David P Wilson

Summary

Affiliation: University of New South Wales
Country: Australia

Publications

  1. pmc HIV and syphilis co-infection increasing among men who have sex with men in China: a systematic review and meta-analysis
    Eric P F Chow
    The Kirby Institute for Infection and Immunity in Society, Faculty of Medicine, University of New South Wales, Sydney, Australia
    PLoS ONE 6:e22768. 2011
  2. pmc Characterizing trends in HIV infection among men who have sex with men in Australia by birth cohorts: results from a modified back-projection method
    Handan Wand
    National Centre in HIV Epidemiology and Clinical Research, Sydney, Australia
    J Int AIDS Soc 12:19. 2009
  3. doi request reprint Interpreting sexually transmissible infection prevention trials by adjusting for the magnitude of exposure
    David P Wilson
    National Centre in HIV Epidemiology and Clinical Research, The University of New South Wales, Sydney, Australia
    Clin Trials 7:36-43. 2010
  4. ncbi request reprint Chemoprophylaxis is likely to be acceptable and could mitigate syphilis epidemics among populations of gay men
    David P Wilson
    National Centre in HIV Epidemiology and Clinical Research, The University of New South Wales, Sydney, Australia
    Sex Transm Dis 38:573-9. 2011
  5. ncbi request reprint Relation between HIV viral load and infectiousness: a model-based analysis
    David P Wilson
    National Centre in HIV Epidemiology and Clinical Research, University of New South Wales, Sydney, NSW, Australia
    Lancet 372:314-20. 2008
  6. ncbi request reprint Importance of promoting HIV testing for preventing secondary transmissions: modelling the Australian HIV epidemic among men who have sex with men
    David P Wilson
    National Centre in HIV Epidemiology and Clinical Research, The University of New South Wales, Sydney, NSW 2010, Australia
    Sex Health 6:19-33. 2009
  7. doi request reprint Ocular pathologic response elicited by Chlamydia organisms and the predictive value of quantitative modeling
    David P Wilson
    National Centre in HIV Epidemiology and Clinical Research, The University of New South Wales, Sydney, New South Wales, Australia
    J Infect Dis 199:1780-9. 2009
  8. doi request reprint Serosorting may increase the risk of HIV acquisition among men who have sex with men
    David P Wilson
    National Centre in HIV Epidemiology and Clinical Research, Faculty of Medicine, The University of New South Wales, Sydney, Australia
    Sex Transm Dis 37:13-7. 2010
  9. ncbi request reprint Modelling based on Australian HIV notifications data suggests homosexual age mixing is primarily assortative
    David P Wilson
    National Centre in HIV Epidemiology and Clinical Research, University of New South Wales, Sydney, New South Wales 2010, Australia
    J Acquir Immune Defic Syndr 51:356-60. 2009
  10. doi request reprint Sex workers can be screened too often: a cost-effectiveness analysis in Victoria, Australia
    David P Wilson
    National Centre in HIV Epidemiology and Clinical Research, The University of New South Wales, Sydney, Australia
    Sex Transm Infect 86:117-25. 2010

Collaborators

Detail Information

Publications93

  1. pmc HIV and syphilis co-infection increasing among men who have sex with men in China: a systematic review and meta-analysis
    Eric P F Chow
    The Kirby Institute for Infection and Immunity in Society, Faculty of Medicine, University of New South Wales, Sydney, Australia
    PLoS ONE 6:e22768. 2011
    ..This study aims to estimate the magnitude and changing trends of HIV, syphilis and HIV-syphilis co-infections among men who have sex with men (MSM) in China during 2003-2008 through a systematic review of published literature...
  2. pmc Characterizing trends in HIV infection among men who have sex with men in Australia by birth cohorts: results from a modified back-projection method
    Handan Wand
    National Centre in HIV Epidemiology and Clinical Research, Sydney, Australia
    J Int AIDS Soc 12:19. 2009
    ..abstract:..
  3. doi request reprint Interpreting sexually transmissible infection prevention trials by adjusting for the magnitude of exposure
    David P Wilson
    National Centre in HIV Epidemiology and Clinical Research, The University of New South Wales, Sydney, Australia
    Clin Trials 7:36-43. 2010
    ..Exposures to sexually transmitted infections are discrete identifiable events. Interventions to prevent sexually transmitted infections have a certain probability of effectiveness in reducing risk in any given event...
  4. ncbi request reprint Chemoprophylaxis is likely to be acceptable and could mitigate syphilis epidemics among populations of gay men
    David P Wilson
    National Centre in HIV Epidemiology and Clinical Research, The University of New South Wales, Sydney, Australia
    Sex Transm Dis 38:573-9. 2011
    ..An innovative public health response could be the use of chemoprophylaxis. We sought out to determine the acceptability of syphilis chemoprophylaxis and its likely population effectiveness if it were adopted...
  5. ncbi request reprint Relation between HIV viral load and infectiousness: a model-based analysis
    David P Wilson
    National Centre in HIV Epidemiology and Clinical Research, University of New South Wales, Sydney, NSW, Australia
    Lancet 372:314-20. 2008
    ..We analysed the implications of this statement at a population level...
