Research Topics
| Murat YucelSummaryAffiliation: University of Melbourne Country: Australia Publications
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Publications
Inhibitory control in young adolescents: the role of sex, intelligence, and temperamentMurat Yucel
The University of Melbourne, Melbourne Health, Melbourne, Victoria, Australia
Neuropsychology 26:347-56. 2012..However, sex differences in inhibitory control are often not expressed experimentally during task performance. Here, we sought to examine how sex, temperament, and intelligence are related to different aspects of inhibitory control...
The impact of cannabis use on cognitive functioning in patients with schizophrenia: a meta-analysis of existing findings and new data in a first-episode sampleMurat Yucel
Melbourne Neuropsychiatry Centre, Department of Psychiatry, University of Melbourne and Melbourne Health, National Neuroscience Facility, Alan Gilbert Building, 161 Barry Street, Carlton South, Victoria 3053, Australia
Schizophr Bull 38:316-30. 2012....
Understanding drug addiction: a neuropsychological perspectiveMurat Yucel
ORYGEN Research Centre, Department of Psychiatry, University of Melbourne, Melbourne, Victoria, Australia
Aust N Z J Psychiatry 41:957-68. 2007..Presented herein is a neuropsychological model of addictive behaviour that highlights the complex interplay between cognition, brain maturation, psychopathology and drug exposure...- State, trait and biochemical influences on human anterior cingulate functionMurat Yucel
Melbourne Neuropsychiatry Centre, Australia
Neuroimage 34:1766-73. 2007..They also highlight the importance of considering enduring personal characteristics when mapping human brain-behavior relationships... - Anterior cingulate activation in antipsychotic-naïve first-episode schizophreniaM Yucel
Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne, Melbourne, Carlton South, VIC 3053, Australia
Acta Psychiatr Scand 115:155-8. 2007..Anterior cingulate (ACC) hypo-activity is commonly observed in chronically ill schizophrenia patients. However, it is unclear whether this is secondary to persistent illness and/or medication... - A combined spectroscopic and functional MRI investigation of the dorsal anterior cingulate region in opiate addictionM Yucel
ORYGEN Research Centre, Melbourne, Vic, Australia
Mol Psychiatry 12:611, 691-702. 2007.... - White-matter abnormalities in adolescents with long-term inhalant and cannabis use: a diffusion magnetic resonance imaging studyMurat Yucel
Orygen Youth Health Research Centre, 35 Poplar Rd, Parkville, Victoria 3052, Australia
J Psychiatry Neurosci 35:409-12. 2010.... - Neurocognitive and neuroimaging evidence of behavioural dysregulation in human drug addiction: implications for diagnosis, treatment and preventionMurat Yucel
Department of Psychiatry, The University of Melbourne, ORYGEN Research Centre, and Melbourne Neuropsychiatry Centre, Melbourne, Victoria, Australia
Drug Alcohol Rev 26:33-9. 2007.... - Toluene misuse and long-term harms: a systematic review of the neuropsychological and neuroimaging literatureMurat Yucel
ORYGEN Research Centre, Department of Psychiatry, The University of Melbourne, Victoria, Australia
Neurosci Biobehav Rev 32:910-26. 2008..We also propose a set of recommendations to guide future research in this area... - Functional and biochemical alterations of the medial frontal cortex in obsessive-compulsive disorderMurat Yucel
Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne and Melbourne Health, Victoria 3053, Australia
Arch Gen Psychiatry 64:946-55. 2007..However, the precise regions and the neural alterations associated with this abnormality remain unclear... - Anterior cingulate glutamate-glutamine levels predict symptom severity in women with obsessive-compulsive disorderMurat Yucel
Melbourne Neuropsychiatry Centre, National Neuroscience Facility, Carlton South, Australia
Aust N Z J Psychiatry 42:467-77. 2008..The purpose of the present study was to investigate how ACC biochemistry in OCD varies as a function of gender, hemisphere, subregion, and symptomatology... - Regional brain abnormalities associated with long-term heavy cannabis useMurat Yucel
MAPS, ORYGEN Research Centre, 35 Poplar Rd, Melbourne, Victoria, Australia
Arch Gen Psychiatry 65:694-701. 2008..Cannabis is the most widely used illicit drug in the developed world. Despite this, there is a paucity of research examining its long-term effect on the human brain... - Prevalence of large cavum septi pellucidi in ultra high-risk individuals and patients with psychotic disordersTsutomu Takahashi
Melbourne Neuropsychiatry Centre, Department of Psychiatry, University of Melbourne and Melbourne Health, Victoria, Australia
