Jonathan J Wilksch

Summary

Affiliation: University of Melbourne
Country: Australia

Publications

  1. pmc MrkH, a novel c-di-GMP-dependent transcriptional activator, controls Klebsiella pneumoniae biofilm formation by regulating type 3 fimbriae expression
    Jonathan J Wilksch
    Department of Microbiology and Immunology, The University of Melbourne, Parkville, Victoria, Australia
    PLoS Pathog 7:e1002204. 2011
  2. pmc Positive autoregulation of mrkHI by the cyclic di-GMP-dependent MrkH protein in the biofilm regulatory circuit of Klebsiella pneumoniae
    Jason W H Tan
    Department of Microbiology and Immunology, The University of Melbourne at The Peter Doherty Institute for Infection and Immunity, Parkville, Victoria, Australia
    J Bacteriol 197:1659-67. 2015
  3. pmc Transcriptional activation of the mrkA promoter of the Klebsiella pneumoniae type 3 fimbrial operon by the c-di-GMP-dependent MrkH protein
    Ji Yang
    Department of Microbiology and Immunology, The University of Melbourne, Parkville, Victoria, Australia
    PLoS ONE 8:e79038. 2013
  4. doi request reprint Influenza A virus facilitates Streptococcus pneumoniae transmission and disease
    Dimitri A Diavatopoulos
    Department of Microbiology and Immunology, University of Melbourne, Melbourne, Victoria, Australia
    FASEB J 24:1789-98. 2010

Collaborators

Detail Information

Publications4

  1. pmc MrkH, a novel c-di-GMP-dependent transcriptional activator, controls Klebsiella pneumoniae biofilm formation by regulating type 3 fimbriae expression
    Jonathan J Wilksch
    Department of Microbiology and Immunology, The University of Melbourne, Parkville, Victoria, Australia
    PLoS Pathog 7:e1002204. 2011
    ..pneumoniae to promote biofilm formation to implanted medical devices...
  2. pmc Positive autoregulation of mrkHI by the cyclic di-GMP-dependent MrkH protein in the biofilm regulatory circuit of Klebsiella pneumoniae
    Jason W H Tan
    Department of Microbiology and Immunology, The University of Melbourne at The Peter Doherty Institute for Infection and Immunity, Parkville, Victoria, Australia
    J Bacteriol 197:1659-67. 2015
    ..Increased MrkH production subsequently drives mrkABCDF expression when activated by c-di-GMP, leading to biosynthesis of type 3 fimbriae and biofilm formation...
  3. pmc Transcriptional activation of the mrkA promoter of the Klebsiella pneumoniae type 3 fimbrial operon by the c-di-GMP-dependent MrkH protein
    Ji Yang
    Department of Microbiology and Immunology, The University of Melbourne, Parkville, Victoria, Australia
    PLoS ONE 8:e79038. 2013
    ..Taken together, our results suggest that MrkH activates mrkA expression by interacting directly with RNA polymerase, to overcome the inefficient transcriptional initiation caused by the presence of defective core promoter elements. ..
  4. doi request reprint Influenza A virus facilitates Streptococcus pneumoniae transmission and disease
    Dimitri A Diavatopoulos
    Department of Microbiology and Immunology, University of Melbourne, Melbourne, Victoria, Australia
    FASEB J 24:1789-98. 2010
    ..Together, these data provide novel insights into pneumococcal-influenza synergism and may indicate a previously unappreciated role of IAV in the spread of S. pneumoniae...