  6. ncbi request reprint Importance of promoting HIV testing for preventing secondary transmissions: modelling the Australian HIV epidemic among men who have sex with men
    David P Wilson
    National Centre in HIV Epidemiology and Clinical Research, The University of New South Wales, Sydney, NSW 2010, Australia
    Sex Health 6:19-33. 2009
    ..HIV infection (PHI), (c) on antiretroviral therapy?; and (ii) what is the expected epidemiological impact of (a) increasing the proportion of newly acquired HIV infections receiving early treatment, and (b) increasing HIV testing rates?..
  7. doi request reprint Ocular pathologic response elicited by Chlamydia organisms and the predictive value of quantitative modeling
    David P Wilson
    National Centre in HIV Epidemiology and Clinical Research, The University of New South Wales, Sydney, New South Wales, Australia
    J Infect Dis 199:1780-9. 2009
    ..Chlamydia organisms are a significant cause of ocular and genital tract disease worldwide. Acute inflammatory responses are largely responsible for pathologic changes...
  8. doi request reprint Serosorting may increase the risk of HIV acquisition among men who have sex with men
    David P Wilson
    National Centre in HIV Epidemiology and Clinical Research, Faculty of Medicine, The University of New South Wales, Sydney, Australia
    Sex Transm Dis 37:13-7. 2010
    ..However, the effectiveness of serosorting as a strategy to reduce HIV risk is unclear, especially since it depends on the frequency of HIV testing...
  9. ncbi request reprint Modelling based on Australian HIV notifications data suggests homosexual age mixing is primarily assortative
    David P Wilson
    National Centre in HIV Epidemiology and Clinical Research, University of New South Wales, Sydney, New South Wales 2010, Australia
    J Acquir Immune Defic Syndr 51:356-60. 2009
    ..To understand age-specific sexual mixing patterns of men who have sex with men in Australia, for behavioral insight, and to determine which age groups are at greatest risk of acquiring HIV in the future...
  10. doi request reprint Sex workers can be screened too often: a cost-effectiveness analysis in Victoria, Australia
    David P Wilson
    National Centre in HIV Epidemiology and Clinical Research, The University of New South Wales, Sydney, Australia
    Sex Transm Infect 86:117-25. 2010
    ..We aimed to conduct a cost-effectiveness analysis of the financial cost of the testing policy versus the health benefits of averting the transmission of HIV, syphilis, chlamydia and gonorrhoea to clients...
  11. pmc How far will we need to go to reach HIV-infected people in rural South Africa?
    David P Wilson
    Disease Modeling Group, Semel Institute for Neuroscience and Human Behavior, and UCLA AIDS Institute, School of Medicine, University of California at Los Angeles, Los Angeles, CA 90024, USA
    BMC Med 5:16. 2007
    ..Specifically, we address the health policy question 'How far will we need to go to reach PLWHA in rural KwaZulu-Natal?'...
  12. doi request reprint Qualitative exploration of HIV-related sexual behaviours and multiple partnerships among Chinese men who have sex with men living in a rural area of Yunnan Province, China
    Eric P F Chow
    The Kirby Institute, University of New South Wales, Sydney, NSW 2052, Australia
    Sex Health 10:533-40. 2013
    ..The HIV epidemic has been spreading rapidly among men who have sex with men (MSM) in China. The present study explored the pattern of HIV-related high-risk sexual practices among MSM in a rural Chinese setting...
  13. doi request reprint Estimating the cost-effectiveness of needle-syringe programs in Australia
    Jisoo A Kwon
    The Kirby Institute, The University of New South Wales, Sydney, Australia
    AIDS 26:2201-10. 2012
    ..To evaluate the impact and cost-effectiveness of needle-syringe programs (NSPs) with respect to HIV and hepatitis C virus (HCV) infections among Australian injecting drug users (IDUs)...
  14. doi request reprint Will changes in gay men's sexual behavior reduce syphilis rates?
    Richard T Gray
    Kirby Institute for Immunity Infection and Society, University of New South Wales, Sydney, Australia
    Sex Transm Dis 38:1151-8. 2011
    ..Reducing rates of partner change and increasing condom usage among gay men are obvious targets for potentially reducing syphilis transmission among gay men...
  15. doi request reprint Frequent testing of highly sexually active gay men is required to control syphilis
    Richard T Gray
    National Centre in HIV Epidemiology and Clinical Research, The University of New South Wales, Sydney, Australia
    Sex Transm Dis 37:298-305. 2010
    ..The incidence of syphilis infections has been substantially increasing in gay men in the developed world...
  16. ncbi request reprint Using mathematical modelling to help explain the differential increase in HIV incidence in New South Wales, Victoria and Queensland: importance of other sexually transmissible infections
    Alexander Hoare
    National Centre in HIV Epidemiology and Clinical Research, Faculty of Medicine, University of New South Wales, Level 2, 376 Victoria Street, Sydney, NSW 2010, Australia
    Sex Health 5:169-87. 2008
    ....
  17. ncbi request reprint HIV disease burden and related risk behaviours among men who have sex with men in Yuxi Prefecture, Yunnan Province, China: 2010-2011
    Eric P F Chow
    Faculty of Medicine, The Kirby Institute, University of New South Wales, Sydney, NSW, 2052, Australia
    AIDS Behav 17:2387-94. 2013
    ..HIV prevalence is high among Chinese MSM in Yunnan. Common bisexual behaviours and low consistent condom use with female partners suggest a potential spread of HIV from MSM to females. ..