Schizophr Res 105:236-44. 2008..These findings suggest that the CSP is not a neurodevelopmental marker of psychosis and cast doubt over the notion that it plays a major role in the neurobiology of psychosis... - Dysfunction of dorsolateral prefrontal cortex in antipsychotic-naïve schizophreniform psychosisBen J Harrison
Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne, Australia
Psychiatry Res 148:23-31. 2006.... - Functional connectivity during Stroop task performanceBen J Harrison
Brain Sciences Institute, Swinburne University of Technology, Melbourne, Australia
Neuroimage 24:181-91. 2005..These findings may also provide some additional insight into the nature of anterior cingulate- and prefrontal cortical contributions to implementing cognitive control in the brain... - Functional connectivity in brain networks underlying cognitive control in chronic cannabis usersIan H Harding
Department of Psychiatry, Melbourne Neuropsychiatry Centre, University of Melbourne and Melbourne Health, Melbourne, Vic, Australia
Neuropsychopharmacology 37:1923-33. 2012.... - Anterior cingulate cortex abnormalities associated with a first psychotic episode in bipolar disorderAlex Fornito
Melbourne Neuropsychiatry Centre, Department of Psychiatry, School of Behavioural Science, University of Melbourne, National Neuroscience Facility, 161 Barry Street, Carlton South, VIC 3053, Australia
Br J Psychiatry 194:426-33. 2009.... - Hippocampal pathology in individuals at ultra-high risk for psychosis: a multi-modal magnetic resonance studyStephen J Wood
Melbourne Neuropsychiatry Centre, Department of Psychiatry, University of Melbourne and Melbourne Health, Parkville, Vic, Australia
Neuroimage 52:62-8. 2010..However, standard measures of neuroanatomical disturbance do not appear to be predictive of later transition, and instead are likely to be non-specific and common in cases that later develop a non-psychotic disorder... - Surface-based morphometry of the anterior cingulate cortex in first episode schizophreniaAlex Fornito
Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne and Melbourne Health, Australia
Hum Brain Mapp 29:478-89. 2008.... - Interaction of parenting experiences and brain structure in the prediction of depressive symptoms in adolescentsMarie B H Yap
ORYGEN Research Centre, Parkville, Victoria, Australia
Arch Gen Psychiatry 65:1377-85. 2008..One potential explanation for this is the moderating role of environmental context, with individuals differing in their biological sensitivity to context... - Volumetric MRI study of the insular cortex in individuals with current and past major depressionTsutomu Takahashi
Melbourne Neuropsychiatry Centre, Department of Psychiatry, University of Melbourne and Melbourne Health, Victoria 3053, Australia
J Affect Disord 121:231-8. 2010..Nevertheless, it remains largely unknown whether MDD patients exhibit morphologic changes of the insular cortex, and whether such changes reflect state or trait markers of the disorder... - Neuroanatomical correlates of temperament in early adolescentsSarah Whittle
Department of Psychiatry, University of Melbourne, Victoria 3052, Australia
J Am Acad Child Adolesc Psychiatry 47:682-93. 2008..In the present study, we examined the relation between four core temperament dimensions and anatomically defined regions of the limbic and prefrontal cortices... - Adolescents' depressive symptoms moderate neural responses to their mothers' positive behaviorSarah Whittle
Orygen Youth Health Research Centre, Locked Bag 10, Parkville, VIC 3052, Australia
Soc Cogn Affect Neurosci 7:23-34. 2012..This study represents an important step in furthering our understanding of the neural basis of affective processing in adolescents. Further, the results support a disruption of reward function in depression... - Adhesio interthalamica in individuals at high-risk for developing psychosis and patients with psychotic disordersTsutomu Takahashi
Melbourne Neuropsychiatry Centre, Department of Psychiatry, University of Melbourne and Melbourne Health, Victoria, Australia
Prog Neuropsychopharmacol Biol Psychiatry 32:1708-14. 2008.... - Anatomic abnormalities of the anterior cingulate cortex before psychosis onset: an MRI study of ultra-high-risk individualsAlex Fornito
Department of Psychiatry, Melbourne Neuropsychiatry Centre, University of Melbourne, Carlton South, Victoria, Australia
Biol Psychiatry 64:758-65. 2008..In this study, we characterized prepsychotic ACC abnormalities in a sample of individuals at ultra-high-risk (UHR) for psychosis... - Gray matter reduction of the superior temporal gyrus in patients with established bipolar I disorderTsutomu Takahashi
Melbourne Neuropsychiatry Centre, Department of Psychiatry, University of Melbourne and Melbourne Health, Victoria, Australia
