Research Topics
| D Y YuSummaryAffiliation: University of Western Australia Country: Australia Publications
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Detail Information
Publications
Oxygen distribution and consumption within the retina in vascularised and avascular retinas and in animal models of retinal diseaseD Y Yu
Centre for Ophthalmology and Visual Science, Lions Eye Institute, The University of Western Australia, 2 Verdun Street, WA 6009, Nedlands, Australia
Prog Retin Eye Res 20:175-208. 2001..We examine the effect of acute and chronic occlusion of the retinal vasculature, and explore the feasibility of meeting the oxygen needs of the ischemic retina from the choroid. (ABSTRACT TRUNCATED)..
Acetylcholine-induced vasodilation of isolated pulpal arteriolesC Y Yu
School of Dentistry, The University of Western Australia, Perth, Australia
J Dent Res 80:1995-9. 2001..Analysis of these data suggests that, in the pig, the acetylcholine-induced vasodilation of incisor pulpal arterioles is endothelium-dependent and mediated by muscarinic receptors...
Quantification of retinal oxygen consumption changes from preretinal oxygen transientsS J Cringle
Lions Eye Institute, The University of Western Australia, Nedlands, Australia
Aust N Z J Ophthalmol 26:S71-3. 1998..In the avascular retina of the guinea-pig all the oxygen supply is from the choroid. Under these circumstances we had proposed, on theoretical grounds, that a change in retinal oxygen consumption would modulate the preretinal oxygen level...
Comparison of the vasoactive effects of the docosanoid unoprostone and selected prostanoids on isolated perfused retinal arteriolesD Y Yu
Centre for Ophthalmology and Visual Science, The University of Western Australia, Perth
Invest Ophthalmol Vis Sci 42:1499-504. 2001..To compare the vasoactive properties of the docosanoid unoprostone, its free acid, and different members of the prostanoid family on isolated perfused pig retinal arterioles to assess their potential to modulate retinal blood flow...
Pathogenesis and intervention strategies in diabetic retinopathyD Y Yu
Physiology and Pharmacology Centre, Centre for Ophthalmology and Visual Science, The University of Western Australia, Nedlands, Australia
Clin Experiment Ophthalmol 29:164-6. 2001..It is concluded that improved treatment outcomes may ensue if the therapy is targeted at the appropriate tissue at specific stages of the disease...
Light and choroidal PO2 modulation of intraretinal oxygen levels in an avascular retinaS J Cringle
Centre for Ophthalmology and Visual Science, The University of Western Australia, Nedlands, Perth
Invest Ophthalmol Vis Sci 40:2307-13. 1999..This condition prevails in avascular retinas and in vascularized retinas suffering vascular occlusion...
Overview of studies on metabolic and vascular regulatory changes in early diabetic retinopathyV A Alder
Lions Eye Institute and Centre for Ophthalmology and Visual Science, University of Western Australia, Nedlands, Australia
Aust N Z J Ophthalmol 26:141-8. 1998..The review raises the question of whether choroid dysfunction is also a feature of diabetic retinopathy...
A pilot study of in vivo venous pressures in the pig retinal circulationW H Westlake
Centre for Ophthalmology and Visual Sciences, Lions Eye Institute, University of Western Australia, Nedlands, Australia
Clin Experiment Ophthalmol 29:167-70. 2001..92). The results are compatible with the Starling resistor theory of venous outflow from the eye...
An in vivo and in vitro comparison of the effects of vasoactive mediators on pulpal blood vessels in rat incisorsC Y Yu
School of Dentistry, The University of Western Australia, 17 Monash Avenue, WA 6009, Nedlands, Australia
Arch Oral Biol 47:723-32. 2002....
Intraretinal oxygen levels before and after photoreceptor loss in the RCS ratD Y Yu
Centre for Ophthalmology and Visual Science, The University of Western Australia, Perth, Australia
Invest Ophthalmol Vis Sci 41:3999-4006. 2000..To measure the intraretinal oxygen environment at different stages in the Royal College of Surgeons (RCS) rat model of retinal degeneration to determine whether changes in oxygen level are an important aspect of the disease...
Comparison of hematologic parameters in normal and streptozotocin-induced diabetic ratsV A Alder
Lions Eye Institute, Nedlands, Western Australia
Lab Anim Sci 42:170-3. 1992..This compensatory mechanism also occurs in some stages of human diabetes...
Diabetic retinopathy: early functional changesV A Alder
Lions Eye Institute, Nedlands, Western Australia, Australia
Clin Exp Pharmacol Physiol 24:785-8. 1997....