  18. pmc Increased HIV testing will modestly reduce HIV incidence among gay men in NSW and would be acceptable if HIV testing becomes convenient
    Richard T Gray
    The Kirby Institute, University of New South Wales, Sydney, Australia
    PLoS ONE 8:e55449. 2013
    ....
  19. doi request reprint Increasing gay men's testing rates and enhancing partner notification can reduce the incidence of syphilis
    Ian Down
    The Kirby Institute, University of New South Wales, Sydney, NSW, Australia
    Sex Health 9:472-80. 2012
    ..We sought to determine whether gay men would be willing to increase syphilis testing and partner notification, and assessed the possible epidemiological impact these changes might have in the Australian population...
  20. doi request reprint High annual syphilis testing rates among gay men in Australia, but insufficient retesting
    Rebecca Guy
    Kirby Institute, University of New South Wales, Sydney, Australia
    Sex Transm Dis 39:268-75. 2012
    ..Since 2000, infectious syphilis notifications have increased substantially among Australian gay men. We describe testing at a frequency lower than guidelines recommend...
  21. doi request reprint Would gay men change their sexual behavior to reduce syphilis rates?
    Pol Dominic McCann
    Kirby Institute for Infection and Immunity in Society, University of New South Wales, Sydney, New South Wales, Australia
    Sex Transm Dis 38:1145-50. 2011
    ..We aimed to elicit information on the acceptability of behavior change interventions among gay men for reducing syphilis transmission...
  22. pmc Population movement can sustain STI prevalence in remote Australian indigenous communities
    Ben B Hui
    The Kirby Institute, University of New South Wales, Sydney, NSW 2052, Australia
    BMC Infect Dis 13:188. 2013
    ..The high levels of population movement known to occur between remote communities may contribute to these high rates...
  23. doi request reprint High rates of late HIV diagnosis among people who inject drugs compared to men who have sex with men and heterosexual men and women in Australia
    Handan Wand
    Faculty of Medicine, Kirby Institute, University of New South Wales, 45 Beach Street, Coogee, Sydney, NSW, 2034, Australia
    AIDS Behav 17:235-41. 2013
    ..Ongoing prevention efforts need to be coupled with targeted testing and treatment efforts to increase the diagnosis of recent infection in PWID and reduce apparent inequities in access to screening...
  24. doi request reprint Modelling the epidemiological impact of scaling up HIV testing and antiretroviral treatment in China
    Lei Zhang
    The Kirby Institute, University of New South Wales, Darlinghurst, Sydney, NSW 2010, Australia
    Sex Health 9:261-71. 2012
    ..The HIV epidemic in China has been increasing. In response, a 5-year action plan in China has prioritised the scale-up of HIV testing and treatment...
  25. ncbi request reprint What impact might the economic crisis have on HIV epidemics in Southeast Asia?
    Richard T Gray
    National Centre in HIV Epidemiology and Clinical Research, The University of New South Wales, Sydney, Australia
    Curr HIV Res 7:656-65. 2009
    ..To evaluate the potential impact of the current global economic crisis (GEC) on the spread of HIV...
  26. ncbi request reprint Expected epidemiological impacts of introducing an HIV vaccine in Thailand: a model-based analysis
    Karen Schneider
    The Kirby Institute for Infection and Immunity in Society, The University of New South Wales, Sydney, Australia
    Vaccine 29:6086-91. 2011
    ..The RV144 trial conducted in Thailand was the first to demonstrate modest protective efficacy of an HIV vaccine. Its estimated initial efficacy was ∼74%, but this waned considerably over time...
  27. doi request reprint High HIV prevalence and risk of infection among rural-to-urban migrants in various migration stages in China: a systematic review and meta-analysis
    Lei Zhang
    Kirby Institute, Faculty of Medicine, University of New South Wales, Sydney, Australia
    Sex Transm Dis 40:136-47. 2013
    ..Rural-to-urban migrants represent 17% of the total Chinese population and are considered a potential high-risk bridging population of HIV infection between urban and rural China...
  28. ncbi request reprint HIV incidence trends vary between jurisdictions in Australia: an extended back-projection analysis of men who have sex with men
    Kylie Ann Mallitt
    National Centre in HIV Epidemiology and Clinical Research, University of New South Wales, Darlinghurst, Sydney, Australia
    Sex Health 9:138-43. 2012
    ..We use national population surveillance data to estimate the incidence of HIV infections among MSM by jurisdiction and infer the proportion of undiagnosed infections...
  29. pmc Per-contact probability of HIV transmission in homosexual men in Sydney in the era of HAART
    Fengyi Jin
    National Centre in HIV Epidemiology and Clinical Research, University of New South Wales, Darlinghurst, Australia
    AIDS 24:907-13. 2010
    ..The objective of this study is to estimate per-contact probability of HIV transmission in homosexual men due to unprotected anal intercourse (UAI) in the era of HAART...
  30. pmc Using population attributable risk to choose HIV prevention strategies in men who have sex with men
    Rebecca J Guy
    Kirby Institute formerly the National Centre in HIV Epidemiology and Clinical Research, Sydney, NSW, Australia
    BMC Public Health 11:247. 2011
    ..We undertook an analysis of the potential population impact and cost saving that would likely result from modifying key HIV risk factors among men who have sex with men (MSM) in Sydney, Australia...