J Affect Disord 123:276-82. 2010..Functional abnormalities of the superior temporal gyrus (STG) have been implicated in the pathophysiology of bipolar disorder, but magnetic resonance imaging (MRI) studies of this region have yielded inconsistent findings... - Midline brain abnormalities in established bipolar affective disorderTsutomu Takahashi
Department of Psychiatry, University of Melbourne and Melbourne Health, Melbourne Neuropsychiatry Centre, Victoria, Australia
J Affect Disord 122:301-5. 2010..Morphologic changes of cortico-limbic regions have been reported in bipolar disorder, but it remains unclear whether midline brain abnormalities relevant to cortico-limbic connectivity are also present... - Increased prefrontal cerebral blood flow in first-episode schizophrenia following treatment: longitudinal positron emission tomography studyWarrick J Brewer
ORYGEN Research Centre, Locked Bag 10, Parkville, VIC 3052, Australia and Early Psychosis Prevention and Intervention Centre, Department of Psychiatry, University of Melbourne, Melbourne, Victoria, Australia
Aust N Z J Psychiatry 41:129-35. 2007..The objective of the current study was to investigate executive-control related neural activity from first onset of the illness through to symptom stabilization... - Brain functional connectivity during induced sadness in patients with obsessive-compulsive disorderLeonardo F Fontenelle
Melbourne Neuropsychiatry Centre, Department of Psychiatry, University of Melbourne and Melbourne Health, Australia
J Psychiatry Neurosci 37:231-40. 2012.... - Pituitary volume mediates the relationship between pubertal timing and depressive symptoms during adolescenceSarah Whittle
Orygen Youth Health Research Centre, Centre for Youth Mental Health, University of Melbourne, Australia
Psychoneuroendocrinology 37:881-91. 2012.... - Variations in cortical folding patterns are related to individual differences in temperamentSarah Whittle
ORYGEN Research Centre, Department of Psychiatry, The University of Melbourne, Victoria, Australia
Psychiatry Res 172:68-74. 2009..These findings suggest that early neurodevelopmental processes contribute to individual differences in temperament. They also illustrate sexual dimorphisms in the neural underpinnings of temperament... - Effect of long-term cannabis use on axonal fibre connectivityAndrew Zalesky
Melbourne Neuropsychiatry Centre, The University of Melbourne and Melbourne Health, Melbourne, 3053, Australia
Brain 135:2245-55. 2012..Our findings indicate long-term cannabis use is hazardous to the white matter of the developing brain. Delaying the age at which regular use begins may minimize the severity of microstructural impairment... - Orbitofrontal, amygdala and hippocampal volumes in teenagers with first-presentation borderline personality disorderAndrew M Chanen
ORYGEN Research Centre, Department of Psychiatry, The University of Melbourne, Melbourne, Australia
Psychiatry Res 163:116-25. 2008..Hippocampal and amygdala volume reductions observed in adult BPD samples might develop during the course of the disorder, although longitudinal studies are needed to examine this... - Superior temporal gyrus volume in teenagers with first-presentation borderline personality disorderTsutomu Takahashi
Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne and Melbourne Health, Melbourne, Australia
Psychiatry Res 182:73-6. 2010..Our preliminary findings might reflect the neurobiological heterogeneity of the disorder... - Theory of mind impairment in schizophrenia: meta-analysisEmre Bora
Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne and Melbourne Health, Vic, Australia
Schizophr Res 109:1-9. 2009..Our review also suggests that future research should consider the potential moderating influence of IQ deficits on ToM performance in "remitted" patients, as well as the potential effects of residual symptoms... - Anterior cingulate volume in adolescents with first-presentation borderline personality disorderSarah Whittle
ORYGEN Research Centre, Department of Psychiatry, The University of Melbourne, Melbourne, Australia
Psychiatry Res 172:155-60. 2009..Longitudinal studies are needed to examine the nature of this abnormality over the course of the disorder... - An MRI study of the superior temporal subregions in patients with current and past major depressionTsutomu Takahashi
Melbourne Neuropsychiatry Centre, Department of Psychiatry, University of Melbourne and Melbourne Health, Victoria, Australia
Prog Neuropsychopharmacol Biol Psychiatry 34:98-103. 2010.... - Morphology of the paracingulate sulcus and executive cognition in schizophreniaAlex Fornito
Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne, National Neuroscience Facility, Levels 2 and 3, Alan Gilbert Building, 161 Barry St, Carlton South, Victoria 3053, Australia
