D Y Yu

Summary

Affiliation: University of Western Australia
Country: Australia

Publications

  1. ncbi request reprint Oxygen distribution and consumption within the retina in vascularised and avascular retinas and in animal models of retinal disease
    D Y Yu
    Centre for Ophthalmology and Visual Science, Lions Eye Institute, The University of Western Australia, 2 Verdun Street, WA 6009, Nedlands, Australia
    Prog Retin Eye Res 20:175-208. 2001
  2. ncbi request reprint Acetylcholine-induced vasodilation of isolated pulpal arterioles
    C Y Yu
    School of Dentistry, The University of Western Australia, Perth, Australia
    J Dent Res 80:1995-9. 2001
  3. ncbi request reprint Quantification of retinal oxygen consumption changes from preretinal oxygen transients
    S J Cringle
    Lions Eye Institute, The University of Western Australia, Nedlands, Australia
    Aust N Z J Ophthalmol 26:S71-3. 1998
  4. ncbi request reprint Confocal laser Doppler flowmeter measurements in a controlled flow environment in an isolated perfused eye
    R Townsend
    Centre for Ophthalmology and Visual Science, University of Western Australia, Nedlands, Perth, Australia
    Exp Eye Res 82:65-73. 2006
  5. ncbi request reprint Light and choroidal PO2 modulation of intraretinal oxygen levels in an avascular retina
    S J Cringle
    Centre for Ophthalmology and Visual Science, The University of Western Australia, Nedlands, Perth
    Invest Ophthalmol Vis Sci 40:2307-13. 1999
  6. ncbi request reprint Comparison of the vasoactive effects of the docosanoid unoprostone and selected prostanoids on isolated perfused retinal arterioles
    D Y Yu
    Centre for Ophthalmology and Visual Science, The University of Western Australia, Perth
    Invest Ophthalmol Vis Sci 42:1499-504. 2001
  7. ncbi request reprint Pathogenesis and intervention strategies in diabetic retinopathy
    D Y Yu
    Physiology and Pharmacology Centre, Centre for Ophthalmology and Visual Science, The University of Western Australia, Nedlands, Australia
    Clin Experiment Ophthalmol 29:164-6. 2001
  8. ncbi request reprint Overview of studies on metabolic and vascular regulatory changes in early diabetic retinopathy
    V A Alder
    Lions Eye Institute and Centre for Ophthalmology and Visual Science, University of Western Australia, Nedlands, Australia
    Aust N Z J Ophthalmol 26:141-8. 1998
  9. ncbi request reprint A pilot study of in vivo venous pressures in the pig retinal circulation
    W H Westlake
    Centre for Ophthalmology and Visual Sciences, Lions Eye Institute, University of Western Australia, Nedlands, Australia
    Clin Experiment Ophthalmol 29:167-70. 2001
  10. ncbi request reprint An in vivo and in vitro comparison of the effects of vasoactive mediators on pulpal blood vessels in rat incisors
    C Y Yu
    School of Dentistry, The University of Western Australia, 17 Monash Avenue, WA 6009, Nedlands, Australia
    Arch Oral Biol 47:723-32. 2002