  31. ncbi request reprint Expected epidemiological impact of the introduction of a partially effective HIV vaccine among men who have sex with men in Australia
    Richard T Gray
    National Centre in HIV Epidemiology and Clinical Research, Faculty of Medicine, The University of New South Wales, Sydney, NSW, Australia
    Vaccine 29:6125-9. 2011
    ..However, the moderately low population-level impact suggests that a public health strategy involving such a vaccine should be supplemented with other biomedical and educational strategies...
  32. pmc Hidden drug resistant HIV to emerge in the era of universal treatment access in Southeast Asia
    Alexander Hoare
    National Centre in HIV Epidemiology and Clinical Research, The University of New South Wales, Sydney, Australia
    PLoS ONE 5:e10981. 2010
    ..Universal access to first-line antiretroviral therapy (ART) for HIV infection is becoming more of a reality in most low and middle income countries in Asia. However, second-line therapies are relatively scarce...
  33. doi request reprint Coverage is the key for effective screening of Chlamydia trachomatis in Australia
    David G Regan
    National Centre in HIV Epidemiology and Clinical Research, University of New South Wales, Sydney, New South Wales, Australia
    J Infect Dis 198:349-58. 2008
    ..In response, the Australian government is planning to implement systematic screening and testing. Several decisions must be made, including whom to screen...
  34. doi request reprint The potential impact of new generation molecular point-of-care tests on gonorrhoea and chlamydia in a setting of high endemic prevalence
    Ben B Hui
    The Kirby Institute, University of New South Wales, Sydney, NSW 2052, Australia
    Sex Health 10:348-56. 2013
    ..However, evaluation of the cost-effectiveness of POC testing needs to be made before widespread implementation of this technology can be considered. ..
  35. ncbi request reprint Estimating HIV incidence among female partners of bisexual men in China
    Eric P F Chow
    The Kirby Institute, University of New South Wales, CFI Building, Corner West and Boundary Streets, Darlinghurst, Sydney, NSW 2010, Australia
    Int J Infect Dis 16:e312-20. 2012
    ..HIV prevalence among men who have sex with men (MSM) in China is rapidly increasing. The majority of Chinese MSM engage in bisexual behaviors and their female partners may be at high risk of HIV infection...
  36. pmc Predicting the epidemiological impact of antiretroviral allocation strategies in KwaZulu-Natal: the effect of the urban-rural divide
    David P Wilson
    Semel Institute for Neuroscience and Human Behavior, and Department of Biomathematics, David Geffen School of Medicine, University of California, 1100 Glendon Avenue, Penthouse 2, Los Angeles, CA 90024, USA
    Proc Natl Acad Sci U S A 103:14228-33. 2006
    ..Decisions about allocating scarce drugs should consider treatment equity as well as epidemiological consequences. Notably, a Durban-only DAS would lead to new disparities in healthcare between urban and rural areas in KwaZulu-Natal...
  37. pmc Estimating the infectivity of CCR5-tropic simian immunodeficiency virus SIV(mac251) in the gut
    David P Wilson
    Department of Haematology, Prince of Wales Hospital, University of New South Wales, Kensington, New South Wales, Australia
    J Virol 81:8025-9. 2007
    ..6P infection, but this higher infectivity is offset by a lower average peak viral load in SIV(mac251). Thus, the dynamics of target cell infection and death are remarkably similar between a CXCR4- and a CCR5-tropic infection in vivo...
  38. pmc Trends in and determinants of loss to follow up and early mortality in a rapid expansion of the antiretroviral treatment program in Vietnam: findings from 13 outpatient clinics
    Dam Anh Tran
    Kirby Institute, The University of New South Wales, Sydney, New South Wales, Australia National Drug Alcohol Research Centre, The University of New South Wales, Sydney, New South Wales, Australia
    PLoS ONE 8:e73181. 2013
    ..This study aims to describe the trends in and determinants of six month mortality and loss to follow up (LTFU) during 2005-2009 in 13 outpatient clinics in Vietnam...
  39. ncbi request reprint HIV prevalence in China: integration of surveillance data and a systematic review
    Lei Zhang
    The Kirby Institute, University of New South Wales, Sydney, NSW, Australia Comprehensive AIDS Research Center, Tsinghua University, Beijing, China Electronic address
    Lancet Infect Dis 13:955-63. 2013
    ..We aimed to understand the complexity of HIV epidemics in China by systematically analysing prevalence trends by data source, region, population group, and time period...
  40. pmc Currently available medications in resource-rich settings may not be sufficient for lifelong treatment of HIV
    James Jansson
    The Kirby Institute, University of New South Wales, Sydney NSW 2052, Australia
    AIDS 27:1245-51. 2013
    ..Our study aims to project the life expectancy of PLHIV in a resource-rich setting in the context of the currently available antiretroviral treatments...
  41. pmc HIV and sexually transmissible infections among money boys in China: a data synthesis and meta-analysis
    Eric P F Chow
    The Kirby Institute, University of New South Wales, Sydney, Australia
    PLoS ONE 7:e48025. 2012
    ..Commercial sex workers within the population of men who have sex with men (MSM) in China, known as 'money boys' (MBs), are perceived to be at higher risk for HIV and other sexually-transmissible infections (STIs)...