Schizophr Res 88:192-7. 2006..This suggests that prior reports of impaired performance on such tasks in schizophrenia may be partly explained by the reduced frequency of a leftward PCS asymmetry in this population... - Evaluating brain activity in obsessive-compulsive disorder: preliminary insights from a multivariate analysisBen J Harrison
Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne, Melbourne, Victoria, Australia
Psychiatry Res 147:227-31. 2006..Implications for the analysis of such studies are discussed... - Hippocampal volume and sensitivity to maternal aggressive behavior: a prospective study of adolescent depressive symptomsSarah Whittle
University of Melbourne, Melbourne, Victoria, Australia
Dev Psychopathol 23:115-29. 2011..Given that family context risk factors are modifiable, our findings suggest the potential utility of targeted parenting interventions for the prevention and treatment of adolescent depressive disorder... - Insular cortex volume and impulsivity in teenagers with first-presentation borderline personality disorderTsutomu Takahashi
Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne and Melbourne Health, Melbourne, Australia
Prog Neuropsychopharmacol Biol Psychiatry 33:1395-400. 2009..Further studies are needed to clarify whether the potential relationship between the insular cortex volume and impulsivity is specific to BPD... - Amygdala and insula volumes prior to illness onset in bipolar disorder: a magnetic resonance imaging studyAndreas Bechdolf
Department of Psychiatry, University of Cologne, Germany
Psychiatry Res 201:34-9. 2012..If these findings are confirmed, they suggest that imaging investigations could help to distinguish people who will subsequently develop bipolar disorder from those who will not, at least in symptomatically enriched samples... - From neuroprogression to neuroprotection: implications for clinical careMichael Berk
Department of Clinical and Biomedical Sciences Barwon Health, University of Melbourne, Melbourne, Vic
Med J Aust 193:S36-40. 2010..These developments need to be combined with service initiatives to maximise the opportunities for early diagnosis and intervention... - Insular cortex volume in established bipolar affective disorder: a preliminary MRI studyTsutomu Takahashi
Melbourne Neuropsychiatry Centre, Department of Psychiatry, University of Melbourne and Melbourne Health, 161 Barry Street, Carlton South, Victoria 3053, Australia
Psychiatry Res 182:187-90. 2010.... - Midline brain structures in teenagers with first-presentation borderline personality disorderTsutomu Takahashi
Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne and Melbourne Health, Melbourne, Australia
Prog Neuropsychopharmacol Biol Psychiatry 33:842-6. 2009..These preliminary findings suggest that ongoing neuroimaging studies should further evaluate a potential involvement of midline brain structures in the pathogenesis of BPD... - Structural brain abnormalities in major depressive disorder: a selective review of recent MRI studiesValentina Lorenzetti
Melbourne Neuropsychiatry Centre, Department of Psychiatry, Australia
J Affect Disord 117:1-17. 2009..While there is evidence to suggest that major depressive disorder (MDD) is associated with structural brain abnormalities, the precise nature of these abnormalities remains unclear... - Responsiveness to drug cues and natural rewards in opiate addiction: associations with later heroin useDan I Lubman
ORYGEN Research Centre, 35 Poplar Road, Parkville, Victoria 3052, Australia
Arch Gen Psychiatry 66:205-12. 2009..Although drug cues reliably activate the brain's reward system, studies rarely examine how the processing of drug stimuli compares with natural reinforcers or relates to clinical outcomes... - Anatomical abnormalities of the anterior cingulate cortex in schizophrenia: bridging the gap between neuroimaging and neuropathologyAlex Fornito
Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne, Victoria, Australia
Schizophr Bull 35:973-93. 2009..We discuss the potential mechanisms that might facilitate integration of these findings and consider strategies for future research... - Evidence for neuronal dysfunction in the anterior cingulate of patients with schizophrenia: a proton magnetic resonance spectroscopy study at 3 TStephen J Wood
Melbourne Neuropsychiatry Centre, Department of Psychiatry, University of Melbourne, Australia
Schizophr Res 94:328-31. 2007..Anterior cingulate involvement in schizophrenia is likely to be a result of neuronal loss or dysfunction... - Executive control among adolescent inhalant and cannabis usersMichael Takagi
Orygen Youth Health Research Centre, Centre for Youth Mental Health, University of Melbourne, Melbourne, Australia
