Bruce D Wines

Summary

Affiliation: University of Melbourne
Country: Australia

Publications

  1. ncbi IgA receptors in health and disease
    Bruce D Wines
    Helen Macpherson Smith Trust Inflammatory Disease Laboratory, The Macfarlane Burnet Institute for Medical Research and Public Health, Austin Health Campus, Heidelberg, Victoria, Australia
    Tissue Antigens 68:103-14. 2006
  2. ncbi A common site of the Fc receptor gamma subunit interacts with the unrelated immunoreceptors FcalphaRI and FcepsilonRI
    Bruce D Wines
    Helen Macpherson Smith Trust Inflammatory Disease Laboratory, The Macfarlane Burnet Institute for Medical Research and Public Health, Austin Health Campus, Heidelberg, Victoria 3084, Australia
    J Biol Chem 281:17108-13. 2006
  3. pmc Soluble FcgammaRIIa inhibits rheumatoid factor binding to immune complexes
    Bruce D Wines
    Departments of Rheumatology and Medicine, The Austin Research Institute, Austin Repatriation Medical Centre, Heidelberg, Victoria, Australia
    Immunology 109:246-54. 2003
  4. ncbi Fc receptor gamma chain residues at the interface of the cytoplasmic and transmembrane domains affect association with FcalphaRI, surface expression, and function
    Bruce D Wines
    Helen Macpherson Smith Trust Inflammatory Disease Laboratory, Austin Research Institute, Austin Repatriation Medical Centre, Studley Road, Heidelberg, Victoria, 3084, Australia
    J Biol Chem 279:26339-45. 2004
  5. ncbi A competitive mechanism for staphylococcal toxin SSL7 inhibiting the leukocyte IgA receptor, Fc alphaRI, is revealed by SSL7 binding at the C alpha2/C alpha3 interface of IgA
    Bruce D Wines
    Helen Macpherson Smith Trust Inflammatory Disease Laboratory, The Austin Research Institute, Austin Health, Heidelberg, Victoria 3084, Australia
    J Biol Chem 281:1389-93. 2006
  6. pmc Structural basis for evasion of IgA immunity by Staphylococcus aureus revealed in the complex of SSL7 with Fc of human IgA1
    Paul A Ramsland
    The Inflammatory Disease and Structural Immunology Laboratories, The Burnet Institute, Austin Hospital, Studley Road, Heidelberg, Victoria 3084, Australia
    Proc Natl Acad Sci U S A 104:15051-6. 2007
  7. ncbi Alteration of the Fc gamma RIIa dimer interface affects receptor signaling but not ligand binding
    Maree S Powell
    The Macfarlane Burnet Institute for Medical Research and Public Health Limited, Austin Health, Heidelberg, Victoria, Australia
    J Immunol 176:7489-94. 2006
  8. ncbi An FcgammaRIIa-binding peptide that mimics the interaction between FcgammaRIIa and IgG
    Angela C Cendron
    Burnet Institute, Austin Campus, Studley Road, Heidelberg, VIC 3084, Australia
    Mol Immunol 45:307-19. 2008
  9. ncbi Surface display of IgG Fc on baculovirus vectors enhances binding to antigen-presenting cells and cell lines expressing Fc receptors
    John C Martyn
    The Macfarlane Burnet Institute for Medical Research and Public Health, Melbourne, Vic, Australia
    Arch Virol 154:1129-38. 2009
  10. ncbi IgG purification
    Maree S Powell
    The Helen M Schutt Trust Laboratory, The Austin Research Institute, The Austin and Repatriation Medical Center, Heidelberg, Victoria, Australia
    Methods Mol Biol 251:341-50. 2004