  42. pmc Distributions and trends in sexual behaviors and HIV incidence among men who have sex with men in China
    Lei Zhang
    The Kirby Institute, University of New South Wales, Sydney, NSW 2052, Australia
    BMC Public Health 12:546. 2012
    ..This study aims to investigate the trends HIV incidence rates in relation to their risk sexual behaviors and partnership types among Chinese MSM...
  43. doi request reprint Patterns of condom use among men who have sex with men in China: a systematic review and meta-analysis
    Eric P F Chow
    National Centre in HIV Epidemiology and Clinical Research, The University of New South Wales, CFI Building, Corner of West and Boundary Streets, Darlinghurst, Sydney, NSW 2010, Australia
    AIDS Behav 16:653-63. 2012
    ..7-38.9%) in 2006-2008. Condom use was greatest and increasing among commercial sex partners, from 49.8 to 75.2% at last anal sex. Further condom promotion is still required to reduce the incidence of HIV infection among MSM in China...
  44. ncbi request reprint Could implementation of Australia's national gay men's syphilis action plan have an indirect effect on the HIV epidemic?
    Alexander Hoare
    National Centre in HIV Epidemiology and Clinical Research, The University of New South Wales, Sydney, Australia
    Sex Health 9:144-51. 2012
    ..Sexually transmissible infections (STI) are a biologically plausible cofactor for increasing HIV transmission. We pose the question: could strategies purely targeting syphilis also have an indirect impact on HIV incidence?..
  45. pmc The prevalence of sexually transmitted infections in Papua New Guinea: a systematic review and meta-analysis
    Andrew Vallely
    National Centre in HIV Epidemiology and Clinical Research, University of New South Wales, Sydney, Australia
    PLoS ONE 5:e15586. 2010
    ..As sexually transmitted infections (STIs) may be important co-factors in HIV transmission nationally, it is timely to conduct a systematic review of STI prevalences to inform national policy on sexual health and HIV/STI prevention...
  46. ncbi request reprint Cost-effectiveness of antiretroviral therapy expansion strategies in Vietnam
    Dam Anh Tran
    1 Kirby Institute, The University of New South Wales, Sydney, New South Wales, Australia
    AIDS Patient Care STDS 28:365-71. 2014
    ..It is imperative to increase treatment coverage for newly diagnosed PLHIV in Vietnam according to the current guidelines prior to increasing the CD4 threshold for ART initiation. ..
  47. pmc Spending of HIV resources in Asia and Eastern Europe: systematic review reveals the need to shift funding allocations towards priority populations
    Andrew P Craig
    The Kirby Institute, University of New South Wales, Sydney, NSW, Australia
    J Int AIDS Soc 17:18822. 2014
    ..Adopting a standard costing, impact evaluation, benefits calculation, analysis and reporting framework would enable cross comparisons and improve HIV resource prioritization and allocation. ..
  48. ncbi request reprint Demand for HIV clinical services is increasing in Australia but supply is decreasing
    Kylie Ann Mallitt
    The Kirby Institute, University of New South Wales, Sydney, NSW 2010, Australia
    Sex Health 10:43-6. 2013
    ..The aim of this study was to quantify current HIV clinical service capacity in Australia...
  49. pmc What is the potential for bisexual men in China to act as a bridge of HIV transmission to the female population? Behavioural evidence from a systematic review and meta-analysis
    Eric P F Chow
    The Kirby Institute for Infection and Immunity in Society, University of New South Wales, Sydney, Australia
    BMC Infect Dis 11:242. 2011
    ..It is suggested that MSM could be a potential bridge of HIV transmission to the general female population. We investigated the bisexual behaviour of MSM in China through systematic review and meta-analysis...
  50. doi request reprint An economic case for providing free access to antiretroviral therapy for HIV-positive people in South Australia
    Kelly Jean Heymer
    Faculty of Medicine, The University of New South Wales, Sydney, NSW 2010, Australia
    Sex Health 9:220-6. 2012
    ..As financial constraints can be a barrier to accessing HIV antiretroviral therapy (ART), we argue for the removal of copayment requirements from HIV medications in South Australia...
  51. doi request reprint Modeling the impact of potential vaccines on epidemics of sexually transmitted Chlamydia trachomatis infection
    Richard T Gray
    National Centre in HIV Epidemiology and Clinical Research, University of New South Wales, Sydney, Australia
    J Infect Dis 199:1680-8. 2009
    ..We investigated the likely impact of vaccines on the prevalence of and morbidity due to Chlamydia trachomatis (chlamydia) infections in heterosexual populations...
  52. doi request reprint Economic evaluation of monitoring virologic responses to antiretroviral therapy in HIV-infected children in resource-limited settings
    Karen Schneider
    National Centre in HIV Epidemiology and Clinical Research, The University of New South Wales, Sydney, Australia
    AIDS 25:1143-51. 2011
    ..We investigated the cost-effectiveness and cost-utility of different frequencies of monitoring plasma viral load among HIV-positive children initiating ART in a resource-limited setting...