Drug Alcohol Rev 30:629-37. 2011..g. polysubstance use). The aim of the current study was to examine possible deficits in cognitive control among young, regular inhalant users and explore the relationship between inhalant use and executive functioning... - Functional alterations of large-scale brain networks related to cognitive control in obsessive-compulsive disorderLuca Cocchi
Melbourne Neuropsychiatry Centre, The University of Melbourne, Australia
Hum Brain Mapp 33:1089-106. 2012..The goal of this study was to extend such observations by investigating large-scale brain functional network correlates of cognitive-control performance in OCD patients... - Paracingulate morphologic differences in males with established schizophrenia: a magnetic resonance imaging morphometric studyMurat Yucel
Cognitive Neuropsychiatry Research and Academic Unit, Department of Psychiatry, The University of Melbourne, Sunshine Hospital, Melbourne, Victoria, Australia
Biol Psychiatry 52:15-23. 2002..Given the evidence showing an absence or reversal of normal anatomical asymmetries in patients with schizophrenia, the current study examined the anterior cingulate cortex sulcal-gyral patterns in patients with schizophrenia... - Orbitofrontal volumes in early adolescence predict initiation of cannabis use: a 4-year longitudinal and prospective studyAli Cheetham
Orygen Youth Health Research Centre, Centre for Youth Mental Health, University of Melbourne, Parkville, Australia
Biol Psychiatry 71:684-92. 2012..This study aims to determine whether adolescents who have initiated cannabis use early (i.e., before age 17 years) show premorbid structural abnormalities in the amygdala, hippocampus, orbitofrontal cortex, and anterior cingulate cortex... - Evidence and implications for early intervention in bipolar disorderMichael Berk
Department of Clinical and Biomedical Sciences, University of Melbourne, Parkville, Australia
J Ment Health 19:113-26. 2010..To review the evidence that supports early intervention in the treatment of bipolar disorder... - The influence of sulcal variability on morphometry of the human anterior cingulate and paracingulate cortexAlex Fornito
Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne, Australia
Neuroimage 33:843-54. 2006.... - Variability of the paracingulate sulcus and morphometry of the medial frontal cortex: associations with cortical thickness, surface area, volume, and sulcal depthAlex Fornito
Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne, Melbourne, Australia
Hum Brain Mapp 29:222-36. 2008.... - Anterior cingulate activation during Stroop task performance: a PET to MRI coregistration study of individual patients with schizophreniaMurat Yucel
Cognitive Neuropsychiatry Research and Academic Unit, Department of Psychiatry, Howard Florey Institute, University of Melbourne, Victoria, Australia
Am J Psychiatry 159:251-4. 2002.... - Anatomical abnormalities of the anterior cingulate and paracingulate cortex in patients with bipolar I disorderAlex Fornito
Melbourne Neuropsychiatry Centre, The University of Melbourne, Melbourne, Australia
Psychiatry Res 162:123-32. 2008..These findings suggest that bipolar disorder is associated with more pronounced changes in the PaC, and that reliance on volumetric measures alone may obscure more subtle differences... - Abnormal white matter microstructure in schizophrenia: a voxelwise analysis of axial and radial diffusivityMarc L Seal
Melbourne Neuropsychiatry Centre, The University of Melbourne, Victoria, Australia
Schizophr Res 101:106-10. 2008..This finding suggests that the loss of white matter integrity in schizophrenia is the result of demyelination and/or changes to the axonal cytoskeleton rather than gross axonal damage... - Maternal responses to adolescent positive affect are associated with adolescents' reward neuroanatomySarah Whittle
ORYGEN Research Centre, The Centre for Youth Mental Health, The University of Melbourne, Melbourne, VIC 3052, Australia
Soc Cogn Affect Neurosci 4:247-56. 2009.... - White matter microstructure in opiate addictionEmre Bora
Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne and Melbourne Health, Australia
Addict Biol 17:141-8. 2012..Together, the findings indicate that chronic OA use has widespread and diverse effects on neuronal connectivity and function... - Pituitary volume prospectively predicts internalizing symptoms in adolescenceAmy R Zipursky
Orygen Youth Health Research Centre, Centre for Youth Mental Health, University of Melbourne, Australia
J Child Psychol Psychiatry 52:315-23. 2011.... - White matter microstructure in patients with obsessive-compulsive disorderEmre Bora
Melbourne Neuropsychiatry Centre, Department of Psychiatry, University of Melbourne and Melbourne Health, Victoria, Australia
