm, Germany
    Anesth Analg 101:488-98. 2005
    ..Therefore, the present review focuses on clinically relevant large-animal studies of endotoxin or living bacteria-induced, hyperdynamic models of sepsis that integrate standard day-to-day care resuscitative measures...
  75. ncbi request reprint Crystalloid strong ion difference determines metabolic acid-base change during in vitro hemodilution
    Thomas J Morgan
    Division of Anesthesiology and Intensive Care, Royal Brisbane Hospital, Queensland, Australia
    Crit Care Med 30:157-60. 2002
    ..To determine the relationship between the strong ion difference (SID) of a diluting crystalloid and its metabolic acid-base effects on in vitro blood dilution...
  76. ncbi request reprint Evaluation of the P-POSSUM mortality prediction algorithm in Australian surgical intensive care unit patients
    Nicole Organ
    Royal Brisbane Hospital, Herston, Queensland, Australia
    ANZ J Surg 72:735-8. 2002
    ..A single-centre retrospective study was therefore performed to determine the applicability of this tool to the Australian surgical case mix...
  77. ncbi request reprint Applications of transcranial Doppler in the ICU: a review
    Hayden White
    Queen Elizabeth II Hospital, Department of Anaesthesia, Coopers Plains, QLD, Australia
    Intensive Care Med 32:981-94. 2006
    ..This review critically evaluates the evidence for the use of TCD in the critical care population...
  78. ncbi request reprint Sample introduction mode: another source of error in saline PCO2 measurement
    Balasubramanian Venkatesh
    Intensive Care Med 28:1676-7. 2002
  79. ncbi request reprint Crystalloid strong ion difference determines metabolic acid-base change during acute normovolaemic haemodilution
    Thomas J Morgan
    Adult Intensive Care Unit, Mater Misericordiae Hospital, Raymond Terrace, 4101 South Brisbane, Queensland, Australia
    Intensive Care Med 30:1432-7. 2004
    ..To study the acid-base effects of crystalloid strong ion difference (SID) during haemodilution...
  80. ncbi request reprint The parp-1 inhibitor ino-1001 facilitates hemodynamic stabilization without affecting DNA repair in porcine thoracic aortic cross-clamping-induced ischemia/reperfusion
    Balázs Hauser
    Sektion Anasthesiologische Pathophysiologie und Verfahrensentwicklung, Universitatsklinikum, Ulm, Germany
    Shock 25:633-40. 2006
    ..The reduced norepinephrine requirements during reperfusion suggest a positive inotropic effect of INO-1001, as demonstrated by other authors. In our model, INO-1001 proved to be safe with respect to DNA repair...
  81. doi request reprint Epidemiology and 12-month outcomes from traumatic brain injury in australia and new zealand
    John A Myburgh
    Department of Intensive Care, The St George Hospital, Sydney, Australia
    J Trauma 64:854-62. 2008
    ..An epidemiologic profile of traumatic brain injury (TBI) in Australia and New Zealand was obtained following the publication of international evidence-based guidelines...