  53. doi request reprint How low can you go: the impact of a modestly effective HIV vaccine compared with male circumcision
    John M Kaldor
    National Centre in HIV Epidemiology and Clinical Research, The University of New South Wales, Darlinghurst, Sydney, NSW, Australia
    AIDS 24:2573-8. 2010
    ..In contrast, male circumcision is widely supported and has approximately twice the efficacy, but can only be targeted to half of the population. We question the vaccine efficacy required before being considered in prevention strategies...
  54. ncbi request reprint Modelling sexually transmitted infections: less is usually more for informing public health policy
    David G Regan
    National Centre in HIV Epidemiology and Clinical Research, The University of New South Wales, 316 Victoria Street, Darlinghurst, Sydney, NSW 2010, Australia
    Trans R Soc Trop Med Hyg 102:207-8. 2008
    ..The aim of models, after all, is to influence or change public health policy by providing rational forecasting based on sound scientific principles...
  55. doi request reprint Treatment for prevention of HIV transmission in a localised epidemic: the case for South Australia
    Kelly Jean Heymer
    National Centre in HIV Epidemiology and Clinical Research, The University of New South Wales, Darlinghurst, Sydney, NSW 2010, Australia
    Sex Health 8:280-94. 2011
    ..In this study, we explore the expected epidemiological impact of this strategy in a small population in which HIV transmission is predominantly confined to men who have sex with men (MSM)...
  56. pmc Methadone maintenance treatment participant retention and behavioural effectiveness in China: a systematic review and meta-analysis
    Lei Zhang
    The Kirby Institute, University of New South Wales, Sydney, New South Wales, Australia
    PLoS ONE 8:e68906. 2013
    ..The study systematically reviews Chinese MMT retention rates, reasons for drop out, and behavioural changes...
  57. doi request reprint HIV service capacity: identifying current and future areas of clinical shortage
    Kylie Ann Mallitt
    The Kirby Institute, University of New South Wales, Sydney, NSW 2052, Australia
    Sex Health 11:17-23. 2014
    ..Training of new HIV clinicians should be directed towards undersupplied areas. ..
  58. doi request reprint Trends in transfusion-transmissible infections among Australian blood donors from 2005 to 2010
    Tarana T A Lucky
    Kirby Institute, University of New South Wales, Sydney, Australia Australian Red Cross Blood Service, Melbourne, Australia
    Transfusion 53:2751-62. 2013
    ..This study determined recent trends in TTIs for which testing is conducted in Australia and described key attributes of infected blood donors...
  59. pmc Pattern of HIV testing and multiple sexual partnerships among men who have sex with men in China
    Eric P F Chow
    The Kirby Institute, University of New South Wales, Sydney, New South Wales, Australia
    BMC Infect Dis 13:549. 2013
    ..Low HIV testing levels and multiple partnerships among MSM are two major contributing factors to HIV transmission...
  60. pmc The potential cost and benefits of raltegravir in simplified second-line therapy among HIV infected patients in Nigeria and South Africa
    Karen Schneider
    The Kirby Institute for Infection and Immunity in Society, University of New South Wales, Sydney, New South Wales, Australia
    PLoS ONE 8:e54435. 2013
    ....
  61. pmc Structural barriers to timely initiation of antiretroviral treatment in Vietnam: findings from six outpatient clinics
    Dam Anh Tran
    National Drug and Alcohol Research Centre, The University of New South Wales, Sydney, Australia
    PLoS ONE 7:e51289. 2012
    ....
  62. ncbi request reprint Human immunodeficiency virus prevalence is increasing among men who have sex with men in China: findings from a review and meta-analysis
    Eric Pui Fung Chow
    The Kirby Institute for Infection and Immunity in Society, University of New South Wales, Sydney, Australia
    Sex Transm Dis 38:845-57. 2011
    ..This study aimed to estimate the magnitude and time trends of HIV prevalence among MSM in different geographical regions of China through a systemic review and meta-analysis...
  63. pmc Projected demographic profile of people living with HIV in Australia: planning for an older generation
    James Jansson
    The Kirby Institute, University of New South Wales, Sydney, Australia
    PLoS ONE 7:e38334. 2012
    ..Knowledge of demographic details such as age, geographical location and sex, will aid in the planning of training and resource allocation to effectively care for the future complex health needs of PLHIV...
  64. pmc Spatial constraints within the chlamydial host cell inclusion predict interrupted development and persistence
    Alexander Hoare
    National Centre in HIV Epidemiology and Clinical Research, Faculty of Medicine, University of New South Wales, Sydney, NSW, Australia
    BMC Microbiol 8:5. 2008
    ..The triggers that mediate the interchange between these particle types are unknown and yet this is crucial for understanding basic Chlamydia biology...
  65. pmc Sampling and sensitivity analyses tools (SaSAT) for computational modelling
    Alexander Hoare
    National Centre in HIV Epidemiology and Clinical Research, The University of New South Wales, Sydney, New South Wales, 2010, Australia
    Theor Biol Med Model 5:4. 2008
    ..To our knowledge, a number of the methods available in SaSAT for performing sensitivity analyses have not previously been used in epidemiological modelling and their usefulness in this context is demonstrated...
  66. doi request reprint The impact of needle and syringe programs on HIV and HCV transmissions in injecting drug users in Australia: a model-based analysis
    Jisoo A Kwon
    National Centre in HIV Epidemiology and Clinical Research, The University of New South Wales, Sydney, New South Wales, Australia
    J Acquir Immune Defic Syndr 51:462-9. 2009
    ..We aim to estimate how changes in sterile syringe distribution through needle-syringe programs (NSPs) may affect HIV and hepatitis C virus (HCV) incidence among injecting drug users (IDUs) in Australia...
