N D Yeomans

Summary

Affiliation: University of Western Sydney
Country: Australia

Publications

  1. pmc Maintenance treatment with esomeprazole following initial relief of non-steroidal anti-inflammatory drug-associated upper gastrointestinal symptoms: the NASA2 and SPACE2 studies
    Christopher J Hawkey
    Institute of Clinical Research, Trials Unit, Wolfson Digestive Diseases Centre, University Hospital, Derby Road, Nottingham, NG7 2UH, UK
    Arthritis Res Ther 9:R17. 2007
  2. pmc Is ranitidine therapy sufficient for healing peptic ulcers associated with non-steroidal anti-inflammatory drug use?
    N D Yeomans
    School of Medicine, University of Western Sydney, NSW, Australia
    Int J Clin Pract 60:1401-7. 2006
  3. ncbi request reprint Prevalence and incidence of gastroduodenal ulcers during treatment with vascular protective doses of aspirin
    N D Yeomans
    Western Hospital, Department of Medicine, University of Melbourne, Melbourne, and University of Western Sydney, Sydney, Australia
    Aliment Pharmacol Ther 22:795-801. 2005
  4. doi request reprint Systematic review: ulcer definition in NSAID ulcer prevention trials
    N D Yeomans
    School of Medicine, University of Western Sydney, Sydney, NSW, Australia
    Aliment Pharmacol Ther 27:465-72. 2008
  5. doi request reprint Reducing the risk of gastroduodenal ulcers with a fixed combination of esomeprazole and low-dose acetyl salicylic acid
    Neville D Yeomans
    School of Medicine, University of Western Sydney, Locked Bag 1797, Penrith South, NSW 2751, Australia
    Expert Rev Gastroenterol Hepatol 5:447-55. 2011
  6. doi request reprint Gastroduodenal toxicity of low-dose acetylsalicylic acid: a comparison with non-steroidal anti-inflammatory drugs
    Neville D Yeomans
    School of Medicine, University of Western Sydney, Penrith South DC, NSW 1797, Australia
    Curr Med Res Opin 25:2785-93. 2009
  7. doi request reprint Overview of 50 years' progress in upper gastrointestinal diseases
    Neville D Yeomans
    School of Medicine, University of Western Sydney, Penrith South DC, New South Wales, Australia
    J Gastroenterol Hepatol 24:S2-4. 2009
  8. doi request reprint Aspirin: old drug, new uses and challenges
    Neville D Yeomans
    School of Medicine, University of Western Sydney, Sydney, New South Wales, Australia
    J Gastroenterol Hepatol 26:426-31. 2011
  9. doi request reprint The ulcer sleuths: The search for the cause of peptic ulcers
    Neville D Yeomans
    University of Western Sydney, Sydney, Australia
    J Gastroenterol Hepatol 26:35-41. 2011
  10. doi request reprint Predictors of gastroduodenal erosions in patients taking low-dose aspirin
    J Hart
    Royal North Shore Hospital, St Leonards, Sydney, NSW, Australia
    Aliment Pharmacol Ther 31:143-9. 2010

