Adele Woodhouse

Summary

Affiliation: University of Tasmania
Country: Australia

Publications

  1. ncbi request reprint Vaccination strategies for Alzheimer's disease: A new hope?
    Adele Woodhouse
    School of Medicine, NeuroRepair Group, University of Tasmania, Hobart, Tasmania, Australia
    Drugs Aging 24:107-19. 2007
  2. ncbi request reprint Cytoplasmic cytochrome c immunolabelling in dystrophic neurites in Alzheimer's disease
    Adele Woodhouse
    NeuroRepair Group, School of Medicine, University of Tasmania, Private Bag 29, Hobart, TAS, 7001 Australia
    Acta Neuropathol 112:429-37. 2006
  3. ncbi request reprint Dystrophic neurites in TgCRND8 and Tg2576 mice mimic human pathological brain aging
    Adele Woodhouse
    NeuroRepair Group, Menzies Research Institute, 43 Collins Street, Hobart, 7001 Tasmania, Australia
    Neurobiol Aging 30:864-74. 2009
  4. doi request reprint Cytoskeletal alterations differentiate presenilin-1 and sporadic Alzheimer's disease
    Adele Woodhouse
    Wicking Dementia Research and Education Centre and NeuroRepair Group, Menzies Research Institute, Private Bag 29, Hobart, TAS, 7001, Australia
    Acta Neuropathol 117:19-29. 2009
  5. ncbi request reprint No difference in expression of apoptosis-related proteins and apoptotic morphology in control, pathologically aged and Alzheimer's disease cases
    Adele Woodhouse
    NeuroRepair Group, School of Medicine, Private Bag 29, University of Tasmania, Hobart, Tasmania 7001, Australia
    Neurobiol Dis 22:323-33. 2006
  6. ncbi request reprint Does beta-amyloid plaque formation cause structural injury to neuronal processes?
    Adele Woodhouse
    NeuroRepair Group, School of Medicine, University of Tasmania, Australia
    Neurotox Res 7:5-15. 2005
  7. pmc The native copper- and zinc-binding protein metallothionein blocks copper-mediated Abeta aggregation and toxicity in rat cortical neurons
    Roger S Chung
    NeuroRepair Group, Menzies Research Institute, University of Tasmania, Hobart, Australia
    PLoS ONE 5:e12030. 2010
  8. ncbi request reprint Spinal cord tissue affects ensheathing cell proliferation and apoptosis
    Adele Woodhouse
    NeuroRepair Group, School of Medicine, University of Tasmania, Private Bag 24, Hobart, Tasmania 7001, Australia
    Neuroreport 16:737-40. 2005
  9. doi request reprint Axonopathy and cytoskeletal disruption in degenerative diseases of the central nervous system
    James C Vickers
    NeuroRepair Group and Wicking Dementia Research and Education Centre, Menzies Research Institute, University of Tasmania, Hobart, Tasmania, Australia
    Brain Res Bull 80:217-23. 2009

Detail Information

Publications9

  1. ncbi request reprint Vaccination strategies for Alzheimer's disease: A new hope?
    Adele Woodhouse
    School of Medicine, NeuroRepair Group, University of Tasmania, Hobart, Tasmania, Australia
    Drugs Aging 24:107-19. 2007
    ..The vigour of international research on immunotherapy for AD provides significant hope for a strong therapeutic lead for the escalating number of individuals who will develop this otherwise incurable condition...
  2. ncbi request reprint Cytoplasmic cytochrome c immunolabelling in dystrophic neurites in Alzheimer's disease
    Adele Woodhouse
    NeuroRepair Group, School of Medicine, University of Tasmania, Private Bag 29, Hobart, TAS, 7001 Australia
    Acta Neuropathol 112:429-37. 2006
    ..Although cytochrome c release is indicative of the activation of the intrinsic apoptotic pathway, cytoplasmic cytochrome c may also indicate mitochondrial damage or dysfunction...
  3. ncbi request reprint Dystrophic neurites in TgCRND8 and Tg2576 mice mimic human pathological brain aging
    Adele Woodhouse
    NeuroRepair Group, Menzies Research Institute, 43 Collins Street, Hobart, 7001 Tasmania, Australia
    Neurobiol Aging 30:864-74. 2009
    ..These results suggest that neuronal pathology in these mice represent an accurate and valuable model for understanding, and developing treatments for, the early brain changes of AD...
  4. doi request reprint Cytoskeletal alterations differentiate presenilin-1 and sporadic Alzheimer's disease
    Adele Woodhouse
    Wicking Dementia Research and Education Centre and NeuroRepair Group, Menzies Research Institute, Private Bag 29, Hobart, TAS, 7001, Australia
    Acta Neuropathol 117:19-29. 2009
    ..These differences in cytoskeletal pathology in PS1 cases suggest an accelerated rate of neuritic pathology development, potentially due to mutant PS1 influencing multiple pathogenic pathways...
  5. ncbi request reprint No difference in expression of apoptosis-related proteins and apoptotic morphology in control, pathologically aged and Alzheimer's disease cases
    Adele Woodhouse
    NeuroRepair Group, School of Medicine, Private Bag 29, University of Tasmania, Hobart, Tasmania 7001, Australia
    Neurobiol Dis 22:323-33. 2006
    ..Apoptosis may not play a major role in the pathogenesis of neuronal degeneration of AD...
  6. ncbi request reprint Does beta-amyloid plaque formation cause structural injury to neuronal processes?
    Adele Woodhouse
    NeuroRepair Group, School of Medicine, University of Tasmania, Australia
    Neurotox Res 7:5-15. 2005
    ..Identification of the key neuronal alterations underlying the pathology of Alzheimer's disease may provide new avenues for therapeutic intervention...
  7. pmc The native copper- and zinc-binding protein metallothionein blocks copper-mediated Abeta aggregation and toxicity in rat cortical neurons
    Roger S Chung
    NeuroRepair Group, Menzies Research Institute, University of Tasmania, Hobart, Australia
    PLoS ONE 5:e12030. 2010
    ..A major pathological hallmark of AD is the deposition of insoluble extracellular beta-amyloid (Abeta) plaques. There are compelling data suggesting that Abeta aggregation is catalysed by reaction with the metals zinc and copper...
  8. ncbi request reprint Spinal cord tissue affects ensheathing cell proliferation and apoptosis
    Adele Woodhouse
    NeuroRepair Group, School of Medicine, University of Tasmania, Private Bag 24, Hobart, Tasmania 7001, Australia
    Neuroreport 16:737-40. 2005
    ..These results suggest that delaying transplantation after spinal cord injury may be beneficial to ensheathing cell survival...
  9. doi request reprint Axonopathy and cytoskeletal disruption in degenerative diseases of the central nervous system
    James C Vickers
    NeuroRepair Group and Wicking Dementia Research and Education Centre, Menzies Research Institute, University of Tasmania, Hobart, Tasmania, Australia
    Brain Res Bull 80:217-23. 2009
    ..The identification of a degenerative process initiated in the axon may provide new therapeutic targets for early intervention to inhibit the grim outcomes related to the progression of these diseases...