  67. pmc Kinematics of intracellular chlamydiae provide evidence for contact-dependent development
    David P Wilson
    National Centre in HIV Epidemiology and Clinical Research, Faculty of Medicine, University of New South Wales, Level 2, 376 Victoria Street, Darlinghurst, Sydney, NSW 2010, Australia
    J Bacteriol 191:5734-42. 2009
    ....
  68. pmc The paradoxical effects of using antiretroviral-based microbicides to control HIV epidemics
    David P Wilson
    National Centre in HIV Epidemiology and Clinical Research, Faculty of Medicine, University of New South Wales, Level 2, 376 Victoria Street, Sydney NSW 2010, Australia
    Proc Natl Acad Sci U S A 105:9835-40. 2008
    ..Interventions that use ARV-based microbicides could have surprising consequences...
  69. doi request reprint European Christians are at the forefront in accepting evolution: results from an internet-based survey
    David P Wilson
    University of Newcastle, Callaghan, NSW, Australia
    Evol Dev 12:537-40. 2010
    ..Innovative strategies may be required to communicate evolutionary science effectively to non-European Christians...
  70. pmc Describing the Chinese HIV Surveillance System and the Influences of Political Structures and Social Stigma
    Lei Zhang
    Kirby Institute, University of New South Wales, Sydney, Australia
    Open AIDS J 6:163-8. 2012
    ..Social stigma and discrimination in health institutes are also key barriers for further improvements of HIV diagnosis and surveillance in China...
  71. pmc Is Back-Projection Methodology Still Relevant for Estimating HIV Incidence from National Surveillance Data?
    Kylie Ann Mallitt
    The Kirby Institute, University of New South Wales, Sydney, Australia
    Open AIDS J 6:108-11. 2012
    ..However, back-projection methodology should be used in conjunction with other corroborative methods to estimate current HIV incidence, and methods to combine the various techniques should be investigated...
  72. pmc Relative risk of renal disease among people living with HIV: a systematic review and meta-analysis
    Fakhrul M Islam
    The Kirby Institute, University of New South Wales, Sydney, NSW 2052, Australia
    BMC Public Health 12:234. 2012
    ..This study aimed to estimate the relative risk of renal disease among people living with HIV (PLHIV) compared to the HIV-uninfected population...
  73. pmc Trends in notifiable infectious diseases in China: implications for surveillance and population health policy
    Lei Zhang
    The Kirby Institute for Infection and Immunity in Society, Faculty of Medicine, University of New South Wales, Sydney, Australia
    PLoS ONE 7:e31076. 2012
    ..It is necessary to implement public health interventions that target HIV and relevant coinfections, address transmission associated with highly mobile populations, and reduce the risk of cross-species transmission of zoonotic pathogens...
  74. pmc Needle and syringe programs in Yunnan, China yield health and financial return
    Lei Zhang
    National Centre in HIV Epidemiology and Clinical Research, The University of New South Wales, Sydney, Australia
    BMC Public Health 11:250. 2011
    ..In this study we use data from Yunnan province, the province most affected by HIV in China, to (1) estimate the population benefits in terms of infections prevented due to the programs; (2) calculate the cost-effectiveness of NSPs...
  75. pmc Forecasting the Population-Level Impact of Reductions in HIV Antiretroviral Therapy in Papua New Guinea
    Richard T Gray
    National Centre in HIV Epidemiology and Clinical Research, Faculty of Medicine, The University of New South Wales, Ground Floor, CFI Building, Corner Boundary and West Streets, Darlinghurst, NSW 2010, Australia
    AIDS Res Treat 2011:891593. 2011
    ..7% increase). These results highlight that maintenance of ART and associated services through external funding is essential for the health and well-being of HIV-positive people in PNG...
  76. ncbi request reprint Risk factors associated with HIV/HCV infection among entrants in methadone maintenance treatment clinics in China: a systematic review and meta-analysis
    Xun Zhuang
    School of Public Health, Nantong University, Nantong, 9 Seyuan Road, Nantong, Jiangsu Province 226019, China
    Drug Alcohol Depend 126:286-95. 2012
    ....
  77. pmc An HIV epidemic is ready to emerge in the Philippines
    Anna C Farr
    National Centre in HIV Epidemiology and Clinical Research, University of New South Wales, Sydney, Australia
    J Int AIDS Soc 13:16. 2010
    ..The state of the HIV epidemic in the Philippines has been described as "low and slow", which is in stark contrast to many other countries in the region. A review of the conditions for HIV spread in the Philippines is necessary...
  78. doi request reprint Characteristics of HIV epidemics driven by men who have sex with men and people who inject drugs
    David P Wilson
    National Centre in HIV Epidemiology and Clinical Research, University of New South Wales, Sydney, Australia
    Curr Opin HIV AIDS 6:94-101. 2011
    ..To highlight the latest developments in mathematical transmission modelling of HIV epidemics among men who have sex with men (MSM) and people who inject drugs (PWID)...