Collaborators

Detail Information

Publications26

  1. ncbi request reprint Oxygen distribution and consumption within the retina in vascularised and avascular retinas and in animal models of retinal disease
    D Y Yu
    Centre for Ophthalmology and Visual Science, Lions Eye Institute, The University of Western Australia, 2 Verdun Street, WA 6009, Nedlands, Australia
    Prog Retin Eye Res 20:175-208. 2001
    ..We examine the effect of acute and chronic occlusion of the retinal vasculature, and explore the feasibility of meeting the oxygen needs of the ischemic retina from the choroid. (ABSTRACT TRUNCATED)..
  2. ncbi request reprint Acetylcholine-induced vasodilation of isolated pulpal arterioles
    C Y Yu
    School of Dentistry, The University of Western Australia, Perth, Australia
    J Dent Res 80:1995-9. 2001
    ..Analysis of these data suggests that, in the pig, the acetylcholine-induced vasodilation of incisor pulpal arterioles is endothelium-dependent and mediated by muscarinic receptors...
  3. ncbi request reprint Quantification of retinal oxygen consumption changes from preretinal oxygen transients
    S J Cringle
    Lions Eye Institute, The University of Western Australia, Nedlands, Australia
    Aust N Z J Ophthalmol 26:S71-3. 1998
    ..In the avascular retina of the guinea-pig all the oxygen supply is from the choroid. Under these circumstances we had proposed, on theoretical grounds, that a change in retinal oxygen consumption would modulate the preretinal oxygen level...
  4. ncbi request reprint Confocal laser Doppler flowmeter measurements in a controlled flow environment in an isolated perfused eye
    R Townsend
    Centre for Ophthalmology and Visual Science, University of Western Australia, Nedlands, Perth, Australia
    Exp Eye Res 82:65-73. 2006
    ..The major arteries and veins provide the strongest signal and greatest signal to noise ratio. However, the retinal arterioles produce an HRF signal that is more linear over a wider range of perfusate flow rates...
  5. ncbi request reprint Light and choroidal PO2 modulation of intraretinal oxygen levels in an avascular retina
    S J Cringle
    Centre for Ophthalmology and Visual Science, The University of Western Australia, Nedlands, Perth
    Invest Ophthalmol Vis Sci 40:2307-13. 1999
    ..This condition prevails in avascular retinas and in vascularized retinas suffering vascular occlusion...
  6. ncbi request reprint Comparison of the vasoactive effects of the docosanoid unoprostone and selected prostanoids on isolated perfused retinal arterioles
    D Y Yu
    Centre for Ophthalmology and Visual Science, The University of Western Australia, Perth
    Invest Ophthalmol Vis Sci 42:1499-504. 2001
    ..To compare the vasoactive properties of the docosanoid unoprostone, its free acid, and different members of the prostanoid family on isolated perfused pig retinal arterioles to assess their potential to modulate retinal blood flow...
  7. ncbi request reprint Pathogenesis and intervention strategies in diabetic retinopathy
    D Y Yu
    Physiology and Pharmacology Centre, Centre for Ophthalmology and Visual Science, The University of Western Australia, Nedlands, Australia
    Clin Experiment Ophthalmol 29:164-6. 2001
    ..It is concluded that improved treatment outcomes may ensue if the therapy is targeted at the appropriate tissue at specific stages of the disease...
  8. ncbi request reprint Overview of studies on metabolic and vascular regulatory changes in early diabetic retinopathy
    V A Alder
    Lions Eye Institute and Centre for Ophthalmology and Visual Science, University of Western Australia, Nedlands, Australia
    Aust N Z J Ophthalmol 26:141-8. 1998
    ..The review raises the question of whether choroid dysfunction is also a feature of diabetic retinopathy...
  9. ncbi request reprint A pilot study of in vivo venous pressures in the pig retinal circulation
    W H Westlake
    Centre for Ophthalmology and Visual Sciences, Lions Eye Institute, University of Western Australia, Nedlands, Australia
    Clin Experiment Ophthalmol 29:167-70. 2001
    ..92). The results are compatible with the Starling resistor theory of venous outflow from the eye...
  10. ncbi request reprint An in vivo and in vitro comparison of the effects of vasoactive mediators on pulpal blood vessels in rat incisors
    C Y Yu
    School of Dentistry, The University of Western Australia, 17 Monash Avenue, WA 6009, Nedlands, Australia
    Arch Oral Biol 47:723-32. 2002
    ....
  11. ncbi request reprint Comparison of hematologic parameters in normal and streptozotocin-induced diabetic rats
    V A Alder
    Lions Eye Institute, Nedlands, Western Australia
    Lab Anim Sci 42:170-3. 1992
    ..This compensatory mechanism also occurs in some stages of human diabetes...
  12. ncbi request reprint Intraretinal oxygen levels before and after photoreceptor loss in the RCS rat
    D Y Yu
    Centre for Ophthalmology and Visual Science, The University of Western Australia, Perth, Australia
    Invest Ophthalmol Vis Sci 41:3999-4006. 2000
    ..To measure the intraretinal oxygen environment at different stages in the Royal College of Surgeons (RCS) rat model of retinal degeneration to determine whether changes in oxygen level are an important aspect of the disease...
  13. ncbi request reprint Diabetic retinopathy: early functional changes
    V A Alder
    Lions Eye Institute, Nedlands, Western Australia, Australia