J Psychiatry Neurosci 36:42-6. 2011.... - Increased amygdala response to positive social feedback in young people with major depressive disorderChristopher G Davey
Orygen Youth Health Research Centre, The University of Melbourne, Melbourne, Australia
Biol Psychiatry 69:734-41. 2011.... - A tale of two cities: a neuroimaging investigation of Melbourne-Sydney rivalry comparing cortical thickness in healthy adultsDennis Velakoulis
Melbourne Neuropsychiatry Centre, University of Melbourne, Melbourne, Vic, Australia
Australas Psychiatry 15:67-71. 2007..We sought to identify neurobiological correlates of Melbourne-Sydney rivalry through neuroimaging measures of a key brain region involved in cognitive and emotional regulation... - Dopamine modulates neural networks involved in effort-based decision-makingSeyed M Assadi
Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne and Melbourne Health, Australia
Neurosci Biobehav Rev 33:383-93. 2009..This is apparently achieved by modulating other neurotransmission systems and by transmitting different signals via D1 vs. D2 receptor subtypes and phasic vs. tonic firing... - Neuroanatomical abnormalities in schizophrenia: a multimodal voxelwise meta-analysis and meta-regression analysisEmre Bora
Melbourne Neuropsychiatry Centre, Department of Psychiatry, University of Melbourne and Melbourne Health, Level 3, National Neuroscience Facility, Alan Gilbert Building, 161, Barry St, Carlton South, Vic, 3053, Australia
Schizophr Res 127:46-57. 2011..However, the available findings are biased towards characteristics of schizophrenia samples with poor prognosis... - Increased pituitary volume in patients with established bipolar affective disorderTsutomu Takahashi
Department of Psychiatry, Melbourne Neuropsychiatry Centre, University of Melbourne and Melbourne Health, Victoria, Australia
Prog Neuropsychopharmacol Biol Psychiatry 33:1245-9. 2009..psychotic and nonpsychotic). Pituitary volume was larger in females than in males for both groups. These results support previous neuroendocrine findings that implicate HPA axis dysfunction in the core pathophysiological process of BD... - Progressive changes in the development toward schizophrenia: studies in subjects at increased symptomatic riskStephen J Wood
Melbourne Neuropsychiatry Centre, Department of Psychiatry, University of Melbourne, Australia
Schizophr Bull 34:322-9. 2008..Active changes during transition to illness may present the potential to intervene and ameliorate these changes with potential benefit clinically... - Being liked activates primary reward and midline self-related brain regionsChristopher G Davey
Orygen Youth Health Research Centre, The University of Melbourne, Victoria, Australia
Hum Brain Mapp 31:660-8. 2010..This study demonstrates that neural response to being liked has features that are consistent with response to other rewarding events, but it has additional features that reflect its intrinsically interpersonal character... - Cognitive impairment in affective psychoses: a meta-analysisEmre Bora
Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne and Melbourne Health, Alan Gilbert Building NNF Level 3, Carlton 3053, Australia
Schizophr Bull 36:112-25. 2010..In general, the pattern of cognitive impairments in AP was similar to reported findings in euthymic patients with BD, but relatively more pronounced... - Cognitive impairment in schizophrenia and affective psychoses: implications for DSM-V criteria and beyondEmre Bora
Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne and Melbourne Health, Alan Gilbert Building NNF Level 3, Carlton 3053, Australia
Schizophr Bull 36:36-42. 2010..Given the state of current evidence, these possibilities appear to represent the most parsimonious approaches to the inclusion of cognitive deficits in the diagnostic criteria of schizophrenia and, potentially, of mood disorders... - Amygdala volumes in a sample of current depressed and remitted depressed patients and healthy controlsValentina Lorenzetti
Department of Psychiatry, The University of Melbourne, Melbourne, Australia
J Affect Disord 120:112-9. 2010..e., enlargement versus shrinkage); and (III) what the role of laterality is in amygdala volumetric alterations in MDD... - Voxelwise meta-analysis of gray matter abnormalities in bipolar disorderEmre Bora
Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne, Melbourne, Victoria, Australia
Biol Psychiatry 67:1097-105. 2010..We conducted a meta-analysis of gray matter abnormalities in bipolar disorder (BD) using voxel-based morphometry studies to help clarify the structural abnormalities underpinning this condition... - Pituitary gland volume among heroin users stabilised on substitution pharmacotherapyValentina Lorenzetti
Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne and Melbourne Health, National Neuroscience Facility, Alan Gilbert Building, 161 Barry Street, Carlton South, VIC 3053, Australia