  79. ncbi request reprint Understanding the mechanisms and limitations of immune control of HIV
    Miles P Davenport
    Department of Haematology, Prince of Wales Hospital and Centre for Vascular Research, University of New South Wales, Kensington, NSW, Australia
    Immunol Rev 216:164-75. 2007
    ..However, important questions remain as to whether differences in pathogenesis in HIV will lead to different 'rules of engagement' for immune control of virus...
  80. pmc HIV treatment as prevention: natural experiments highlight limits of antiretroviral treatment as HIV prevention
    David P Wilson
    The Kirby Institute, Faculty of Medicine, University of New South Wales, Sydney, New South Wales, Australia
    PLoS Med 9:e1001231. 2012
    ..This review suggests that the population-level impact of this strategy is likely to be considerably less than as inferred from ideal conditions...
  81. ncbi request reprint Australian trachoma surveillance annual report, 2010
    Carleigh S Cowling
    National Trachoma Surveillance Reporting Unit, The Kirby Institute, University of New South Wales, Darlinghurst, New South Wales, Australia
    Commun Dis Intell Q Rep 36:E242-50. 2012
    ..Treatment coverage of active cases and their contacts varied between jurisdictions from 64% to 90%. Trichiasis prevalence was 4% within the screened communities...
  82. pmc HIV and HCV prevalence among entrants to methadone maintenance treatment clinics in China: a systematic review and meta-analysis
    Xun Zhuang
    School of Public Health, Nantong University, Jiangsu Province, China
    BMC Infect Dis 12:130. 2012
    ..The aim of this study is to estimate the magnitude and changing trends of HIV, HCV and HIV-HCV co-infections among entry clients to MMT clinics in China during 2004-2010...
  83. pmc Designing equitable antiretroviral allocation strategies in resource-constrained countries
    David P Wilson
    Department of Biomathematics, AIDS Institute, School of Medicine, University of California, Los Angeles, California, USA
    PLoS Med 2:e50. 2005
    ..Deciding how to allocate the limited supply of ARVs among HCFs will be extremely difficult. Resource allocation decisions can be made on the basis of many epidemiological, ethical, or preferential treatment priority criteria...
  84. doi request reprint Replacement of conventional HIV testing with rapid testing: mathematical modelling to predict the impact on further HIV transmission between men
    David P Wilson
    National Centre in HIV Epidemiology and Clinical Research, University of New South Wales, Sydney, Australia
    Sex Transm Infect 87:588-93. 2011
    ..Rapid HIV testing is not permitted in Australia at the point of care. The authors evaluate the expected net effect of rapid HIV testing compared with standard serology diagnostic tests in terms of onward HIV transmission...
  85. ncbi request reprint Mathematical models and health economic aspects of microbicides
    David P Wilson
    aNational Centre in HIV Epidemiology and Clinical Research, Faculty of Medicine, University of New South Wales, Sydney, Australia bCenter for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine, Philadelphia, USA
    Curr Opin HIV AIDS 3:587-92. 2008
    ..Models of microbicide cost-effectiveness provide important perspectives in guiding access to future microbicides...
  86. ncbi request reprint A kinetic model of bone marrow neutrophil production that characterizes late phenotypic maturation
    Yishay Orr
    Department of Haematology, Prince of Wales Hospital, and Centre for Vascular Research, School of Medical Sciences, The University of New South Wales, Anzac Parade, Kensington, NSW, Australia
    Am J Physiol Regul Integr Comp Physiol 292:R1707-16. 2007
    ..4 h of maturation...
  87. pmc Allocating antiretrovirals in South Africa: using modeling to determine treatment equity
    David P Wilson
    PLoS Med 2:e155; author reply e186. 2005
  88. pmc Rational choices for allocating antiretrovirals in Africa: treatment equity, epidemiological efficiency, and feasibility
    David P Wilson
    PLoS Med 3:e160. 2006
  89. ncbi request reprint Evaluating the potential impact of vaginal microbicides to reduce the risk of acquiring HIV in female sex workers
    Robert J Smith
    Department of Biomathematics and UCLA AIDS Institute, David Geffen School of Medicine at UCLA, Westwood, California 90024, USA
    AIDS 19:413-21. 2005
    ..FSWs) acquiring HIV? Which factor would it be most important to maximize, microbicide efficacy or microbicide use? What level of microbicide efficacy and use would be necessary to counterbalance a possible reduction in condom use?..
  90. ncbi request reprint Australian migration policy of HIV-infected individuals requires renewed discussions
    David P Wilson
    Aust N Z J Public Health 31:385-6. 2007
  91. ncbi request reprint Type III secretion à la Chlamydia
    Jan Peters
    Department of Biomedical Sciences, University of Maryland, Baltimore, MD 21201, USA
    Trends Microbiol 15:241-51. 2007
    ..A general mechanism is emerging whereby both early- and mid-cycle T3S-mediated activities and late T3S inactivation upon detachment of chlamydiae from the inclusion membrane are crucial for chlamydial intracellular development...
  92. ncbi request reprint Microbicides: anti-HIV efficacy and ethics
    David P Wilson
    Science 306:1890; author reply 1890. 2004
  93. ncbi request reprint Response to Foss et al., 'Care should be taken when promoting microbicide use among sex workers who are able to use condoms consistently'
    David P Wilson
    AIDS 19:2044-6. 2005