Collaborators

Detail Information

Publications12

  1. ncbi IgA receptors in health and disease
    Bruce D Wines
    Helen Macpherson Smith Trust Inflammatory Disease Laboratory, The Macfarlane Burnet Institute for Medical Research and Public Health, Austin Health Campus, Heidelberg, Victoria, Australia
    Tissue Antigens 68:103-14. 2006
    ..Finally, the therapeutic application of various IgA receptors has been sought in the areas of infectious disease, vaccines, and cancer...
  2. ncbi A common site of the Fc receptor gamma subunit interacts with the unrelated immunoreceptors FcalphaRI and FcepsilonRI
    Bruce D Wines
    Helen Macpherson Smith Trust Inflammatory Disease Laboratory, The Macfarlane Burnet Institute for Medical Research and Public Health, Austin Health Campus, Heidelberg, Victoria 3084, Australia
    J Biol Chem 281:17108-13. 2006
    ..Taken together these data provide a molecular basis for understanding how disparate receptor families assemble with the FcRgamma subunit...
  3. pmc Soluble FcgammaRIIa inhibits rheumatoid factor binding to immune complexes
    Bruce D Wines
    Departments of Rheumatology and Medicine, The Austin Research Institute, Austin Repatriation Medical Centre, Heidelberg, Victoria, Australia
    Immunology 109:246-54. 2003
    ..We propose that the high concentrations of soluble FcgammaR found during inflammation can affect the properties of ICs and their interaction with the immune system...
  4. ncbi Fc receptor gamma chain residues at the interface of the cytoplasmic and transmembrane domains affect association with FcalphaRI, surface expression, and function
    Bruce D Wines
    Helen Macpherson Smith Trust Inflammatory Disease Laboratory, Austin Research Institute, Austin Repatriation Medical Centre, Studley Road, Heidelberg, Victoria, 3084, Australia
    J Biol Chem 279:26339-45. 2004
    ..Thus, these TM residues of FcR-gamma are important for association with FcalphaRI and probably other activating LRC members but not with the classical FcR, FcepsilonRI...
  5. ncbi A competitive mechanism for staphylococcal toxin SSL7 inhibiting the leukocyte IgA receptor, Fc alphaRI, is revealed by SSL7 binding at the C alpha2/C alpha3 interface of IgA
    Bruce D Wines
    Helen Macpherson Smith Trust Inflammatory Disease Laboratory, The Austin Research Institute, Austin Health, Heidelberg, Victoria 3084, Australia
    J Biol Chem 281:1389-93. 2006
    ..aureus IgA binding factor and unrelated factors from streptococci are functionally convergent, all targeting a number of the same residues in the IgA Fc, which comprise the binding site for the leukocyte IgA receptor, Fc alphaRI...
  6. pmc Structural basis for evasion of IgA immunity by Staphylococcus aureus revealed in the complex of SSL7 with Fc of human IgA1
    Paul A Ramsland
    The Inflammatory Disease and Structural Immunology Laboratories, The Burnet Institute, Austin Hospital, Studley Road, Heidelberg, Victoria 3084, Australia
    Proc Natl Acad Sci U S A 104:15051-6. 2007
    ..Thus, the ability of S. aureus to subvert IgA-mediated immunity is likely to facilitate survival in mucosal environments such as the nasal passage and may contribute to systemic infections...
  7. ncbi Alteration of the Fc gamma RIIa dimer interface affects receptor signaling but not ligand binding
    Maree S Powell
    The Macfarlane Burnet Institute for Medical Research and Public Health Limited, Austin Health, Heidelberg, Victoria, Australia
    J Immunol 176:7489-94. 2006
    ..The data suggest that the ligand binding and the dimer interface are distinct regions within the receptor, and noncovalent dimerization of FcgammaRIIa may be an essential feature of the FcgammaRIIa signaling cascade...
  8. ncbi An FcgammaRIIa-binding peptide that mimics the interaction between FcgammaRIIa and IgG
    Angela C Cendron
    Burnet Institute, Austin Campus, Studley Road, Heidelberg, VIC 3084, Australia
    Mol Immunol 45:307-19. 2008
    ....
  9. ncbi Surface display of IgG Fc on baculovirus vectors enhances binding to antigen-presenting cells and cell lines expressing Fc receptors
    John C Martyn
    The Macfarlane Burnet Institute for Medical Research and Public Health, Melbourne, Vic, Australia
    Arch Virol 154:1129-38. 2009
    ..These novel baculoviral vectors, which target cells of the immune system that express FcRs, have potential applications for vaccination or gene therapy...
  10. ncbi IgG purification
    Maree S Powell
    The Helen M Schutt Trust Laboratory, The Austin Research Institute, The Austin and Repatriation Medical Center, Heidelberg, Victoria, Australia
    Methods Mol Biol 251:341-50. 2004
  11. ncbi The crystal structure of staphylococcal superantigen-like protein 11 in complex with sialyl Lewis X reveals the mechanism for cell binding and immune inhibition
    Matthew C Chung
    Maurice Wilkins Centre, University of Auckland, Auckland, New Zealand
    Mol Microbiol 66:1342-55. 2007
    ..A single amino acid mutation in the carbohydrate binding site abolished all SSL11 binding. Thus, SSL11 is a staphylococcal protein that targets myeloid cells by binding sialyllactosamine-containing glycoproteins...
  12. ncbi The mechanism underlying defective Fcgamma receptor-mediated phagocytosis by HIV-1-infected human monocyte-derived macrophages
    Edwin Leeansyah
    AIDS Pathogenesis and Clinical Research Program, The Macfarlane Burnet Institute for Medical Research and Public Health, 85 Commercial Road, Melbourne, Australia 3004
    J Immunol 178:1096-104. 2007
    ..These data suggest that HIV-1 infection may affect only gamma-chain-dependent FcgammaR functions, but that this is not restricted to HIV-1-infected cells...