Detail Information

Publications19

  1. pmc Maintenance treatment with esomeprazole following initial relief of non-steroidal anti-inflammatory drug-associated upper gastrointestinal symptoms: the NASA2 and SPACE2 studies
    Christopher J Hawkey
    Institute of Clinical Research, Trials Unit, Wolfson Digestive Diseases Centre, University Hospital, Derby Road, Nottingham, NG7 2UH, UK
    Arthritis Res Ther 9:R17. 2007
    ..The frequency of adverse events was similar in the three groups. Esomeprazole maintains relief of NSAID-associated upper GI symptoms in patients taking continuous NSAIDs, including selective COX-2 inhibitors...
  2. pmc Is ranitidine therapy sufficient for healing peptic ulcers associated with non-steroidal anti-inflammatory drug use?
    N D Yeomans
    School of Medicine, University of Western Sydney, NSW, Australia
    Int J Clin Pract 60:1401-7. 2006
    ..81% for ranitidine, p < 0.05) and 88% for omeprazole 40 mg (p = 0.17 vs. ranitidine). NSAID-associated GU are more likely to heal when patients receive concomitant treatment with a PPI rather than ranitidine...
  3. ncbi request reprint Prevalence and incidence of gastroduodenal ulcers during treatment with vascular protective doses of aspirin
    N D Yeomans
    Western Hospital, Department of Medicine, University of Melbourne, Melbourne, and University of Western Sydney, Sydney, Australia
    Aliment Pharmacol Ther 22:795-801. 2005
    ..Aspirin is valuable for preventing vascular events, but information about ulcer frequency is necessary to inform risk-benefit decisions in individual patients...
  4. doi request reprint Systematic review: ulcer definition in NSAID ulcer prevention trials
    N D Yeomans
    School of Medicine, University of Western Sydney, Sydney, NSW, Australia
    Aliment Pharmacol Ther 27:465-72. 2008
    ..In clinical trials of peptic ulcer prevention, the most appropriate definition of an ulcer remains challenging...
  5. doi request reprint Reducing the risk of gastroduodenal ulcers with a fixed combination of esomeprazole and low-dose acetyl salicylic acid
    Neville D Yeomans
    School of Medicine, University of Western Sydney, Locked Bag 1797, Penrith South, NSW 2751, Australia
    Expert Rev Gastroenterol Hepatol 5:447-55. 2011
    ..This article reviews the pharmacology of the component agents and the evidence for efficacy of the combination of esomeprazole and low-dose ASA...
  6. doi request reprint Gastroduodenal toxicity of low-dose acetylsalicylic acid: a comparison with non-steroidal anti-inflammatory drugs
    Neville D Yeomans
    School of Medicine, University of Western Sydney, Penrith South DC, NSW 1797, Australia
    Curr Med Res Opin 25:2785-93. 2009
    ..This was a narrative, descriptive review, rather than a formal systematic review...
  7. doi request reprint Overview of 50 years' progress in upper gastrointestinal diseases
    Neville D Yeomans
    School of Medicine, University of Western Sydney, Penrith South DC, New South Wales, Australia
    J Gastroenterol Hepatol 24:S2-4. 2009
    ..The story of the development of the histamine H(2)-receptor antagonists and the proton pump inhibitors is also outlined...
  8. doi request reprint Aspirin: old drug, new uses and challenges
    Neville D Yeomans
    School of Medicine, University of Western Sydney, Sydney, New South Wales, Australia
    J Gastroenterol Hepatol 26:426-31. 2011
    ..Strategies that can be used to reduce these risks include using the lowest effective aspirin dose and co-prescribing acid suppressants...
  9. doi request reprint The ulcer sleuths: The search for the cause of peptic ulcers
    Neville D Yeomans
    University of Western Sydney, Sydney, Australia
    J Gastroenterol Hepatol 26:35-41. 2011
    ..Understanding the mechanism of the first, and the discovery and demonstration of Koch's postulates for the second, have been instrumental in the award of two Nobel prizes...
  10. doi request reprint Predictors of gastroduodenal erosions in patients taking low-dose aspirin
    J Hart
    Royal North Shore Hospital, St Leonards, Sydney, NSW, Australia
    Aliment Pharmacol Ther 31:143-9. 2010
    ..Gastroduodenal ulcers are common in patients taking low-dose aspirin. However, the factors predisposing to mucosal erosions, the precursor lesions, are not well known...
  11. ncbi request reprint Trefoil peptides are early markers of gastrointestinal maturation in the rat
    M Familari
    The University of Melbourne, Department of Medicine, Western Hospital, Footscray, Australia
    Int J Dev Biol 42:783-9. 1998
    ..The time course of their expression, well before the mucus cell type is specified, suggests a potential role in epithelial cell differentiation...
  12. ncbi request reprint The nonsteroidal anti-inflammatory drugs controversy
    N D Yeomans
    Department of Medicine, University of Melbourne, Western Hospital, Melbourne, Australia
    Gastroenterol Clin North Am 29:791-805. 2000
    ..Possibilities include greater efficacy of antisecretory agents, a smaller inhibition of prostaglandin production, and a blunted apoptotic response in patients who are infected with H. pylori and take NSAIDs...
  13. ncbi request reprint Randomized trial of omeprazole and metronidazole with amoxycillin or clarithromycin for Helicobacter pylori eradication, in a region of high primary metronidazole resistance: the HERO study
    P H Katelaris
    Gastroenterology Unit, Concord Hospital, Sydney, Australia
    Aliment Pharmacol Ther 14:751-8. 2000
    ..The efficacy of omeprazole-based eradication therapies has been determined mostly in populations with low to moderate prevalence of metronidazole resistant Helicobacter pylori, yet resistance is high in many regions...
  14. ncbi request reprint Augmented gp130-mediated cytokine signalling accompanies human gastric cancer progression
    C B Jackson
    Gastrointestinal Cancer Lab, Department of Medicine, The University of Melbourne at Western Hospital, Footscray, 3011, Melbourne, Australia
    J Pathol 213:140-51. 2007
    ..IL-11 expression is associated with adenocarcinoma development, but not gastritic lesions, and we identify a novel mechanism for IL-11 as a potent inducer of proliferation in the human gastric cancer setting...
  15. ncbi request reprint Spatio-temporal expression of trefoil peptide following severe gastric ulceration in the rat implicates it in late-stage repair processes
    M Ulaganathan
    Department of Medicine, University of Melbourne at Western Hospital, Footscray, Victoria, Australia
    J Gastroenterol Hepatol 16:506-12. 2001
    ..The role of TFF1 in gastric mucosal repair was examined by analysis of the spatio-temporal expression of TFF1 following gastric ulceration in the rat...
  16. ncbi request reprint Impact of cyclooxygenase-2 inhibitors: are they fulfilling their promises?
    N D Yeomans
    Intern Med J 34:145-7. 2004
  17. pmc Influence of sex and Helicobacter pylori on development and healing of gastroduodenal lesions in non-steroidal anti-inflammatory drug users
    C J Hawkey
    Division of Gastroenterology, University Hospital Nottingham, Queen s Medical Centre, Nottingham, UK
    Gut 51:344-50. 2002
    ..Factors predisposing to endoscopic ulcer formation or healing with non-steroidal anti-inflammatory drugs (NSAIDs) have not been well defined...
  18. pmc Relative contribution of mucosal injury and Helicobacter pylori in the development of gastroduodenal lesions in patients taking non-steroidal anti-inflammatory drugs
    C J Hawkey
    Division of Gastroenterology, University Hospital, Queen s Medical Centre, Nottingham, UK
    Gut 51:336-43. 2002
    ..Whether this is due to Helicobacter pylori infection or to reactivation of the original lesion is unclear...
  19. ncbi request reprint Efficacy of esomeprazole for resolution of symptoms of heartburn and acid regurgitation in continuous users of non-steroidal anti-inflammatory drugs
    C J Hawkey
    Institute of Clinical Research Trials Unit, University Hospital, Nottingham, UK
    Aliment Pharmacol Ther 25:813-21. 2007
    ..The use of non-steroidal anti-inflammatory drugs (NSAIDs) is often associated with upper gastrointestinal symptoms such as heartburn and acid regurgitation...