Drug Alcohol Depend 110:164-6. 2010..These findings indicate that substitution pharmacotherapy may have differential effects on normalising HPA axis activity... - Midline brain structures in patients with current and remitted major depressionTsutomu Takahashi
Melbourne Neuropsychiatry Centre, Department of Psychiatry, University of Melbourne and Melbourne Health, Victoria, Australia
Prog Neuropsychopharmacol Biol Psychiatry 33:1058-63. 2009..Whether the AI length exhibits ongoing changes across the course of the illness remains to be determined in longitudinal studies... - Cognitive endophenotypes of bipolar disorder: a meta-analysis of neuropsychological deficits in euthymic patients and their first-degree relativesEmre Bora
Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne, Vic, Australia
J Affect Disord 113:1-20. 2009..Our aim was to delineate neuropsychological deficits related to genetic susceptibility, illness process and iatrogenic factors in bipolar disorder (BD)... - Reconciling neuroimaging and neuropathological findings in schizophrenia and bipolar disorderAlex Fornito
Faculty of Medicine, Dentistry and Health Science, Department of Psychiatry, Melbourne Neuropsychiatry Centre, The University of Melbourne, Parkville, Victoria, Australia
Curr Opin Psychiatry 22:312-9. 2009..In this study, we overview recent sMRI findings in schizophrenia and bipolar disorder and consider how they relate to neuropathological data... - Whole-brain anatomical networks: does the choice of nodes matter?Andrew Zalesky
Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne, Melbourne, Australia
Neuroimage 50:970-83. 2010..9 vs. sigma(4000)=53.6+/-2.2). These findings indicate that any comparison of network parameters across studies must be made with reference to the spatial scale of the nodal parcellation... - Corpus callosum size and shape in established bipolar affective disorderMark Walterfang
Melbourne Neuropsychiatry Centre, University of Melbourne, Melbourne, Victoria 3050, Australia
Aust N Z J Psychiatry 43:838-45. 2009..The aim of the present study was therefore to examine callosal size and shape in a well-defined group of bipolar affective disorder patients and controls... - A manual and automated MRI study of anterior cingulate and orbito-frontal cortices, and caudate nucleus in obsessive-compulsive disorder: comparison with healthy controls and patients with schizophreniaJem Riffkin
Melbourne Neuropsychiatry Centre, University of Melbourne and Sunshine Hospital, Melbourne, Victoria, Australia
Psychiatry Res 138:99-113. 2005..The findings suggest that in contrast to findings in SCZ, there are very few (if any) gross structural anomalies in OCD... - Altered corticostriatal functional connectivity in obsessive-compulsive disorderBen J Harrison
Institut d Alta Tecnologia Parc de Recerca Biomèdica de Barcelona, Centro Radiológico Computerizado Corporació Sanitària, Barcelona, Spain
Arch Gen Psychiatry 66:1189-200. 2009..quot; Although neuroimaging studies of patients have supported this network model of OCD, very few have applied measurements that are sensitive to brain connectivity features... - Early and late neurodevelopmental disturbances in schizophrenia and their functional consequencesChristos Pantelis
Cognitive Neuropsychiatry Research and Academic Unit, Sunshine Hospital, 176 Furlong Road, St Albans, 3021, Victoria, Australia
Aust N Z J Psychiatry 37:399-406. 2003..In this paper we review the timing of structural changes in schizophrenia and argue that schizophrenia is a neuro-developmental disorder with limited progressive brain changes occurring during the evolution and early phase of psychosis... - Neurobiology of schizophrenia spectrum disorders: the role of oxidative stressStephen J Wood
Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne and Melbourne Health, Melbourne, Australia
Ann Acad Med Singapore 38:396-6. 2009..We argue that a better understanding of the mechanisms and pathways underlying oxidative stress will assist in developing the therapeutic potential of this area... - Consistency and functional specialization in the default mode brain networkBen J Harrison
Institut d Alta Tecnologia Parc de Recerca Biomèdica de Barcelona, CRC Corporació Sanitària, 08003 Barcelona, Spain
Proc Natl Acad Sci U S A 105:9781-6. 2008..Mapping spontaneous and task-related brain activity will help to constrain the meaning of the default mode network. These findings are discussed in relation to recent debate on the topic of default modes of brain function... - Hippocampal and anterior cingulate morphology in subjects at ultra-high-risk for psychosis: the role of family history of psychotic illnessStephen J Wood