Axotomy-induced cytoskeleton changes in unmyelinated mammalian central nervous system axonsC Balaratnasingam
Centre for Ophthalmology and Visual Science, The University of Western Australia, 2 Verdun Street, Nedlands, Perth, Australia
Neuroscience 177:269-82. 2011..The findings of this report have relevance to understanding pathogenic mechanisms underlying neuro-degeneration in the CNS...
Robotic ocular ultramicrosurgeryD Y Yu
Lions Eye Institute, The University of Western Australia, Perth, Australia
Aust N Z J Ophthalmol 26:S6-8. 1998..The present paper describes the design principles used in the development of a robotic ocular ultramicrosurgical system and the results from preliminary animal trials...
Culture and characterization of smooth muscle cells from porcine retinal microvesselsB C Mortimer
Lions Eye Institute and Centre for Ophthalmology and Visual Science, The University of Western Australia, Nedlands, Australia
Aust N Z J Ophthalmol 26:S80-3. 1998..To establish long-term cultures of retinal vascular smooth muscle cells for future studies of their functions under normal and diseased conditions...
Tetrahydrobiopterin reverses the impairment of acetylcholine-induced vasodilatation in diabetic ocular microvasculatureP K Yu
Centre for Ophthalmology and Visual Science, The University of Western Australia, Perth
J Ocul Pharmacol Ther 17:123-9. 2001..5 +/- 0.2 weeks postinduction. Our result suggests that a decreased level of tetrahydrobiopterin in the eyes of the streptozotocin-induced diabetic rats may be responsible for the ocular vascular endothelium dysfunction...
Laser-induced chorioretinal venous anastomosis for nonischemic central retinal vein occlusion: evaluation of the complications and their risk factorsI L McAllister
Lions Eye Institute, Nedlands, Western Australia
Am J Ophthalmol 126:219-29. 1998..To evaluate the complications of laser-induced chorioretinal venous anastomosis in nonischemic central retinal vein occlusion (CRVO) and to identify the associated risks...
Relaxation effects of diltiazem, verapamil, and tolazoline on isolated cat ophthalmociliary arteryD Y Yu
Lions Eye Institute, University of Western Australia, Nedlands
Exp Eye Res 55:757-66. 1992....
Oxygen distribution and consumption in rat lower incisor pulpC Y Yu
School of Dentistry, The University of Western Australia, 17 Monash Avenue, Nedlands, 6009, WA, Australia
Arch Oral Biol 47:529-36. 2002..The zone of high oxygen consumption was 68.7 micro m+/-6.9 micro m (n=24) thick. It is concluded that pulpal oxygen distribution is heterogeneous and that the odontoblast could be a major oxygen consumer within the rat incisor pulp...
The association between retinal vein ophthalmodynamometric force change and optic disc excavationW H Morgan
Department of Physiology and Pharmacology, Lions Eye Institute, Nedlands, Western Australia, Australia
Br J Ophthalmol 93:594-6. 2009..We aimed to assess whether a change in ODF provides additional prognostic information...
Wearing swimming goggles can elevate intraocular pressureW H Morgan
Department of Physiology and Pharmacology, Centre for Ophthalmology and Visual Science, Lions Eye Institute, University of Western Australia, Western Australia, Australia
Br J Ophthalmol 92:1218-21. 2008..To examine the acute effects of wearing swimming goggles upon intraocular pressure (IOP)...
Agonist-induced vasoactive responses in isolated perfused porcine dental pulpal arteriolesC Y Yu
School of Dentistry, The University of Western Australia, 179 Wellington Street, WA 6000, Perth, Australia
Arch Oral Biol 47:99-107. 2002..The isolated perfused pulpal arteriole preparation may prove valuable in understanding local control mechanisms of pulpal microcirculation...
The type II peroxiredoxin gene family of the mouse: molecular structure, expression and evolutionM J Lim
Molecular, Cellular Biology Research Division, Korea Research Institute of Bioscience, Biotechnology, PO Box 115, Yusong, Taejon 305 600, South Korea
Gene 216:197-205. 1998..These results strongly suggest that only the Prx II-1 gene might be relevant for studying the function of the Prx II gene in the murine system...
Characterization of the murine gene encoding 1-Cys peroxiredoxin and identification of highly homologous genesT H Lee
Korea Research Institute of Bioscience and Biotechnology, PO Box 115, Yusong, Taejon 305 600, South Korea
Gene 234:337-44. 1999..These results suggest that only the 1-Cys Prx gene might be relevant for studying the function of the 1-Cys Prx in the murine system...
Characterization of mouse peroxiredoxin I genomic DNA and its expressionT H Lee
Korea Research Institute of Bioscience and Biotechnology, P O Box 115, Yusong, Taejon, South Korea
Gene 239:243-50. 1999..e. the Prx I gene was well conserved in human and mice via its anti-oxidant activity...