    Clin Exp Pharmacol Physiol 24:785-8. 1997
    ....
  14. ncbi request reprint Robotic ocular ultramicrosurgery
    D Y Yu
    Lions Eye Institute, The University of Western Australia, Perth, Australia
    Aust N Z J Ophthalmol 26:S6-8. 1998
    ..The present paper describes the design principles used in the development of a robotic ocular ultramicrosurgical system and the results from preliminary animal trials...
  15. ncbi request reprint Culture and characterization of smooth muscle cells from porcine retinal microvessels
    B C Mortimer
    Lions Eye Institute and Centre for Ophthalmology and Visual Science, The University of Western Australia, Nedlands, Australia
    Aust N Z J Ophthalmol 26:S80-3. 1998
    ..To establish long-term cultures of retinal vascular smooth muscle cells for future studies of their functions under normal and diseased conditions...
  16. ncbi request reprint Tetrahydrobiopterin reverses the impairment of acetylcholine-induced vasodilatation in diabetic ocular microvasculature
    P K Yu
    Centre for Ophthalmology and Visual Science, The University of Western Australia, Perth
    J Ocul Pharmacol Ther 17:123-9. 2001
    ..5 +/- 0.2 weeks postinduction. Our result suggests that a decreased level of tetrahydrobiopterin in the eyes of the streptozotocin-induced diabetic rats may be responsible for the ocular vascular endothelium dysfunction...
  17. doi request reprint Axotomy-induced cytoskeleton changes in unmyelinated mammalian central nervous system axons
    C Balaratnasingam
    Centre for Ophthalmology and Visual Science, The University of Western Australia, 2 Verdun Street, Nedlands, Perth, Australia
    Neuroscience 177:269-82. 2011
    ..The findings of this report have relevance to understanding pathogenic mechanisms underlying neuro-degeneration in the CNS...
  18. ncbi request reprint Laser-induced chorioretinal venous anastomosis for nonischemic central retinal vein occlusion: evaluation of the complications and their risk factors
    I L McAllister
    Lions Eye Institute, Nedlands, Western Australia
    Am J Ophthalmol 126:219-29. 1998
    ..To evaluate the complications of laser-induced chorioretinal venous anastomosis in nonischemic central retinal vein occlusion (CRVO) and to identify the associated risks...
  19. ncbi request reprint Relaxation effects of diltiazem, verapamil, and tolazoline on isolated cat ophthalmociliary artery
    D Y Yu
    Lions Eye Institute, University of Western Australia, Nedlands
    Exp Eye Res 55:757-66. 1992
    ....
  20. ncbi request reprint Oxygen distribution and consumption in rat lower incisor pulp
    C Y Yu
    School of Dentistry, The University of Western Australia, 17 Monash Avenue, Nedlands, 6009, WA, Australia
    Arch Oral Biol 47:529-36. 2002
    ..The zone of high oxygen consumption was 68.7 micro m+/-6.9 micro m (n=24) thick. It is concluded that pulpal oxygen distribution is heterogeneous and that the odontoblast could be a major oxygen consumer within the rat incisor pulp...
  21. doi request reprint Wearing swimming goggles can elevate intraocular pressure
    W H Morgan
    Department of Physiology and Pharmacology, Centre for Ophthalmology and Visual Science, Lions Eye Institute, University of Western Australia, Western Australia, Australia
    Br J Ophthalmol 92:1218-21. 2008
    ..To examine the acute effects of wearing swimming goggles upon intraocular pressure (IOP)...
  22. doi request reprint The association between retinal vein ophthalmodynamometric force change and optic disc excavation
    W H Morgan
    Department of Physiology and Pharmacology, Lions Eye Institute, Nedlands, Western Australia, Australia
    Br J Ophthalmol 93:594-6. 2009
    ..We aimed to assess whether a change in ODF provides additional prognostic information...
  23. ncbi request reprint Agonist-induced vasoactive responses in isolated perfused porcine dental pulpal arterioles
    C Y Yu
    School of Dentistry, The University of Western Australia, 179 Wellington Street, WA 6000, Perth, Australia
    Arch Oral Biol 47:99-107. 2002
    ..The isolated perfused pulpal arteriole preparation may prove valuable in understanding local control mechanisms of pulpal microcirculation...
  24. ncbi request reprint The type II peroxiredoxin gene family of the mouse: molecular structure, expression and evolution
    M J Lim
    Molecular, Cellular Biology Research Division, Korea Research Institute of Bioscience, Biotechnology, PO Box 115, Yusong, Taejon 305 600, South Korea
    Gene 216:197-205. 1998
    ..These results strongly suggest that only the Prx II-1 gene might be relevant for studying the function of the Prx II gene in the murine system...
  25. ncbi request reprint Characterization of the murine gene encoding 1-Cys peroxiredoxin and identification of highly homologous genes
    T H Lee
    Korea Research Institute of Bioscience and Biotechnology, PO Box 115, Yusong, Taejon 305 600, South Korea
    Gene 234:337-44. 1999
    ..These results suggest that only the 1-Cys Prx gene might be relevant for studying the function of the 1-Cys Prx in the murine system...
  26. ncbi request reprint Characterization of mouse peroxiredoxin I genomic DNA and its expression
    T H Lee
    Korea Research Institute of Bioscience and Biotechnology, P O Box 115, Yusong, Taejon, South Korea
    Gene 239:243-50. 1999
    ..e. the Prx I gene was well conserved in human and mice via its anti-oxidant activity...