Melbourne Neuropsychiatry Centre, Department of Psychiatry, University of Melbourne, National Neuroscience Facility, 161 Barry Street, Carlton South VIC 3053, Australia
Schizophr Res 75:295-301. 2005..Some appear to predate the illness and may be genetic in origin, while others are associated with the onset of the disorder... - Modulation of brain resting-state networks by sad mood inductionBen J Harrison
Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne and Melbourne Health, Victoria, Australia
PLoS ONE 3:e1794. 2008..While these 'resting-state networks' may be relatively enduring phenomena, other evidence suggest that dynamic changes in their functional connectivity may also emerge depending on the brain state of subjects during scanning... - Solvent-induced leukoencephalopathy: a disorder of adolescence?Michael Takagi
Orygen Youth Health Research Centre, Centre for Youth Mental Health, University of Melbourne, Melbourne, Victoria, Australia
Subst Use Misuse 46:95-8. 2011..Longitudinal studies utilizing well-matched control samples are required to fully delineate the short- and long-term impact of volatile substance misuse on adolescent brain development... - Sex differences in the neural correlates of emotion: evidence from neuroimagingSarah Whittle
Centre for Youth Mental Health, Orygen Youth Health Research Centre, The University of Melbourne, 35 Polar Road, Parkville, Victoria 3052, Australia
Biol Psychol 87:319-33. 2011..Importantly, results suggest that sex differences should not be ignored in research investigating the neurobiology of emotion... - The role of executive control in human drug addictionRobert Hester
Department of Psychology, University of Melbourne, Melbourne, Vic, 3010, Australia
Curr Top Behav Neurosci 3:301-18. 2010..Finally, we consider the potential impact of early drug use on the developing adolescent brain, and discuss research examining premorbid executive control impairments in drug-naïve "at-risk" populations... - Structural brain imaging evidence for multiple pathological processes at different stages of brain development in schizophreniaChristos Pantelis
Melbourne Neuropsychiatry Centre, Department of Psychiatry, University of Melbourne, Royal Melbourne Hospital, Sunshine Hospital, Victoria
Schizophr Bull 31:672-96. 2005.... - Task-induced deactivation of midline cortical regions in schizophrenia assessed with fMRIBen J Harrison
Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne, Australia
Schizophr Res 91:82-6. 2007..The nature of these associations suggests a complex interchange between cognitive and emotional influences on the resting-state activity of these prefrontal 'default mode' regions in schizophrenia... - Adolescent obsessive compulsive disorder heralding chorea-acanthocytosisMark Walterfang
Melbourne Neuropsychiatry Centre, University of Melbourne, Melbourne, Australia
Mov Disord 23:422-5. 2008.... - Genetic influences on cost-efficient organization of human cortical functional networksAlex Fornito
Brain Mapping Unit, Behavioural and Clinical Neurosciences Institute, University of Cambridge, Cambridge CB2 3EB, United Kingdom
J Neurosci 31:3261-70. 2011.... - Cognitive functioning in schizophrenia, schizoaffective disorder and affective psychoses: meta-analytic studyEmre Bora
Melbourne Neuropsychiatry Centre, Alan Gilbert Building, National Neuroscience Facility, Level 3, Victoria 3053, Australia
Br J Psychiatry 195:475-82. 2009..Cognitive functioning in affective psychosis and schizoaffective disorder is much less studied compared with schizophrenia... - Individual differences in anterior cingulate/paracingulate morphology are related to executive functions in healthy malesAlexander Fornito
Melbourne Neuropsychiatry Centre, Department of Psychiatry, The University of Melbourne, Sunshine Hospital, 176 Furlong Road, St Albans, Victoria 3021, Australia
Cereb Cortex 14:424-31. 2004..It therefore appears that normal variations in brain morphology are associated with individual differences in cognitive abilities... - Neurobiology of human affiliative behaviour: implications for psychiatric disordersEmre Bora
Melbourne Neuropsychiatry Centre, The University of Melbourne and Melbourne Health, Vic, Australia
Curr Opin Psychiatry 22:320-5. 2009..This article aims to review recent brain imaging and neuropeptide studies that investigated human affiliation... - Morphology of the anterior cingulate cortex in young men at ultra-high risk of developing a psychotic illnessMurat Yucel
Department of Psychiatry, University of Melbourne, Parkville, Victoria, Australia
Br J Psychiatry 182:518-24. 2003..The anterior cingulate cortex (ACC) is consistently implicated in the pathophysiology of schizophrenia, and our own work has identified morphological anomalies in the ACC of people with this disorder...